Grading of brain cancer is entirely different as compared to the staging of other cancers in the body. Cancer in the breast, lung, colon etc. are staged depending on the possible spread, location of a tumor and lymph node involvement etc. However, brain tumors are graded based on the aggressiveness of the tumor cells under a microscope. The resect ability and the grade of the tumor cells guide a doctor on the treatment decisions. The decision of a brain surgery depends on factors such as the location, spread of a tumour and the general health of the patient.

Types of Brain Tumor Grading:

Grade 1 tumor- These sets of tumors are medically known as the juvenile pilocytic astrocytoma and subependymoma. They are slow growing and non-invasive. There is a likelihood of the patient getting cured with surgery.
Grade 2 tumor- These are brain tumors that do not possess dead cells as part of the tumour. But, they do portray a lot of abnormal cells. Tumors of this type can be categorized under oligodendroglioma, astrocytoma, and ependymoma.
Grade 3 tumor- Tumors of this type are graded based on the cell type of the cancer cells. For instance, an anaplastic astrocytoma is a grade 3 tumor that has no dead cells but possesses dividing cells. In contrast, anaplastic ependymoma and anaplastic oligodendroglioma are grade 3 tumor cells that have dead cells in them.
Grade 4 tumor- Tumors of this type are referred to as glioblastoma. The tumor cells are actively dividing, the growth of blood vessels is witnessed and areas of dead tissue keep expanding.

Treatment options:
Surgery- If the location of a brain tumor is such that it is accessible to a surgeon, the latter goes ahead and removes most of the tumor if not the whole. If, however, the brain tumor cells are placed very near to the surrounding very sensitive brain tissues, a doctor might remove a small portion of the tumor to curb its growth.
Radiation Therapy- This mode of treatment uses high energy X-ray beams to kill targeted cells of the brain. External beam radiation usually targets a small area of the brain. A whole brain radiation, on the other hand, is usually employed when a tumor has spread to most parts of the brain. Radiotherapy is now so evolved that it is highly targeted to tutor cells that kills cancer and spares normal brain .
Chemotherapy- Chemotherapy employs drugs to kill cancer cells. Chemotherapy can either be taken in the form of an IV or in the form of pills. The dosage of chemotherapy is decided based on the concentration of cancer cells, spread frequency, platelet count of the patient etc. The most common chemotherapy drug that is prescribed by doctors to fight cancer cells is temozolomide.

Brain Tumor - Stages and Treatment!

Are you aware of the link between air pollution and cancer? Air pollution refers to the mixture of several harmful substances, which lead to various serious health hazards on exposure. The primary sources of air pollution are man-made, including fumes from automobiles and the smoke from burning fuels. Desert dust, radon gas, and several other natural sources of air pollution are equally dangerous. Air pollution is classified into outdoor and indoor air pollution. It is highly associated with increased risks of developing cancer. Smoking is considered to be one of the major agents, which pollute the air and increase the chances of cancer to a large extent.

Outdoor air pollution

Outdoor air pollution is strongly linked with cancer development.
As every person is exposed to some form of air pollution, it has a more harmful effect on the whole population across the globe as a general threat.
A certain part of outdoor air pollution referred to as PM 2.5, or solid dust particles, are highly responsible for the development of cancer.
The chances of cancer increase with the increase in PM 2.5 levels in the air.
Indoor air pollution

There are several sources of indoor air pollution that are closely associated with an increased risk of cancer.
The sources include fuels used for heating homes and for cooking, radon, and tobacco smoke.
Second hand smoke is another harmful indoor air pollutant that causes cancer.
Second hand smoke

Secondhand smoke increases the risk of cancer development, along with the risk of developing other diseases such as stroke and lung disease.
A lot of people all over the world get exposed to second hand smoke.
A lot of deaths occur due to cancer because of second hand smoke exposure which is common every year, all over the globe.
Radon

Radon is a natural radioactive gas, which is associated with increased risks of developing lung cancer.
It is found at low levels outdoors. It may also build in high concentrations indoors.
Although radon exposure does not pose a huge threat for cancer, a lot of radon-associated cancers develop due to exposure to radon, along with tobacco smoke.
Benzene

This is a flammable liquid having no color and with a sweet odor.
It is closely associated with the development of leukemia and cancers affecting other cells of the body.
Cigarette smoking and tobacco smoke are major cancer causing elements that are found in the air commonly. Both of these are quite harmful. It is recommended that you not only quit smoking, but also keep away from passive smoking.

