Factors that determine the success of your IVF procedure

IVF or In Vitro Fertilization is a process wherein an egg is fertilized by a sperm in a laboratory dish to form the embryo (baby's first cell) which after growth in artificial medium in the lab is transferred into the uterus of women, In general, a blood sample is collected to determine whether you're pregnant or not about 10-14 days after the eggs are retrieved.

Coming to the success of the procedure, a number of factors are at play and these are:

The age at which you get pregnant

A factor that plays a role in influencing your chances of experiencing success in your IVF procedure is the age at which you opt for this procedure. The lower your age, the chances that you may get pregnant and deliver a healthy child using your own eggs witness an increase. On the other hand, if you're aged 41 and above, or your egg reserve is very low donor eggs are the most preferred option as they help to increase your prospects of meeting a success.

Lifestyle habits

Certain lifestyle factors can significantly affect your prospects of getting pregnant through this route. Smoking can reduce your prospect of success using this procedure by about 50%. It can cause you to have lesser number of eggs retrieved during the procedure while increasing instances of miscarriages. Likewise, obesity, alcohol use, consumption of excessive caffeine and drugs can adversely affect your chances of getting pregnant using IVF.

Cause of Infertility

If your supply of eggs is normal, success rate using IVF is high. Women who suffer from the problem of endometriosis experience lesser chances of getting pregnant than women who have unexplained fertility.

Reproductive history

IVF success rate chances are higher if you've delivered a baby previously using IVF.

Embryo status

Embryos that are better developed with good grade stand a higher chance of experiencing success than less developed embryos. More importantly, not every embryo is able to survive the development process.



What are the factors that determine the success of your IVF procedure?

With any fertility treatment, a failure is possible due to several reasons. Most couples are having a problem while conceiving a baby and seek various fertility treatments with hope. When things happen otherwise, and the treatment fails, they miserably suffer.

What is IVF?

IVF or In Vitro Fertilization is a fertility treatment where eggs are removed from the woman s ovary and fertilized with retrieved sperms in a laboratory dish. The embryo is then transferred to the woman s uterus. The treatment is said to have a success rate of 40 percent; which means that it can fail in 60 percent cases.

So, why does the treatment fail?

Can it possibly fail ? 

Though the success of IVF depends on certain predominant factors like age and overall health, there are two common reasons behind a failure of IVF, and they are:

An abnormal embryo- The most prevalent reason for a failed IVF is an abnormal or incompetent embryo. In most cases, this is due to an irregular number of chromosomes (aneuploidy) in the embryo. This might be because of an abnormal egg or abnormal sperm or when both gametes are abnormal. 

Implantation failure- An underlying implantation dysfunction may prevent the embryo from attaching to the lining of the uterus. When the thickness of the endometrium is thin (less than 9 mm) at the time of progesterone administration, the implantation may fail. Implantation may fail due to surface lesions in the uterine cavity (due to scarring, polyps, or uterine fibroids) as well.

Other reasons are poor ovarian response and pre-treatment stress.

Make IVF a success with Ayurveda

Ayurveda, the ancient system of healing, appropriately prepares you well-ahead of an IVF treatment. The three key aspects of this treatment are   Detoxification, Nourishment, and Lifestyle changes.

Detoxification

The success of IVF is largely dependent on healthy eggs and sperms and a proper implantation of the embryo. Thus, as the first step, Ayurveda suggests that the couple are to be cleansed with Pancha Karma treatment before conception. Known as Beejshuddhi and Sthanshuddhi, the detoxification procedure purifies ovum, sperms, and uterus.

Along with these, other Pancha Karma procedures like Basti, Uttarbasti, Yoniprakshalana, Vamana, and Virechana are performed to improve the health of reproductive organs. Shirodhara helps in reducing the stress levels of the couple.

Nourishment

Diet is an inherent component of Ayurveda treatment. Hence, a diet that increases fertility is advised to the couple. The couple is advised to stay away from certain foods as well.

The fertility diet includes fresh and organic fruits and vegetables, whole grains, dairy proteins, Moong dal, soaked almonds and walnuts, dried fruits like figs, dates, and raisins, ajwain seeds, cumin seeds, and turmeric.

You should refrain yourself from spicy and salty foods and that containing artificial sweeteners, high-fat food, caffeine, alcohol, and excessive meat. Apart from the diet, certain Ayurvedic herbs are prescribed that strengthens the reproductive organs and improve immunity.

