The body has multiple chemicals called hormones, which regulate many of its functions. Increased or decreased levels of these hormones affect various functions including metabolism, growth and sexual functions. Thyroxin produced by the thyroid (situated in the front of the neck) is one such hormone, which has a significant role to play in metabolism.

Graves  disease is one of the main causes of hyperthyroidism, where there is excessive production of thyroid hormones. Graves  disease is an autoimmune disorder, wherein the body reacts against its own tissues. It is very common in women than men, especially after 20 years of age. Family history also has a strong correlation in developing Graves  disease. The high levels of thyroid hormone increase the rate of metabolism, thereby altering weight, mental energy levels, physical stamina, and also mood.

Thyroid hormone is related to metabolism and more amount of it lead to higher metabolism. This causes the following symptoms.

    Intolerance to heat
    Excessive sweating
    Nervousness and anxiety
    Inability sleep, as the mind is always excited
    Increased appetite (sometimes despite weight loss) due to higher metabolism
    Irregular menstrual cycles
    Palpitations (rapid, loud heartbeat)
    Irregular heartbeats (tachyarrhythmia)
    Fine tremors of the extended arms
    Breast enlargement in men, known as gynecomastia
    Extreme moodiness, causing irritability and anger
    Inability to focus and concentrate
    General fatigue and shortness of breath with any exertion
    Increased frequency of bowel movements

In addition, the eye symptoms are quite diagnostic including:

    Protrusion of the eyes (exophthalmos), giving an impression that they are going to fall out
    Double vision
    Excessive tearing
    Increased irritation in the eyes

Diagnosis: The first symptom would be the presence of an enlarged thyroid gland (front of the neck above the collarbone), and the some of the above symptoms would be present.
In addition, tests to check for thyroid gland functioning including T3 and T4 levels would reveal increased amounts of hormone in the blood stream.
As a confirmatory test, the radioactive iodine uptake test also is done, which will indicate increased uptake by the thyroid gland. This indicates that the gland is functioning at an increased pace and requires additional iodine for the production of thyroid hormones.

Treatment: There are two approaches to it, one to control the symptoms and the other to control the thyroid gland per se.

    Beta blockers are very useful in controlling rapid heart rate and anxiety.
    Prednisone may be used to control eye irritation and swelling
    Antithyroid drugs are used to control the production of thyroid
    Radioactive iodine is given orally to control excessive thyroid production
    In severe cases, thyroid gland may be surgically removed partially or completely

Graves  disease is not life-threatening and once symptoms are controlled, the patient s quality of life improves drastically.

Graves' Disease - Things You Should Know About It

 Thyroid is a small gland situated in front of the neck and secretes hormones like thyroxine (T4) and tri-iodothyronine (T3). These hormones control various functions of our body like heart, blood pressure, digestion, metabolism, growth, blood formation, brain function etc. Any fluctuation in the functioning of the thyroid gland can have a great impact on health. The thyroid gland is primarily responsible for energy and metabolism. This gland triggers the genes that make all the cells in the body conduct their specific jobs. But over a period of time, the optimum functioning of the thyroid may reduce because of specific reasons. The gland may start to under-produce or overproduce the thyroid hormone, which may lead to conditions known as hypothyroidism or hyperthyroidism, respectively. 

Patients with hypothyroidism may feel extreme tiredness and fatigue even though they may be sleeping more than before. An unexplained gain in weight, constipation, inability to stand cold temperatures, and constant pain in muscles and joints are some of the other symptoms of hypothyroidism. 
Hyperthyroidism, or overactive thyroid, is an endocrine disorder. Patients with this disorder may experience excessive sweating, fatigue, and intolerance to heat. They may even experience restlessness, puffy or protruded eyes, hair loss, and muscle weakness. Such patients may lose weight and are unable to sleep properly at night. In some cases, palpitations or abnormal heart rhythm may also be experienced. 
Complications of Thyroid Disorder 

Hypothyroid and hyperthyroid can cause a number of complications if patients don t take medications. It is important for you to not to ignore any of the aforementioned symptoms and speak to your doctor as soon as possible. 

