Pregnancy brings with it the need to be extra careful about the overall well-being of the mother-to-be. Extreme caution has to be taken in managing health, as antibiotics and a lot of other treatment modalities are best avoided during pregnancy. With diabetes becoming common in the younger ages and women choosing to delay pregnancy, there are multiple women who are diabetic and choose to get pregnant later in life.

With diabetes being a chronic and a lifestyle condition, it definitely has its effects on pregnancy. However, the key is to manage diabetes cautiously in such a way that its effects on pregnancy, both the mother and the developing baby, are minimal. The increased blood sugar levels from the mother pass on to the baby, so keeping a close watch on the blood sugar levels is very important.

The maximum effect of diabetes on the baby is during the first few weeks of pregnancy. It is when the vital organs (brain, heart, lungs and kidneys) are forming, and high blood sugar levels can be harmful. This is slightly tricky as most women realise they could be pregnant only after about 6 weeks. If pregnancy is planned, it is best advisable to keep a check on sugar levels much ahead of the pregnancy.
The baby could be used to high levels of sugar while in the womb, and once delivered, it could have too low sugar levels. This needs to be monitored.
Preeclampsia, which is increased protein in the urine and high blood pressure, can happen during the second trimester. This may require the baby to be delivered prematurely.
Babies born to diabetic mothers are often bigger. The baby s pancreas is used to higher sugar levels and so the extra sugar gets converted to fat, which is the reason for the bigger babies. This may also necessitate C-sections.
Pregnancy can induce the development of diabetic retinopathy, which may prevent vaginal delivery, as the woman may not be able to exert the required pressure.
Abnormal calcium and magnesium levels, which need to be monitored for a while after birth
Most diabetic women reach full term if the sugar levels have been under good control.
Diabetic pregnant women are high at risk. However, with advanced medical care, these risks and complications are managed very well producing healthy babies from normal deliveries with effectively no harm to the mother s health. Once a diabetic woman tests positive, it is advisable to seek medical help to plan diet/meal plan, physical activities, exercise regimen, lifestyle changes, and medication dose adjustments. This is not a one-time activity, but needs to be closely monitored with daily blood sugar levels throughout the pregnancy. 

How Can High Diabetes Affect Your Pregnancy?

Thyroid disorders are conditions that affect the thyroid gland, which is a butterfly-shaped gland in front of the neck. There are specific kinds of thyroid disorders that include:

Hypothyroidism
Hyperthyroidism
Goiter
Thyroid Nodules
Thyroid Cancer
Epidemiology, Incidence, and Prevalence
It has been estimated that about 42 million people in India suffer from thyroid diseases.

Hypothyroidism

Hypothyroidism occurs when the thyroid gland produces an insufficient amount of thyroid hormone. It can develop from problems within the thyroid gland, pituitary gland, or hypothalamus. 

Symptoms of hypothyroidism can include:

Fatigue
Poor concentration or feeling mentally "foggy"
Dry skin
Constipation
Feeling cold
Fluid retention
Muscle and joint aches
Depression
Prolonged or excessive menstrual bleeding in women
Common Causes of Hypothyroidism

Hashimoto's thyroiditis (an autoimmune condition that causes inflammation of the thyroid gland)
Thyroid hormone resistance
Other types involving inflammation of the thyroid, such as acute thyroiditis and postpartum thyroiditis
Hyperthyroidism

Hyperthyroidism refers to the excessive production of thyroid hormone, a less common condition than hypothyroidism. Symptoms of hyperthyroidism are usually related to increased metabolism. In mild cases, there may not be apparent symptoms.

Signs and symptoms of hyperthyroidism can include:

Tremors
Nervousness
Fast heart rate
Fatigue
Intolerance for heat
Increase in bowel movements
Increased sweating 
Concentration problems
Unintentional weight loss
Common causes of hyperthyroidism

Graves' disease
Toxic multinodular goiter
Thyroid nodules that overexpress thyroid hormone (known as "hot" nodules) 
Abnormal secretion of TSH
Thyroiditis (inflammation of the thyroid gland)
Excessive iodine intake
Goiter: A goiter is an enlargement of the thyroid gland, regardless of cause. A goiter may be associated with hypothyroidism, hyperthyroidism, or a normal thyroid function. 

Thyroid Nodules: Nodules are lumps or abnormal masses in the thyroid. Nodules can be caused by benign cysts, benign tumors, or less commonly, by cancers of the thyroid. If nodules are excessively large, they may cause symptoms related to compression of nearby structures. 

Thyroid Cancer: Thyroid cancer is more common among adult women than men or youth. About 2/3rd of cases occur in people under age 55. There are different kinds of thyroid cancers depending upon the specific cell type within the thyroid that has become cancerous. Most cases of thyroid cancer have a good prognosis and high survival rates, especially when diagnosed in its early stages.

