Gastric (stomach) cancer occurs when malignant cells form in the lining of the stomach. By far, it is known to be the second most common cause of cancer-related deaths not only in Asia but also worldwide. Though it can affect both male and female populace, it is seen more commonly in men and in people aged 50 years or older.

Type: Gastric cancers can present as one of the following types - 

Adenocarcinoma: Begins in the glandular cells lining the inside of the stomach. This forms a majority of the stomach cancers.
Lymphoma: Begins in immune system cells present in the walls of the stomach. Occurrence of lymphoma, in the stomach, is rare.
Carcinoid Tumor: Begins in hormone producing cells of the stomach.  Occurrence of carcinoid cancer, in the stomach, is rare.
Gastrointestinal Stromal Tumor (GIST): begins in nervous system cells of the stomach. Occurrence of GIST, in the stomach, is rare.
Gender: It affects both male and female populace.

Etiology: The factors that are associated with increased risk of gastric cancer include the following mostly  

 Helicobacter Pylori  bacterial infection in the stomach is a common cause of gastric cancer of both the intestinal (expanding) & diffuse (infiltrative) type. Furthermore, studies indicate that high salt intake is synergistic with H. Pylori infection in the manner that it is likely to increase the risk of gastric cancer that is induced by H. Pylori bacteria.
Smoking, consuming alcohol, red meat, salty/ smoked/ processed foods, low intake of fruits and vegetables, diets rich in nitroso compounds, eating foods contaminated with aflatoxin fungus etc all.
Atrophic gastritis characterized by chronic stomach inflammation is known to increase the risk multi-fold. Chronic gastric inflammation can lead to atrophy of the gastric mucosa, metaplasia, dysplasia and finally carcinoma.
History of pernicious anaemia, gastric ulcers, adenomatous gastric polyp etc all.
Family history of gastric cancer. Several familial syndromes that have been associated with a pre-disposition to gastric cancer include familial adenomatous polyposis, Lynch syndrome, Peutz-Jeghers syndrome and e-cadherin mutation (diffuse type)
Blood group A, Obesity etc all are known to be associated with diffuse or cardia gastric cancer.
Low socioeconomic status - persistent lifestyle issues/ irregularities including high stress coupled with an improper diet/ dietary pattern.
Epidemiological evidence is indicative of a risk or pre-disposition to gastric/ stomach cancer for people suffering from diabetes mellitus (DM).
Very high dose ionizing radiation exposure is an uncommon risk for gastric cancer.
Features: There are often no early stage symptoms. Early stage symptoms, if any, are non-specific and are likely to be ignored, thus delaying the diagnosis most often. Hence, gastric/ stomach cancer is often detected at an advanced stage where the disease is either locally advanced or metastatic. The various presentations (of signs & symptoms), by stage (early or advanced), of gastric cancer are as enumerated below:

Early Stage   can present with one or more of the following non-specific symptoms/ signs -

Dyspepsia (Indigestion),
Stomach/ Epigastric discomfort,
Bloated feeling after eating,
Mild Nausea/ Vomiting,
Blood in Vomit (Haematemesis),
Heartburn,
Weight loss (Cachexia)
Anaemia,
Occult blood in stool/ Melaena,
Advanced Stage   presents with one or more of the following symptoms/ signs -
GI Bleeding with black tarry stools (Melaena),
Persistent Nausea/ Vomiting,
Blood in Vomit (Haematemesis),
Early Satiety,
Anaemia,
Loss of Appetite (Anorexia),
Weight loss (Cachexia),
Persistent pain in the abdomen,
Fluid build-up in the peritoneal cavity (Ascites),
Edema of the lower extremities,
Liver Enlargement (Hepatomegaly)/ Jaundice,
Difficulty swallowing food (Dysphagia)
Screening: Is generally recommended for asymptomatic populations in high incidence areas or as surveillance for high risk individuals. The goal of screening, as usual, is to be able to detect & diagnose gastric cancer at an early stage which is potentially curable. It is mostly endoscopic/ radiologic.
Diagnosis: Following are the diagnostics employed in gastic cancer - 

