Hypothyroidism is a condition in which the thyroid gland is not producing the thyroid hormones adequately. This is a fairly common condition.

What is thyroid gland?

The thyroid gland is a small butterfly-shaped gland located just below Adam s apple. It encircles the windpipe or the trachea. It is about 4 cms in height and weighs about 18 gms. This gland is responsible for the secretion of thyroid hormones. Hormones are chemicals produced by special glands like thyroid, adrenals, ovaries etc. They act as messengers and are carried by the blood to the various target organs.

What are the hormones produced by thyroid gland and what do they do?

The thyroid hormones are of two types   T3 (Tri iodo thyronine) and T4 (Thyroxine). These hormones are mainly responsible for the body s metabolism - a process in which food is converted into energy in the cells. They influence growth and development and regulate various bodily functions which are mentioned below:

Heartbeat
Body temperature
Breathing
Body weight
Metabolism of fat
Menstrual cycles in females
Functioning of Nervous system
Digestion
Burning calories etc.
What is Hypothyroidism?

Inadequate production of hormones by the thyroid gland is termed as hypothyroidism. This is also called Underactive thyroid state. Hypothyroidism can make the body s development to slow down and reduces metabolism rates.

What are the causes of Hypothyroidism?

Hypothyroidism can be caused by a number of factors:

Hashimoto's thyroiditis: This is the commonest cause. This is an autoimmune disorder (normally body s defence system fight against external infections. In autoimmune disorder the defence system attacks the healthy cells of the body by mistake). In Hashimoto s thyroiditis the immune system/defence system produces antibodies that attack the thyroid gland and destroy it.
Iodine deficiency in diet. For the production of thyroid hormones iodine is very important. The body does not produce iodine normally, so it needs to be supplemented from outside. Iodine is mainly present in the food we eat. It is mainly present in shellfish, salt-water fish, eggs, dairy products. If a person does not eat iodine rich foods, he may end up with iodine deficiency leading to hypothyroidism. Currently, this causative factor is on the decline due to government initiative of table salt with iodine.
Surgery: Surgery to remove thyroid gland (for e.g. thyroid cancer treatment, overactive thyroid etc.)
Radiation to the neck (to treat cancer in the neck area): The thyroid gland cells are damaged due to the radiation.
Treatment with radioactive iodine: This treatment is used for managing hyperthyroidism/overactive thyroid, where the thyroid gland produces excessive thyroid hormones. One of the treatment modalities is by radioactive iodine. Sometimes this radiotherapy destroys normal functioning cells which lead to hypothyroidism.
Certain medicines: Certain medicines used to treat heart conditions, cancer, psychiatric conditions etc.   for e.g. amiodarone, lithium, interleukin-2, interferon-alpha.
Pregnancy: Pregnancy (the reason is unclear but it has been noticed that the thyroid may get inflamed after delivery   this is called Postpartum thyroiditis.
Damage to the pituitary gland: Pituitary gland is a gland which is present in the brain. It produces a hormone called TSH (Thyroxine-Stimulating hormone).The TSH tells the thyroid gland how much thyroid hormone it should make. If the levels of thyroid hormone in the blood are low, then the TSH will stimulate the thyroid gland to produce more Thyroid hormone.
Hypothalamus disorders: This is an organ in the brain. This produces a hormone called TRH (Thyrotropin Releasing Hormone) which acts on the Pituitary gland to secrete TSH. So any disorder of Pituitary gland will indirectly effect the production and secretion of Thyroid hormones. These are very rare disorders.
Congenital thyroid defects: Some babies are born with thyroid problems. This is due to the thyroid not being developed normally during pregnancy. Sometimes the thyroid gland does not function normal. This can be identified by screening for thyroid disorders in the first week after delivery. This is usually by a blood test using a small drop of blood from the baby s heel.
What are the different types of hypothyroidism?