Investigations

Blood tests are done to measure levels of thyroid hormones. Blood tests are also done to identify antibodies against thyroid tissue, such as titers of antithyroglobulin, antithyroperoxidase, or TSH receptor-stimulating antibodies.

Treatment

Thyroid disorders can be treated with medications or, in some cases, surgery. The treatment will depend on the particular disease of the thyroid.Medications can be given to replace the missing thyroid hormone in hypothyroidism. Synthetic thyroid hormone is given in pill form by mouth. When hyperthyroidism is present, medications can be used to decrease the production of thyroid hormone or prevent its release from the gland. 

Thyroid Disorder - What All Should You Know 

Top 5 things all diabetics must do

As you are aware, diabetes is an increasingly common problem not only in adults but with children and young people too. Preventing or delaying diabetes is possible with a few lifestyle changes. And for those who have been diagnosed with type-2 diabetes, changes in lifestyle can prove beneficial to keep it under control. This is important and should not be taken lightly as diabetes can lead to other serious health complications. There are few simple things which if done regularly can keep you safe and absolutely fine.

5 ways to combat diabetes.

1) exercise - do minimum 45 to 30 minutes of exercise like brisk walking (for people with heart ailments make sure that you have done stress test/tmt). Keep yourself physically active all the time this will help you in losing weight, controlling blood sugar, blood pressure, cholesterol. It will also improve insulin sensitivity in your body. 
2) high fiber diet - include high fiber foods like fruits, vegetables, leafy vegetables, beans, nuts, seeds, and whole grains, cinnamon, green tea in your diet. This will improve your blood sugar level and also reduce your risk of developing diabetes and helps you to lose weight. Do not get into fad diets and tv commercials as they are often misleading.
3) reduce stress - tension and worry releases certain chemicals (stress hormones) which can increase your blood sugar level. Try relaxation therapy like meditation, yoga, music and soundful sleep.
4) restrict intake of alcohol - alcohol increases body weight, triglyceride (cholesterol) level and blood pressure. They may make you unaware of symptoms of hypoglycemia (low blood sugar which may be dangerous). They are empty calorie with no nutritional value. Permissible limit is 2 drinks (60ml) a day for men and 1 drink (60ml) for women, it is also not advisable to smoke.
5) regular check-ups - make sure that you regularly check your blood sugar levels and modify treatment from your diabetologist doctor (if required.) your body and your friend/ relative / colleague's body are different, so is your need of medicine for diabetes as well. What works best for them may not be right for you. So it is my sincere request is to avoid any self medication as it can be dangerous. Regularly undergo screening for early detection of diabetes complications like eye, nerve, heart, foot, kidney.

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Top 5 Things All Diabetics Must Do

Addison s disease is known as adrenal insufficiency or hypocortisolism. It is a hormonal disorder which occurs when adrenal glands which are located just above the kidneys do not produce enough of the hormone. The hormones produced by adrenal glands include cortisol and aldosterone, which are essential for a healthy life.

The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and darkening of the skin also sometimes. Most cases of Addison's disease are caused by autoimmune disorders.
It is quite a rare condition. Only 1 in 1 lakh suffer from this condition. this condition can affect a person of any age group irrespective of sex. To live a normal life people, with this condition, a patient will be required to take their medication regularly.

Cortisol and Aldosterone - What do they do?
The most important function of the cortisol in the body is to respond to stress. It helps the body in using protein, carbohydrates, and fat. It maintains blood pressure, cardiovascular function; and controls inflammation. While as aldosterone helps kidneys in regulating the amount of salt and water in the body   which helps in regulating blood volume and keeping blood pressure under control.

Cause of Addison's Disease
Mostly Addison s disease occurs due to problems with adrenal glands themselves   which is known as primary adrenal insufficiency. While Autoimmune disease accounts for 70% of Addison s disease. In this condition, the body's immune system mistakenly attacks the adrenal glands. This attack destroys the outer layer of the glands.

Some long-term infections such as tuberculosis, HIV, and some fungal infections harm the adrenal glands. It is also caused by the cancer cells that spread from other parts of the body to the adrenal glands.
Less commonly, adrenal glands can also be affected by secondary adrenal insufficiency. It is caused by a problem with the pituitary gland or a problem with the hypothalamus, both located in the center of the brain.
These glands produce hormones that control the production of hormones in the rest of the body. A pituitary hormone called ACTH which turns on cortisol production in the adrenal gland. If ACTH levels are too low, the adrenal glands do not function.
One more cause of secondary adrenal insufficiency is also caused by the prolonged or abuse of steroid hormones such as prednisone.
Symptoms of Addison's disease
The symptoms of adrenal insufficiency grow gradually and the main characteristics are:

Chronic, worsening fatigue
Muscle weakness
Loss of appetite
Weight loss
About 50 percent of the time, one will notice:

Nausea
Vomiting
Diarrhea

A Quick Guide To Addison's Disease!

