World Sickle Cell Day is observed each year on June 19th to raise the public awareness regarding this disease and its treatment methods. Sickle Cell disease is an inherited transmitted deformity/abnormality of haemoglobin. It is an inherited form of anaemia. This abnormality generates changes in the shape of red blood cells from round to crescent, which reduces the oxygen carrying capacity and slows down the flow of blood to various parts of the body. 

Generally, red blood vessels are round and flexible, passing easily through the blood vessels. The red blood cells become sticky and rigid in sickle cell anaemia. Sickle cells last 10 to 20 days, which causes anaemia because of the disorder of red blood cells, while healthy red blood cells could live up to 120 days.

Millions of people around the world are affected by Sickle Cell Anemia. There is no specific cure for this disease as Sickle cell anaemia is not contagious, it is hereditary. Sickle cell anaemia is named so for the reason that red blood cells are crescent-shaped or sickle-shaped, and anaemia signifies lack of blood. There is a difference between iron-deficiency anaemia and sickle cell anaemia.

Symptoms

Sickle Cell Disease (SCD) has many symptoms which includes: serious anemia, episodes of suffering, additionally a range of complications, heart failure, dizziness, chronic kidney disease (CKD), acute chest syndrome (ACS), chest pain, gallstones, pulmonary hypertension, immune deficiency, paralysis or stroke, splenomegaly, joint damage mainly in the hip joint, foot ulcers, delayed puberty, retinopathy, and endocrine disorders.

Diagnosis

Sickle Cell Disease is diagnosed by blood tests.

Treatment

Bone marrow transplant or stem cell transplant in patients usually below the age of sixteen is the only available cure for the disease.

Aim of the World Sickle Cell Day

The aim of the World Sickle Cell Day is to support and promote research for the patients in order to help them upgrade their overall quality of life to the maximum possible extent. It also aspires to increase awareness for sickle cell disease disorder in the general public so that they know how to deal with patients suffering from the disease. Moreover, the World Sickle Cell Day has the objective of raising awareness of the importance among generations of pre-marital screening to lessen the transmission of Sickle Cell Disease.

Target Groups for Awareness Programs

Though it is desirable that everybody knows about Sickle Cell Disease, the target groups for the awareness programs include health decision-makers, sickle cell anaemia sufferers and their families, health organizations and associations, people who are planning to get married, and the health workers including health educators, physicians, and nurses.

On the World Sickle Cell Day, different societies provide advocacy, information, and advice for raising awareness. They also provide educational and welfare grants, support services, annual children s holiday, home help, hospital visits, mentoring and befriending through holding talks, assisting into research and training, lobbying for better service provision, patient education seminars, and campaigning.

World Sickle Cell Day - What Should You Know?

What is anemia?

Anemia is due to lack of haemoglobin in the blood which is below the normal level or due to less than normal levels of red blood cells in blood.

The haemoglobin helps carry oxygen in blood. Lack of haemoglobin thus causes deficiency of life giving oxygen to vital organs. (1-4)

Types of anemia

There are various causes of anemia. It could be due to:

Decreased production of RBCs in blood
Increased blood loss OR
Excessive destruction of RBCs
Causes of anemia
Anemia most commonly occurs due to nutritional problems. This includes lack of iron in the diet.
Iron deficiency is the commonest form of anemia.
In the United States 7% of toddlers ages 1 to 2 years old and 9-16% of menstruating women suffer from iron deficiency.
The poorer nations 30-70% of the people have iron deficiency anemia.
Iron and anemia

Since iron is needed for the manufacture of haemoglobin in the body its deficiency can lead to anemia.
Iron is found in meat, dried fruit and some vegetables.
Lack of iron may be caused due to bleeding especially in stomach ulcers or within the intestines.
Women before menopause commonly suffer from iron deficiency anemia due to heavy periods and increased demands during pregnancy.
Vitamins and anemia

Certain vitamins like vitamin B12 and folic acid or folate are also essential in the normal production of RBCs in blood. Their lack in diet may lead to anemia.
Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people above the age of 75.
There is an inherited condition called Pernicious anemia where patients find it difficult to use the vitamin B 12 in diet for production of healthy RBCs. This is a rare condition and affects 1 in 10,000 people in northern Europe.
Other causes of anemia

Increased blood loss due to surgery or major trauma may lead to anemia.
Excessive destruction of RBCs may occur due to certain conditions called haemolytic anemias. These are often inherited and include Sickle cell anemia, Thalassemia etc. Anemia can also occur in severe infections, cancers and due to exposure to a drug or toxin.
For example, the RBCs are made in bone marrow. If there is cancer in the marrows a shortage of good red blood cells results. This is called aplastic anaemia and may also occur with blood cancers like leukaemia.
Symptoms

Anemia signs and symptoms vary depending on the cause of your anemia. They may include:

Fatigue
Weakness
Pale or yellowish skin
Irregular heartbeats
Shortness of breath
Dizziness or lightheadedness
Chest pain
Cold hands and feet
Headache
At first anemia can be so mild that it goes unnoticed. But symptoms worsen as anemia worsens.

