Frozen Embryo Transfer or FET is an extremely effective method to conceive a pregnancy. Recent studies have proved that there is a increased chance for pregnancy when the embryos, which get used are frozen and get placed inside the uterus at a time right after the ovaries are stimulated. Still, certain issues can arise with the transfer of frozen embryo, such as:

A Thin Lining of the Uterus
Research has shown that there are not many women who get pregnant if the lining in their uterine does not tend to thicken enough. It is not clear exactly why this problem occurs in most women and moreover there is no sure shot treatment to make the lining of the uterine thick. The experts on fertility would try out different methods like increasing the amount of estrogen or change the way how estrogen is given. There are other instances when women might be given supplemental medicines, while for some, the problem will continue to exist.

What Should Be Done In Case The Problem Persists?

In case the problem continues for some women, then there are certain approaches which experts might look to adopt. The first one is to cancel the transfer of embryo and try once again at any later stage, that too with a different treatment method.
The second option which they could think of is to go ahead with the transfer, wherein they might feel that a thin lining does not necessarily mean that it is impossible for a woman to get pregnant but definitely the efficiency would be reduced.
One last option is to make use of the opportunity for undergoing additional tests which would help them to assess the ability of the uterus to allow implantation of the embryos.
Unexpected Ovulation
For enabling the embryos to get implanted into uterus, placing them very precisely and at the appropriate time is important. This is regarded as the window of implantation. The time taken, is based on the time frame since progesterone reaches the lining of the uterine.

Doctor knows the exact time to place the embryos, right from the time he or she instructs a woman to start having progesterone supplements. In case a woman was to ovulate, the production of progesterone would begin earlier than the normal time and would lead to the shift of the window of implantation. As identifying the correct time of ovulation is almost impossible, so that would lead to some sort of uncertainty into the timing.

Due to this reason, there are doctors who would use medication in order to prevent unexpected ovulation from occurring. Generally an injection called Lupron is usually used as medication.

Timing for the Embryo Transfer is Inappropriate
This is a problem related to early ovulation. There are case when the implantation window is shifted, still the timing of the transfer becomes accurate. Recent studies have shown that quite a nominal percentage of women might have a window of implantation, which could be either earlier or later than normal time. A test called the Endometrial Receptivity Array can help determine at what time is the window of implantation open.

Frozen Embryo Transfer - Complications Associated With It!

PMS is one of the worst food sensitive diseases. Symptoms include moodiness, bloating and headache. All it takes is one symptom to crop up for the whole body to go down. While environmental changes and preventive measures play a crucial role in dealing with this condition, careful choice of food goes a long way in keeping PMS under control. Here is a list of some best and worst food for PMS:

Foods that are Good During PMS:

Brussels sprouts, Artichokes and Broccoli: These veggies with high fibre content are known to ease bloating. Furthermore, the high water content of these veggies effectively deals with gas, discomfort, and puffiness. The idea is to refrain from foods with high sodium content that only contributes to the suffering.
Quinoa, what berry and popcorn: These foods help to deal with a short temper which is a very common occurring of PMS. Some other good effects of a high carb diet such as these include fighting anxiousness, depression and maintain composure. Consuming whole grain on a daily basis also helps to keep the mood cheerful. This happens because of the added secretion of the feel good factor hormone called serotonin.
Banana: Many women tend to face sleep disturbances before the period sets in. A recent study at the John Hopkins University found that less sleep before the period makes a woman susceptible to cramps and discomfort. Banana contains melatonin. The latter helps the body maintain its natural rhythm.
Eggs: The cravings during PMs can be very difficult to handle. It is therefore very important to start the day a very healthy breakfast. The right amount of protein and healthy fat present in an egg helps to keep the body energised throughout the day. Scrambled egg and an ounce of chicken is a perfect answer to PMs craving.
Some foods to avoid during PMS:

Processed fats: Processed fat contains a lot of processed fats, sodium and salt. Processed fats make a woman puffy and increment bloating. Processed foods contain very high protein content that becomes very difficult for the body to process during PMS.
Sugary foods: Craving for sugary food is pretty normal during PMS. However, too much sugar consumption during PMS fluctuate the blood sugar level. They also aggravate tension and mood swings. The latest study has found that refined sugar can disturb the immune system and creates a lot of fatigue in a woman.
Caffeine: Restricting caffeine during the period can help prevent the cramps and bloating. Certain caffeine such as coffee, cigarettes and chocolate can aggravate breast tenderness, anxiety, and depression. What's more, they systematically create a craving for sweet and other caffeine-related stuff. A better alternative to caffeine during PMs is herbal and green tea, water and fruit juice.

