SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

Cut down flu risk through regular exercise

Cold and flu are common problems which spans across all seasons and affects all age groups, kids and elders alike. However a flu or a viral infection leaves you very weak and vulnerable. A good routine of exercise is the easiest way to keep such infections at bay.

Regular exercise plays an important role in building your immunity against a flu infection. If you exercise for a minimum of 2.5 hours every week, your chances of contracting a flu infection are drastically reduced by almost 10 percent. However it is important that you exercise moderately and on a regular basis to protect your body against the flu.

An effective exercise schedule would involve 150 minutes of moderate exercise such as brisk walking, gardening etc every week. This can also be substituted by 75 minutes/week of vigorous exercise which includes running, playing a sport, aerobics etc. And 2 days for muscle strengthening exercises. Incorporate any one of these regimes in your daily schedule and follow them without fail, as they are the most fool-proof method to prepare your body for the fight against the flu virus.

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Can You Cut Down FLU Risk With Mere Exercising?

How to prevent dengue fever

A painful, mosquito-borne disease, dengue (pronounced dengue) fever is on the rise. While in some cases, it has proved to be fatal, in most cases dengue is curable. There is no vaccination available to protect against this fever. So the best way to avoid is to take precautions.
Here are a few precautions you can take against dengue.

1. Avoid public spaces - avoid densely populated residential areas, as more the people, more the virus can spread.
2. Use insect protection - use mosquito repellents and nets when indoors. Use repellents when going outdoors; this is especially important for children playing outdoors.
3. Use air cooling - use the fan or the air-conditioning when indoors as the air-cooling drives the mosquitoes away.
4. Prevent entry - close all doors and windows tightly before sunset. Ensure there are no gaps for mosquitoes to come indoors.
5. Check for symptoms - if you have any of the symptoms, consult your doctor. It is advisable to keep yourself aware about the symptoms so one can react quickly if needed. Some of the symptoms are:

Severe headaches.
Nausea.
Vomiting.
Sudden rise in body temperature.
Mild bleeding in the gums or nose.
Severe muscle and joint pain.
Acute pain behind the eyes.

The one confusing part of dengue fever is that it can be mistaken for normal fever upon onset. However, it can develop to serious problem. People with a weak immune system and people who have had dengue before, are at the higher risks of contracting this again, and at a bigger scale.



Prevent The Dangerous DENGUE Fever - Follow These Simple Steps

Tuberculosis is an opportunistic infection caused by the bacteria Mycobacterium tuberculosis. The infections occurring in people with weak immunity as compared to the people with a healthy immune system are called as opportunistic infections. As, HIV enters the human body, it replicates and weakens the immune system which in turn increases the risk of contracting Tuberculosis in people already suffering from HIV infection.

An HIV and Tuberculosis co-infection occurs when an individual has both, the HIV infection and an either latent or active TB disease simultaneously.  Each disease acts in speeding up the progress of the other, when HIV and TB infection is present together in the body. HIV infection speeds up the progression from latent to active Tuberculosis, Mycobacterium tuberculosis also accelerates the progression of replication and spread of the HIV infection.

HIV infection and Tuberculosis are totally different type of infectious diseases. HIV is a viral infection and TB is a bacterial one. An HIV infected person will not contract TB unless a contact happens with a TB infected person. TB spreads via droplet infection and is communicable. If a person lives in a country with a high prevalence rate of TB, an HIV patient is highly susceptible to contracting the infection. In the similar manner, a person suffering from TB gets infected with the HIV infection only through the blood and bodily fluids borne route, with unprotected sexual intercourse with an HIV infected individual being the most important cause.

Amongst all the other opportunistic infections, TB occurs at an earlier stage in the course of an HIV infection than most other opportunistic infections. Mortality rate in the co-infected patients is more than twice that of HIV infected individuals without a TB infection. Even if a patient is undergoing anti-retroviral therapy, the death rates remain high in co-infected individuals.The natural history and course of TB gets altered in people with an infected immune system. The damage to immunity due to HIV infection causes a drastic reduction in the pathogen killing capacity of the body. In such patients if there is no anti-retroviral treatment prescribed, then the latency period between the infection and progression of disease gets eliminated. 

An active phase of TB is observed in such individuals progressing within a short span of time, ranging from weeks to months, rather than years as it normally should be spanning. Risk of progression from a latent stage to an active stage of TB is around 10-15 times greater in an HIV infected individual as compared to the non-infected person. Such individuals also communicate the disease more rapidly to others.Pulmonary tuberculosis in an HIV infected person can present similar symptoms like that of a classic TB disease. However, a co-infection can sometimes show less presenting TB symptoms, where even the chest X-ray scans can be observed to be normal. A  subclinical  phase of Tb in co-infected patients can cause delay in the diagnosis of the symptoms and subsequently affect the prognosis due to lack of timely treatment.

