Cancer has been regarded as one of the most deadly diseases. It is a non-communicable chronic disorder, caused by uncontrolled growth of cells in the human body. Every year over 7 million people succumb to this disease globally and over 12 million people are diagnosed with cancer. Indian Council of Medical Research (ICMR), estimated that India will observe over 8 lakh deaths and over 17 lakh new cancer cases annually by the year 2020. The survival expectancy of a cancer patient depends upon the stage of diagnosis.

There are some forms of cancer which show any noticeable symptoms only in the final stage while there are certain other subtle symptoms which if paid attention to might save a life.
Some common signs of cancer:

Unexplained weight loss: This is one of the earliest noticeable symptoms of cancer and is particularly common in patients of lung and breast cancer. Weight loss has been observed in over 40% of cancer patients at the time of diagnosis. Losing over 10% of body weight in a span of 6 months or less could be a cause of concern.
Wheezing: This is associated with lung cancer, which is also the most common form of cancer. When the airway in the lungs is pressed or narrowed by a tumor, it creates a wheezing sound while breathing.
Frequent infections: Frequent infections and fever may indicate that something is not right with the internal organs of the body. This could be because of cancerous conditions such as leukemia or lymphoma. 
Loss of appetite: Cancer impacts the metabolic process of the body, hence often leads to a loss of appetite. This is particularly a symptom of colon, stomach, ovaries and pancreatic cancer. 
Blood in stool/urine: Traces of blood while passing stool or urine could be a symptom of cancer. Though, this could be attributed to many other infections and conditions as well.
Chronic cough: Flu and cough along with symptoms like chest pain, hoarseness, weight loss and fatigue could be because of lung cancer.
Night sweats: Though night sweat could be attributed to many more reasons, it is also one of the many early warning signs of cancer.

Early Warning Signs Of Cancer That We Often Ignore!

Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

In case you have a concern or query you can always consult an expert & get answers to your questions!

CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

Cancer like most other diseases has the best rates of recovery with early detection and intervention. As there are no regular health screenings for blood cancer, only the awareness about the early warning signs can save your life. November is designated as the Lung Cancer Awareness Month, to ensure every individual is equipped to fight against lung cancer right from the start. Here are 4 vital facts you must know to win your fight against blood cancer.
Lung cancer is also known as pulmonary carcinoma or cancer of the lung. It occurs when DNA mutations develop in the cells/ tissues of the lungs leading up to uncontrolled growth in the tissues of the lung. By far, it is known to be the most common cancer in Asia.

1. Type: lung cancers can present as one of the following types: 

Non-Small Cell Lung Cancer (NSCLC): Most common type of lung cancer and constitutes nearly 85% of all lung cancers. The sub-types of NSCLC are as follows:
Large cell carcinoma
Squamous cell carcinoma (SqCC) (Epidermoid)
Adenocarcinoma   accounts for majority of the NSCLC.
Small Cell Lung Cancer (SCLC): It is also known as oat meal cancer and tends to spread (metastasize) quickly. This constitutes about 15% of the lung cancers.
Mesothelioma: It is a rare cancer that develops in the mesothelial cells of the pleural or peritoneal surfaces. It usually arises in the pleural membrane lining the lungs, known as pleural mesothelioma. One that arises from the peritoneum is called the peritoneal mesothelioma and the one that arises from the pericardium is known as pericardial mesothelioma. Lastly, it can also arise from the tunica vaginalis known as testicular mesothelioma. People working with or prior exposure to asbestos are mostly at risk of developing mesothelioma. The latency period between time of exposure and development of mesothelioma can be somewhere between 20 to 40 years. Maximum of the patients who develop mesothelioma are men.
2. Gender: It affects the male populace predominantly. It is more common in men than in women and in those of lower economic status. However, the incidence of lung cancer, in women too, is on the rise of late.

3. Etiology: Cigarette/ Tobacco smoking remains the most important cause of lung cancer accounting for 85   90% of the cases. Incidence/ risk is proportionate to the number of cigarettes smoked irrespective of the age. Also, environmental toxins including smoke from burning black tar, exhaust gases from automobiles etc. too contribute actively to various lung diseases including cancer. People working in asbestos manufacturing factories who are exposed to asbestos dust are also likely to get lung cancer. Tuberculosis too is an additive risk factor. Again, people who have received ionizing radiation especially to treat Hodgkin Lymphoma or other malignancies also run the risk of developing lung cancer. Above-mentioned causes apart, genetic factors may also play a role.

