Thyroid disorders are conditions that affect the thyroid gland, which is a butterfly-shaped gland in front of the neck. There are specific kinds of thyroid disorders that include:

Hypothyroidism
Hyperthyroidism
Goiter
Thyroid Nodules
Thyroid Cancer
Epidemiology, Incidence, and Prevalence
It has been estimated that about 42 million people in India suffer from thyroid diseases.

Hypothyroidism

Hypothyroidism occurs when the thyroid gland produces an insufficient amount of thyroid hormone. It can develop from problems within the thyroid gland, pituitary gland, or hypothalamus. 

Symptoms of hypothyroidism can include:

Fatigue
Poor concentration or feeling mentally "foggy"
Dry skin
Constipation
Feeling cold
Fluid retention
Muscle and joint aches
Depression
Prolonged or excessive menstrual bleeding in women
Common Causes of Hypothyroidism

Hashimoto's thyroiditis (an autoimmune condition that causes inflammation of the thyroid gland)
Thyroid hormone resistance
Other types involving inflammation of the thyroid, such as acute thyroiditis and postpartum thyroiditis
Hyperthyroidism

Hyperthyroidism refers to the excessive production of thyroid hormone, a less common condition than hypothyroidism. Symptoms of hyperthyroidism are usually related to increased metabolism. In mild cases, there may not be apparent symptoms.

Signs and symptoms of hyperthyroidism can include:

Tremors
Nervousness
Fast heart rate
Fatigue
Intolerance for heat
Increase in bowel movements
Increased sweating 
Concentration problems
Unintentional weight loss
Common causes of hyperthyroidism

Graves' disease
Toxic multinodular goiter
Thyroid nodules that overexpress thyroid hormone (known as "hot" nodules) 
Abnormal secretion of TSH
Thyroiditis (inflammation of the thyroid gland)
Excessive iodine intake
Goiter: A goiter is an enlargement of the thyroid gland, regardless of cause. A goiter may be associated with hypothyroidism, hyperthyroidism, or a normal thyroid function. 

Thyroid Nodules: Nodules are lumps or abnormal masses in the thyroid. Nodules can be caused by benign cysts, benign tumors, or less commonly, by cancers of the thyroid. If nodules are excessively large, they may cause symptoms related to compression of nearby structures. 

Thyroid Cancer: Thyroid cancer is more common among adult women than men or youth. About 2/3rd of cases occur in people under age 55. There are different kinds of thyroid cancers depending upon the specific cell type within the thyroid that has become cancerous. Most cases of thyroid cancer have a good prognosis and high survival rates, especially when diagnosed in its early stages.

Investigations

Blood tests are done to measure levels of thyroid hormones. Blood tests are also done to identify antibodies against thyroid tissue, such as titers of antithyroglobulin, antithyroperoxidase, or TSH receptor-stimulating antibodies.

Treatment

Thyroid disorders can be treated with medications or, in some cases, surgery. The treatment will depend on the particular disease of the thyroid.Medications can be given to replace the missing thyroid hormone in hypothyroidism. Synthetic thyroid hormone is given in pill form by mouth. When hyperthyroidism is present, medications can be used to decrease the production of thyroid hormone or prevent its release from the gland. 

Thyroid Disorder - What All Should You Know 

When the thyroid gland is affected, leading to the thyroid disorder of an underactive nature, it is termed as hypothyroidism. The thyroid gland which is found in the lower portion of the neck is critical to the proper functioning of the human body s metabolism. In simple words, the thyroid hormone being released by this gland has to travel throughout the body to help in the use of energy gained from the food consumed and to keep the vital parameters such as the heartbeat in the right condition. When some antibodies attack the thyroid gland, and don t permit it to release adequate amounts of hormones into the system, the hypothyroid condition results.

