Women are not really sure about frozen embryos  ability to result in pregnancy. Ironically, the success of Frozen Embryo Transfer has dramatically improved over the last few years. In the days gone by, the chance of women getting pregnant through the use of frozen embryos seemed to be on the lower side compared to that from the transfer of fresh embryos. Recent data related to this suggests that this is no longer the case.

Reasons behind the low success rate of frozen embryo transfer in the past
Previously during the frozen embryo transfer process, the embryos which had to get frozen were the ones that did not get chosen for the fresh embryo transfer initially. The reason being that the embryologist had gone ahead to choose the best possible embryos for getting them transferred initially. As far as the fresh embryo transfer is concerned, quality of embryo has got a major effect on the chance of a woman getting pregnant. On the other hand, if quality of embryos frozen is not good, the rate of survival after it gets thawed along with the rate of pregnancy would be on the lower side.

The second important reason is the amount of embryos that got transferred. Let us consider a couple who produce four very good quality embryos. Two of them are transferred during fresh In Vitro Fertilization Process and the remaining two are frozen. This leads to pregnancy and the woman gives birth to a baby. Later on, the couple once again decides to go for pregnancy by using the frozen embryos. Though only one embryo survives after getting thawed. The frozen embryo transfer is that of a single embryo. The success rate of a frozen embryo transfer through a single embryo is always going to be on the lower side than what it will be when multiple embryo transfer is involved.

Finally the method of freezing embryos has seen a sea change quite a number of years ago. Nowadays the freezing of embryos takes place by a fast method, known as vitrification. This process has got a much better survival rate when embryos get thawed along with good rates of pregnancy when those particular embryos are transferred in a much better manner.

Studies about high success rate of frozen embryo transfer
There have been studies performed in women, who have had quite a vigorous stimulation of their ovaries and were considered to be at high risk for Ovarian Hyperstimulation Syndrome. The physicians took the decision of skipping the process of embryo transfer and instead go ahead to freeze all the embryos for use at a later stage.

This tends to significantly decrease the risk of having serious Ovarian Hyperstimulation Syndrome along with decrease in complications. Other cases involved, physicians deciding to move on with a fresh embryo transfer depite the risk of Ovarian Hyperstimulation Syndrome. In both the scenarios the couples have quite a large number of embryos and the embryos selected for transfer were the best embryos.

The studies have shown no difference in the rates of pregnancy between fresh or frozen embryos or for that matter higher rate of pregnancy with frozen embryos.

How Successful Is Frozen Embryo Transfer?

Sleep is one such time when people usually are expected to lie down still and get rest. However, we have all heard of sleepwalking, a condition where a person walks during the sleep. Though it may sound strange, there is a deeper explanation for it both from a causative point of view and from managing it.

Things you should know?

Sleepwalking happens when a person moves back from a deep sleep to a light sleep or awakening state.
The person who is sleepwalking is usually not aware of it.
Activities may range from simply getting up and sitting up in bed to walking around the room. They could also open the door and walk out to the neighbourhood. Moving furniture, changing dresses or driving a car, may also be some of the actions Most of these activities happens completely without their knowledge.
Mostly happens in children up to the age of 12, but can be seen in adults also, where it assumes a more severe form.
The person who is sleepwalking has a fixed stare with glassy eyes. They may appear dazed and lost when they are awakened.
They may not respond when they are actually sleepwalking, or respond very slowly
They can be brought back to bed and put back to sleep without being disturbed. Most children would go back to sleeping when this is done
Though the parents can be very worried when they see children sleepwalking, reassurance is required, as it usually disappears as they cross teenage.
There could be chances of small injury like tripping or fall during the sleepwalking episode
Sleepwalkers may be more restless compared to other children during their waking hours
Bedwetting is also quite common in children who sleepwalk
Causes

Inappropriate sleep pattern with lack of sleep for prolonged periods is one of the main reasons for sleepwalking
Stress
Excessive drinking
Medical conditions like heart rhythm problems, acidity, gastric reflux, and seizures
Psychiatric conditions like panic attacks and post-traumatic stress disorder can also lead to sleepwalking
Management

For a parent to see their child walking around in their sleep can be quite disturbing.
Reassurance is required stating that it is just a temporary phase and will not stay beyond the teenage years
Most people do not require any intervention unless accompanied by severe symptoms like going out of the house or driving
Once established, it is advisable to avoid by not drinking too much alcohol, avoiding stress and anxiety and taking precautions like extra-secure locks to prevent sleepwalking and/or other side effects.

