What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

World environment day is celebrated annually on 5th june. This day encourages awareness and action for the protection of our environment. It raises the problems facing our environment such as plastic pollution, air pollution, illegal wildlife trade, sea-level increase, sustainable consumption, and food security, among others. 

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World environment day is a reminder for us to pause and reflect on our actions and their subsequent consequences on the planet. 

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When was the world environment first celebrated?

The day was first observed in 1974 in the city of spokane in the usa.

 

History of world environment day (wed)

1972- the un general assembly established world environment day on the 1st day of the stockholm conference on the human environment. ;

1974- the first" world environment day" was held with the theme" only one earth. 

1987- the idea for rotating the center of these activities by selecting different host countries began. ;

 

Why is world environment day celebrated? ;

For a healthy life, the environment plays an important role. It provides us with air, food, etc. The environment is like our neighborhood, its surrounding conditions affect us and also modify development. It is really necessary to address the environmental issues like deforestation, increasing global warming, pollution, wastage and losses of food, etc. Currently, our earth is experiencing a triple planetary emergency: 


	
	Pollution is poisoning our air, land and water. ;
	
	
	Climate is heating up too quickly
	
	
	Habitat loss
	


The deteriorating environmental conditions worldwide had already raised alarms in academic circles, among scholars studying its conditions. However, general masses seemed oblivious to changes that were not directly affecting them.

The world environment day is structured in a manner that allows one country to take up the responsibility of selecting the theme and hosting the key celebrations each year. 

Let's all come together and ensure this unique and beautiful planet remains a comfortable home for humanity. 

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World Environment Day: What Is World Environment Day And Why It Is Celebrated? 

Blood is one of the most crucial elements of human existence. It works as a commute for oxygen and various nutrients in reaching the cells. These functions make blood a vital source for the body to operate. That said, india needs 38, 000 blood donations every day, which adds up to 5 crore units required in a year. However, only 2.5 crore units are available against the huge unfulfilled numbers. Hence, it is essential to recognize the importance of blood donation.

 

Why is blood donation important?

While blood donations are essential to help people with surgeries, they are equally vital during cancer treatments, chronic diseases, and gruesome injuries. Moreover, they also benefit the donors in a significant way.

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Types of blood donations

Blood donations are of several types through which a single donor has the potential to help nearly three people.

 

Whole blood donation

It is the most common process of donating blood. One pint of blood collected supports numerous patients in the process. It is, then, divided into different components that aid the donation.

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Plasma donation

The process of plasma collection is carried out through a method called apheresis. It divides plasma from other blood components. Its blood clotting abilities help trauma patients and people undergoing cancer treatment.

 

Platelet donation

The collection of platelets is also done using apheresis. Once identified in the donor s blood, the rbcs and the donor gets other fluids back. Cancer patients are the chief beneficiaries of platelets as they play a prominent role during cancer treatments.

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Double red cell donation

Red blood cells are also collected through the apheresis process. It helps donors to donate twice the dose of a whole blood donation. One can help a patient suffering from blood loss using this method.

 

Advantages of blood donation

Blood donations have several advantages that people should know. They help fight many severe health conditions in the human body. Some of them include-


	
	Loss of blood due to internal or external injuries caused by accidents
	
	
	Sickle cell disease or other abnormalities that affect the blood
	
	
	In the treatment of cancer
	
	
	Cardiovascular or orthopedic surgeries
	
	
	Blood disorders
	
	
	Transplant processes
	
	
	Treatments involving plasma
	


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Covid-19

According to food and drug administration (fda) reports, patients who have recovered from covid-19 can help others by donating blood plasma. They contain antibodies that fight the infection, helping their body fight the virus.

 

Benefits for the donor

Even the donors receive many health and social benefits because of blood donation. Where donated blood saves lives, experts suggest that donors can also benefit from the same. Some of these advantages include:

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	Boosting cardiovascular health
	
	
	Maintaining blood pressure
	
	
	Contributing to the community
	
	
	Reducing the iron levels
	
	
	Improving overall health
	



 

Why Blood Donation Is Important?

International yoga day or international day of yoga is celebrated on 21 june annually. It took a shape in the united nations general assembly in 2014 when indian prime minister narendra modi proposed a day for yoga. The mental, physical, and spiritually enticing practice of yoga started being celebrated in 2015.

 

Yoga and its importance

The term'yoga' is derived from sanskrit which means to reunite or join. It is symbolic of the union of mind and body. Yoga originated some 5000 years ago in india. It was developed as a process to interconnect the mind, soul, and body. As it started gaining popularity in the west, it became an exercise and a method to relax. Through yoga, you can easily calm down your nerves, alleviate any physical concerns, get relieved of any chronic pain, and attain bodily well-being.

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Significance of 21 june

June 21 is also called the summer solstice. It is considered the longest day of the year when the sun is out for most parts of the day. From yoga's perspective, the summer solstice allows the transition to dakshinayana. Hence, it was chosen as an ideal day to celebrate a healthy mind and body.