One classification is based on whether the defect is with the thyroid gland or not:

Primary hypothyroidism: The problem is in the thyroid gland itself and thus there is reduced production /secretion of thyroid hormones.
Secondary hypothyroidism: Here the problem is with the Pituitary gland or the Hypothalamus. This results in abnormal production of TSH or TRH, which indirectly leads to less production and secretion of thyroid hormones.
Another classification is based on the symptoms and levels of the thyroid hormones and TSH:

Overt hypothyroidism: Here the patient is having the symptoms. Further the T3/T4 are low and TSH is high
Subclinical hypothyroidism: Here patient may or may not have symptoms. The T3/T4 levels are normal but TSH is high. In this situation the patient is at an increased risk of developing overt hypothyroidism in the future especially if he has Thyroid peroxidase antibodies on testing.
Who are at risk of developing Hypothyroidism?

Women have a higher risk of suffering from hypothyroidism than men.
Older people are at increased risk.
People suffering from other autoimmune diseases like Coeliac disease, Type-1 Diabetes Mellitus, Vitiligo, Pernicious anemia, Multiple sclerosis, Rheumatoid arthritis, Addison s disease etc.
People with psychiatric conditions such as bipolar disorder
People with Chromosomal abnormalities like Down syndrome, Turners syndrome also have a high risk of suffering from hypothyroidism.
What are the symptoms of hypothyroidism?

Symptoms vary from person to person. They may also mimic other conditions and hence be difficult to diagnose. Symptoms may also develop very slowly over a span of moths-years. Some of the characteristic symptoms of this disease are:

Depression
Constipation
Hair loss
Dry hair
Dryness of the skin
Tiredness
Body pains
Fluid retention in the body
Irregular menstrual cycle
Increased sensitivity to cold
Reduced heart rate
Increase in size of the thyroid gland   called Goitre. This is due to constant stimulation of the thyroid gland by TSH.
Weight gain
Carpal tunnel syndrome
Hoarse voice
Infertility
Loss of libido/sex drive
Confusion or memory problems especially in the elderly
What are the symptoms to look for in a baby if you suspect hypothyroidism?

Infants suffering from congenital hypothyroidism may show no symptoms or exhibit signs of excessive drowsiness, cold hands, cold feet, constipation, hoarse cry, poor growth or absent growth, poor appetite, bloating of abdomen, puffiness of face, swollen tongue, persistent jaundice.

How to diagnose hypothyroidism?

Blood tests:

TSH: This hormone is made in the pituitary gland and it stimulates the thyroid gland to produce thyroxine. If the thyroxine levels are low in the blood, the pituitary gland produces and secretes more TSH into the blood to act on the thyroid gland to produce more thyroxine. A raised TSH level indicates hypothyroidism. Other tests are not usually necessary unless a rare cause of hypothyroidism.
T4: A low level of thyroxine indicates hypothyroidism.
T3: these levels are generally not needed to diagnose hypothyroidism
Anti-Thyroid peroxidase antibodies (anti-TPO antibodies) or Anti- thyroglobulin antibodies are present in 90-95% of patient with autoimmune thyroiditis.
Other blood tests include Creatinine Kinase, Serum Lipids, Complete blood picture etc.
Ultrasound of the neck is done if the patient presents with a thyroid swelling.
What is the treatment of hypothyroidism?

Overt hypothyroidism is treated by synthetic Thyroxin hormone which should be taken every day on an empty stomach at least 30   45 minutes before breakfast. The treatment is continued for the rest of the patient s life. Regular thyroid function tests are done once every 8 weeks-12 weeks to adjust the dose of the thyroxine in the initial period of diagnosis. Once the thyroxine dose is stabilised, the tests can be done even once a year. This treatment is quite effective.

Sub-clinical hypothyroidism is only treated if the patient is a woman and is contemplating pregnancy, in patients with symptoms or if the TSH is quite high.

What are the side-effects of thyroxine medication?

There are few side effects if any. Most people tolerate these medications quite well. An important consideration before starting medication is to check if the patient has chest pain/angina. These people are started on the least available dose. If these patients are started on a higher dose they notice a worsening of their angina pains.

Side effects mainly occur if the thyroxine dose is high which leads to hyperthyroidism. The symptoms of this could be palpitations 9increased heart beat), weight loss, profuse sweating, anxiety, irritability etc.

There are some tablets which increase with thyroxine tablets. These include carbamazepine, iron supplements, calcium supplements, rifampicin, phenytoin, warfarin etc.

