Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

Hives, or  Urticaria  in medical parlance, is a skin condition characterized by the appearance of itchy swellings on the skin surface. Hives may break out on any part of your body and can be of different sizes. It is not a prolonged condition and generally lasts for a few hours. Urticaria or hives usually occur due to the secretion of certain chemical substances such as  histamine  from underneath the skin surface.

Some of the possible causes of hives are mentioned below:

Overexposure to sunlight
As a side effect of medicines such as aspirin, painkillers or antibiotics.
Insect bites
Any food related allergy may also trigger hives
People allergic to certain chemicals or latex can also develop hives
Sensitivity to temperature or water can cause hives
Infections such as Hepatitis or chronic diseases such as thyroid may result in the occurrence of hives.
Alcohol or caffeine intake can cause chronic urticaria
The most common symptoms of Hives include:

Skin becomes swollen
Frequent itching sensation
Skin inflammation is also common
You may feel a burning sensation
Within a short span of time, it may disappear and then again reappear on different parts of the body
Red and white patches appear all over the skin surface known as  wheals 
Hives generally go untreated as the condition subsides within a few hours. But sometimes, hives can be chronic or acute in nature. If so, it would require treatment as it can give rise to further complications. Some of the treatment methods are given below:

Corticosteroids may be prescribed by the doctor to control the formation of hives and give relief from inflammation.
Antihistamines (drugs which hinder the impacts of histamines; mainly used for curing allergies) are advised to patients with chronic urticaria. It controls the effects caused due to the discharge of histamines.
Knowing and avoiding the trigger conditions may prove to be helpful.
Applying menthol creams can give comfort due to its cooling properties.

Hives - Causes, Symptoms & Treatments

Hives, also known as urticaria, is characterized by an outbreak of swollen red bumps on the skin. It may cause symptoms of itching, burning or stinging. The disorder can affect any part of the body including the tongue, throat and face. The size of the bumps can vary, they may join together to form plaques. The bumps or plaques appear and disappear until the disorder runs its course. In case of chronic hives, the bumps can last up to six weeks.

Symptoms
The symptoms of this disorder are formation of bumps on the body, severe itching and pain resulting from the bumps. The symptoms can get aggravated by stress, heat and exercise. You may also experience dizziness, chest pain and a swollen throat.

Causes
Chronic hives can be caused when specific cells in the body release histamine in the blood. The exact cause of this disorder is not known. This reaction of releasing histamine in the blood can be triggered by factors like: 
1. Insects
2. Medications to control pain
3. Scratching
4. Exposure to cold and heat
5. Excessive consumption of alcohol
6. Heavy exercise

Being a female and being young raises your risk of being affected by this disorder.


Ayurvedic Treatment
The first line of treatment for hives is the use of home remedies. The doctor will aim to treat any underlying condition, if any. Ayurvedic remedies for hives are holistic and free from side effects. They are based on natural ingredients that do not cause any adverse effects on the body.

The Ayurvedic treatment for this disorder are

Herbs: Certain herbs like turmeric are very effective to treat this condition. It is known for its anti-inflammatory properties that help relieve its symptoms. A mixture of rock salt and mustard oil can be applied on the affected part to foster speedy recovery.
Diet: You need to follow certain dietary guidelines so that the symptoms do not get aggravated. Avoid taking foods that are sour and salty. Include plenty of buttermilk as it has a cooling effect on the body.

Chronic Hives - How Ayurveda Remedies Helpful in Treating it?

Hives or urticaria is an outbreak of reddish swollen bumps around the skin surface, formed mainly due to the body s response to particular allergens. Generally, the infectious bumps are of varied shapes and sizes and last for about 5-6 weeks. Although not a serious medical condition, hives can cause tremendous discomfort to the concerned person and affect his/her daily activities. Hives can be cured with a prescribed dosage of antihistamines or oral corticosteroids.

Causes of hives

Although the exact reason behind their formation is still unknown, researchers suggest that this disorder occurs as a response to involuntary histamine release by the skin blood vessels (that in turn, causes a leakage of blood plasma). Some other factors that can be responsible are:

Hives can occur due to insect or parasite bites.
Hives can also result as a side effect of painkillers such as codeine and other anti- inflammatory drugs such as ibuprofen or ACE inhibitors.
Excessive exposure to sunlight or high levels of stress (leading to high cortisol levels in the body) can also result in hives.
Intense scratching around the same spot can also result to hive formation.
Excessive alcohol intake can render you even more vulnerable to this disease.
Excessive intake of foods such as eggs, fish, nuts, chocolate and berries might also cause hives. Additionally, excessive consumption of certain food preservatives can also trigger the release of histamine.
Suffering from serious underlying medical conditions such as cancer, hepatitis or thyroid disorders can make you prone to chronic cases of hives (which might last for more than 6 weeks).
Symptoms of hives 
The symptoms of hives include, but are not limited to:

Appearances of several reddish welts around the face or arms which might cause a severe itchy sensation.
Painful and abnormal swelling around the mouth
You might also feel tightness in your chest along with recurring bouts of dizziness.
If not treated promptly after diagnosis, hives might result in life-threatening allergic reactions, such as Anaphylaxis (narrowing down of the bronchial tubes, thus causing significant breathing trouble) and auto-immune disorders such as rheumatoid arthritis.

