SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

Many people know that smoking causes several problems including cancer, heart disease, and respiratory disease. However, there are other diseases occur because of smoking and chewing tobacco. Buerger's Disease is one such disease in which the blood vessels in legs and arms get blocked. This blockage will interfere in blood flow and results in forming blood clots. These clots will affect both legs and
hands.
Buerger's Disease is also known as Thromboangitis Obliterans. It is a type of vasculitis which causes inflammation in the blood vessels including thickening, narrowing, weakening, or scarring.
Buerger's Disease cannot be cured easily. However, by quitting the use of tobacco and smoking, one can limit the symptoms from getting worse. If a person is not able to quit smoking, he/she might end up
suffering from severe tissue damage. One can also even lose toes, fingers, or other parts of the limbs. This is why quitting all type of tobacco or smoking is the only way to treat Buerger's Disease.

What Causes Buerger's Disease?
As discussed earlier, smoking cigarettes or cigars and chewing any form of tobacco is one of the main causes of Buerger's Disease. Still, the exact cause of this disease is unknown, but in most cases of Buerger's Disease, the sufferer has consumed tobacco products. It is an assumption that chemicals present in tobacco, cigarettes, and cigars may affect the lining of blood vessels, causing them to swell. According to experts, the genes in the body may also cause this disease. It is suspected that this disease is caused by an autoimmune response in which the immune system of the body attacks healthy tissues mistakenly. According to this theory, some people are prone to this disease.

Symptoms of Buerger's Disease-
Some of the most common symptoms of Buerger's Disease are:
  Pain in the hands and feet while exercising
  Stiffness due to reduced blood flow
  Pain at Rest
  Skin ulcerations
  Gangrene of the fingers and toes in severe cases
  Numbness, coldness, or tingling of the feet and hand
  Pale, reddish, or blue-tinted hands or feet.

Diagnosis of Buerger s Disease-
There is a set of tests that can diagnose Buerger s disease. Doctors first ask a person about his/her lifestyle, use of tobacco, and symptoms. After seeing a few symptoms, doctors may perform a test to check the blood flow. He may also look for other diseases that cause similar symptoms. Some of the common test to diagnose Buerger s Disease are:


  Allen Test: The Allen test is a blood flow test. In this type of test, patients squeeze their hand into a firm fist, which pushes out blood from hand. The doctor presses the arteries to slow down the
blood flow of the hand. At this stage, the normal color of the skin gets pale. After that, patients open his/her hand and doctors release the pressure from both sides of the wrist one by one. If it takes a longer time to go back to the normal skin color, it may be an indication of Buerger s disease

  Angiogram: It is a type of X-ray that will help to check the blockage of the blood vessels in the legs and arms. In this test, doctor place catheter (thin tube) into an artery to pump the dye. After
that, he takes X-ray images. Doctors may also perform tomography (CT) or MRI scan for clear results.

  Blood Tests: The blood tests will help the doctor to check if there is any other disease that causes the same symptoms as most of the vascular diseases mimics the symptoms of Buerger s
Disease. The doctor may also perform tests to check for diseases like lupus, diabetes, and those that cause blood clots.

Treatment of Buerger' Disease-
Quitting smoking and use of tobacco will help a person to lower the symptoms of this disease. Doctors may also prescribe for pain killers or antibiotics to get rid of the pain in affected areas. If a person finds it difficult to quit smoking, doctors help him/her with the right program and rehabilitation techniques.

Take Away-
Buerger's Disease is one of the rare illness caused by intake of tobacco products, this is why quitting smoking is most important to treat this disease. It is also advisable to consult a doctor as soon as a person identify any of the above symptoms.

All You Need To Know About Peripheral Vascular Injuries!

Carotid artery disease occurs when an oily, waxy substance called plaque builds up inside the carotid arteries. These are arteries that supply oxygenated blood to your brain, face, scalp, and neck.
Carotid artery disease is very serious as it can cause a brain stroke. It, in fact, starts with damage to the inner layer of the carotid artery. To stem this damage your body starts a healing process and this leads to a build up of plaque at the point where the artery is damaged.

When this plaque ruptures, platelets are rushed in and these create an obstruction to the flow of blood to the brain. When the blood supply to the brain is cut off, which happens in carotid disease, the brain cells begin to die causing a stroke. This neural death impairs the parts of the body that these brain cells control. So, you can get paralyzed, become speech or vision impaired, have long  term effects like paralysis or even die due to a stroke.

Causes of carotid disease

Smoking
High cholesterol levels
High blood pressure
High levels of sugar in the blood due to diabetes
What s even more worrisome is that carotid artery disease may not cause any signs or symptoms until the carotid arteries are severely narrowed or blocked. And what usually happens is that a stroke becomes the first sign of the disease.

How scary is that?
So, the next question that comes to the mind is - Can this condition be cured? Let s learn more about management and prevention of the same-

Prevention
Lifestyle changes are key. Since hypertension, uncontrolled diabetes, sedentary lifestyles and imbibing too much fat are all risk factors, taking care of them minimizes the risk of carotid disease and strokes. Heart healthy lifestyle changes that include moderate exercise are a great way to prevent carotid disease.

Treatments
Treatments for carotid artery disease include:

Medicines: Sometimes lifestyle changes do not stem the rot. You need medicinal help. Doctors usually prescribe statin medications to control your cholesterol levels. These lower the bad cholesterol that can narrow your carotid arteries and cause brain strokes and damage. Statins are usually prescribed for people who have:

Heart disease
Those who ve had a stroke
Diabetes
High LDL or bad cholesterol levels
Medicines like Aspirin and Clopidogrel to prevent blood clots are the mainstay treatment if you suffer from carotid disease. They prevent platelets from clumping together inside your carotid arteries and forming blood clots. Apart from these, your doctor may also medicate you for conditions that can damage your carotid arteries and cause strokes. These medicines are for lowering your BP, blood sugar levels, preventing the formation of blood clots anywhere in your body including inside your heart, and preventing and reducing inflammation.