4. Features: Lung cancer clinically presents in the following ways mainly. Signs & symptoms of malignant mesothelioma are as enumerated below

Difficult/ labored breathing (Dyspnea)
Chest pain
Palpable chest wall mass
Discordant chest wall expansion
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Night sweats
Signs & symptoms of non-small cell lung cancer (NSCLC) are as enumerated below. Majority of patients are symptomatic at diagnosis

Chronic cough
Difficult/ labored breathing (Dyspnea)
Chest pain
Blood stained sputum (Hemoptysis)
Hoarseness
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Weakness
Bone pain
Pleural or pericardial effusion
Superior vena cava syndrome
Brachial plexopathy
Neurologic pain
Hypercalcemia of malignancy
Signs & symptoms of small cell lung cancer (SCLC) are as enumerated below

Symptoms as per the points 8   18 depicted above for NSCLC are applicable for SCLC as well. Additionally, patients suffering from SCLC may have:

Fever associated with chest infections like bronchitis/ pneumonia that refuse to go away or keep coming back
Horner syndrome
Paraneoplastic syndromes including encephalitis/ sub-acute sensory neuropathy, hyponatremia, acromegaly, cancer associated retinopathy, ectopic corticotropic syndrome etc all.
5. Screening: is generally recommended for asymptomatic/ symptomatic populations as surveillance for high-risk individuals   who are either current or former smokers (quit smoking within the last 15 years) have at least a 30 pack-year smoking history and those who do not have any prior history of lung cancer. The goal of screening, as usual, is to be able to detect & diagnose lung cancer at an early stage which is potentially curable. It is mostly radiologic with a low dose helical computed tomography (CT) scan being more effective in detecting early-stage lung cancer than a chest radiograph can.

6. Diagnosis: Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for an accurate diagnosis. Following are the diagnostics employed mainly:

Blood: Hb may be low, TLC, ESR and polymorphs increased. Adenocarcinomas are likely to express thyroid transcription factor 1 (TTF-1) or carcinoembryonic antigen (CEA). On the other hand, mesotheliomas are likely to express Wilms Tumor -1 (WT-1) protein and Calretinin.
Imaging: Thoracoscopy, Bronchoscopy, X-Ray, CT Scan etc all. Positron Emission Tomography (PET) / CT scan and Magnetic Resonance Imaging (MRI) scan help detect metastasis if any.
Biopsy: It clinches the histologic diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.

8. Prognosis: Preventive measures, earlier diagnosis and right early treatment are key for effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for early-stage lung cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. The primary determinant of prognosis in NSCLC is the stage at which the cancer is diagnosed. For non-metastatic cancers, however, it is the nodal status that determines the stage and hence the prognosis.

9. Prevention: Rightly said, prevention is always a better choice. Cigarette smoking is to be avoided by all means as it is the single major cause of lung cancer. Even exposure to cigarette smoke (passive or secondhand) is also an established cause of lung cancer and is known to increase the risk of lung cancer in non-smokers as well. Preventing exposure to secondhand smoke can be helpful in decreasing the incidence and mortality of primary lung cancers. Above-mentioned apart, other important risk factors such as exposure to ionizing radiation, environmental carcinogens like smoke from burning black tar, exhaust gases from automobiles, outdoor air pollution, and occupational exposure to asbestos, arsenic, beryllium, nickel, cadmium, chromium etc all too are known to increase the risk for lung cancer and mortality thereof. In fact, cigarette smoking is known to potentiate the effect and hence the lung cancer risk of many of the above-mentioned carcinogens, multi-fold, in smokers. Thus, either eliminating or reducing the exposure to the above-mentioned carcinogens can lead to a decrease in the risk of lung cancer and incidences thereof. Furthermore, randomized clinical trials indicate that high-intensity smokers (only) who take supplementation of beta-carotene have an increased risk/ incidence of lung cancer. Vitamin E supplementation, on the other hand, does not affect the risk of lung cancer as indicated by the trials. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

Lung Cancer Awareness Month - Lung Cancer In Nutshell!

According to a major study that provides a connection between height and cancer, it is stated that taller people are more prone to developing cancer. Research has found that the risk of developing any kind of cancer in women rises by 18% for an increase of every 10 cm in height. In men, the risk rises by 11%, even though height is not as major a factor as are obesity, smoking and a bad, unhealthy diet.

Several reasons have been put forward for the above statement. One of the reasons is that the number of body cells in taller people is more than people with average height. This leads to an increase in the number of cells which could potentially turn malignant.

While individually analysing the impact of height on different cancer forms, it was found that the highest increase in risk was in skin cancer (30% for every 10 cm increase in height), while a 20% increase was noted in taller women developing breast cancer.

Development of cancer in regions including the colon and rectum is known as colorectal cancer. Long legs have been surprisingly associated with this form of cancer. In comparison with shorter people, it was reported that taller people had a higher risk percentage of developing colorectal cancer. Two hypotheses regarding the formation of colorectal cancer have been developed. One hypothesis is that taller people have longer colons, which in turn result in more surface area where colon cancer can develop. The other hypothesis is that taller people experience increased levels of growth hormones. These particularly affect the length of their legs. The growth hormone called 'insulin-like growth factor 1' is increased during puberty and is considered to be a risk factor for colorectal cancers occurring at later stages.

