SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

5 Signs of an Unhealthy Heart

The heart is a muscular organ that helps to pump blood through the circulatory system by periodic contractions and relaxations. The heart is one of the most important organs of the body so much so that a single cardiac arrest or a heart attack can lead to fatal consequences. Even so, a heart attack is one of the most leading causes of death in the country. But there are some earlier symptoms that could alert you ahead of time. The following are signs of an unhealthy heart:

1. Sexual problems

Erectile dysfunction (ED) is one of the most predictable reasons for cardiovascular conditions. Today, patients who are diagnosed with ED are also considered as cardiovascular patients. This is because the heart is supposedly not able to pump enough blood to the genital area. In case of women, reduced blood flow can hamper arousal and delay orgasms.

2. Snoring and sleep apnea

If one snores loudly enough to prevent their partner's from sleeping or resort to using earplugs, one may be at a risk of having a weak heart. Restricted breathing during sleep is connected with a host of cardiovascular diseases. Sleep apnea, a condition where breathing stops for a brief span of time, is linked with higher cardiovascular risks.

3. Swollen, sore and bleeding gums

Swollen and bleeding gums are not only symptoms of dental conditions but also of cardiovascular difficulties. Medical experts believe poor circulation of blood arises due to underlying heart conditions. Recent studies are focusing on bacteria that are believed to cause gum disease as well as plaque inside the arteries of the heart.

4. Heart Arrhythmia

Irregular heartbeat or heart arrhythmia is a common sign of a weak heart. It is characterized by both fast and slow beating of the heart. Restricted blood flow to the heart strains the electrical signals that maintain the normal beating of the heart. This is one of the common causes of coronary artery diseases.

5. Chest pain

One of the most apparent signs of coronary artery diseases is chest pain. The cause of the sharp, clutching pain in your chest can be build-up of plaque in the arteries, which could lead to fatal consequences.



5 Signs of an Unhealthy Heart

The term 'chest pain  is a very common term and is usually used in day to day life. Basically, chest pain refers to the pain that may generate in your chest, shoulder and can travel to your ribs, jaws and towards your arms. The feeling of the pain can be sharp or dull, depending on the severity of your condition and cause.

There can be several reasons behind chest pain. You need to conduct a few tests to examine the real cause of the chest pain. It is always advised by health experts to take the symptoms of chest pain very seriously in order to avoid any serious problem in the future. Most of the severe and life-threatening diseases behind chest pain involve lung and heart problems. People having serious heart problems often feel discomfort, followed by pain in their chest area.

Symptoms
Chest pain which is related to any heart disease such as heart attack usually has symptoms like:

Feeling of fullness and tightness in the chest region
Vomiting
Nausea
Burning or crushing pain, which travels from the chest to jaw, hands and back region.
Weakness
Breathing problem
Usually, it is very tough to distinguish whether the pain is associated with a heart problem or not. But generally chest pains which are not related to heart problems involves symptoms like

Sensation in your mouth
Problem in swallowing food
Pain that worsens when you cough
Burning sensation in your chest
Common causes of chest pain

Angina: Angina is a medical condition described as a feeling of discomfort or pain in the chest region. This situation occurs when your heart muscles don't receive blood, which contains rich oxygen. Angina is a symptom of Coronary Heart Disease (CHD). The pain can take place in your shoulder, jaw, neck and arms also.
Lung problems: People with lung disorders can encounter various types of chest pains. But some common causes are:
Pleurisy: It is a type of medical condition, which occurs due to inflammation of the lining of chest and lungs. Due to this, you feel a sharp pain at the time of breathing, coughing or sneezing.
Pneumonia: It is a type of lung infection, which causes chest pain.
Pneumothorax: It is a type of lung disorder, which occurs when a portion of your chest gets collapsed.
Asthma: It is a type of condition, which occurs due to shortness of breath and causes chest pain while coughing, sneezing and breathing.
Gastrointestinal problem: Gastroesophageal reflux disease (GERD) is also a common reason for chest pain such as burning sensation in your heart.
Other causes of chest pain: There are several other reasons of chest pain such as muscle strain, ribs injury, shingles, anxiety and panic attacks. It is always important to visit a physician whenever you encounter any of such chest pain symptoms.