Lifestyle Changes

Infertility has become one of the lifestyle diseases. Ayurveda insists that healthy lifestyle is essential to conceive a baby. According to your body constitution, an Ayurvedic expert can guide you to make lifestyle modifications with Dinacharya and Rutucharya. Also, you must ensure adequate sleep and practice yoga (Surya Namaskar, Sarvangasana, Dhanurasana, Shalabasana, and Pranayama) regularly.

When IVF treatment is failing frequently, you tend to lose hope. However, with Ayurveda, there is definitely hope for success in conception.

How Ayurveda Can Help In Conceiving When Everything Else May Fail?

Frozen Embryo Transfer or FET is an extremely effective method to conceive a pregnancy. Recent studies have proved that there is a increased chance for pregnancy when the embryos, which get used are frozen and get placed inside the uterus at a time right after the ovaries are stimulated. Still, certain issues can arise with the transfer of frozen embryo, such as:

A Thin Lining of the Uterus
Research has shown that there are not many women who get pregnant if the lining in their uterine does not tend to thicken enough. It is not clear exactly why this problem occurs in most women and moreover there is no sure shot treatment to make the lining of the uterine thick. The experts on fertility would try out different methods like increasing the amount of estrogen or change the way how estrogen is given. There are other instances when women might be given supplemental medicines, while for some, the problem will continue to exist.

What Should Be Done In Case The Problem Persists?

In case the problem continues for some women, then there are certain approaches which experts might look to adopt. The first one is to cancel the transfer of embryo and try once again at any later stage, that too with a different treatment method.
The second option which they could think of is to go ahead with the transfer, wherein they might feel that a thin lining does not necessarily mean that it is impossible for a woman to get pregnant but definitely the efficiency would be reduced.
One last option is to make use of the opportunity for undergoing additional tests which would help them to assess the ability of the uterus to allow implantation of the embryos.
Unexpected Ovulation
For enabling the embryos to get implanted into uterus, placing them very precisely and at the appropriate time is important. This is regarded as the window of implantation. The time taken, is based on the time frame since progesterone reaches the lining of the uterine.

Doctor knows the exact time to place the embryos, right from the time he or she instructs a woman to start having progesterone supplements. In case a woman was to ovulate, the production of progesterone would begin earlier than the normal time and would lead to the shift of the window of implantation. As identifying the correct time of ovulation is almost impossible, so that would lead to some sort of uncertainty into the timing.

Due to this reason, there are doctors who would use medication in order to prevent unexpected ovulation from occurring. Generally an injection called Lupron is usually used as medication.

Timing for the Embryo Transfer is Inappropriate
This is a problem related to early ovulation. There are case when the implantation window is shifted, still the timing of the transfer becomes accurate. Recent studies have shown that quite a nominal percentage of women might have a window of implantation, which could be either earlier or later than normal time. A test called the Endometrial Receptivity Array can help determine at what time is the window of implantation open.

Frozen Embryo Transfer - Complications Associated With It!

Intracytoplasmic Sperm Injection i.e. ICSI is different from conventional IVF i.e. In Vitro Fertilization because a single sperm is selected by the embryologist to be injected by a needle into the egg rather than a dish with many sperms placed near the egg so that the fastest swimming sperm enters it. Once the sperm is injected directly into the egg, it fertilizes, after which the embryo is transferred into the womb or uterus. 

Your doctor might recommend ICSI treatment for you if you have an extremely low sperm count resulting in infertility or other medical sperm conditions such as poor motility or poor morphology. It may also be suggested if prior attempts at IVF procedures have failed in fertilizing the egg or the fertilization rate is extremely low. You must also consider ICSI treatment if you resort to embryo testing or if the sperm needs to be collected from the epididymis or testicles surgically. 

However, you must keep in mind that if your partner has a genetic problem resulting in low sperm count, it could be passed on to your child, if you decide to use your husband's sperm for this process.

