Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

Environmental factors play a quintessential role in affecting our health. Fresh air, fresh food and fresh water, not only strengthen our body and mind but also make our life worth living. Contrary to this bad environment hampers the quality of life. This is the main reason why people from hill stations or the countryside seem to be healthier than those living in polluted urban cities. Following are the environmental factors that affect your health:

Polluted air

The health effects of polluted air are several. Not many people know that one-third of the deaths are caused because of strokes, lung cancer and heart failure. Air pollution is the chief reason behind these chronic ailments. The other life-threatening diseases caused by polluted air is- asthma or bronchitis. Smoke from machines, vehicles outside, and stoves, the burning of fuels inside can cause breathing problems and wheezing. 

Dirty environment

A dirty environment often leads to the breeding of insects and bacteria that become carriers of life-threatening diseases such as dengue, typhoid, diphtheria, malaria, and so on. Most of the diseases mentioned here are caused by mosquitoes that thrive on stagnant water.

Toxic food ;

The environmental quality of a region has a direct impact on the food produced in that area. Both vegetarian and non-vegetarian food faces the danger of becoming toxic if the environment it is being grown in is polluted. For eg- chemical wastes that are often dumped in water bodies cause the seafood in that area to become highly toxic.

Chemical pollutants

Cancer nowadays is becoming a household disease. The major reason behind this is that technological development has brought new categories of pollutants. Many of these contain chemicals and compounds that are carcinogenic in nature. This ultimately leads to the development of cancer in most people. 

Climate change and natural calamities

Change in climate disrupts the functioning of nature in many ways that further impact the health of humans. These changes include- the natural temperature of the planet, heavy rainfalls and sandstorms. The numerous impacts of climate may result in a high risk of nervous and respiratory diseases. ;

Hence protecting the environment is extremely important for the life of a human being. The change will come after taking small steps. Numerous small steps can really make a difference. 

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Environmental Factors That Affect Health

Hepatitis- related to an inflammatory condition of the liver. It occurs mainly due to infection caused by viruses but there are other possible causes as well. Hepatitis can be temporary or viral. Temporary hepatitis, which is acute in nature, gets resolved on its own. Viral hepatitis can be of five types, a, b, c, d, and e.

Symptoms of hepatitis

Hepatitis, in its initial phase, is called the acute phase. The following symptoms along with mild flu are visible:

Loss of appetite
Fatigue
Joint pains
Pain in the abdomen
Nausea
Weight loss
Jaundice
Though this phase is not really dangerous for some patients, it can result in liver failure leading to death.

How is hepatitis diagnosed?

Physical examination
Laboratory tests
Imaging tests


Treatment for hepatitis

Treatment options for different types of hepatitis are:

Hepatitis a: this doesn t require treatment as it is short-term in nature. In case the symptoms cause a lot of discomforts, then bed rest is recommended. The vaccine is available to prevent this infection.

Hepatitis b: acute hepatitis b doesn t require treatment either. Its chronic form can be treated with antiviral medications. This can be prevented with vaccination.

Hepatitis c: this type of hepatitis, both in its acute and chronic forms, is treated through antiviral medications.

Hepatitis d: according to a study in 2013, a drug known as alpha interferon is used to treat this type of hepatitis. Unfortunately, this only comes to the rescue of 25-30% of people.

Hepatitis e: this acute form of hepatitis gets resolved on its own. Adequate rest, drinking a sufficient amount of water, and taking enough nutrients in their food are some of the ways to get healed from this disease.


 

Hepatitis: Signs, Diagnosis, And Treatment

World environment day is celebrated annually on 5th june. This day encourages awareness and action for the protection of our environment. It raises the problems facing our environment such as plastic pollution, air pollution, illegal wildlife trade, sea-level increase, sustainable consumption, and food security, among others. 

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World environment day is a reminder for us to pause and reflect on our actions and their subsequent consequences on the planet. 

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When was the world environment first celebrated?

The day was first observed in 1974 in the city of spokane in the usa.

 

History of world environment day (wed)

1972- the un general assembly established world environment day on the 1st day of the stockholm conference on the human environment. ;

1974- the first" world environment day" was held with the theme" only one earth. 

1987- the idea for rotating the center of these activities by selecting different host countries began. ;

 

Why is world environment day celebrated? ;

For a healthy life, the environment plays an important role. It provides us with air, food, etc. The environment is like our neighborhood, its surrounding conditions affect us and also modify development. It is really necessary to address the environmental issues like deforestation, increasing global warming, pollution, wastage and losses of food, etc. Currently, our earth is experiencing a triple planetary emergency: 


	
	Pollution is poisoning our air, land and water. ;
	
	
	Climate is heating up too quickly
	
	
	Habitat loss
	


The deteriorating environmental conditions worldwide had already raised alarms in academic circles, among scholars studying its conditions. However, general masses seemed oblivious to changes that were not directly affecting them.

The world environment day is structured in a manner that allows one country to take up the responsibility of selecting the theme and hosting the key celebrations each year. 

Let's all come together and ensure this unique and beautiful planet remains a comfortable home for humanity. 

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World Environment Day: What Is World Environment Day And Why It Is Celebrated? 

If you have diabetes, many parts of your body are likely to get affected over time. You might observe that your digestion is not the same as it was before you had diabetes. In this case, you are likely to face stomach problems and bowel issues. This is due to the effect of diabetes on your vagus nerve.

The vagus nerve is responsible for managing the complex processes in your digestive system. When the nerve is not functioning properly, your digestion slows down. As a result, the contents of your stomach stay longer than they should. Such a condition is called diabetic ;gastroparesis, which is one of the most common diabetic problems.

What is diabetic gastroparesis?

In gastroparesis, your stomach takes too much time to clear the bowel due to disrupted digestion. Usually, after a meal, the vagus nerve helps to contract the stomach muscles to break down the food into smaller pieces and pass it to the small intestine.

However, if the nerve is damaged, the muscle contraction gets halted and the decomposition of the food is slowed down. This condition is common in patients suffering from type 1 and type 2 diabetes. This is because diabetes causes nerve damage, which in turn damages the vagus nerve.

Symptoms of gastroparesis

The most common symptoms of the condition are  


	
	Heartburn
	
	
	Nausea accompanied by ;vomiting
	
	
	Appetite loss
	
	
	Bloating in the abdomen
	
	
	Acid reflux
	
	
	Weight loss
	
	
	Fluctuations in the blood ;sugar level
	
	
	Feeling full even after consuming a little amount of food
	
	
	Spasms in the stomach
	


What are the treatment options?

The first step to treat diabetic gastroparesis is to manage the levels of blood sugar. In this case, your doctor might ask you to check your blood sugar regularly   that will help him to modify the treatment to cure this condition.

The treatment can include the following steps  


	
	Altering your insulin dosage and the number of times you take it
	
	
	Oral medication may be prescribed to improve the condition
	
	
	Gastric ;electrical stimulation   where a device called gastric neurostimulator is implanted in the lower abdominal region. It sends low energy electrical impulses to your stomach muscles to cure cases of severe vomiting and nausea.
	


The doctors will recommend some dietary changes   avoid fibre-rich foods and include low-fat foods instead. With proper treatment and lifestyle changes, diabetic patients may be able to avoid common digestive problems like gastroparesis.

What Is Gastroparesis- A Diabetes Induced Digestive Problem

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