How Chest Pain Related to Heart Problems?

Lifestyle changes and unhealthy habits take a toll on one s physical and mental health resulting in many diseases. One such disease that is growing common is the stroke that occurs due to a sudden interruption of blood supply to the brain. As with any lifestyle disease, the chances of having a stroke can be reduced as well. Knowing the risk factors and taking appropriate measures can prevent you from a stroke attack. 

Read on to know the seven effective ways to prevent you from a stroke.

Opt for a healthy lifestyle: While smoking leads to an increased risk of suffering from a stroke, excessive consumption of alcohol not only triggers irregular heartbeats, but also high blood pressure, which can be a solid reason behind having a stroke. Therefore, leading a healthy lifestyle free from smoking and alcohol can help in preventing strokes.
Manage conditions: Whether it is diabetes or any other kind of illness which directly or indirectly give rise to the risk of having a stroke, dealing with one's underlying conditions is important. In case one is diagnosed with such a condition that can be responsible for a stroke, he or she must make it a point to keep that condition under control.
Lose weight: Obesity is often known to increase the complexities associated with a stroke such as diabetes and high blood pressure. Therefore, for those who are overweight, losing a few pounds can be really helpful in preventing the chances of having a stroke.
Keep blood pressure in check: High blood pressure often causes a stroke, if not controlled. It is referred to as the biggest contributor in causing a stroke by many. Lowering the high blood pressure or bringing it to normal levels can indeed be a great way of preventing a stroke.
Exercise regularly: Exercise not only contributes to lowering the blood pressure, but also helps to maintain body weight while ensuring the overall fitness of the body. Some light hand exercises or regular walking combined with proper diet can do wonders in preventing a stroke.
Have a proper sleep at night: Spending sleepless nights may increase the risk of stroke. Therefore, one must make it a point to maintain the necessary amount of sleep at night that can help in reducing stress and anxiety, while decreasing the chance of heart diseases as well as a stroke.
Never ignore the palpitations: Ignoring the palpitations is the last thing one can want to do, if he or she is willing to prevent the chances of suffering a stroke. Feelings of lightheadedness or shortness of breath, chest pain and abnormal heart beats can be warning signs for a stroke. Therefore, you must pay proper attention to these and deal with appropriate medications.
An otherwise healthy person can stay away from stroke by continuing a healthy lifestyle and following the tips mentioned above. However, if you have suffered a stroke earlier, then it becomes imperative to follow these tips along with supervised medical care.

Stroke - Can You Prevent It From Happening?

Cystic fibrosis is a genetic condition, which primarily affects the lungs and persistence of this condition might lead to severe breathing problems and loss of lung function. If you have inherited two copies of the defective gene from your parents, you are likely to suffer from this disease. Cystic Fibrosis causes a buildup of thick mucus in your lungs and affects other organs such as the kidneys, pancreas and the intestines in your body.

It isn't very uncommon as one out of fifty people in Asia is a carrier of this disease. The disease gets its name from the cysts formed in the pancreas of the sufferer. However, this disease can be detected by testing the quantity of salt present in your sweat. Prenatal testing for Fibrosis is another method to test if your newborn is likely to contract a lung infection.

Complications faced due to cystic fibrosis include:
1. Serious sinus infections
2. Serious damage in lungs due to inflammation and incessant infection
3. Malnutrition
4. Complication in breaking down protein
5. Respiratory tract contamination

If you observe one or more of the following symptoms, you might be suffering from Cystic Fibrosis:
1. Salty-tasting skin
2. Bowel obstruction caused due to meconium ileus (obstruction of the bowels)
3. Mucus amiss in your alveoli
4. Persistent coughing with phlegm discharge
5. Shortness of breath while engaging in a physical task
6. Stunted or measly growth despite healthy lifestyle habits
7. Infertility in males

If you're suffering from cystic fibrosis, there isn't any particular treatment which is recommended due to the varying degrees of it found in people. However, consultation with a medical practitioner and an individualised treatment plan can help you minimise the risks and lead a better life.