Success Rates of ICSI:
The success rate of ICSI treatment depends on your age and your fertility problem. Your eggs are healthier when you are young and as you age, chances are that they will become less healthy.
1. 35 per cent if you are under 35 years of age
2. 29 per cent if you are between 35 to 37 years of age
3. 21 per cent if you are between 38 to 39 years of age
4. 14 per cent if you are between 40 to 42 years of age
5. 6 per cent if you are between 43 to 44 years of age
6. 5 per cent if you are above 44 years of age

Advantages of ICSI Treatment:
Intracytoplasmic Sperm Injection gives you a chance to conceive a child genetically when most other options are exhausted. Males may be unable to ejaculate on the day the eggs are collected due to anxiety. ICSI proves to be advantageous because sperm may also be surgically extracted for this process. It is extremely helpful for those couples who suffer from unexplained infertility. However, one of the most important factors is that ICSI treatment does not affect your child's physical or mental health.

Intracytoplasmic Sperm Injection (ICSI)

There are some commonest misconceptions about infertility and these misconceptions should be eliminated as soon as possible so that the actual facts can be known. There are many online sites where you can find detailed information on the scientific explanations regarding infertility and you can follow them.

List of myths and facts regarding infertility

1. Myth: The menstrual cycle of a woman is for 28 days.
Fact: Normal cycle ranges between 21 to 36 days.

2. Myth: A woman can have pregnancy on the day one of menstrual cycle.
Fact: The released eggs remain viable for almost 12-14 hours and a woman can get pregnant after an intercourse done two days after ovulation and five days before ovulation.

3. Myth: Infertility occurs due to stress.
Fact: Ovulation can surely get delayed due to hormone suppression, but infertility does not occur due to stress.

4. Myth: Sperms stay active for few hours.
Fact: Sperms stay alive at least for five days.

5. Myth: Men with a higher sexual drive will have a normal sperm count.
Fact: There is no relation in between fertility and virility. Sometimes, it has been found that men having a higher sex drive do not produce sperms.

6. Myth: Women have to wait for three months to conceive after stopping the usage of contraceptive pills.
Fact: As soon as a woman stops pill usage, hormonal levels go back to normal condition, as a result of which ovulation begins immediately.

7. Myth: Only females have infertility troubles.
Fact: Both women and men suffer from infertility troubles as per the current scientific studies.

8. Myth: Ovulation occurs in a woman on the 14th day of menstrual cycle.
Fact: Ovulation can be calculated by counting 14 days backwards from the past menstrual cycle's last day.

9. Myth: Daily sex can increase conceiving chances.
Fact: During ovulation, having sex each day, especially in between 12 to 16th day of the cycle can be the best timing.

10. Myth: Fertility troubles occur at 35.
Fact: Peak fertility timing in a woman's life is 20 and this might continue until late 30s. Fertility troubles might even arrive at a younger age. With age, conception chances get declined, especially after 35.

Myths & Facts About Infertility

Often most couples face difficulty in trying to conceive and are distraught by the fact that they cannot have a child of their own by natural methods. Nowadays, there are countless alternative options for trying couples to find a solution to this pressing issue.

In vitro Fertilization or IVF is a procedure in which the doctor combines the sperm from the man and egg from the woman to develop an embryo in a laboratory. This step is carried out in a test tube and is therefore referred to as a test tube baby.

Afterwards, the embryo will be transferred back into the woman s womb. The in vitro fertilization procedure was advanced in order to help women suffering from dysfunctional fallopian tubes. In a situation where IVF fails to provide help to the concerned couple, surrogacy is suggested.

Procedure of IVF:

The IVF procedure begins with hormone therapy on the female candidate s body. This is done in order to promote the development of eggs within her ovary. The eggs are then collected and put in a test tube for fertilization. This facilitates the production of a number of embryos. After four days in the incubator, one of the embryos will be transferred within the mother s womb for implantation.

What is Surrogacy and How is it Different?

Surrogacy comes as the next obvious step in light of an IVF procedure failing to make the mother pregnant. In this procedure, the eggs are implanted within the womb of another woman who is referred to as the surrogate. The surrogate keeps the baby within her womb for nine months and gives birth to the child.

Compared to an IVF procedure surrogacy is a very complex process where there are a number of legal, emotional and financial factors involved.

Often couples might take the route to surrogacy as the first option after the woman experiences repeated miscarriages when both the partners have been trying for a number of years and have not met with any success. Other reasons for considering surrogacy include Hysterectomy and frail health condition of the woman that makes her prone to further complications and risks.

Basic Difference:

The basic difference between IVF and surrogacy is that in IVF the egg is fertilized outside the body of the woman whereas in surrogacy, the egg is implanted in another woman s womb and she carries the child for nine months.

The Major Differences Between IVF & Surrogacy!

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