Hypothyroid complications

Myxedema: This condition is characterized by slowed thinking, swelling of tissues, and accumulation of fluid around major organs like brain, lungs and/or heart. This condition may prove life-threatening if not treated on time. 
Enlarged goiter: This is characterized by enlargement of the thyroid gland because of a constant increase in the TSH levels. High cholesterol and triglycerides: This may eventually pave way for heart disease and stroke. 
Sleep apnea: Sleep apnea is a disorder that affects nighttime breathing where the brain that temporarily stops sending signals to the muscles that control breathing, or by an obstruction in the airway. This may prove fatal if left untreated. 
Low blood pressure: This means not enough blood is getting to capillaries and tissues, particularly in your hands, feet, and brain. You may have chronic nail fungal infections and cold hands and feet if so. 
Hyperthyroid complications 

Heart disorders (cardiac arrest): If left untreated, excess thyroid hormones can lead to congestive heart failure and heart rhythm disorders. 
Osteoporosis: Too much thyroid hormones interfere with the body s ability to use calcium to build bone. This may lead to brittle bones and osteoporosis. 
Thyrotoxic crisis: This is a rare yet life-threatening complication characterized by high fever, vomiting, irregular heartbeat, and agitation. 
Hypertension or high blood pressure: It is a condition in which a patient has high blood force striking the walls of the artery An early diagnosis can help make the treatment of this disorder easier. 
Depending on the condition of the thyroid condition, it requires different ways to manage it. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered. In case you have a concern or query you can always consult an expert & get answers to your questions!

Is Your Thyroid Gland Working Against Your Body? 

Do you feel extremely tired many times in a day? Are you experiencing sudden weight gain, chills at night and hair loss? Is your neck a bit bloated up? If you are experiencing any of the mentioned symptoms, it might be that your body regulator- Thyroid- is unbalanced. Quick 3 tests can help you detect any abnormality - TSH, T3 and T4. Women were three times more likely to be affected by thyroid dysfunction than men. 1 in 10 adults in India suffers from hypothyroidism, with 50 per cent being women.

What is the thyroid gland?
The thyroid is a butterfly shaped gland in the front of the neck. It produces hormones that control the speed of your metabolism - the system that helps the body use energy. Thyroid disorders can slow down or rev up your metabolism by disrupting the production of thyroid hormones. When hormone levels become too low or too high, you may experience a wide range of symptoms.

What are the Symptoms?
Thyroid can be of 2 types - Hyper (Overactive) and Hypo (Underactive) Thyroid.
Low and Underactive Thyroid High and Overactive Thyroid
Fatigue Nervousness
Dry Skin & Hair Tremors - Hand Shaking
Brittle Hair Hair loss or thinning hair
Constipation Diarrhea
Low Pulse High Pulse
Weight Gain Weight loss without trying
Intolerance to cold temperature Intolerance to hot temperature
Depression Sweatiness
Swelling in lower part of neck Swelling in lower part of neck

The swelling in the neck is a major and most significant feature. Hence one should always do the Self Neck Test.

Who should be tested?
Women aged 35 and above or those with symptoms/risk factors/family history are the right candidates for screening. It has been estimated that 75% of the people suffering from thyroid are undiagnosed.

Diagnosing thyroid disorders - A simple blood test can provide an answer. TSH (Thyroid Stimulating Hormone) levels determine thyroid hypo and hyper function as it regulates the work of thyroid gland. Rarely an imaging study or biopsy is needed. Two additional tests may be required - T3 and T4.

What happens if Thyroid remains undetected?
As Thyroid disorders are hormonal imbalances, undetection can lead to a number of secondary complications:
Obesity
High Cholesterol and Hypertension
Hair Fall
Heart Disease
Complications in pregnancy

Understanding Thyroid Problems in Women: Did You Get the Test Done?

