Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

Often, early stages of kidney diseases do not come with specific signs and symptoms and most people will remain unaware of their condition. However, certain symptoms may be perceived that may indicate that a person is suffering from early stages of kidney failure. When you are diagnosed with kidney failure (also known as renal failure) in the initial stages, certain measures can be taken to retard the progression of the renal disease. This can also help reverse the condition and improve the quality of life of the patient. On the basis of a typical cause, the symptoms of kidney failure are grouped into specific categories that are given below. If you notice any of the specified renal failure symptoms, it is recommended to immediately fix up an appointment with your doctor and get your diagnostic tests done. 

Symptoms of Renal Failure from the accumulation of waste products in the body: 

Metallic taste in mouth 
Nausea and vomiting 
Facing difficulty in concentrating 
Loss of appetite 
Aversion towards meat (protein aversion) 
Itching or pruritus 
Symptoms of Renal Failure from the accumulation of fluid in the body: 

Dyspnoea or shortness of breath (this happens due to the accumulation of fluid in the lungs).
Swelling is seen in the feet, hands or face. 
Symptoms of Kidney Failure from damage to the kidneys: 

The amount of urine production changes, though it is not a reliable sign Haematuria or blood in the urine (usually in microscopic quantity). 
Frothiness or foam in the urine (usually happens when protein is present in the urine). 
Symptoms of Kidney Failure due to decreased blood production (anemia): 

Dyspnoea or shortness of breath. 
Fatigue Weakness. 
Confusion If you happen to feel cold all the time. 
The following diagnostic tests will be performed by your doctor in order to determine whether the symptoms are the manifestation of a kidney failure or not: 

Urine analysis - In this test, a sample of your urine is tested to find traces of blood, white blood cells or proteins which may indicate a problem in kidney function. 
Blood Tests - This includes tests for BUN and creatinine in the blood which are usually removed from the blood if the kidneys function properly. 
Actions must be taken when you show signs and symptoms of kidney failure: 

It is common that the symptoms of early renal failure are not always prominent, but if any of the above symptoms are witnessed, it is recommended to met a physician to determine whether they are caused by a kidney disease. You can pen-down the symptoms that you feel are related and bring it to the doctor when you fix up the next appointment. It is essential to know about your disease at the earliest as it will give you time and the ease of taking measures to retard the damage process and will decrease or delay the probability of undergoing dialysis or kidney transplant.

Kidney Failure - What Should You Know About it?

Needless to say, your kidneys play an incredibly important role in filtering waste from your blood, and therefore maintain healthy functioning of the body. Blood pressure, production of red blood cells, and electrolyte balance, all of these are regulated by the proper functioning of the kidneys. Kidney failure causes too much build-up of waste nitrogen products,acids and/or excess fluid,which causes major cardio respiratory problem to the patient.
Symptoms-

Shortness of breath 
A reduced amount of urine
Swelling of your legs, ankles, and feet
Excessive drowsiness or fatigue  
Confusion
persistent nausea
Pain or pressure in your chest
Seizures
Coma 
Inability to properly remove potassium that runs in the bloodstream can lead to irregular heartbeat and ultimately, death that is sudden and unforeseen.

How can it be treated?
The causes of kidney failures are many and the key to treat them is to correct the underlying cause first. Chronic kidney disease, however, has no cure. Treatment generally comprises measures that aid in controlling symptoms and signs, reduce complications, and slow down the progression of this disease. Despite efforts to treat the cause, the condition might keep worsening and there is little to guarantee the fact that complications will not arise. This is precisely why it is of utmost importance to opt for examinations at regular intervals so that you may ascertain if your disease has remained stable or worsened.

End-stage of Kidney disease 
In the case that your kidneys are unable to keep up with fluid and waste clearance as is normally expected, then there s a good chance that you have developed a near-complete or complete case of kidney-failure, and are afflicted by end-stage kidney disease. If this is indeed the case, then you have two options to resort to:

Dialysis: This helps remove the extra waste products that the kidneys fail to do. In haemodialysis, fluid and waste filtering takes place with the aid of a machine that drives these excesses from the blood. In peritoneal dialysis, catheters are employed to rid the body of the accumulated waste products.
Transplant: Kidney transplants involve a surgical placement of a healthy kidney in your system from a compatible donor, either living or dead. Medications will be a necessity since the body has to be prevented from rejecting this new organ.
You may also opt for treating the condition with conservative measures in case you don t want to resort to the aforementioned procedures.

When we talk about health, the kidneys are rarely spoken of. These unsung heroes are responsible for filtering waste out of our bodies and ensuring that only clean blood flows through our system. The kidneys are a pair of small, bean-shaped organs located at the back of the abdomen. Along with removing waste from the blood, the kidneys also balance electrolytes and control the fluid balance in the body. Thus, keeping the kidneys healthy is as important as keeping the heart and lungs healthy.

Kidney stones are the most common condition that can affect these organs. Other conditions that can affect the kidneys include inflammation of the kidneys, renal failure, nephrotic syndrome and cysts. Thankfully, keeping the kidneys healthy is easy. Here are a few things you can do to improve the health of your kidneys.