7 Things that Can Cause Hives

Hives are a common allergic reaction that appears in the form of swollen, red bumps or patches on the skin. These usually appear suddenly and cause itchiness. In some cases, it may also sting or burn. Hives can affect any part of the body including the face, ears, tongue, lips and throat. Hives are usually small in size but may grow as large as the size of a dinner plate. In some cases, hives may also join together to form plaques.

Hives are caused as a result of the production of histamines in the body that make plasma leak out of blood vessels in the skin. These histamines are released as a result of an allergic reaction, exposure to chemicals, insect bites, sunlight or adverse reactions to certain medicines. There are four main types of hives:

Acute Urticaria: These hives usually last for less than 6 weeks. They are triggered by insect bites, allergic reactions to food, latex, medicines or by exposure to infections. The most common food items that trigger this type of hives are chocolates, nuts, fish, tomatoes, eggs, soy, wheat and milk. Aspirin and other medicines like ibuprofen, ACE inhibitors and codeine can also trigger these hives.

Chronic Urticaria: Hives that last for longer than 6 weeks fall into the category of chronic urticaria. IT is harder to find what triggers a case of chronic urticaria than it is for acute urticaria. Along with the triggers mentioned above, hormonal disorders, tumours, chronic infections and immune system disorders can also trigger these hives.

Physical Urticaria: Hives caused as a result of physically stimulating skin are called physical urticaria. This includes sudden exposure to heat or cold, sunlight, vibrations, pressure, exercise etc. These hives usually resolve themselves within an hour and only affect the part of the skin that has been stimulated.

Dermatographism: Hives caused by scratching or firmly stroking the skin fall under this fourth category.

Hives can also be genetic in nature. Some people suffer from hereditary angioedema which is a painful swelling under the skin.

Hives caused by an allergic reaction can recur and hence if you suffer from hives you should try and identify the allergen. This can be done by taking an allergen test in a hospital or by changing aspects of your diet and studying the results. Hives are usually treated with antihistamines but in some cases, steroids may also be needed. However, it is usually nothing to worry about.

What Are Hives? What Causes Hives?

Hives, also known as  urticuria  is a skin disorder that is characterized by formation of white or red welts on the surface of the skin. The sizes of the welts may vary and can last for up to six weeks or more. The disease is not life threatening but the general discomfort associated with it can interfere with your daily activities. The symptoms of hives are treated by taking anti-histamines and anti-itching medications.

Let s take a look at the symptoms:
1. Development of red or white welts, especially on torso, arms and the face
2. The welts may cause severe itching
3. Painful swelling on various parts of the body such as cheeks, lips and the insides of the throat
4. You may experience tightness in the chest and feel dizzy

What might be the causes?
Hives occur when certain cells are triggered into releasing histamine (an organic nitrogenous compound). The various factors that trigger this condition are:
1. Insects bites or parasite bites
2. Continuous scratching at the same spot
3. Various pain medications
4. Prolonged exposure to sunlight
5. High levels of stress
6. Excessive consumption of alcohol

This disease can lead to severe complications which have been listed below:
1. Severe allergic reaction: Anaphylaxis is an allergic reaction that causes the bronchial tubes to narrow down thus, obstructing normal breathing. It is a condition that may, in certain cases, lead to death as well. Hence, you need prompt medical attention if you suffer from this complication.

2. Breathing complications: Swelling on the inner parts of the throat may obstruct normal breathing and cause you to pass out. It can also increase the risk of certain immune disorders such as rheumatoid arthritis and celiac disease (a disorder caused by eating gluten rich foods in excess).

Treatment
The treatment for this disorder includes taking anti-histamine medications that help in blocking histamine (organic compounds which help to regulate physiological functioning) in the body. You may also be administered anti-inflammation medications to reduce inflammation. Wear loose clothing and stop scratching away at the affected regions of the body to make sure you do not aggravate the condition.

Hives Rash or Urticuria - 6 Cause Behind Skin Disorder

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