Physical Examination: May be remarkable for palpable abdominal mass, weight loss (cachexia), abdominal distension, ascites, hepatomegaly, lower extremities edema and lymphadenopathy for gastric cancers in the advanced stage. For early gastric cancers, however, physical examination is largely uninformative.
Blood: Hb- may be low, ESR   raised, tumor markers CEA & CA-19-9 could be raised sometimes in adenocarcinoma but are not frequently elevated. Abnormal blood test results may be indicative of malignancy, but a follow-up gastroscopy/ biopsy is always the gold standard for accurate diagnosis.
Stool: Occult blood may be +ve
Barium Meal X-Ray: Could show a filling defect at the site of the carcinoma/ cancer growth.
Gastroscopy/ Biopsy: Clinches the diagnosis.
Endoscopic Ultrasound: Maximizes tumor staging as it helps determine the depth of invasion of the tumor.
CT Scan: Of chest, abdomen & pelvis helps detect metastatic disease, if any, and also helps stage the disease (TNM) appropriately.
Bone Scan: Helps detect osseous metastasis (bone mets), if any.
Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Surgery (i.e. gastrectomy either sub-total or total), with an adjuvant chemotherapy and/ or radiotherapy as contextually relevant, is the only treatment that is known to cure the disease in light of the prognostic indicators as briefly enumerated in the section below. Chemptherapy and/ or radiation alone cannot be curative. Mostly, it can improve symptoms, and may prolong survival. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as feasible contextually.
Prognosis: For gastric cancer is variable. Preventive measures, earlier diagnosis and right early treatment is key for an effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for an early stage gastric cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. Distal tumors are known to be cured more often than the proximal ones. Again, intestinal-type gastric cancers are known to have a better treatment outlook in comparison to the diffuse-type gastric cancers.

Prevention: Rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an adherence to a relative Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising, de-stressing and relaxation is highly recommended for reducing the risks of many cancers including gastric cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. The consumption of alcohol, if any, has to be strictly in moderation, and is best avoided in a high risk scenario. Smoking is to be avoided too. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly. Not only it is important to eat healthy, but also it is equally important to eat properly. Insufficient chewing, eating until full, eating meals within a short time etc all are best avoided so as to ease off digestive burden on the stomach/ other organs in the GI tract. Last but not the least, consumption of clean and filtered water, natural probiotics like freshly prepared yogurt/ butter milk, maintenance of cleanliness & hygiene including oral hygiene etc. all can help guard against H. Pylori infections. Breastfeeding is known to be protective against H. Pylori infections too.

Gastric Cancer - In a Nutshell!

In recent years there has been a rise in gastrointestinal disease due to lifestyle changes. Conditions like irritable bowel syndrome, gastroesophageal reflux disease, nonalcoholic fatty liver, cancer of colon, liver and pancreas have been affecting the young and the elderly equally.

The advancement of medical science has given rise to a series of laparoscopic surgeries relating to gastrointestinal diseases. These surgeries are minimally invasive compared to open surgeries. Let s have a look at the various forms of gastrointestinal surgeries.

Conditions Cured through Gastrointestinal Surgeries:

Gastrointestinal surgery can be used to prevent and treat the following health disorders.

  Peptic ulcer disease
  Barrett s Esophagus
  Hiatal hernia
  Radiation bowel injury
  Gastrointestinal tumours
  Inflammatory bowel disease
  GERD
  Achalasia
  Malignant disease of the pancreas
  Malignant disease of the biliary tract
  Infectious disease of the colon and rectum

Types of Gastrointestinal Surgeries:

Some examples of gastrointestinal surgeries include  

  Colon Cancer Surgery   It may involve local excision which is done in the early stage of colon cancer. Here the doctor inserts a cutting tool into the colon to remove the cancerous growth. Colectomy is the next stage that is performed only when the cancer has spread to the nearby tissues.

  Oesophagal Cancer Surgery   It includes esophagectomy or removing the oesophagus partially leaving the patient with the ability to swallow.

  Gall Bladder Cancer Surgery - It involves four stages of treatment namely Cholecystectomy, Surgical Biliary Bypass, Endoscopic Stent Placement and Percutaneous Transhepatic Biliary Drainage. Each procedure is performed at different stages depending on the severity of the condition.

  Liver Disease Surgery   Liver disease surgery involves Partial Hepatectomy, Liver Transplant and Ablation used at different stages of cancer.