PMS - Foods You Must Have or Avoid During It!

During pregnancy, your body is subjected to several physiological changes including increased hair fall, continuous indigestion, headaches, development of varicose veins, skin pigmentations and so on. The growing baby bump hinders free movement as well. Quality time with your husband or partner is helpful, but is not the best way to relax you. During pregnancy many partners stop having sex due to body issues. Intercourse is extremely important to comfort an expecting mother. Going by a few sex positions cited below, partners can enjoy pregnancy without a speck of stress.

1. Spooning- In spooning a woman lies on one of her sides while the male partner lies behind her on his left or right side. Both partners should lie on the same side or if not they will end up turning their backs at each other. Penetration happens from behind. This position enables shallow penetration, which is good for the baby.

2. Do it like a clip- In this case two bodies should align like a clip. The man lies on his back while the woman is on the top facing him. Her knees are folded next to him and she is in the shape of an arch. Her hands serve as support as they are firmly placed on the bed behind her arching back. There is ample space for the bump.

3. Perch on him- It is healthier to avoid pressure on the abdominal region when pregnant. Make your man sit on a stable surface; say a stool or a chair. Sit on his lap with your back against his chest. This way the woman can regulate the depth of penetration by moving backward and forward. She is on her toes and her abdomen faces no weight.

4. Do it the Amazon way- The Amazon style of intercourse needs to be carried out on a chair or a stool. The male partner remains seated while the woman sits on his lap facing him with her legs across his sides. The baby bump is comfortably positioned between the partners and the lady takes charge by moving up and down.

5. Doggy style- The doggy style keeps the expecting mother away from exertion. She crouches on her hands and legs while the male partner enters her body from behind.

6. Living Room style- Let your rounded belly rest against the softness of the living room couch. Kneel on the couch to suit your feasibility, while your partner penetrates you from behind. The pregnant woman balances her body by holding on to the couch with her hands.


6 Sex Positions During Pregnancy

Sit at the dinner table, and you'd find yourself invariably extending your hand to the glass of water on the side of your plate. While you may think it's absolutely necessary to have a glass of water during your meals, the truth is this habit of yours might be damaging your health. Read on to find out how.

1. It dilutes your gastric juices -
When the digestive acids (acids responsible for the digestion and breakdown of food as well as for killing infectious agents ingested with food) present in your stomach are diluted with water, they bring about a slowdown in the functioning of your entire digestive system. This slowdown results in food remaining lodged in your stomach for a longer period than normal, thereby causing indigestion.

Additionally, the reaction caused by the dilution of water and stomach acids can give rise to cramps in your tummy.

2. It reduces the saliva in your mouth -
The same thing that happens to the acids in your stomach, happens to your saliva as well. Water dilutes the saliva, which stops the breakdown of food in your mouth. Also, your saliva is responsible for stimulating your stomach to release digestive enzymes and prepare itself for the process of digestion. By drinking water with your meals, such signals sent by your saliva to your stomach become much weaker. All these together can make digestion very difficult.

3. It causes acidity -
Studies show that drinking water with your meals not only leads to the dilution of digestive enzymes, but also brings about a reduction in the secretion of digestive enzymes. This causes the undigested food in your stomach to leak into the lower part of your oesophagus (food pipe), causing acidity and heart burn. 