Drink plenty of water: Keeping your body hydrated is crucial to kidney health. Ideally, a person should drink a minimum of 8-10 glasses of water a day. Water helps control the production of aldosterone- a hormone that regulates blood pressure- by the adrenal glands and helps the kidneys retain enough water and sodium to balance blood volume levels. If the kidneys do not get enough water, the adrenal glands are stressed into increasing blood pressure levels.
Limit consumption of caffeine: We drink caffeine in many ways- sodas, coffee, tea etc. While caffeine may act as a stimulant and keep you focused on what you are doing in the short run, in the long run, it dehydrates the body. Dehydration can also lead to the formation of kidney stones. Hence reduce your caffeine intake and instead drink more water and fresh juices.
Quit smoking: Smoking not only affects the lungs but also damages blood vessels thus decreasing blood flow to the kidneys thus preventing the optimal functioning of the kidneys. Smoking can also increase one s risk of suffering from renal cancer.
Get regular exercise: Exercise benefits all parts of your body including the kidneys. Regular exercise reduces blood pressure and helps keep the blood moving. This can help prevent kidney diseases and a number of other conditions. Ideally, aim for half an hours exercise a day at the least.
Eat plenty of fresh fruits and vegetables: Fruits like grapes, apples and blueberries and vegetables like spinach, beets, garlic and red bell peppers help improve kidney functioning. Women should also include oestrogen boosting foods like chickpeas, fennel, tomatoes, cherries and carrots in their diet to protect themselves against kidney damage and fibrosis. Foods that are low in gluten, sugar and soy also help reduce the risk of kidney inflammation.

Kidney - 5 Things To Keep Them Healthy & Fit!

What is diabetic kidney disease?
Diabetic nephropathy, also known as Diabetic Kidney Disease is a type of complication that occurs in people who are a victim to diabetes. That does not mean every individual with diabetes will have this disease, but if the necessary precautions are not taken, then it can lead to this disease. Diabetic Kidney Disease is characterised by excessive amounts of albumin as well as protein in the urine. In diabetics, certain chemicals in the kidneys shoot up and hamper the function of the glomeruli.

The glomeruli are the main units of kidneys that are responsible for the filtration. Diabetic kidney diseases result in the leakage of essential products like albumin and protein into the urine. When this happens, the protein levels in the blood reduce. If proper precautions are not taken and treatment is not done, then the disease may worsen and the condition will progress to  end-stage renal failure .

How to avoid diabetic kidney disease?
The best way to treat diabetic kidney disease is to prevent it in the first place. Foremost, you should prevent the risk factors in order to avoid coming down with Diabetic Nephropathy. The risk factors include high blood pressure, high levels of blood sugar, dyslipidemia and smoking. Avoid excess of following 5S Sugar, Salt, smoke, stress and sedentary life.

Intensive control over blood sugar
According to certain clinical trials, maintaining and keeping a good control over your blood sugar levels drastically reduces the risk of developing diabetic kidney disease. If you are diabetic, make it a point to get your regular checkups and maintain your diet to prevent the levels of sugar in your blood to shoot up. Other things that you must keep in your mind are to take proper medication that has been prescribed to you. You must adhere to your treatment plans and follow the guidelines that have been given to you.

Intensive control over blood pressure
Hypertension is common in patients who are diabetic. Hypertension alone can result in end-organ damage due to excess pressure build up in the blood vessels. Hypertension associated with hyperglycaemia (diabetes) is a ticking bomb for your kidneys. Hence it is advised to keep your blood pressure under control as well to prevent diabetic kidney disease.

Diabetic nephropathy is not something that happens to every individual with diabetes, so if you follow the above simple tips, the chances of the same reduce, and thus the quality of your life goes up. Many diabetics will get kidney failure due to causes other than diabetes and that may be treatable. Hence early consult with nephrologist is a must.

Diabetic Kidney Disease - How It Can Be Prevented?

The ideal diet after a kidney transplant

A kidney transplant is a surgical procedure where your kidneys are cleansed and rebuild using the kidneys of a deceased person, in order to flush out the excessive waste fluids from the kidneys. It is of paramount importance and your dietary patterns and lifestyle should be altered after you go through a kidney transplant. Your dietician will help you out by preparing your diet chart to clearly list out the foods that you should consume and those which you should avoid after the surgery. The diet chart that would be prepared for you would be highly subjective and it would totally depend  on your lifestyle, medical history, family health records, genetically transmitted conditions and such others. Apart from improving the condition of your kidney and assisting your transplant, the diet chart will also help you to lose weight, boost your metabolism and enhance your immune system. Some of the most common recommendations that your dietician may give you are as follows:

-Eating at least 5 full servings of fresh fruits and vegetables each day as both are an important part of a healthy diet for a person who has just undergone a kidney transplant. The vegetables should mostly be eaten after cooking/boiling as per the suggestions of your dietician.
-Having enough of fiber rich foods in your daily diet is essential as it speeds up the process of digestion and prevents constipation by promoting frequent and easy bowel movements.
-If you are a non-vegetarian, then you should be going for lean meat alternatives which are low on fat and high on nutritional value. -Examples of such meat are fishes and poultry. Additionally, you should also avoid all kinds of red meat as it is high on fat.
-Consume low-fat milk and dairy products as they help to prevent the fat accumulation inside the body and also maintain an acceptable level of calcium and phosphorus inside your body.
-Maintain a low level of iodized salt in your meals, as it helps to keep your blood pressure under control.
Over the counter health supplements like vitamins and proteins can also be taken, if recommended by your dietician.

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The Ideal Diet after a Kidney Transplant

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