Pollution and Cancer - How They Are Related?

Neurological disorders may creep in due to many reasons. It may be due to degenerative diseases, accidents, other health conditions, birth defects or genetics. The most common form of disorder occurs due to non-functional brain cells in some parts, and loss of myelin sheath in neurons, which protects the nerve signals in their complete transfer from origin to destination. These losses are irreparable, but further degeneration can be avoided with Ayurveda. Panchakarma, the branch of Ayurveda, which deals with detoxification of the body and mind, specially helps. Over a period of time, it can bring back the lost sensation in nerves. Yoga, pranayama and Ayurvedic treatments lead to recovery and relief to a huge extent.

Important facts about Panchakarma
There are 3 important steps in Panchakarma, which are followed one after another to get the result. The main objective of Panchakarma is to detoxify the body. Virechanam, vamanam, sneha vasti, nasyam and kashaya vasti are the 5 folds in Panchakarma.

Poorvakarma or preparing the body, followed by Abhyangam or massage, followed by Elakizhi or herbal paste massage, and finally podikizhi, or steam bathing makes the body ready for receiving further treatments.
Njavara Kizhi is the special treatment done in Panchakarma where the body is given a rice bolus massage to improve the joint and neuro functions.
What is Njavara Kizhi?
Njavara is a variety of rice, which is specially used for Ayurvedic treatment and massages. In this treatment the rice is made into a pudding by boiling it with milk. This pudding is then made into boluses. The boluses are filled in muslin cloth, and then using these muslin bolus dabs, the whole body of the patient is massaged. This full-body massage has excellent effects on neurological and joint functions. The deep tissues within the body are rejuvenated. The treatment is carried on for 45 minutes to 60 minutes by therapists or experts. Another form of the treatment requires the rice to be made into a paste, and then the paste is applied all over the body. But this is more preferred for beautification.

Other effective therapies
Siro Vasti, Kati Vasti, Ela Kizhi and Nasyam are all different forms of Panchakarma treatment, which detoxify the body and mind and rejuvenate the body and nerve functions. But these treatments cannot be conducted on the body on your own. You need a masseur who must be a specialist in Ayurveda to do this for you. Hence contacting Ayurvedic clinics, doctors or experts would be the best to start the treatment.

Neurological Disorder - How Panchkarma Therapies Can Help?

Cancer has been regarded as one of the most deadly diseases. It is a non-communicable chronic disorder, caused by uncontrolled growth of cells in the human body. Every year over 7 million people succumb to this disease globally and over 12 million people are diagnosed with cancer. Indian Council of Medical Research (ICMR), estimated that India will observe over 8 lakh deaths and over 17 lakh new cancer cases annually by the year 2020. The survival expectancy of a cancer patient depends upon the stage of diagnosis.

There are some forms of cancer which show any noticeable symptoms only in the final stage while there are certain other subtle symptoms which if paid attention to might save a life.
Some common signs of cancer:

Unexplained weight loss: This is one of the earliest noticeable symptoms of cancer and is particularly common in patients of lung and breast cancer. Weight loss has been observed in over 40% of cancer patients at the time of diagnosis. Losing over 10% of body weight in a span of 6 months or less could be a cause of concern.
Wheezing: This is associated with lung cancer, which is also the most common form of cancer. When the airway in the lungs is pressed or narrowed by a tumor, it creates a wheezing sound while breathing.
Frequent infections: Frequent infections and fever may indicate that something is not right with the internal organs of the body. This could be because of cancerous conditions such as leukemia or lymphoma. 
Loss of appetite: Cancer impacts the metabolic process of the body, hence often leads to a loss of appetite. This is particularly a symptom of colon, stomach, ovaries and pancreatic cancer. 
Blood in stool/urine: Traces of blood while passing stool or urine could be a symptom of cancer. Though, this could be attributed to many other infections and conditions as well.
Chronic cough: Flu and cough along with symptoms like chest pain, hoarseness, weight loss and fatigue could be because of lung cancer.
Night sweats: Though night sweat could be attributed to many more reasons, it is also one of the many early warning signs of cancer.