 

Un declaration

After the draft resolution was presented in the un general assembly, it received support from 177 member countries. Pm modi in his statement emphasized yoga's invaluable importance. He also stressed the fact that how yoga connects us to nature.

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Benefits of yoga


	
	Yoga and fitness
	


Yoga ensures that a person is healthy in its true sense. The different postures of yoga encourage overall fitness and balance of the body. In addition, an enhanced mental strength, physical power, stamina, and detoxification of the body.


	
	Yoga and stress relief
	


Some precious moments of yoga each day is a good way to eliminate everyday stress. Be it physical or mental, certain practices like meditation and pranayama are perfect for preventing stress.


	
	Yoga and inner peace
	


There is a serious need for peace in this robust world. Yoga done regularly gives you extensive inner peace. It is vital to calm your disturbed peace. Moreover, breathing exercises in yoga are very helpful against unwanted stress. Immune system enhancement and protection from frequent diseases is another one of yoga s benefits.



 

International Yoga Day: All You Need To Know!

Environmental factors play a quintessential role in affecting our health. Fresh air, fresh food and fresh water, not only strengthen our body and mind but also make our life worth living. Contrary to this bad environment hampers the quality of life. This is the main reason why people from hill stations or the countryside seem to be healthier than those living in polluted urban cities. Following are the environmental factors that affect your health:

Polluted air

The health effects of polluted air are several. Not many people know that one-third of the deaths are caused because of strokes, lung cancer and heart failure. Air pollution is the chief reason behind these chronic ailments. The other life-threatening diseases caused by polluted air is- asthma or bronchitis. Smoke from machines, vehicles outside, and stoves, the burning of fuels inside can cause breathing problems and wheezing. 

Dirty environment

A dirty environment often leads to the breeding of insects and bacteria that become carriers of life-threatening diseases such as dengue, typhoid, diphtheria, malaria, and so on. Most of the diseases mentioned here are caused by mosquitoes that thrive on stagnant water.

Toxic food ;

The environmental quality of a region has a direct impact on the food produced in that area. Both vegetarian and non-vegetarian food faces the danger of becoming toxic if the environment it is being grown in is polluted. For eg- chemical wastes that are often dumped in water bodies cause the seafood in that area to become highly toxic.

Chemical pollutants

Cancer nowadays is becoming a household disease. The major reason behind this is that technological development has brought new categories of pollutants. Many of these contain chemicals and compounds that are carcinogenic in nature. This ultimately leads to the development of cancer in most people. 

Climate change and natural calamities

Change in climate disrupts the functioning of nature in many ways that further impact the health of humans. These changes include- the natural temperature of the planet, heavy rainfalls and sandstorms. The numerous impacts of climate may result in a high risk of nervous and respiratory diseases. ;

Hence protecting the environment is extremely important for the life of a human being. The change will come after taking small steps. Numerous small steps can really make a difference. 

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Environmental Factors That Affect Health

Headaches are extremely common   we all are familiar with mild or persistent throbbing ;pain. A number of conditions can result in headaches. Some of these include  


	
	Fatigue
	
	
	Lack of sleep
	
	
	Stress/tension
	
	
	An underlying condition, like migraine ;or sinusitis
	


Recent studies have revealed a lesser-known cause for headaches   ;hypertension, or what is commonly referred to as high blood pressure.

The connection between hypertension and headaches

Hypertension occurs when the force of the blood circulation in the arteries is elevated   this particular condition can lead to steady pain throughout the head, particularly at the back of the head or in forehead.

Hypertension-induced headaches usually affect both sides of the head, particularly the temple regions. However, a person may not even realize that the headaches he/she is experiencing are induced by high blood pressure.

Since hypertension is an asymptotic condition, it is often referred to as  the silent killer . When blood pressure rises above 180/110, the condition is known as  hypertensive emergency .

Different types of hypertension leading to headaches

There are three types of hypertension conditions that are followed by mild to severe headaches:


	
	Malignant hypertension- this refers to a sudden, rapid increase in blood pressure that calls for medical attention. This is more common among young adults and women with pregnancy-induced hypertension.
	
	
	Idiopathic ;intracranial hypertension- it is characterized by elevated blood pressure around the brain. Symptoms include vision problems, nausea, ;shoulder pain, thumping noise in the ears, and severe headaches.
	
	
	Hypertensive encephalopathy- this is an extreme condition of high blood pressure, which leads to swelling in the brain. A person with this condition experiences severe headache that becomes worse.
	


Uncontrolled hypertension can be dangerous   headaches induced by such a condition could also become frequent or worsen over time. However, with proper medications and certain lifestyle changes, high blood pressure can be kept under the normal measure. Once your blood pressure normalizes, the headaches will disappear in no time.

How Are Hypertension And Headaches Related?

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