The thyroid hormones, namely T3, T4 and TSH (Thyroid Stimulating Hormone) play a pivotal role in various metabolic processes in the body. Any imbalance in the level of these hormones can interfere with the normal body functions. While an elevated level of the thyroid hormones gives rise to Hyperthyroidism, a reduced level of the same thyroid hormones can lead to a condition medically termed as Hypothyroidism. A proper diagnosis and treatment can bring about a significant improvement. However, there are some common mistakes that many people with thyroid problems often make.

Choose your diet with care: The health benefits of a balanced and nutritious diet are known to all. However, a food considered healthy may not be an ideal choice for a thyroid patient. Time and again, broccoli and kale have been recommended for its nutritive value. However, these vegetables may not be a good choice for thyroid health. Known to contain goitrogens, they may interfere with the production of the thyroid hormones. Gluten, a protein present in wheat, rye, and barley, though healthy should be avoided, especially in the case of Hypothyroidism.
Obesity may not be the trigger: While it is a healthy practice to maintain a healthy body weight, it is unfair to blame the extra kilos for every single disease that you suffer from. Many people believe that losing weight is the best way to deal with thyroid problems. However, the fact is quite different from what you believe. Thyroid problems can be an outcome of various triggers where losing weight may provide negligible or no assistance to reverse or improve the condition. In fact, rapid weight loss may give rise to some complications which may aggravate the condition further.
Thyroid glands are not always at fault: Many people associate thyroid problems with some abnormalities or improper functioning of the thyroid glands. There is no denying the fact that problems in the thyroid glands often trigger thyroid disorders. However, this is not the only cause. A host of other factors such as stress, medical conditions, certain medications and unhealthy lifestyle habits may be equally responsible for the thyroid problems. In some cases, the body may fail to utilize the thyroid hormones produced by the thyroid glands. In another condition, the thyroid hormone produced is unable to enter the cell (triggered by a problem in the cell receptor). It is important to identify the root cause of the problem rather than generalizing.
People with hypothyroidism do not need to gulp down tons of iodine. Always use the amount recommended by the doctor. Increased intake of iodine supplements (way above the recommended quantity) may result in unnecessary health complications such as Wolff-Chaikoff effect.
Many health organizations or individuals may promise instant relief and cure. They may lure you with some irresistible offers. However, it will be foolish on your part to fall for such claims. Always seek the help of experienced and genuine health professionals.

Thyroid - 5 Common Mistakes That Most People Do!

Your thyroid is a small, butterfly-shaped gland situated at the base of the front of your neck, just below your adam's apple. Hormones produced by the thyroid gland do everything from maintaining your heart rate to regulating your body temperature to controlling your body weight. 
Millions of people worldwide suffer from thyroid dysfunction and several don't know about it. This is primarily because people don't tend to link the common symptoms first with a thyroid disease. Some people suffer from mood swings, trouble with memory, weight gain or fatigue, all of which they look upon individually as a problem and hence not piecing together the puzzle of their real medical condition. Here are a few insights that'll help you cope:
How does the thyroid gland work?
About 85% of the hormone produced by our thyroid gland is t4, which is an inactive form of the hormone. After t4 is made, a small amount of is converted into t3, which is the active form of thyroid hormone. T3 is then converted to free t3 or reverse t3. It is the free t3 that forms the base of thyroid functions. 
What is hypothyroidism?
Hypothyroidism, or an underactive thyroid, accounts for 90% of all thyroid imbalances. The signs and symptoms of hypothyroidism develop slowly, often over a number of years, which is why it is often missed from regular treatment charts. For instance, fatigue and weight gain are often attributed to stress, lifestyle changes and natural ageing process. But as time goes by, some of the symptoms show a higher level of manifestation like muscle weakness, elevated blood cholesterol, thinning hair, puffy face, hoarse voice and slowed heart rate. 
If left untreated, hypothyroidism may lead to goiter (enlarged thyroid), increased memory problems, low blood pressure, decreased breathing and in extreme cases, unresponsiveness and coma. 
This disease may also occur in newborns, infants and children. Symptoms include excessive sleepiness, poor muscle tone and constipation. It is important to diagnose and treat it early, as in severe cases it may lead to mental and / or physical retardation. In children and teens, it can result in stunted growth, and delayed puberty.
What is hyperthyroidism?
It's the opposite of hypothyroidism, which means in this case the thyroid overproduces hormones. Common symptoms include lack of sleep, weakness, irregular heartbeat, elevated blood pressure and hand tremors. While genetics are partially responsible for it, it is also triggered by autoimmune disorder. Hyperthyroidism can be treated with medication, radioactive iodine (not the first or best choice as it harms white cells too) and surgery. Keeping a focus on your calcium and sodium intake is crucial to curb the disorder.
Treatments: 
Conventional treatments rely mainly on drugs and surgery. Alternative treatments involve diet and lifestyle changes. Taking multivitamins, going gluten free, getting a good night sleep, and reducing stress is all said to help heal your thyroid gradually.

