Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

The 4 types of kidney stones and their common symptoms

Defined as hard and small mineral deposits that develop inside your kidney, kidney stones are made up of acid salts and minerals. The causes of this disease are not well-defined, although risk factors include drinking very little amounts of water and having a diet rich in sodium, protein and oxalate (chocolate and green leafy foods for example). However, knowing the type of kidney stone you suffer from can help ascertain the cause.

Here are the common types of kidney stones.

Struvite stones

This type of kidney stone is usually a response to certain kind of infection, such as a urinary tract infection for example. Characterised by rapid growth and a large size, struvite stones can develop without any warning signs.

Calcium stones

These are the most common type and are caused by a diet rich in oxalate. Risk factors for calcium stones include a diet consisting of plenty of nuts, chocolates and certain fruits and vegetables; metabolic disorders, high doses of vitamin d and intestinal bypass surgery, all of which can increase the amounts of calcium or oxalate in your urine, indicating the development of kidney stones.

Cystine stones

Those individuals with a hereditary disorder that causes their kidneys to produce certain amino acids (cystinuria to be precise) in excess are most likely to get cystine stones.

Uric acid stones

These are common in those whose diets are lacking in water or those who suffer from the excess fluid loss. People with a high protein diet and those who suffer from gout are also at risk. Genetic factors play a major role as well in increasing your risk of getting uric acid stones.

Apart from these, there are other rarer types of kidney stones that can also arise depending on a combination of an individual's lifestyle and genetic make-up.

However, to determine whether you're suffering from any of the aforementioned types of kidney stones, you must first know its common symptoms, which are:

  excruciating pain in your sides, and back, especially below your ribs

  feelings of pain in the groin and the lower parts of your abdomen

  intense and fluctuating pain that comes and goes in waves

  pain while urinating

  urine that is red, brown or pink in colour
  urine that's cloudy or has a foul odour

  vomiting and nausea

  constant urge to urinate

  increased frequency of urination

  urinating in small amounts

  chills and fever in case of an infection

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Related Tip: 20-Year-Old Indians Experiencing Kidney Failure! 4 Killer Reasons.

4 Types of Kidney Stones and Their Common Symptoms

Diabetes is a lifestyle disease that is very prevalent in the current generation. According to a report by the World Health Organisation (WHO), the number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% to 8.5% from 1980 to 2014. Diabetes should not be taken lightly as it can affect other body organs besides the pancreas, such as the kidneys. Diabetic nephropathy refers to damage to your kidneys caused by diabetes, and may also lead to kidney failure in various cases.

Causes of diabetic nephropathy
Not everyone who suffers from diabetes will suffer from diabetic nephropathy. The main function of the kidneys is to filter waste from your blood. However, this is not always the case. Due to high a concentration of blood sugar caused by diabetes, several blood vessels in the kidney are destroyed, thereby, preventing the kidneys from carrying out its job. Over time, the kidneys may stop working altogether, resulting in kidney failure. If you are diabetic, the probability of you suffering from diabetic nephropathy will increase if you smoke or have high blood pressure or high cholesterol.

Catching it early
Today, diabetic nephropathy is the leading cause of chronic kidney disease in the US and other western countries. Since the symptoms of this condition aren t visible in its early stages, you need to undergo urine tests on a regular basis. If detected early, the effects of diabetic nephropathy can be reversed. Common symptoms of this disease include the following:

Swelling in legs and feet
Detection of albumin in urine
Decline in glomerular filtration rate (GFR)
Elevated arterial blood pressure
What are the treatment options?
Medication to lower the blood pressure is the most commonly prescribed form of treatment suggested by doctors to prevent or slow the damage to your kidneys. There are other lifestyle changes that you may have to undertake in order to keep a check on the condition:

Limit sugar intake and keep blood sugar levels within the target range
Exercise regularly and work towards keeping your heart healthy
Limit protein intake, as it could put extra pressure on your kidneys
Limit salt intake to control blood pressure
Quit smoking and drinking
Diabetes is an unfortunate condition to have to live with. But don t let it bog you down! With these simple lifestyle changes and taking care of your general well-being, you can beat the disease and emerge a winner!

Diabetic Nephropathy - Who is at Risk of Acquiring it?

The pair of kidneys that human beings have, forms an important part in the excretory system. They perform specific and important functions. They excrete urine as well as help in eliminating the toxins, which accumulate in the body. Kidney stones occur when the minerals present in the urine without being discharged, keep on accumulating. This gives rise to an extremely painful and uncomfortable situation. Though sometimes the situation gets revoked all by itself, many a times it requires medical intervention. 