What are the complications of hypothyroidism?

If untreated hypothyroidism can lead to:

heart problems like heart attack due to increased levels of bad cholesterol like LDL, or heart failure due to fluid retention
obesity
infertility
joint pains
depression
A pregnant woman with hypothyroidism is at increased risk of giving birth to a baby with congenital hypothyroidism, also known as cretinism. Further, the woman may have pregnancy related complications like pre-eclampsia, premature delivery, low birth weight baby, anemia, post-partum haemorrhage (bleeding after delivery) etc.
Myxoedema is another complication where the patient has extremely low levels of thyroid hormone. The body temperature drops drastically making the person lose consciousness or go into a coma.
References:

2013 ETA Guideline: Management of Subclinical Hypothyroidism; European Thyroid Association (Nov 2013)
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee; British Thyroid Association (2015)
The diagnosis and management of primary hypothyroidism; Royal College of Physicians and others (June 2011)
Suh S, Kim DK; Subclinical Hypothyroidism and Cardiovascular Disease. Endocrinology Metabolism (Seoul). 2015 Aug 4.
UK Guidelines for the Use of Thyroid Function Tests; British Thyroid Association (2006)
Gaitonde DY, Rowley KD, Sweeney LB; Hypothyroidism: an update. American Family Physician. 2012 Aug 1 86(3):244-51.
Bindra A, Braunstein GD; Thyroiditis. American Family Physician. 2006 May 15 73(10):1769-76.
Wilson GR, Curry RW Jr; Subclinical thyroid disease. American Family Physician. 2005 Oct 15 72(8):1517-24.
British National Formulary; NICE Evidence Services (UK access only)
Baumgartner C, Blum MR, Rodondi N; Subclinical hypothyroidism: summary of evidence in 2014. Swiss Medical Weekly. 2014 Dec 23 144:w14058. doi: 10.4414/smw.2014.14058. eCollection 2014.

Know Everything About Hypothyroidism

Most of Almost every one of us dreams of a flawless skin. But, your beauty gets a patch of ugliness with the presence of unwanted moles on your skin. Moles develop from cells called melanocytes, which produce pigment melanin that gives skin its color. It is for this reason that the moles are darker than the other parts of the skin. They are usually caused due to hormonal changes.

Here are some common causes behind moles:

Teenage: It is the stage that sees a lot of hormonal changes and imbalances. This increases the chance of developing moles.
Pregnancy: It is that period when a woman s body goes through a hell lot of changes. It doesn t give rise to more moles but it is responsible for darkening of the existing ones.
Sunlight: Exposure to sunlight for a prolonged period of time may lead to the formation of moles. These can worsen later by taking the shape of melanoma, or skin cancer.
Genetics: Researchers believe that genes are responsible for having moles on the body or face.
Types of Moles
It is difficult to identify the various types of moles. They almost look the same. But, on closer scrutiny, you will see the differences. Here are the most common ones:

Dermal melanocytic naevi: They protrude from the skin. They have a pale hue. They may have hair on them as well.
Junctional melanocytic naevi: They are either flat or round. They are deep brown or black in colour.
Compound melanocytic naevi: They protrude from skin. They are light brown in colour.
Blue naevi: They are dark blue in colour.
Halo naevi: The moles have a pale circular ring around it.
Home remedies to get rid of moles
Here are some common home-based remedies to treat moles:

Apple Cider Vinegar: It is a strong natural acid. It burns the area and the mole falls off. But, you need to be anti-allergic to the acid. Dip a cotton ball in the acid and apply on the affected part. You will see results in 10 days time.
Baking soda and Castor oil: The mixture of baking soda and castor oil makes a slow but effective solution for treatment of moles. It also prevents the scars. Castor oil has the ability to disperse any growth of pathogens.
Flaxseed oil, Ground Flaxseeds and Honey: This is an effective remedy for moles that are raised from the skin. It causes loosening of the edges of the mole. Gradually, the mole falls off due to its application.

Moles - Know The Common Types!

Allergies are caused by unnatural reactions between your body's immune system and foreign substances, which have gained access into the body. When these substances, known as allergens, enter your body, your immune system produces antibodies, which are responsible for warding off unwanted substances like harmful viruses or diseases and helping in the body's overall resistance.