Thyroid Dysfunction and Treatment

Thyroid disorders are conditions that affect the thyroid gland, which is a butterfly-shaped gland in front of the neck. There are specific kinds of thyroid disorders that include:

Hypothyroidism
Hyperthyroidism
Goiter
Thyroid Nodules
Thyroid Cancer
Epidemiology, Incidence, and Prevalence
It has been estimated that about 42 million people in India suffer from thyroid diseases.

Hypothyroidism

Hypothyroidism occurs when the thyroid gland produces an insufficient amount of thyroid hormone. It can develop from problems within the thyroid gland, pituitary gland, or hypothalamus. 

Symptoms of hypothyroidism can include:

Fatigue
Poor concentration or feeling mentally "foggy"
Dry skin
Constipation
Feeling cold
Fluid retention
Muscle and joint aches
Depression
Prolonged or excessive menstrual bleeding in women
Common Causes of Hypothyroidism

Hashimoto's thyroiditis (an autoimmune condition that causes inflammation of the thyroid gland)
Thyroid hormone resistance
Other types involving inflammation of the thyroid, such as acute thyroiditis and postpartum thyroiditis
Hyperthyroidism

Hyperthyroidism refers to the excessive production of thyroid hormone, a less common condition than hypothyroidism. Symptoms of hyperthyroidism are usually related to increased metabolism. In mild cases, there may not be apparent symptoms.

Signs and symptoms of hyperthyroidism can include:

Tremors
Nervousness
Fast heart rate
Fatigue
Intolerance for heat
Increase in bowel movements
Increased sweating 
Concentration problems
Unintentional weight loss
Common causes of hyperthyroidism

Graves' disease
Toxic multinodular goiter
Thyroid nodules that overexpress thyroid hormone (known as "hot" nodules) 
Abnormal secretion of TSH
Thyroiditis (inflammation of the thyroid gland)
Excessive iodine intake
Goiter: A goiter is an enlargement of the thyroid gland, regardless of cause. A goiter may be associated with hypothyroidism, hyperthyroidism, or a normal thyroid function. 

Thyroid Nodules: Nodules are lumps or abnormal masses in the thyroid. Nodules can be caused by benign cysts, benign tumors, or less commonly, by cancers of the thyroid. If nodules are excessively large, they may cause symptoms related to compression of nearby structures. 

Thyroid Cancer: Thyroid cancer is more common among adult women than men or youth. About 2/3rd of cases occur in people under age 55. There are different kinds of thyroid cancers depending upon the specific cell type within the thyroid that has become cancerous. Most cases of thyroid cancer have a good prognosis and high survival rates, especially when diagnosed in its early stages.

Investigations

Blood tests are done to measure levels of thyroid hormones. Blood tests are also done to identify antibodies against thyroid tissue, such as titers of antithyroglobulin, antithyroperoxidase, or TSH receptor-stimulating antibodies.

Treatment

Thyroid disorders can be treated with medications or, in some cases, surgery. The treatment will depend on the particular disease of the thyroid.Medications can be given to replace the missing thyroid hormone in hypothyroidism. Synthetic thyroid hormone is given in pill form by mouth. When hyperthyroidism is present, medications can be used to decrease the production of thyroid hormone or prevent its release from the gland. 

Thyroid Disorder - What All Should You Know 

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