Treatment of anemia

Treatment depends on the cause of the anaemia. If the anaemia is due to a lack of iron, eating iron-rich food or iron supplements may be given. If, however, the cause of anemia is deeper like internal bleeding or cancers, the cause should be explored before treatment. When the anaemia is more severe, a blood transfusion may be prescribed.

Anemia - Causes, Symptoms & Treatment Of It!

A healthy kidney produces a hormone known as the erythropoietin. The latter assists the bone marrow to produce an adequate amount of RBC that carries oxygen to every nook and corner of the body. A damaged kidney results in less RBC production, thereby, creating a condition known as anemia. The hemoglobin count in the blood reduces significantly in this condition.

Anemia is characterized by shortness of breath, weakness and tiredness. It can affect sleep and a loss of appetite. A patient suffering from anemia reports of frequent headaches and a faster heart rate. These symptoms also surface when a person suffers from chronic kidney diseases (CKD). The condition gets worse as the disease progresses.

Treating anemia:
A patient suffering from anemia should be treated on time as there are many pitfalls of a lower hemoglobin level. The treatment will give instant relief from other symptoms that might have arrived with CKD. Doctors frequently prescribe Erythropoiesis Stimulating Agent (ESA) for patients suffering from CKD and suffering from anemia due to the shortage of erythropoietin. ESAs can be injected through an injection or intravenously. These injections stimulate the bone marrow to produce more RBCs. However, studies have revealed that ESAs increase the chance of strokes, heart attacks and blood clots. Furthermore, they aggravate tumor growth and shorten life expectancy for cancer patients. People undergoing ESA treatment should have periodic check-ups to ensure that the hemoglobin count is normal and under control.

Iron
Iron count in the body has an important role in treating patients suffering from anemia and CKD. In case the level of iron is too low in the body, ESAs fail to improve the condition of an anemic patient. The ferritin count of a patient should be in the range of 100-800 mcg/L. One more test known as TSAT reveals the number of iron required to produce RBCs in the body. In case the iron count is less, doctors often suggest iron pills to bring the count to a more accepted level.

Other causes
There could be other reasons for anemia as well. A doctor might further investigate the level of B12 and folic acid present in the body. Even an inflammatory condition can lead to anemia. A decreased count of any of the above-mentioned ingredients can cause anemia to a patient suffering from EKD.

Food items necessary to improve the condition
A healthy diet helps in improving the condition of an anemic patient. Iron deficiency is best addressed by fish and beef. Food rich in vitamin C helps the body to absorb more iron in the body. Certain food items that block the entry of iron in the body include tea, milk, albumen (egg white) etc. Therefore, you should be strictly avoid these items from your diet.

Kidney Disease - How It Is Related With Anaemia?

Anemia is a condition where the red blood cell count is reduced due to deficiencies within the system. This is usually caused by a lack of iron, folate and other related nutrients in the diet. Anemia is a major public health concern in India as over 50 percent of women are known to be anemic. This pushes up the mortality rate of young mothers and even children.

Some symptoms of Iron deficiency anemia
Anemia has a wide range of symptoms which varies from person to person. However there are some generic symptoms which can be noticed in most people. Some of these are
1. Pale appearance of skin - Many people exhibit this symptom where their skin appears to be pale as there is a reduced amount of oxy - hemoglobin in the skin.
2. Physical weakness, light headedness and fatigue - This is a general symptom, which many tend to suffer from and complain about. Fatigue and weakness may come in very quickly even with the slightest effort.
3. Hair loss - Many women may complain about hair loss due to Iron deficiency  anemia.

Some other symptoms are -
a. Breathlessness
b. Constipation
c. Missed or irregular periods
d. Numbness or burning sensations
e. Depression
f. Tinnitus among others

Causes of Iron deficiency anemia
The primary cause of Iron deficiency anemia is the lack of iron in the diet which causes the hemoglobin in the blood to be reduced. Some of the patients may still have Iron deficiencyanemia as they have developed gastrointestinal disorders which prevents the absorption of nutrients like iron within the body.

How to treat Iron deficiency anemia
Diet related anemia can be easily cured or controlled with changing diets. Inclusion of certain foods within the diet can easily reverse the Iron deficiencies. Some of the food items that help with deficiencies are:
1. Fortified cereals
2. Green dark leafy vegetables
3. Poultry items
4. Eggs
5. Meat
You may also require certain iron supplements if you have certain underlying conditions which is causing issues with iron absorption.

How to prevent Iron deficiency anemia
It is important, especially for women to go for regular checkups to your doctor and also a hemoglobin check up. Your doctor or dietician can tell you to include certain foods in your diet that include folate, iron and vitamin B 12 so that the level of hemoglobin in your blood can be maintained at healthy levels.