Sleepwalking - 11 Things You Must Know!

Parkinson s disease usually develops at a very slow rate and the early signs of this disease often go unnoticed. As the condition progresses, the symptoms become more prominent. Parkinson s disease affects the nervous system and cannot be completely cured. However, with proper treatment, its rate of progression can be slowed and this condition can be managed. The earlier a diagnosis is made, the more effective treatment will be. Thus, it is important to be able to recognize the signs the symptoms of this disease.

The signs and symptoms of Parkinson s disease vary from person to person. In most cases, symptoms begin on one side of the body and are worse on that side even after it begins to be noticed on the other side. These symptoms can include:

Tremors
Involuntary shaking of a part of the body is usually the first sign of Parkinson s the hands are most affected by this symptom. These tremors can be felt while performing an activity or even when the hand is at rest. In some cases, it can even keep a person from performing normal tasks such as writing. Tremors caused by Parkinson s can also take the form of an uncontrollable back and forth rubbing movement between the thumb and forefinger.

Slow Movements
This is also known as bradykinesia. As the disease progresses, it can slow down movement and reduce the person s ability to move. Simple tasks such as walking can become more difficult and take much longer. The person s steps may become shorter and they may also drag their feet as they walk. Parkinson s patients may also find it difficult to get in and out of chairs.

Rigidity
Parkinson s can make muscles stiff and difficult to move. This can affect the muscles of any part of the body. This rigidity can limit the person s range of movement and make moving the affected muscles very painful.

Loss of certain movements
In addition to muscle rigidity, the person may not be able to make certain movements that we take for granted. For example, he or she may not be able to blink or smile. Swinging the arms while walking may also become more difficult.

Changes to speech
Parkinson s can make a person speak slower and reduce his or her natural volume. The person s speech may also sound slurred. In addition, they may find it difficult to speak with inflections due to which their speech may appear to be monotonic.

Imbalance
Parkinson s may affect a person s posture and balance. In many cases, Parkinson s patients develop a stoop. The loss of balance can make climbing stairs difficult and cause them to fall easily.

Parkinson's Disease - Signs And Symptoms You Should Know About It!

What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

Trigeminal neuralgia is specified by the condition of a chronic pain that influences the trigeminal nerve. This nerve transfers sensation from one s face to his/her brain. If a person is suffering from trigeminal neuralgia, then a gentle stimulation of face (sourced from brushing teeth or applying makeup) might generate a fright of agonizing pain. The affected person might experience short and mild attacks initially. However, the trigeminal neuralgia might progress and generate more-frequently and longer attack of severely critical pain. Women get affected by this situation more than men get and it is more prominently occur in individuals older than 50 years.

Trigeminal neuralgia does not mandatorily mean that you need to experience a lifelong pain. Various types of treatment alternatives are available and so doctors can usually handle the particular condition effectively by taking help of injections, medications or surgery. Various types of triggers might cause the pain regarding trigeminal neuralgia, such as eating, drinking, shaving, brushing teeth, touching face, smiling, washing face etc.

Symptoms

The symptoms of trigeminal neuralgia might comprise of one or more patterns and some of these are described below:

Sequences of serious, jolting or shooting pain that might generate as an electric shock
Spontaneous pain attacks or attacks stimulated by different activities like face touching, speaking, chewing, or brushing teeth. Pain attacks last from a few moments to some minutes.
It is not a comprehensive list because Trigeminal neuralgia hosts various other symptoms as well. If a person feels facial pain, specifically recurring or prolonged pain or if the person does not get relief through the utilization over-the-counter pain relievers, then that person must consult a doctor.
How does Radiofrequency Ablation treat Trigeminal Neuralgia?
Trigeminal Neuralgia is a chronic and painful condition that involves the trigeminal nerve. There are two separate trigeminal nerves on both sides of the face, which carry the sensations like pain from the face to the body. Each nerve has three branches- forehand, midface and chin and trigeminal neuralgia can cause intense pain in any of these areas.