The Causes for Hypothyroidism
An inflammation caused to the thyroid gland can result in this condition. This is an auto-immune disorder, in the sense that some internal factors can trigger this inflammation. Medically, the inflammation is termed  thyroiditis . There are also other factors that can cause hypothyroidism. These include radiation therapy. If the therapy has been administered near the neck area and the rays have penetrated to the thyroid gland, the inflammation can occur. Even those suffering from hyperthyroidism, the overactive form of thyroid and given radioactive iodine treatment can suffer from this condition due to the damage caused to the gland. Lastly, certain specific medications, if consumed regularly, can cause the condition.

Particular Sections of the Community at Risk
While there is no strict division among the population on vulnerability to be affected by hypothyroidism, research has indicated that women, and that too older women, may be more at risk. Men may be at a lower risk. Besides this, there are other profiles such as race and age which can also have a bearing on the level of risk. Of particular significance is that people who already suffer from autoimmune disorders are more likely to suffer from hypothyroidism than others.

Symptoms and Diagnosis
Many symptoms might not be unique to the hypothyroidism condition and can be misleading. Constipation, depression, hair loss and fatigue are some of them and an experienced medical practitioner will weigh the other factors, including the profiles explained above to reach the proper conclusion. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised by the physician and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered.

Hypothyroidism Treatment
As mentioned, for the body s metabolism to function normally, it is essential that the thyroid gland releases the thyroid hormone in sufficient quantities. Treatment of hypothyroidism is therefore very essential. The most frequently followed treatment is to prescribe regular intake of the synthetic thyroid hormone called T4. It is usually available in the form of a pill and has to be taken daily. The physician will know the concentration and dosage to be advised. Periodically testing your blood is necessary to monitor the levels.

Inflammation Of The Thyroid Gland - Can It Be Safely Controlled & Treated?

Gestational diabetes, as the name suggests, occurs during gestation or pregnancy when the blood sugar levels exceed the normal level. Gestational diabetes, like other form of diabetes, affects how your body cells use glucose or sugar during pregnancy, and usually disappears after you ve given birth.

Causes and symptoms to look out for!
During gestation, the placenta produces hormones that lead to the accumulation of blood glucose. Under normal condition, the pancreas forms enough insulin to counter the buildup of blood glucose. The level of blood sugar rises when the pancreas fails to produce adequate insulin to manage your blood sugar.

Usually, women with gestational diabetes do not show symptoms. So, the presence of the condition can go unnoticed if they are not diagnosed during routine checkups and screening tests. Nevertheless, if the condition goes out of control, you may feel tired, feel thirsty or hungry, or feel the urge to urinate more often.

What are the risk factors?
About 2-10% of pregnant women are affected by gestational diabetes every year. The following factors are likely to put you at risk of developing gestational diabetes-

Excess body weight- You may develop gestational diabetes if you were overweight or had gained excess weight (BMI equal to or greater than 30) before getting pregnant
Family history- Women who have a family history of diabetes are likely to have gestational diabetes.
Age- Women aged more than 25 years are at a greater risk of developing this condition.
Diabetic history- A slightly raised blood sugar level may act as the precursor to Type-2 diabetes, which in turn increases your chance of getting affected by gestational diabetes.
Previous pregnancy- Women who ve previously given birth to a child weighing more than 4.1 Kg (9 pounds), or have delivered a stillborn child are likely to have gestational diabetes.
What is the treatment for gestational diabetes?
Urine tests are performed to check for ketones. In a non-diabetic person, glucagon, insulin and other hormones avert ketone levels in your blood from soaring up too high. Once you re diagnosed with gestational diabetes, it s important that you consult your doctor for treatment. Uncontrolled blood sugar level can affect you and your baby s health after birth. This condition can be treated in the following ways-

Keep a check on your blood sugar- During pregnancy, your doctor will have you tested for gestational diabetes 4-5times a day to keep a tab on your blood glucose level. For this, a small drop of blood is first drawn from the finger using a needle. The sample of blood is then placed on the test strip inserted into a device called the blood glucose meter to measure and monitor the level of blood sugar in your body.
Medication- Anti-diabetic medications and insulin are prescribed to control the amount of glucose or sugar in the bloodstream. Your doctor may also suggest oral medications like Diabeta and Glynase to manage your blood glucose level.
Healthy diet- Diabetic diet- one that helps control blood sugar levels- is highly prescribed by doctors during pregnancy. Cut down on carbohydrates and sugar, and switch to food items that provide your body sufficient nutrients and calories.
Post treatment the blood sugar levels usually come down to normal within 4-6 weeks of giving birth.