All About Iron Deficiency - Anemia

In this fast-moving world, everyone is so busy that it's hard to take self-care. People give less importance to what they eat, when they sleep and so on. Conditions such as anaemia have become very common, and we still neglect knowingly and unknowingly. You tend to find quick alternatives. Homoeopathy is the alternative for such a condition.

Understand Anemia

If hemoglobin (that carries oxygen throughout the body) count is less in red blood cells, such condition is known as anaemia. Body doesn't receive enough oxygen, thereby leading to weakness and fatigue. Anaemia can affect all age groups; from kids to elders.

Apart from poor diet, certain anaemic conditions could be hereditary, which are beyond one's control. Women who are of childbearing age tend to be anaemic due to menstruation.

Causes and Types
- Accidental blood loss, child birth or medical conditions such as gastric ulcer lead to haemorrhage, which ultimately lead to anaemia.
- Iron deficiency during pregnancy, poor diet or haemorrhage may cause anaemia
- Megaloblastic anaemia occurs due to deficiency of Vitamin B12 (Folic Acid).
- Pernicious anaemia occurs due to autoimmune disorder. One is unable to absorb Vitamin B12 adequately.
- Hemolytic anaemia is caused to destruction of red blood cells during ill health conditions such as in malaria or due to irregular red blood cells such as in Sickle-Cell Anemia.
- In a condition where haemoglobin production is impaired due to hereditary disorder, it is called Thallasemia.

Homeopathic Remedy
There are numerous homeopathic treatments available for anaemia.

1. Aletris Farinosa is mainly given to women who are extremely weak and feel tired. Such patients always feel tired with minimal energy levels. Vertigo and fainting are quite common. Facial skin looks pale.
2. China is the best for one who experiences excessive bleeding. Bleeding could be due to traumatic injury, periods and so on. The person is usually tired and faints quite often. China is used to control haemorrhage as well as improves blood quantity after bleeding episodes.
3. Cinchona also helps to treat anaemia due to blood loss.
4. Ferrum Metallicum is considered to be the best homeopathic medicine for anaemia.
5. Natrum Mur helps to treat anaemia due to grief. Reasons could be personal tragedy or any other circumstance. The condition worsens due to heat. One tends to ingest more of salt content food.
6. Nit-acid-One is given to anaemic persons who have a desire to eat chalk, paper and earth.

Besides these treatments, eat iron-rich food and have a regular blood check-up at least once in six months.

Homeopathy Medicines to Treat Anemia

Your body goes through drastic changes when you are pregnant. Your body makes more blood during pregnancy; for instance, prior to pregnancy, your body made approximately 5 litres of blood, but now it produces 7 to 8 litres of it.
Producing excess red blood cells requires haemoglobin, which in turn requires plenty of folate, iron and vitamin B12. If there is a deficiency in any of these requirements, you might develop anaemia.
Anaemia is a condition, which is characterized by a lack of red blood cells in the body. The risks of becoming anaemic during pregnancy include:
1. Being extremely fatigued
2. Miscarriages, premature birth, or low birth-weight
3. The baby can inherit anaemia from the mother
4. The child can have certain developmental delays
5. Postpartum depression (post-childbirth depression)

How it can be prevented?
To prevent such risks, it is important to implement the proper diet. Here are some dietary tips to prevent anaemia during pregnancy: 
1. Consume iron-rich foods: Foods that provide you with the best source of iron are 
i. Poultry and eggs
ii. Dark green and leafy vegetables (for example: spinach, broccoli and kale)
iii. Seeds and nuts
iv. Beans and lentils
v. Tofu
vi. Beetroot
vii. Ripe bananas

2. Don't forget the supplements: Foods are great sources of the nutrients you require, but they may be lacking at times. Ask your doctor for supplements like vitamin, folic acid and iron supplements mostly. Consuming supplements before pregnancy can go a long way in preventing anaemia.

3. Folic acid is important: Folic acid is very important for pregnant women. You must consume 400 milligrams of it to prevent anaemia and birth defects in babies. Foods that are rich in folic acid include:
i. Beans
ii. Muesli
iii. Broccoli
iv. Brussel sprouts
v. Asparagus

4. Vitamins are crucial: Vitamin C helps in iron absorption which boosts haemoglobin production. Some foods rich in vitamin C include
i. Citrus fruits
ii. Strawberries
iii. Kiwis
iv. Tomatoes
v. Bell peppers

5. Be vigilant while cooking: Sometimes while cooking foods, the wrong method can strip them of their iron content. So be careful not to fry, boil or stew such foods too much. Certain foods are best consumed raw; read the labels properly if in doubt.

6. Abstain from certain habits: Alcohol, tea, cigarette and coffee hinder iron absorption. So stop consuming them if you are trying to conceive or have conceived.

Dietary Tips to Prevent Anaemia in Pregnant Women

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