Early Warning Signs Of Cancer That We Often Ignore!

Trigeminal neuralgia is specified by the condition of a chronic pain that influences the trigeminal nerve. This nerve transfers sensation from one s face to his/her brain. If a person is suffering from trigeminal neuralgia, then a gentle stimulation of face (sourced from brushing teeth or applying makeup) might generate a fright of agonizing pain. The affected person might experience short and mild attacks initially. However, the trigeminal neuralgia might progress and generate more-frequently and longer attack of severely critical pain. Women get affected by this situation more than men get and it is more prominently occur in individuals older than 50 years.

Trigeminal neuralgia does not mandatorily mean that you need to experience a lifelong pain. Various types of treatment alternatives are available and so doctors can usually handle the particular condition effectively by taking help of injections, medications or surgery. Various types of triggers might cause the pain regarding trigeminal neuralgia, such as eating, drinking, shaving, brushing teeth, touching face, smiling, washing face etc.

Symptoms

The symptoms of trigeminal neuralgia might comprise of one or more patterns and some of these are described below:

Sequences of serious, jolting or shooting pain that might generate as an electric shock
Spontaneous pain attacks or attacks stimulated by different activities like face touching, speaking, chewing, or brushing teeth. Pain attacks last from a few moments to some minutes.
It is not a comprehensive list because Trigeminal neuralgia hosts various other symptoms as well. If a person feels facial pain, specifically recurring or prolonged pain or if the person does not get relief through the utilization over-the-counter pain relievers, then that person must consult a doctor.
How does Radiofrequency Ablation treat Trigeminal Neuralgia?
Trigeminal Neuralgia is a chronic and painful condition that involves the trigeminal nerve. There are two separate trigeminal nerves on both sides of the face, which carry the sensations like pain from the face to the body. Each nerve has three branches- forehand, midface and chin and trigeminal neuralgia can cause intense pain in any of these areas.

Causes-

This occurs when the trigeminal nerve functioning is disrupted. When the blood vessel/artery and the trigeminal nerve at the base of your brain come in contact, it puts pressure on the nerves and causes pain.
It also occurs as a result of ageing or multiple sclerosis
A disorder that damages the myelin sheath protecting the nerves can trigger pain
Sometimes pain occurs from tumors, which compresses the trigeminal nerves
Surgical strokes, facial trauma or strokes can also be the root cause of excruciating pain
Triggers-

Shaving
Touching your face
Eating and drinking
Putting on makeup
Brushing
Washing your face
Symptoms-
The pain can be mild and for a shorter duration or it can happen frequently for longer durations. Some experience the pain in cycles where it can come and go for days or even for weeks. Gradually the intensity of the pain lessens.

Cure by Radio-frequency Ablation
The treatment of trigeminal neuralgia is often a challenging process in clinical practice. When medicines do not prove as effective, surgery is the desired option.

Procedure-

After applying local anaesthesia, the Pain Specialist carefully inserts a needle through the corner of your mouth to reach the trigeminal nerve
The doctors then wake up the patient after stimulating the nerves and ask them to feel the stimulation at the same place where they undergo pain. This confirms their targeted location
Once you fall asleep again, the Pain Specialist uses radiofrequency heat to injure the nerve enough to create numbness and removes the pain
How Effective is Radio-frequency Ablation?
The pain is cured almost in 98% of the patients. 50% of patients report recurrence of pain after about two years. Hence the procedure can be repeated in the same patient if necessary.

Trigeminal Neuralgia And Radio-Frequency Ablation - What Causes It?

Brain tumor refers to the development of unusual cells in the brain or around the nearby tissues and structures. Pediatric Brain Tumor means the development of these unusual cells in the brain of children. There are two types of brain tumors: Benign or non-cancerous and malignant or Cancerous. Tumors like ependymoma and medulloblastoma are quite common among children. The treatment of the tumor is determined by its severity, type, location, age, and overall health of the child. The treatment of Brain Tumor in children is different from the adult s treatment. One should ensure to consult with the pediatrician with the specialty in cancer and neurology. Brain Tumors in children are Primary Brain Tumors that develop in the brain or nearby tissues. This Primary Brain Tumor develops when the usual cells have DNA mutations or alterations. The alterations in the DNA permit the cells to develop and distribute or split with an increased rate and destroy the healthy cells. This leads to the development and collection of unusual cells forming a tumor. In most Primary Brain Tumor cases, the cause is not clear. Children with a family history of the genetic syndrome and Brain Tumor are more prone to the problem.