The main cause of allergy is the uncontrolled reaction between the immune system's antibodies and harmless allergens. Allergic reactions are triggered when antibodies, like histamine, come into contact with particular types of allergens. These may include:

    Certain eatables: Peanuts or sea food
    Medications: Penicillin or penicillin-based antibiotics
    Airborne allergens: Pollen, mold, or dust mites
    Insect stings: Bee stings or scorpion stings
    Latex: Latex or other substances, which are responsible for causing allergic skin reactions

Symptoms of allergies depend upon a wide range of factors, which are subjective and vary from person to person and from allergen to allergen. Depending upon the type of allergen involved and the nature of the allergy, symptoms may include any of the following:

    Facial swelling
    Wheezing
    Severe itching
    Swollen or red and watery eyes
    Hives
    Flaky skin which can peel off

These symptoms are common in mild to moderate allergies, such as atopic dermatitis, hay fever, drug or food allergies. There are certain rare cases (say, scorpion stings), however, in which the allergic reaction turns out to be potentially life-threatening. This type of reaction is known as anaphylaxis. Here are its signs and symptoms:

    Nausea and vomiting
    Loss of consciousness
    Skin rashes
    Intense shortness of breath
    Lightheadedness

Homeopathy effectively deals with any sort of allergy by taking into account individualistic symptoms and thus nipping the root cause in the bud. Natrum Mur, Urtica Urens, Sulphur and Natrum Carb, among others, are very effective medicines against allergies. But these must be taken after due discussion with the doctor as they check out the symptoms and then prescribe the medicine basis that.

Allergies: Causes, Symptoms and How Homeopathy Deals With It Efectively

A common form of skin inflammation brought about by the fungal infection is called as Athlete's Foot and is most commonly seen among the athletes. In medical terms, this condition is called "tinea pedis". This generally starts in between the toes and gradually moves towards the toe nails, if left untreated. In the later stages, this infection has the tendency to move towards the palm region of the hands and other body surfaces, if left unchecked. Most often, this condition is referred to as the ringworm of the moccasin feet. 

Statistics have shown that about 15% of the population is affected by this condition. It is important to note that men have a higher chance of contracting this contagious condition than women. Young adults or old children are most likely to take the hit for this condition.

After a serious research, the National Health Service has come out with the finding that, Athlete's foot can be transmitted from one person to another either by direct or indirect contact. Any environment that is warm and moist serves as the perfect breeding place for the fungal species to cause this condition.

Getting them treated before the condition spreads to other parts of the body is a very important step that has to be taken by the person who has been diagnosed with this disease. Instead of worrying about the condition after it has set in, a few remedial precautions can be taken to prevent the onset of this disease. 

Some preventive measures are:

1.  Clean shoes and socks: The socks have to be changed at least twice a day and these must be able to absorb the sweat from the feet.

2.  Using a medicated powder: Normal talcum powder or an anti-fungal powder can be applied to the skin where the irritation prevails and this kills the fungi that might form on the surface.

3. Precaution after swimming and going for walk: The region between the toes has to be wiped clean after swimming, bathing or going for a long walk. The basic idea is to remove the excessive moisture from the skin.

4.  Using socks and sandals: The sandals must allow some breathing space for the skin on the legs and when at home, socks without shoes can be worn. 

Preventive measures help a great deal in avoiding the complications that arise out of this Athlete's foot.

Athlete's Foot - How To Prevent It?

When the natural moisture content of your skin begins to dry up, you experience dry skin. Although it is a temporary skin condition which occurs mainly during the winter or in a generally dry climate, for some people, it could be a problem for a lifetime.

Naturally dry skin tendencies v/s drying of other skin types
Naturally, the water content of a healthy skin is around 10 to 20 percent. This natural moisture level can dwindle due to many factors and the skin may show signs of drying. Thus you may end up getting dry, flaky, itchy and lifeless skin. People with naturally dry skin experience 75 percent more water loss than normal skin. Since the skin loses water and sebum (the oil secretion from the sebaceous glands within the skin), the topmost layer of the skin begins to dry. As a result, the top layer starts peeling away. These skin peels are called flakes.