Social stigma and discrimination has caused an obstacle in provision of adequate treatment for people with HIV. Proper counseling  and initiatives taken to provide indiscriminate care can aid in identification of co-infection and earlier stages. Anti-retroviral treatment teamed up with anti-tubercular drug regimen is prescribed and a successful treatment for drug sensitive cases of TB can be provided with medications for 6-8 months.

How HIV & TB  Are Related?

Pneumonia is a lung infection that can be potentially fatal if it is not treated on time. This disease may cause fever, cough, cold and congestion and is known to clear within two to three weeks with bed rest and proper remedies at home. Yet, it is best to have it checked by a doctor, especially if it happens to affect a child. The causes of symptoms of this condition are as follows:

Symptoms: The most common symptom of pneumonia is a painful cough with which you will end up throwing out lots of mucus. This mucus or sputum usually comes from the lungs. The patient may also have fever and may experience shortness of breath and shallow breathing on several occasions. Further, chills that cause chattering teeth and shivering, can also afflict the patient, especially during the night. Chest pain is also a common symptom of this condition due to the excessive and persistent coughing, laboured breathing and congestion. Due to this, the patient may also experience accelerated heartbeat and a pounding heart. Nausea, weakness, fatigue and loose motions are some of the other symptoms of this condition.

Causes

Germs: Germs finding their way into the lungs is a sure shot way of contracting pneumonia. These bacteria are most likely to strike when you have just recovered from a flu, cold or fever following which your immunity is pretty low.
Chronic Ailments: Patients who are suffering from chronic ailments like asthma, heart disease, diabetes and even cancer, are at risk of getting pneumonia, in which case immediate treatment will be required so that it does not become a fatality.
Bacteria: While the specific bacteria cannot be diagnosed with the help of tests, the most common bacteria that cause this condition are known as Streptococcus Pneumoniae. Other bacteria that can cause this disease include the Mycoplasma Pneumoniae which can cause a more mild form of pneumonia known as walking pneumonia.
Virus: The viruses that cause influenza like virus A and B can also cause this disease along with the respiratory syncytial virus or RSV. These affect the nose, lungs and throat.
Immunity: When your immune system is impaired or when you have just recovered from a bout of moderate to serious ailments, this virus or bacteria is most rampant and can afflict you. In case the patient is suffering from AIDS or other fungal infections, the risk of contracting pneumonia is heightened.
This is a contagious disease that may be caused when you breathe the same infected air as another patient with the same disease. It can also follow viral diseases like chickenpox and measles.
 If you wish to discuss about any specific problem, you can consult a pulmonologist.

Common Causes and Symptoms of Pneumonia

Cuts and bruises is a common occurrence in any household. In most cases, they re ignored and left to heal on their own. However, some injuries can take a while to heal. If you think about it, you ll also notice that when you ve injured yourself somewhere, you tend to keep hitting that spot against things and make it worse. Homeopathy is a form of treatment that has negligible side effects and is very effective at speeding up the healing process for bruises and other wounds. Here are a few common homeopathic medicines that you should keep at home to treat bruises etc.

    Arnica: Arnica is very effective when it comes to dealing with deep seated bruises. It can also be used to reduce swelling at the site of the injury. Arnica can be used in pill form or applied in the form of a cream. However, arnica should never be used on an open wound where the skin is cut. In the pill form, arnica can also be used to stop internal or external bleeding.
    Calendula: Calendula can be used to fasten the healing process. Along with bruises, it can also be used to treat ruptured muscles and tendons. When applied topically, it draws out dirt and prevents infections.
    Hypericum: This homeopathic remedy is very useful in treating injuries and wounds that cause nerve damage. It also ensures that a bruise heals from the inside and not only superficially.
    Ledum: Wounds that are caused by a sharp object or formed as a result of painful injections or the after effects of an epidural can be treated with Ledum. It promotes the removal of pus and prevents septic infections.
    Staphysagria: Staphysagria is used to treat sensitive wounds where the tissue is lacerated. In such cases, the sphincters are also found to be lacerated and stretched due to foreign bodies. Staphysagria can also be used to treat extremely painful wounds.
    Phytolacca: This is an excellent remedy for wounds that have a tendency to ulcerate or injuries that cause soreness and can trigger tetanus. Injured fibrous tissue or osseous muscle sheaths can also be treated with phytolacca.
    Bufo: Wounds that cause the area to feel numb and which trigger muscle spasms that leave the patient unable to move the part can be treated with this homeopathic remedy. It can also be used to treat regional hematomas triggered by the rupturing of blood vessels due to the trauma. 

How Homeopathy Helps in Healing Wounds

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