10 symptoms that signal hypothyroidism

When your thyroid malfunctions, you may face difficult health issues. Hypothyroidism leads to excessive weight gain and a lot of other medical ailments. It can be identified by a bunch of symptoms which if present, should not be taken lightly.

1) weight gain - if there is sudden and unexpected weight gain, this is the earliest and definite sign of an underactive thyroid gland. This means that there are strong chances of lowered levels of t3 and t4 hormones in the body, leading to slow metabolism in the body. People suffering from hypothyroidism face increased body weight which becomes difficult to lose despite maintaining healthy diet and exercising rigorously.

2) constant fatigue - if you have slept well the night before, yet you are tired and if this is a regular feature, then chances are that your thyroid gland is underactive. Being low in energy, it gets difficult to complete daily chores or exercise.

3) swelling in the neck - another telltale sign would be goiter - an abnormal swelling in the neck. The thyroid gland mainly concentrates iodine from the blood to create both the thyroid hormones. If there is iodine deficiency in the body, this process gets disrupted resulting in hypothyroidism.

4) hair loss - hypothyroidism causes hormonal imbalance which in turn causes hair loss. If there is sudden, unexplainable hair loss, chances of hypothyroidism are high.

5) imbalance in body temperature - if you are suddenly feeling too cold, it is advised to get your thyroid tests done.

6) brittle nails - if your nails have become brittle, get chipped very easily and look weak, this could be an indication of hypothyroidism.

7) mood changes - the weight gained and the excessive fatigue, both trigger massive mood swings which at times, the person has no control over.

8) constipation - the contractions of the digestive tract get weakened due to low levels of thyroid hormones resulting in constipation. Chronic constipation without any apparent reason could be an indicator of hypothyroidism.

9) irregular menses - if your periods are irregular, do not take it lightly. This could be most likely because of hormonal imbalances which are caused by hypothyroidism.

10) slower heart rate - if your heart beats at less than 60 times per minute, it could be because of the interference by thyroid hormones.

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10 Symptoms That Signal Hypothyroidism. Do You Have Any Of These?

The adrenal glands, which sit above the kidneys, are very important to your body as they secrete many important hormones. These hormones are required to regulate many functions within the body. The two most important hormones that these glands produce are  cortisol  and  aldosterone . When your body suffers from the condition of Addison s disease, the glands end up producing very little amounts of these hormones. This will result in many functions in the body being adversely affected.


How do you know your loved one is suffering from Addison s disease?
Addison s disease develops overtime and doesn t happen immediately. However, you would be able to notice some of the following symptoms:
Drop in blood pressure which may result in fainting as well
Development of darker skin due to hyperpigmentation
Development of hypoglycemia or low blood sugar
Unexpected weight loss and a decreased appetite in general 
Craving for salt
Extreme fatigue
Irritability and depression
Vomiting, nausea and diarrhea 
Muscle and joint pains
Abdominal pains
Of these, if you start seeing a combination of frequent hyperpigmentation, muscle and joint pains, nausea, vomiting, abdominal pain, extreme fatigue and unexplained weight loss, you should take your loved one to the doctor immediately as these are telltale signs of Addison s disease.


Diagnosis
There are no ways to self-diagnose this disease as it requires proper medical tests. Some of the medical tests that may be advised for this are:
Blood tests: These are done to measure the levels of sodium, potassium and cortisol in your blood.
ACTH tests: This is a test to determine the exact levels of  cortisol  in your blood and whether it is being produced normally or not.
Hypoglycemia test: This is a test to measure whether adrenal glands are producing enough hormones to regulate insulin. If blood sugar is low, it will indicate problems with the adrenal glands.
Imaging tests: Other tests, such as CT scans may also be prescribed to detect problems within your adrenal glands.


Steps to manage Addison s disease 
Pay regular visits to your doctor: This is very important along with regular tests and checkups as other dependent functions may be damaged and suddenly become life threatening. It may fall on you to take your loved one to a doctor regularly for this reason.
Carry bracelets which have your medical information: If your loved one has a tendency to faint due to the problems caused by Addison s disease, it is important that you ensure they always carry bracelets with medical information with them. This way, strangers will be able to recognize the problem and get help quickly in emergency situations. 
Always keep extra medications: This is a very important point as missing a couple of daily doses and medication can result in sudden deterioration of your loved one's  condition. Have all other forms of administering medications handy as well such as syringes among others.

Addison's disease - How to Support a Loved One Suffering from it?

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