Gestational Diabetes - Know The Risk Factors!

10 symptoms that signal hypothyroidism

When your thyroid malfunctions, you may face difficult health issues. Hypothyroidism leads to excessive weight gain and a lot of other medical ailments. It can be identified by a bunch of symptoms which if present, should not be taken lightly.

1) weight gain - if there is sudden and unexpected weight gain, this is the earliest and definite sign of an underactive thyroid gland. This means that there are strong chances of lowered levels of t3 and t4 hormones in the body, leading to slow metabolism in the body. People suffering from hypothyroidism face increased body weight which becomes difficult to lose despite maintaining healthy diet and exercising rigorously.

2) constant fatigue - if you have slept well the night before, yet you are tired and if this is a regular feature, then chances are that your thyroid gland is underactive. Being low in energy, it gets difficult to complete daily chores or exercise.

3) swelling in the neck - another telltale sign would be goiter - an abnormal swelling in the neck. The thyroid gland mainly concentrates iodine from the blood to create both the thyroid hormones. If there is iodine deficiency in the body, this process gets disrupted resulting in hypothyroidism.

4) hair loss - hypothyroidism causes hormonal imbalance which in turn causes hair loss. If there is sudden, unexplainable hair loss, chances of hypothyroidism are high.

5) imbalance in body temperature - if you are suddenly feeling too cold, it is advised to get your thyroid tests done.

6) brittle nails - if your nails have become brittle, get chipped very easily and look weak, this could be an indication of hypothyroidism.

7) mood changes - the weight gained and the excessive fatigue, both trigger massive mood swings which at times, the person has no control over.

8) constipation - the contractions of the digestive tract get weakened due to low levels of thyroid hormones resulting in constipation. Chronic constipation without any apparent reason could be an indicator of hypothyroidism.

9) irregular menses - if your periods are irregular, do not take it lightly. This could be most likely because of hormonal imbalances which are caused by hypothyroidism.

10) slower heart rate - if your heart beats at less than 60 times per minute, it could be because of the interference by thyroid hormones.

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10 Symptoms That Signal Hypothyroidism. Do You Have Any Of These?

To understand about hypothyroidism, it is essential to first understand the thyroid gland. Thyroid is an endocrine gland situated in the neck and produces the thyroid hormone. This hormone is then carried through the blood to different cells of the body. It helps the organs to function properly maintain the temperature of the body. The two thyroid hormones are Triiodothyronine (T3) and Thyroxine (T4). They regulate protein, fat, carbohydrates and vitamins in the body along with the metabolism. They are also responsible for the proper differentiation and development of cells.

Hypothyroidism or underactive thyroid or low thyroid
This is a condition where the thyroid gland is underactive and produces a low amount of the thyroid hormone. To help the thyroid gland produce the required amount of T3 and T4 hormones, the pituitary gland will make additional thyroid stimulating hormone called TSH. Due to this additional secretion of TSH, one also develops chance of thyroid gland enlargement and in some cases, it can form a goiter. 

The major cause of the low level of thyroid hormones is considered to be iodine deficiency. Hence the addition of iodine to the common salt has always been considered to be a safe method to prevent goiter. There can be several other causes of hypothyroidism such as weak immune system, radiation, surgery, Hashimoto s disease, hormonal changes etc. It can be caused due to pregnancy and is called postpartum thyroiditis.