Some therapies you can opt for are:
a) Airway clearance: This therapy helps sift the thick layer of mucus around your organs. Some people have also chosen to use the inflatable vest which vibrates around your chest, thereby, thinning and loosening the layer of mucus.

b) Inhaled medicines: Another breakthrough in the field of respiratory medicine, this method requires the patient to sniff a liquid consisting of mist, which is inhaled with the aid of a nebuliser. This method is known to be beneficial for opening airways.

c) Pancreatic enzyme supplements: Along with multivitamins, these specially designed supplements are known to cater to your pancreas with the much-needed nutrients and they need to be consumed with every meal.

Cystic Fibrosis: All You Need to Know

Hypoglycemia is the disease of low sugar level in blood. It primarily occurs when the sugar level is below 4 mmol/L (72mg/dL).

What is hypoglycaemia?
It is the decrease in the blood sugar amount to a certain level. If the disease is identified at an early stage, then the treatment can make the person free of the disease quickly. It affects people having diabetes as well as arthritis, increased blood pressure, high cholesterol and many others.

Early signs of the disease

Weakness
Hungry
Blurred vision
Increased heart rate
Increased sweating
Extreme levels of tiredness
Pale face
Bewilderment
Convulsions
Coma in the last stage
Anxiety
Headaches
Problems with sleeping
Who are the people risk of having this disease?
People who take this three medications have a higher risk of having the disease:

Insulin
Sulphopnylureas (such as glibenclamide, gliclazide, glipizide, glimepiride, tolbutamide)
Prandial glucose regulators (such as repaglinide, nateglinide)
Diabetes medications pose a more significant threat to patients of having hypoglycaemia.

Causes of the disease:

Exercise
Delayed meals
Alcohol drinking
High dose of insulin
Tremendous levels of stress
Deficiency of enzymes
Not balanced hormonal levels
Treatment:

At first, the patient must take a blood test to catch up with the levels of blood sugar
Intake of 15-20 kg of carbohydrates is necessary every day. You can get a stabilized carbohydrate content from a bread slice, a banana and a bar made of cereal.
Drink sugar-filled drinks such as Pepsi, etc. Glucose tablets and juice ease the disease rapidly. The patient can also eat sweets in this case. Take a balanced level of sugar content drinks such as 160 ml of cola or lemonade or 200 ml of fruit juice.
Natural treatment through diet:

Liquorice roots: Cut the roots and boil it. Drink the water every day for controlled sugar level.
Apple- It has magnesium and chromium which regulates the sugar level
Wild yam
Tomatoes
Sunflower seeds
Pumpkin seeds
Gentian Root
Barley
If a person is attacked by seizures. It s not possible to give such medications at that time. At that time a pillow or cushion should be placed below the patients head. The seizure goes away in about 5 min if holds up more time. The person needs to get admitted to a hospital.

Hypoglycemia doesn t have its adverse side effects if captured at an early stage. The person gets recovered with the above-stated home medications. Although slow realization of the disease can take the person to the stage of a comma. The disease engulfs body s maximum energy and few essential body functions also get hampered. But it is treatable with regular natural medications. People having diabetes receives the highest threat of the disease. The sugar levels have to be maintained for proper body working. If the person s blood sugar level is not right, he/she may have the tendency to get hypoglycaemia and hyperglycemia. Having both this disease is the root of having diabetes. It would make the body weak, and the person will crave for more sugar. It will also weaken the nerve cells and tissues of the brain. Weight will be lost gradually which is a terrible sign. Therefore don t be late if you are having this above-stated signs go to the doctor and have the proper diagnosis of the disease.

Hypoglycemia - Signs & Symptoms You Should Not Ignore!

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