4. It increases insulin production -
Sipping on water in the middle of lunch (or any other meal for that matter) causes a spike in your insulin levels just as glycaemic foods (foods with high starch or sugar content such as honey, potatoes, white bread, rice to name a few) would. When your body is unable to digest food properly, it usually tends to convert the glucose filled part of that food into fat and stores it, reason why your blood sugar levels see an upsurge.

5. It adds to your weight -
Since drinking water causes an increase in insulin levels in your body (as the food you eat is converted to fat), it can result in the piling of extra weight on your body. This is because a weak digestive system is one of the major causes behind obesity.

Try having your meals with less salt and drink water 30 minutes before each meal to control your thirst when you're eating. This can help you in controlling the negative effects that drinking water with your meals can have on your health.

Make a wise choice and stay healthy. Feel free to ask me more questions you might have.

Watch What Happens When You Drink Water Along With Your Food. It'll Leave You Thinking!

If you lose a baby before 24 weeks of pregnancy, it is called a miscarriage. If this happens in the first 3 months of pregnancy, it is known as an early miscarriage. Unfortunately, early miscarriages are common, with 10 20 in 100 (10 20%) pregnancies ending this way. Late miscarriages, after 3 months of pregnancy but before 24 weeks, are less common: 1 2 in 100 (1 2%) pregnancies end in a late miscarriage. When a miscarriage happens three or more times in a row, it is called recurrent miscarriage. Recurrent miscarriage affects 1 in 100 (1%) couples trying to have a baby.

Why does recurrent miscarriage and late miscarriage happen?

Sometimes there is a reason found for recurrent and late miscarriage. In other cases, no underlying problem can be found. Most couples are likely to have a successful pregnancy in the future, particularly if test results are normal.

There are a number of factors that may play a part in causing recurrent and late miscarriage:

Age, the older you are, the greater your risk of having a miscarriage. If the woman is aged over 40, more than 1 in 2 pregnancies end in a miscarriage. Miscarriages may also be more common if the father is older.
Antiphospholipid syndrome (APS- a syndrome that makes your blood more likely to clot) is uncommon but is a cause of recurrent miscarriage and late miscarriage.
Thrombophilia (an inherited condition that means that your blood may be more likely to clot) may cause recurrent miscarriage and in particular late miscarriages.
Genetic factors, about 2 5 in 100 couples (2 5%) with recurrent miscarriage, one partner will have an abnormality on one of their chromosomes (the genetic structures within our cells that contain our DNA and the features we inherit from our parents). Although this may not affect the parent, it can sometimes cause a miscarriage
Weak cervix is known to be a cause of miscarriage from 14 to 23 weeks of pregnancy. This can be difficult to diagnose when you are not pregnant. It may be suspected if in a previous pregnancy your waters broke early, or if the neck of the womb opened without any pain.
Developmental problems of the baby may lead to a miscarriage but are unlikely to be the cause of recurrent miscarriage.
Infection that makes you very unwell can cause a miscarriage. Milder infections that affect the baby can also cause a miscarriage. The role of infections in recurrent miscarriage is unclear.
An abnormally shaped uterus may contributes to recurrent miscarriage or late miscarriages. However, minor variations do not appear to cause miscarriage.
Diabetes and thyroid problems can be factors in miscarriages. They do not cause recurrent miscarriage, as long as they are treated and kept under control.
It has been suggested that some women miscarry because their immune system does not respond to the baby in the usual way. This is known as an alloimmune reaction. There is no clear evidence to support this theory at present. Further research is needed.
Are there any other risk factors?

Being overweight increases the risk of miscarriage. Smoking and too much caffeine may also increase the risk. Excessive alcohol is known to be harmful to a developing baby and drinking five or more units a week may increase the risk of miscarriage.

The chance of a further miscarriage increases slightly with each miscarriage. Women with three miscarriages in a row have a 4 in 10 chance of having another one. This means that 6 out of 10 women (60%) in this situation will go on to have a baby next time. 

Why are investigations helpful?

Finding out whether there is a cause for your recurrent miscarriage or late miscarriage is important as your doctor will be able to give you an idea about your likelihood of having a successful pregnancy. In a small number of cases there may be treatment available to help you.