Symptoms of Hypothyroidism
Whatever be the cause of hypothyroidism, it can show the following mild symptoms:

Increased sense of fatigue or tiredness
Sudden increase in weight with puffiness on the face
Hoarse voice
Muscle weakness with aches, tenderness and stiffness
Joint pain or stiffness
Increased sensitivity towards cold thus causing dry skin
Constipation due to slow metabolism
Decreased heart rate
Elevated blood cholesterol level
Irregular menstrual periods
Decreased concentration and depression too
However, it is important to understand that you may show no symptoms or show some mild symptoms that can be easily confused with some other condition. Hence, a proper diagnosis is a must to confirm hypothyroidism.

Diagnosis of hypothyroidism
The most common tests to determine if you have hypothyroidism are TSH Testing and T4 Testing. In case the low level of TSH is due to a defect in the pituitary gland, your doctor may request for another test called TRH. Also, Anti-thyroid Microsomal Antibodies Testing or thyroid peroxidase test (TPO) helps in identifying if the thyroid gland is damaged.

Treatment of hypothyroidism
Hormone replacement therapy is the best form of treatment available today. It involves the use of synthetic Levothyroxine (T4) or liothyronine (synthetic T3). Before these synthetic hormones were used for several years, however, prescribing thyroxine tablets is the most common mode of treatment and they are generally given for a really long period of time, although the dosage may vary. It is only in rare cases of severe decompensated hypothyroidism that one requires hospitalization.

Apart from the above treatment options, it is best advised to avoid soy products, sugary processed foods and alcohol to keep a check on hypothyroidism. In case you have a concern or query you can always consult an expert & get answers to your questions!

Hypothyroidism - Signs Your Kid Is Suffering From It!

The body has multiple chemicals called hormones, which regulate many of its functions. Increased or decreased levels of these hormones affect various functions including metabolism, growth and sexual functions. Thyroxin produced by the thyroid (situated in the front of the neck) is one such hormone, which has a significant role to play in metabolism.

Graves  disease is one of the main causes of hyperthyroidism, where there is excessive production of thyroid hormones. Graves  disease is an autoimmune disorder, wherein the body reacts against its own tissues. It is very common in women than men, especially after 20 years of age. Family history also has a strong correlation in developing Graves  disease. The high levels of thyroid hormone increase the rate of metabolism, thereby altering weight, mental energy levels, physical stamina, and also mood.

Thyroid hormone is related to metabolism and more amount of it lead to higher metabolism. This causes the following symptoms.

    Intolerance to heat
    Excessive sweating
    Nervousness and anxiety
    Inability sleep, as the mind is always excited
    Increased appetite (sometimes despite weight loss) due to higher metabolism
    Irregular menstrual cycles
    Palpitations (rapid, loud heartbeat)
    Irregular heartbeats (tachyarrhythmia)
    Fine tremors of the extended arms
    Breast enlargement in men, known as gynecomastia
    Extreme moodiness, causing irritability and anger
    Inability to focus and concentrate
    General fatigue and shortness of breath with any exertion
    Increased frequency of bowel movements

In addition, the eye symptoms are quite diagnostic including:

    Protrusion of the eyes (exophthalmos), giving an impression that they are going to fall out
    Double vision
    Excessive tearing
    Increased irritation in the eyes

Diagnosis: The first symptom would be the presence of an enlarged thyroid gland (front of the neck above the collarbone), and the some of the above symptoms would be present.
In addition, tests to check for thyroid gland functioning including T3 and T4 levels would reveal increased amounts of hormone in the blood stream.
As a confirmatory test, the radioactive iodine uptake test also is done, which will indicate increased uptake by the thyroid gland. This indicates that the gland is functioning at an increased pace and requires additional iodine for the production of thyroid hormones.

Treatment: There are two approaches to it, one to control the symptoms and the other to control the thyroid gland per se.

    Beta blockers are very useful in controlling rapid heart rate and anxiety.
    Prednisone may be used to control eye irritation and swelling
    Antithyroid drugs are used to control the production of thyroid
    Radioactive iodine is given orally to control excessive thyroid production
    In severe cases, thyroid gland may be surgically removed partially or completely

Graves  disease is not life-threatening and once symptoms are controlled, the patient s quality of life improves drastically.

Graves' Disease - Things You Should Know About It

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