  Pancreatic Cancer Surgery   The four stages of pancreatic cancer surgery includes Whipple procedure, Total Pancreatectomy, Distal Pancreatectomy and Gastric Bypass.

Apart from these open surgeries, the laparoscopic procedures include  

  Laparoscopic Adrenalectomy
  Laparoscopic Appendectomy
  Laparoscopic Nephrectomy
  Laparoscopic Splenectomy

Benefits of a Gastrointestinal Surgery:

  Minimally invasive due to which scarring is less
  Shorter recovery period
  Reduced chances of infection
  Reduced chances of reoccurrence of the disease

Most of these benefits apply specifically to the gastrointestinal surgeries performed using the laparoscopic technique.

With the rampant increase in gastrointestinal diseases among the masses the wide ranges of gastrointestinal surgeries have made treatment and prevention easier and more accessible.

Gastrointestinal Surgery - Everything About It!

Curd is a staple in every household in India; whether it is served with piping hot parathas or by itself after a meal. The simple food item is packed with a number of nutrients and helps in increasing the health benefits in your body.

Here are a few reasons why you should be eating curd, almost every day:

Probiotics help in digestion: Curd, being rich in probiotics (good bacteria), improves digestion as it kills all the harmful bacteria in the digestive tract and aids the proliferation of good bacteria. Probiotics also help in the prevention of various digestive issues such as cramps, bloating and abdominal pain caused due to Irritable Bowel Syndrome.
Promotes weight loss around the belly: A hormone called cortisol, also called the  stress hormone  persuades the fat cells to produce more fat around your belly area. Consuming a cup of curd daily increases the amount of calcium in your body which limits the release of cortisol, thus, helping you lose weight. Curd also retains one-third of lean muscle mass which helps you maintain your physique post those dropped kilos for a longer time.
Curd strengthens your immunity system: A cup of curd is loaded with good bacteria which is essential for fighting off germs, thereby making your immune system stronger and more persistent. Making curd a part of your daily diet is a great idea as it is effective in preventing yeast infections around the vaginal area.
Toughens up your skeletal system: Like all dairy products, curd is rich in calcium which is necessary for strong bones and teeth. Apart from calcium, curd is rich in phosphorous and together, they quicken the bone growth process and helps in preventing arthritis and osteoporosis.
Helps in improving cardiovascular health: Eating curd helps in improving cardiovascular health as it discourages the spread of cholesterol around the arterial area, thus, reducing the risks of a coronary disease. Curd reduces hypertension which is a pre-cursor to most heart ailments.

5 Reasons You Should be Eating Curd Daily 

An essential prerequisite for good health is having regular bowel movements. People all over the world have a misconception about the regularity of bowel movements. Having bowel movements three times a day or three times a week (if that is the routine) is considered regular. Irregularity in bowel movements can often lead to constipation and it is something that should never be ignored. It not only affects our health but also affect our overall being in ways that are unexpected. Let us take a look at some of these unexpected side effects of not pooping regularly:

Constipation can trigger headaches: The cause for a headache can be many things, but the first likely reason is stress. When you do not poop properly, the pain, inconvenience and worry will build up, leading to mental stress. This anxiety can trigger headaches. Also, headache can occur because of dehydration, which is often a result of constipation. By drinking more water, you can get a relief from both constipation and headaches. Moreover, the buildup of toxins in the body also causes a headache. regular is a key channel that releases all the toxins from the body and when that does not work, it is bound to cause problems.
It can cause breakouts: What happens in and out the gut shows up on the skin. Skin conditions like acne, pimple, dark circles and even rashes can occur due to internal gut and digestive issues. When the toxins are not eliminated regularly from the body, they tend to accumulate over time leading to major skin breakouts.
It carries a risk of anal fissures: Due to hardened stool, there is not enough lubrication and this can lead to a tear of the skin. This is called an anal fissure and the prime symptom of this condition is the presence of blood in your stool. So, if you feel pain or see blood while pooping, you need to contact your healthcare provider and relieve your condition.
It may cause Diverticula or Heamerhoids: Long term constipation can lead to certain ailments which tend to form because of the pressure of straining to pass your poop. You can be affected with diverticula which result in bulges or pouches on the lining of the colon area. Or it can also cause a strain in the veins along the rectum and lead to
Hemorrhoids.
It affects your Bladder control: The colon and the bladder share a close relationship with each other. If there is too much pressure on the bladder because of a full colon, it can lead to decreased control of the bladder. Your bladder will not fill all the way, empty badly or cause unexpected leakages. So, chronic constipation can cause apparent leakage problems too.
It can make you lose appetite: Eating food can be a major turn off for people with constipation. Appetite loss is not just an enjoyable form of hunger suppression, but a big inconvenience.