Causes-

This occurs when the trigeminal nerve functioning is disrupted. When the blood vessel/artery and the trigeminal nerve at the base of your brain come in contact, it puts pressure on the nerves and causes pain.
It also occurs as a result of ageing or multiple sclerosis
A disorder that damages the myelin sheath protecting the nerves can trigger pain
Sometimes pain occurs from tumors, which compresses the trigeminal nerves
Surgical strokes, facial trauma or strokes can also be the root cause of excruciating pain
Triggers-

Shaving
Touching your face
Eating and drinking
Putting on makeup
Brushing
Washing your face
Symptoms-
The pain can be mild and for a shorter duration or it can happen frequently for longer durations. Some experience the pain in cycles where it can come and go for days or even for weeks. Gradually the intensity of the pain lessens.

Cure by Radio-frequency Ablation
The treatment of trigeminal neuralgia is often a challenging process in clinical practice. When medicines do not prove as effective, surgery is the desired option.

Procedure-

After applying local anaesthesia, the Pain Specialist carefully inserts a needle through the corner of your mouth to reach the trigeminal nerve
The doctors then wake up the patient after stimulating the nerves and ask them to feel the stimulation at the same place where they undergo pain. This confirms their targeted location
Once you fall asleep again, the Pain Specialist uses radiofrequency heat to injure the nerve enough to create numbness and removes the pain
How Effective is Radio-frequency Ablation?
The pain is cured almost in 98% of the patients. 50% of patients report recurrence of pain after about two years. Hence the procedure can be repeated in the same patient if necessary.

Trigeminal Neuralgia And Radio-Frequency Ablation - What Causes It?

Epilepsy is a brain triggered disorder that can result in the affected person having seizures or convulsions of the body. Such convulsions last about a few minutes and the person undergoing epileptic seizure might be unaware of what s happening to him/her during those brief moments. They may recover and appear disoriented for a few minutes more. 

Epilepsy can t be cured but is treated through medicines called anticonvulsant drugs.

Epilepsy is a neurological disorder brought about due to unusual electrical activity in the brain
The person having the disorder can have episodes of seizures where there can be sudden involuntary movements of the person s whole body and shaking of the arms and legs lasting a few minutes
The condition can occur to anybody irrespective of age but children seem to suffer more from the condition following a head injury or emotional trauma
Electroencephalogram or EEG is the best way for the doctor to understand the exact nature of the disorder and this will help in the treatment.
Treatment through drugs is the most popular way of keeping the convulsions under check
Medically, if the patient goes without seizures for a few years under regular medication then there is every possibility the person may not suffer further convulsions
Apart from medication, dietary regulations have also been adopted by many physicians to treat the condition. Low carb and high protein items are advised as a way to reduce/stop the epileptic seizures
In some cases, the doctor might decide to conduct a surgery to remove the aberrant part of the brain to treat the individual for epilepsy
People with epilepsy have to take a lot of precautions in their daily routines to avoid getting seriously injured if they were to suffer a sudden attack of seizures
Driving and swimming are to be avoided by them
People standing around can help reduce the suffering by turning the person over to one side and offering a support to the head. Care can also be taken to remove any object that can cause injury to the person while having the convulsions.
Some doctors study the pattern of the seizures occurring and help in regulating them in such a manner that the person gets the convulsions only in the nights while asleep
This can limit the damage done to the person and can also help the person in going about normal routines
Parents must inform the school authorities if their children suffers from epilepsy so that they can provide first aid to such students immediately if episodes occur in school
Epilepsy is a brain-related disorder that can cause the person to go through involuntary shaking of the body and the limbs. It is usually treated with drugs.

Epilepsy - Common Facts About It!

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