What investigations might be offered?

Blood tests:

For APS- APS is diagnosed if you test positive on two occasions 12 weeks apart, before you become pregnant again.
For thrombophilia- If you have had a late miscarriage you should be offered blood tests for certain inherited thrombophilias.
To check you and your partner s chromosomes for abnormalities. You may be offered this test if your baby has been shown to have abnormal chromosome
Tests for abnormalities in the baby You should be offered tests to check for abnormalities in your baby s chromosomes. This is not always possible but may help to determine your chance of miscarrying again. If you have had a late miscarriage you may also be offered a postmortem examination of your baby. This will not happen without your consent and you will have the opportunity to discuss this with your health team beforehand.

Tests for abnormalities in the shape of your uterus. You should be offered a pelvic ultrasound scan to check for any abnormalities in the shape of your uterus. If an abnormality is suspected, further investigations may include a hysteroscopy (a procedure to examine the uterus through a small telescope which is passed through the vagina and cervix) or a laparoscopy (a procedure in which a surgeon uses a fine telescope to look inside the abdomen and pelvis).

Tests for infection. If you have had a late miscarriage, tests such as blood samples and vaginal swabs may be taken at the time to look for any source of infection.




What are my treatment options?

Treatment for APS

If you have APS and have had recurrent miscarriage or a late miscarriage, treatment with low-dose aspirin tablets and heparin injections in pregnancy increases your chance of having a baby. Aspirin and heparin make your blood less likely to clot and are safe to take in pregnancy.

Having APS means you are at increased risk of complications during pregnancy such as pre-eclampsia, problems with your baby s growth and premature birth. You should be carefully monitored so that you can be offered treatment for any problems that arise.

Treatment for thrombophilia

If you have an inherited tendency to blood clotting (thrombophilia) and have had a miscarriage between 12 and 24 weeks of pregnancy, you should be offered treatment with heparin. At present there is not enough evidence to say whether heparin will reduce your chance of miscarriage if you have had early miscarriages (up to 12 weeks of pregnancy). However, you may be still offered the treatment to reduce the risk of a blood clot during pregnancy.

Your doctor will discuss what would be recommended in your particular case.

Referral for genetic counselling

If either you or your partner has a chromosome abnormality, you should be offered the chance to see a specialist called a clinical geneticist. They will discuss with you what your chances are for future pregnancies and will explain what your choices are. This is known as genetic counselling.

Monitoring and treatment for a weak cervix

If you have had a miscarriage between 14 and 24 weeks and have a diagnosis of a weak cervix, you may be offered an operation to put a stitch in your cervix. This is usually done through the vagina at 13 or 14 weeks of pregnancy under a general or spinal anaesthetic. Your doctor should discuss the surgery with you.

If it is unclear whether your late miscarriage was caused by a weak cervix, you may be offered vaginal ultrasound scans during your pregnancy to measure the length of your cervix. This may give information on how likely you are to miscarry. If your cervix is shorter than it should be before 24 weeks of pregnancy, you may be offered an operation to put a stitch in your cervix.

Surgery to the uterus

If an abnormality is found in your uterus, you may be offered an operation to correct this.

Hormone treatment

Taking progesterone or human chorionic gonadotrophin hormones early in pregnancy has been tried to prevent recurrent miscarriage. More evidence is needed to show whether this works.

Immunotherapy

Treatment to prevent or change the response of the immune system (known as immunotherapy) is not recommended for women with recurrent miscarriage. It has not been proven to work, does not improve the chances of a live birth and may carry serious risks (including transfusion reaction, allergic shock and hepatitis).

What if no cause is found?

Where there does not appear to be a cause for recurrent miscarriage or late miscarriage, there is currently no evidence that heparin and aspirin treatment reduces the chance of a further miscarriage. For that reason this treatment is not recommended in these circumstances.

What does this mean for us in the future?

You and your partner should be seen together by a specialist health professional. Your doctor will talk to you both about your particular situation and your likelihood of having a further miscarriage and a successful pregnancy. If a cause has been found, possible treatment options will be offered to you to improve your chance of a successful pregnancy.