Symptoms-

The symptoms of the Pediatric Brain Tumor depend upon the severity, location, and type. There are a number of symptoms that are really common and are shared by other diseases. Other than this, there are symptoms which are possibly the signs of Brain Tumor among children. Adults and parents should consult a doctor if they find their children having the symptoms and signs for an unusual time.

Hearing issues

Frequent and severe headache

Fuller fontanel (soft spot) on the baby s skull

Vomiting or nausea

Behavior changes

Seizures

Sudden vision problems like double vision

Abnormal or strange eye movement

Increased heaviness or pressure in the head

Irritability

Slurred speech

Difficulty in swallowing

Weakness

Loss of appetite

Drooping on one side of the face

Difficulty feeding in babies

Loss of sensation on one side of the body

Imbalance or difficulty in balancing

Difficulty in walking

Diagnosis-

The diagnosis for the Pediatric Brain Tumor includes many lab tests. The doctor may initiate with some neurological examination like hearing, vision, reflexes, balance, and coordination. Any abnormality in these tests will lead to further examinations. There are some imaging tests that are used to determine the size and location of the tumor in the brain. These tests include MRI (Magnetic Resonance Imaging), PET (Positron Emission Tomography), and CT (Computerized Tomography). After the confirmation of the presence of a Brain Tumor, the specialist will further move to the Biopsy. It includes the removal of a sample tissue for analysis or testing. The type of biopsy that will be performed on the patient depends upon the location of the tumor. Other than the biopsy, the tumor tissue can be examined for molecular basis and genetic mutations. After that, Drug therapy can be designed according to the individual s requirements. It is important for the doctor and the patient to know if the tumor has been spread through cancer in other parts of the body. If it is true, then the doctor will perform more tests and examinations to know the root and initial location of cancer for further treatment.

Treatment-

The treatment of the Pediatric Brain Tumor is determined by the severity, location, size of the tumor, and age and health of the child. There is a number of treatments available with modern technology but their usage depends upon the patient s requirement.

Surgery that is used when the location of the tumor is approachable via surgery. When the brain tumor is small, it can be completely removed by the surgery. But when the tumor tissues are located nearby sensitive areas of the brain, then the surgery becomes risky and maximum tumor tissues are tried to be removed through surgery. The risk of the surgery depends upon the location of the tumor. An example can be vision loss if it is anywhere near the nerves connected to the eyes.

Targeted Drug Therapy helps to destroy the abnormalities of the cancer cells resulting in the destruction of the cancer cells.

Radiation therapy is used to kill the tumor cells by using high-energy beams. Radiation therapy can either be given by an external machine (external beam radiation) or in exceptional cases, radiation is positioned within the body (brachytherapy) near the tumor.

Chemotherapy includes the consumption of drugs to destroy the tumor cells. These drugs can be consumed in tablet form but for children, the drugs are mostly injected (intravenous chemotherapy).

Stereotactic Radio Surgery includes various radiation beams to perform extremely focused radiation therapy to destroy the tumor cells located in a small part.

Proton Beam Therapy carries higher targeted radiation doses to the tumor cells with minimum exposure of radiation to the healthy cells and tissues. It decreases the chance of development of fresh cancer cells.

Take Away-

Pediatric Brain Tumor is the development of unusual cells in the brain or around it. Although this is a life-threatening problem, however, with advanced technology, it can be treated successfully. There are no specific causes discovered by specialists but genetic mutations and family history cause it. The symptoms can be really common like headache and nausea but can also be specific like difficulty in coordination, reflexes, speech, and many more. The timely diagnosis and treatment can give a new life to the child and reduces the chance of development of fresh tumor cells in the future.

Pediatric Brain Tumor - Know In Detail About It!

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