Not Pooping Regularly - Ways It Will Affect Your Body!

Almost all of us have experienced bloating, gas or an upset stomach. Yet some people experience this problem at a chronic level. Gas occurs in the stomach and intestines due to breakdown of food into energy. All of us pass gas, however some people do more than others. An average person passes gas 5-20 times a day.

An upset stomach can often cause problems and can be a difficult battle for many people. Although the symptoms of gas problems often relate to an improper diet, yet other factors may be also responsible.

Causes and Symptoms of Gas Problems

Swallowing air: The swallowed air which is not burped out, passes through the digestive system and is released through the opening of the anus. Hiccups can also occur if you have swallowed excessive air.
Diet: The reaction of different foods varies from one person to another. Also foods that lead to odorous gas may also vary from person to person. Yet, spicy foods and dairy products are the most common causes of gas. Example - Beans, cabbage, onions, radishes, eggs, carbonated drinks, sugar, packaged foods etc.
Medications: Certain medicines and supplements, including prescription drugs, can lead to gas problems and bloating. Further, medications which change the hormonal balance in the body can also cause bloating.
Medical problems: Certain medical conditions such as Irritable bowel syndrome or bowel obstruction can also lead to an upset stomach.
Common symptoms of gas problems include gas pain, cramping, bloating, diarrhoea and constipation. In the worst of cases, gas and bloating indicate colon cancer. Such people experience rapid weight loss, anaemia and blood in stools.

Treatment
Modifying your lifestyle, in particular your dietary practices, is essential to a healthy recovery.

Avoiding foods such as spaghetti, oats, bran, barley, banana, bread etc. which contain high fibre content is important.
You can opt for over the counter medications after consulting your physician. Homeopathy and Ayurveda can be also opted as alternative forms of treatment.

Chronic Gas Problem - Facts You Should Know About it

An infant is usually called a bundle of joy and with good reason. There are simple and carefree, and bring a smile to your face with their antics. However, the mood and health of an infant can be tarnished due to an issue which is known as galactosemia.

What is Galactosemia?
When a baby has galactosemia, he or she will have a problem when it comes to digesting galactose, which is something that is present not only in milk but in all milk products. Galactose is a sort of sugar, just like fructose and glucose is. As a matter of fact, lactose, which is what milk has, is, in fact, a combination of glucose and galactose. Also, when lactose is processed, it is broken down by the human body into its constituents.

The condition is something that is passed down through the genes of the parents of the baby. The condition would occur if the gene which causes a tendency for a baby to have galactosemia is present not only in one parent but both of them. A baby who has the condition will be lacking an enzyme which is known as the GALT enzyme. The enzyme could also not be functioning as it should be under normal circumstances.

When it comes to the problem, it is very important, to say the least, to detect it sooner rather than later as if there is a build-up of unprocessed galactose which is allowed to occur, it can affect the baby adversely and in some cases, it can also be threatening to the life of the baby!

How does it affect a baby?
The problems which can erupt due to galactosemia include issues which affect organs such as the brain, eyes, liver and kidneys. It is interesting to take note of the fact that these are all organs which either have something to do either processing the blood or are heavily dependent on it. While a baby is not in the position in which he or she can communicate the issues that are being faced, when keeping an eye out for galactosemia, the signs which are displayed include an irritability of the baby as well as lacking consumption of the milk of the mother.

Even though galactosemia may not be the case, a doctor should be consulted as the exacerbated issue can include seizures and jaundice. It is to be kept in mind that galactose is something that can be found not only in the milk of the cow but also human milk as well as the milk of other animals such as goats.

Galactosemia In Infants - Know the Reasons Behind It!

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