For couples where no cause for recurrent miscarriage has been found, 75 in 100 (75%) will have a successful pregnancy with this care. It is worth remembering that the majority of couples will have a successful pregnancy the next time even after three miscarriages in a row.

Recurrent And Late Miscarriage - Tests & Treatment For Couples!

What are the factors that make a woman fertile? + The most effective way to address infertility

Infertility is the inability to get pregnant after a year of unprotected intercourse. Both men and women can be infertile.

In about one-third of cases, the cause of infertility involves only the male.

In about one-third of cases, the cause of infertility involves only the female.

In the remaining cases, the cause of infertility involves both the male and female or no cause can be identified.

Women are born with a finite number of eggs. Thus, as the reproductive years progress, the number and quality of the eggs diminish. The chances of having a baby decrease by 3% to 5% per year after the age of 30 and this reduction is noted to a much greater extent after age 40.

Female infertility can also be caused by a number of factors including:

1. Damage to fallopian tubes

Damage to the fallopian tubes can prevent contact between the egg and sperm. Pelvic infections, endometriosis, and pelvic surgeries can lead to fallopian tube damage.

2. Hormonal causes

This can lead to ovulation disorders which prevent the ovaries from releasing eggs such as in polycystic ovary syndrome ,  hyperprolactinemia or disorders of the thyroid gland - hyperthyroidism / hypothyroidism, can interrupt the menstrual cycle and cause infertility.

3. Cervical causes

A small group of women may have a problem in which the sperm cannot pass through the cervical canal. Whatever the reason is , this problem may be treated with intrauterine inseminations.

4. Uterine causes

Abnormal anatomy and distortion of the uterine cavity due to the presence of polyps and fibroids or problem with the endometrial lining can lead to failed implantation of the embryo.

Endometriosis occurs when endometrial tissue grows outside the uterus - often affecting the function of the ovaries, uterus, and fallopian tubes.

5. Primary Ovarian Insufficiency:

Also called as Premature Menopause, when the ovaries stop working prematurely before the age of 40. Certain conditions are associated with early menopause like immune system diseases, radiation or chemotherapy and smoking.

Causes of male infertility may include:

1. Abnormal sperm production or function due to various problems, such as undescended testicles, genetic defects, health problems including diabetes, prior infections such as mumps, trauma or prior surgeries on the testicles or inguinal region.

2. Problems with the delivery of sperm, due to sexual problems, such as premature or retrograde ejaculation, certain genetic diseases, such as cystic fibrosis, structural problems, such as blockage of the epididymis, or damage to the reproductive organs.

3. Overexposure to certain chemicals and toxins, such as pesticides, radiation, tobacco smoke, alcohol, frequent exposure to heat can elevate the testicular temperature, impairing sperm production.

4. Damage related to cancer and its treatment, including radiation or chemotherapy for which timely cryopreservation can be done for future use.

5. Unexplained infertility, In approximately 20% of couples the cause cannot be determined using the currently available methods of investigation.

Why is IVF the best way to treat infertility in women?

Conception is a complicated process that depends on upon many factors:

On the production of healthy sperm by the man and healthy eggs by the woman

The sperm's ability to fertilize the egg when they meet.

The ability of the fertilized egg (embryo) to become implanted in the woman's uterus

IVF (or in-vitro fertilization) is a lab procedure where the sperm and the egg are combined in a dish (where fertilization takes place) and is followed by transferring the embryo (the fertilized egg) into the uterus. It is increasingly being used as a method to conceive as it has been established as a safe procedure that helps bypass a number of complications women may face while conceiving such as ovulation problems and issues with the fallopian tube.

Even women who face issues such as PCOS, endometriosis, and premature ovarian failure can conceive through this process. Moreover, IVF has been in practice since 1978 and has a safe track record. The success rates of IVF are high as well, making it a preferred procedure for couples who suffer from fertility problems. Unexplained infertility can also be treated with the help of this procedure.



What factors that  make a woman fertile? + The most effective way to address infertility

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