Medical Procedures
These are used to open narrowed or blocked carotid arteries.
The two common procedures are:
Carotid endarterectomy: It s mainly for people whose carotid arteries are blocked 50 percent or more. In this, the inner lining of the carotid artery that is blocking blood flow is removed.
Carotid artery angioplasty and stenting: Here, doctors use a procedure called angioplasty to widen the blocked carotid arteries and restore blood flow to the brain. A stent is inserted into your carotid artery to broaden the lumen. 

High Cholesterol Level - Can It Cause Carotid Disease?

High blood pressure and sex

High blood pressure is a condition in which the pressure of the blood against the artery wall is high enough to cause health problems, including heart disease. No symptoms may be noticed in a person for years but the damage to the blood vessels and to your heart continues. High blood pressure can have an impact on your sex life. Although sexual activity does not lead to any possible threats to your health but high blood pressure can affect the pleasure you would have otherwise derived from sex.

In Men

High blood pressure leads to the wearing out of the lining of blood vessels and causes arteries to narrow and harden that decreases the blood flow. This results in decreased blood flow to the penis. In case of some men, this decreased blood flow makes it difficult for them to achieve and maintain an erection. This problem is called erectile dysfunction.

High blood pressure may also interfere with ejaculation and be a cause for low libido. The medications that are prescribed for treating high blood pressure may lead to this condition.

In Women

Just as in the case of men, high blood pressure results in the decreased flow of blood to the vagina in case of women. This may cause problems like low libido, vaginal dryness, or complexities in achieving orgasm. Sexual dysfunction in women results in stress, anxiety and even relationship issues.



High Blood Pressure and Sex

Asthma is a respiratory disorder, which is characterized by the narrowing down and inflammation of the inner lining of the airways of the lung, resulting in excessive secretion of mucous. The airways are responsible for the passage of air from and to the lungs. Asthma can affect any person of any age group; however, the symptoms of the condition can vary. The symptoms of asthma include severe pain in the chest, coughing and problems in breathing, interruption in sleep due to breathing problems and a croaking sound during exhalation. Asthma, in most cases, tends to be chronic and can exist throughout your life with eventual changes in the nature of attack.

The most common causes of asthma are:

    Common cold and allergies from dust particles, smoke and minute insects might be catalysts for asthma.
    Suffering from severe anxiety might also cause asthma.
    Asthma might occur as a result of physical exercise and as a side effect of some medications such as ibuprofen and aspirin.

As of now, asthma is incurable. But medications can control the symptoms. Homeopathic preparations can also be useful for the treatment of asthma. Some common homeopathic remedies are as follows:
1. Arsenic album: If the symptoms include severe episodes of stress and nervousness, immense thirst but the inability to drink much water, severe attacks at night and intense pain in the upper right portion of the chest, Arsenic Album might be very useful to cure the problem.
2. Nux Vomica: If the attack is primarily caused because of gastric disorders or sudden outbursts of anger along with symptoms of dry cough, headaches and stomach aches, Nux Vomica might be used as a remedial medicine.
3. Carbo Veg: Carbo veg can be recommended if the symptoms include a pale face at the time of attack along with cold feet and hands and an itchy sensation in the larynx.
4. Kali bichromicum and Moschus: If the attacks become worse in the morning accompanied by yellow mucus discharge, the above mentioned homeopathic preparations are recommended.

Asthma: Breathing Made Easy with Homeopathy

Ayurveda is an ancient life science that originated in india. It recognises herbs as medicines and yogic postures as well as lifestyle changes as the supporting factors in its medicinal field. It is called a life science because the basic mode of treatment is done by tweaking one's lifestyle in order to reach the root cause of the ailment, which will be cleared from one's life gradually. Congestion is recognised as the accumulation of too much mucus and fluid in your lungs and is usually born due to an imbalance of the vata dosha, as per ayurveda. This congestion can happen in the nasal or respiratory passages. Let us find out what else ayurveda says about congestion:

Symptoms: the symptoms of congestion include a tickling sensation at the back of the throat as well as the nasal passages, depending on the exact area of the congestion. Also, severe headaches and wheezing along with laboured breathing and tightening of the chest can point at the presence of congestion. In very severe cases, the patient may also complain of blood discharge while coughing, high fever, rashes on the skin, neck stiffness and other such conditions. 

Causes: there are various causes of congestion. While infection, allergy and cold are some of the most common conditions that may cause congestion, it has also been seen that congestion may arise as a symptom of a more serious ailment. Asthma is one such respiratory ailment that causes swelling in the airways, which can give rise to congestion. Also, inflammation of the bronchial tube lining can cause this condition where a greenish discharge happens due to the viral nature of the condition. Pneumonia and tuberculosis are also ailments, which can cause severe and painful congestion. 

Remedies: as per ayurveda, there are many remedies that can help in treating this condition. One can drink herbal tea all day as the anti-oxidants will help in flushing out all those toxins that are causing a painful build-up of mucus and fluids inside. Also, one can use essential oils like eucalyptus oil for inhalation, steaming and even massages. One must take care not to let this oil touch the hair as greying might happen. Yoga and aromatherapy can also be practiced so as to do away with congestion. Also, the patient can add a pinch of salt to a glass of warm water in order to do a saline water gargle which will eventually clear the air passages. 

Taking care of one's diet is one of the most important parts of any treatment in ayurveda. Ingesting warm liquids like milk and warm food can help in loosening and removing the mucus build up.

Ayurvedic Medicine for Chest Congestion Treatment

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