Being Taller Increases Your Risk of Cancer!

One of the most significant glands in the male reproductive system is the prostate gland, which is responsible for carrying urine from the bladder. It is located right under the bladder and helps in production of semen which contains sperm.
Prostate cancer is a slow growing form of cancer that is rarely seen in men below the age of 50. It may occur due to both, genetic and environmental factors. Here is a list of measures that can help in preventing this ailment.
Food Intake and Weight: Apart from age, the major factor that contributes to the risk of prostate cancer includes food and weight. Doctors suggest that bringing down your intake of calcium and fat that comes from red meat and excess dairy can help in preventing the onset of this ailment. The calcium intake should not go beyond 1,500 mg per day, which is why doctors will usually ask you not to have supplements. Cooked tomatoes with olive oil as well as cruciferous vegetables including broccoli and cauliflower should be included as a vital part of one's diet, while fish should be taken regularly as it is a source of healthy or good fat like Omega-3 fatty acids. In general, you should have fewer calories which should be matched up with ample exercise so that a healthy weight and balance is maintained.
Stress and Blood Pressure: Stress and anxiety are also major reasons that contribute to the onset of this disease. One will need to see a doctor about high blood pressure, especially the kind that is triggered by stress and causes hypertension. Also, you must control your cholesterol and stay out of depression to ensure that your risk of developing prostate cancer reduces. Also, having these conditions along with prostate cancer makes the survival chances that much lower. So, you must get the right medication and treatment for these conditions as well.
Lifestyle: One will need to quit smoking, that can cause a number of ailments including prostate cancer. Also, drinking alcohol in moderation is required in order to have a healthier lifestyle and cut the chances of developing such ailments.
Screening: While your diet and other aspects may be right, there is still a great chance of developing prostate cancer, especially if anyone in your family has been afflicted with this condition in the past. Therefore, it is recommended to get an annual screening done so that you eliminate the chances of finding it out late, and can check the growth of any anomalies as soon as they take place. Getting regular checks ups done and getting diagnosed for the problem when the earliest symptoms begin to show are both crucial for prostate cancer.


Prevention Of Prostate Cancer

If you are suffering from breast cancer, it is recommended that you undertake Ayurvedic measures for an effective and natural treatment. Breast cancer is a form of cancer that occurs in the cells of your breasts. The breast cells undergo abnormal growth and go out of control. This form of cancer is likely to occur in both women and men, although it is most common in women. A lot of breast cancer cases start from the ducts or lobes, while others start from the cellular lining of your milk ducts.

Ayurvedic view
According to the principles of Ayurveda, your body is based on the tridoshas, which include vata, pitta, and kapha.

An imbalance in these doshas can lead to diseases and disruption in your health. Cancer occurs when an imbalance of all the three doshas is experienced.
An improper diet and lifestyle account for being the primary reason for this imbalance in doshas, leading to breast cancer.
Your digestive fire is also affected, which leads to the accumulation of toxins, thereby blocking all the channels of your body.
All these factors are collectively responsible for the development of breast cancer.
Ayurvedic treatment

Ayurvedic treatment for breast cancer is very effective because of its natural approach.
Without the use of any chemicals and radiation, you get efficient management by using Ayurvedic remedies for breast cancer.
Your body functioning is enhanced without the concern of any negative effect on your health.
Several Ayurvedic herbs are used for breast cancer treatment. These herbs help in controlling the abnormal growth of breast cells, and in the later stages of breast cancer, these also help in reducing pain.
The herbs play an important role in preventing the condition from spreading to other organs.

Ashwagandha

This powerful Ayurvedic herb contains natural rejuvenating properties for your body.
It also helps in eliminating stress, weakness and fatigue, which are associated with breast cancer.
Curcuma

This effective Ayurvedic herb contains several medicinal properties.
It is an antioxidant and helps in reducing free radicals from your body. This is beneficial for an improved health and immunity.
The herb is capable of dealing with toxins and infections, and is super effective in treating malignant cancers.
Kanhnaar Guggul

This is an Ayurvedic product, which is obtained by mixing several herbs such as amalaki, haritaki, ginger, kachnar bark and a lot more.
This is effective in maintaining healthy tissues and cells. It also stops the abnormal growth of cancerous cells.
It is important for you to visit a licensed and experienced Ayurvedic practitioner for getting the best Ayurvedic remedies for breast cancer treatment. This will ensure that you get the most effective remedies, based on your condition.

Breast Cancer - Can Ayurveda Help You Treat it?

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