Some of the symptoms of kidney stones are: 
1.  Excruciating pain in the back
2.  Pain while urinating
3.  Tendencies to vomit
4.  Dizziness
5.  Fever 

However, there are several preventive measures which you can undertake in order to avert the situation. Some of them are:
1.  Drink lots of water
Kidney stone is one of those rare conditions that once occurred, always carry the latent threat of recurring again. Therefore, drinking water in large quantities becomes essential. The more you drink water, the more frequently you would urinate, thereby curbing the chances of the minerals settling in the kidneys.
2.  Avoid certain foods
Food like beets, spinach, those which are replete with calcium oxalate should be avoided in order to minimize chances of having kidney stones.
3.  Change your diet
If you are trying to avoid the eventuality of developing kidney stones, it is imperative that you change your diet a bit. It is recommended that you exclude animal protein as much as possible and assiduously avoid the intake of salt as much as possible.
4.  Take less calcium supplements
Calcium generally is considered a nemesis to your kidneys and is prescribed by doctors to be avoided. However recent research has thwarted this claim. Calcium does not pose a threat to kidneys. However calcium supplements definitely do and therefore, should be avoided.

All About Kidney Stones

Kidney stones can range from being the size of a grain to a pebble. These stones can be described as crystallized mineral deposits in the kidneys. Some kidney stones can be passed out of the body along with urine while others may require surgery. Symptoms of having a kidney stone vary from mild to severe. In the case of very small kidney stones, the patient may not experience any symptoms at all. The 5 most common kidney stone symptoms usually experienced are:

Pain: Pain in the lower abdomen and back is one of the most common symptoms of having a kidney stone. This may be felt just below the ribs, on the centre and sides of the abdomen, in the lower back and in the groin. The intensity of pain is not directly related to the size of the kidney stone. This pain can come and go and will vary in terms of intensity. In certain cases, the pain can be severe enough to warrant a trip to the hospital. This pain is usually a sign that the stone is moving.
Frequent Urination: People suffering from kidney stones may find themselves needing to go to the bathroom more often than normal. In some cases, patients may also wake up in the middle of the night with the urge to urinate. However, only a small amount of urine may be passed at a time. This is a sign that the kidney stone has moved into the lower urinary tract. Small stones may later be passed out of the body along with urine.
Bloody Urine: Urine should ideally be pale yellow. Patients suffering from kidney stones may notice that their urine is darker than normal and cloudy. There may also be blood in the urine. This is known as hematuria. The colour of blood in such cases can range from pink to brown. Cloudy urine is also considered a sign of a urinary infection. This is a sign that the urine also contains pus cells or pyuria.
Nausea: Vomiting and nausea are common symptoms of kidney stones. This is caused by the nerve connections shared by the kidneys and the gastrointestinal tract. The presence of kidney stones in the kidneys or urinary system can trigger an upset stomach. Some people also feel nauseous because of the pain caused by kidney stones.
Foul Smelling Urine: Under normal conditions, urine should not have a very strong smell. Urine that smells bad is a symptom of a urinary infection. Bacteria in the kidneys or urinary tract can be the cause of this smell. It may also be caused by the high concentration of urine. 

5 Symptoms Of Kidney Stones!

A kidney transplantation is a surgical procedure where a diseased kidney is replaced with a healthy one.

Once the surgery is over and you are recuperating, it is very important that you make certain alterations to your diet to facilitate faster recovery. You need to maintain your weight and exercise on a regular basis.

What Does a Balanced Diet Include?

After the surgery, eat meals or food items that are low in sodium. A properly balanced diet should include ample amounts of fresh fruits, lean meats, fresh vegetables, dairy products that are low in fat. Drink sufficient amount of water (2-3 litres) to keep yourself hydrated.

Why Do You Need to Supervise Your Diet?

Post a kidney transplantation surgery the patient will need to take anti-rejection drugs which are also known as immunosuppressive drugs. These medications lower the risk of the new kidney being rejected by the body. On the flip side, these drugs suppress the immune system making you vulnerable to infections. A healthy diet will ensure that you don t fall ill.

What Food Items Should You Avoid?

  Consuming undercooked or raw meat, poultry and seafood such as squid, crabs or prawns.
  Consuming dairy products that have been made from unpasteurized milk such as yoghurt and cheese.
  Undercooked or uncooked eggs or any food items that might contain such eggs
  Fruits such as pomegranates or grapefruits
  Unwashed salads, sprouts and vegetables.

Restrain Caution when Consuming Carbohydrates:

When you are taking drugs, it is difficult for the body to utilize all the extra carbohydrates that you consume. This can lead to high blood sugar levels. Carbohydrate-laden food items come from starches and sugars and provide fuel for the body.

In short right after a kidney transplantation surgery, you need to make sure that you are following a diet that is high in proteins but low in sugar. In order to avoid developing diabetes or any associated disease during this phase consult with your healthcare provider and chalk out a proper dietary plan.

Nutrition After Kidney Transplant!

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