Causes

You can experience dry skin due to excessively cold weather, which in most cases is accompanied by a lack of humidity.
Again, if your skin is exposed to too much heat or skin drying conditions like sauna baths or prolonged hot showers, you experience dry skin.
Applying skin cleansing materials or chemicals can also make the skin dry.
Some internal disorders like illness or infection can make your skin dry.
Treatment
When you have a perennially dry skin, you should moisturize it daily to keep it hydrated. You should consult a dermatologist for picking out the right skin cream for your skin. The appropriate moisturizer, if you have very dry skin should be oil or petroleum based. When you purchase the prescribed moisturizer or lotion, make sure you buy something which contains vitamin E, Shea Butter and Avocado Oil. Since these moisturizing agents aren t water based , they can lock in the skin moisturizer effectively.

Advantages of moisturising regularly

Dry skin is prone to wrinkle formation   When you moisturize daily, the collagen levels of your skin are restored, which can then effectively fight wrinkling and aging of your skin.
Prevents flakiness   Since the upper layer of your skin starts peeling off, your skin may appear dull, lifeless and flaky. The condition worsens when there is a cold weather outside. Moisturizing your skin daily will make your skin get a natural glow and stop flaking form occurring in the first place.
Reduces itchiness: Moreover, daily moisturizing will make your skin less itchy.
Moisturising reduces the negative effects of makeup: Not moisturizing dry skin will make it look less hydrated. Applying makeup on your dry skin directly is the worst thing you can do. This may spoil your makeup and make it look creasy and broken. Thus, you should keep your skin hydrated by applying moisturiser regularly.

Flaky Skin - Why You Should Moisturize it Daily?

5 horrible things you do to your hair everyday

Hair today, gone tomorrow. That might be your condition if you are not taking care of your hair properly. There are a lot of things you do almost daily that are adversely impacting your hair health. You might not even be aware of the damage you are doing to your tresses by indulging these activities. Read on to find out about the 5 worst things you do to your hair on a daily basis.

1. Excessive hair brushing: Here’s why brushing your hair excessively is bad for your hair: it causes breakage and strips your hair of its natural nourishing oils. To avoid this, try limiting the use of your hair brush to about just two times in a day. Brushing right after you wake up is a good idea, as it helps in distributing the oils produced by your scalp down your hair shaft, which act as a natural conditioner for your hair.

2. Tying your hair in a ponytail everyday: If you tie your hair in a ponytail everyday then chances are you are applying consistent pressure to on the same hair shafts, resulting in brittle and weaker hair. In fact, doing so continuously can even retard hair growth. Try to leave it open as much as you can, but if you absolutely must tie a pony tail, then tie a loose one. Maybe even use booby pins to keep your hair in place instead of scrunchies. Alternating between high and low ponytails helps too.

3. Using a pre-used hairbrush: Your hairbrush contains a lot of germs, which can severely damage your hair. Using an unclean brush is one of the main reasons of damage hair, as these brushes contain dirt gathered from your hair which you’re giving back to your hair by using. It’s best to clean it once in a while to maintain proper hair health. The same holds true for other styling agents such as combs, curlers, rollers, straighteners etc.

4. Delaying a hair cut: Most of us are guilty of this crime. What with your jam-packed schedule and work overload, you often ignore that much needed trip to the salon. Prolonging a haircut is never a good idea as it can lead to a bad case of split ends, which can result in hair that tangles a lot and causes hair fall. Regular trimming sessions, once every 6 weeks, are a must.

5. Shampooing in excess: Some of you prefer your scalp to be squeaky clean every single day, believing that daily dust and pollution require you to indulge in this unhealthy habit. Well, it’s best to stop right now as you’re harming your hair by shampooing daily. Daily shampoos can completely strip your hair of its natural oils, causing your scalp to become dry, leaving your hair with a dry, messy and rough feel. However. Delaying hair wash is not good either. It is best to shampoo whenever your hair feels greasy and dirty.

Avoid doing these to your hair, and let your tresses breathe so that they look healthy and shine with a natural glow.



5 Worst Things You Should Stop Doing to Your Hair!

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