Epilepsy is a disorder in the central nervous system characterized by recurrent seizures. An unexpected rush of electrical activity inside the brain leads to a seizure. Brain activity becomes abnormal and leads to periods of unusual behaviour with loss of awareness at times.

Seizures do not always include unusual muscle movements or convulsions. Untreated seizures can seriously affect the lives of children having them. Epilepsy affects both men and women regardless of their ethnic background and age.

Signs of Epilepsy:

A staring spell
Momentary bewilderment
Loss of consciousness
Jerking movements of arms and legs.
Panic or anxiety
Kinds of Seizures:
Seizures are normally classified as focal or generalized depending on the commencement of abnormal brain activity.

Focal (partial) seizures result from abnormal activity in a particular area of the person's brain. Simple partial seizures may change emotions or the way things smell, appear, feel, sound or taste. It is characterized by tingling and dizziness.
Complex partial seizures or focal seizures with impaired awareness entail a modification of or loss of awareness and consciousness. Repetitive movements are performed during such seizures such as hand rubbing, walking in circles or swallowing.
Thorough testing is needed to differentiate epilepsy from other neurological disorders such as narcolepsy, migraine or mental illness.

Generalized seizures normally affect all areas of the brain and consist of:

Tonic seizures lead to muscle stiffness and normally affects muscles in the person's back, legs and arms.
Atonic seizures or drop seizures lead to a loss of muscle control which makes a person abruptly collapse or fall down.
Myoclonic seizures are visible as short jerks or twitches of a person's arms and legs.
Clonic seizures are characterized by repetitive or rhythmic jerking muscle movements.
Tonic-clonic seizures cause sudden loss of consciousness, quivering and body stiffening.
Absence seizures might take place in clusters and lead to momentary loss of awareness.
Symptoms of Epilepsy:
The main symptoms of epilepsy are seizures and it differs from one person to another.

Symptoms of Focal (partial) seizures include:

Dizziness
Change or modification in the sense of smell, taste, hearing, sight or touch.
Twitching and tingling of limbs.
Symptoms of Complex partial seizures include:

Unresponsiveness
Staring blankly
Performing repetitive movements
Loss of awareness or consciousness
Genetics may provide a person with a natural seizure threshold as a person who is susceptible to seizure triggers is said to have inherited a low seizure threshold. A higher threshold conversely makes a person less liable to have seizures.

Epilepsy is a comparatively common neurological disorder that affects innumerable people worldwide and treatments range from medication to surgery.

Epilepsy - Signs and Symptoms You Must Know!

Surgery to remove abnormal growths of the brain, peripheral nervous system or the spine or any disorder can be tricky because the brain and the skull that shields it are complex areas. In the old days, open surgery was the only way to access the brain or spinal cord. But, with the invention of laparoscopy, keyhole surgery to treat neurological issues is gaining ground.

What is Neuroendoscopy? 
Neuroendoscopy is a surgical procedure that is favoured by doctors and patients alike because it is minimally invasive.
Before the surgery, you will be administered general anaesthesia so that you will be unconscious during the entire duration. During the surgery, the surgeon will drill a minute hole into your skull just above the eyebrows. You skull also has two natural openings. That is why the surgeon may make use of the nose or the mouth to access the region that needs to be operated upon.

Neuroendoscopy is useful because -

  It lets the surgeon reach regions that are not accessible with open surgery
  The tumour can be removed without any damage being done to surrounding tissues

An endoscope is a delicate device with a high-resolution camera mounted on it. There is an eyepiece on the other end. The device is also fitted with a light. When it is inserted into the brain, it lights up the passage and the eyepiece allows the surgeon to take a look inside. The camera sends a live feed of the path it is traversing and this guides the surgeon. When the tumour is reached, it is gently removed with other surgical instruments that too were inserted through the cavities or the drilled hole.

Benefits of Neuroscopy -
There are several advantages of relying on laparoscopy -

  The patient endures less pain
  Fewer chances of infection
  Faster recovery
  Very little scarring of tissues

Which Disorders call for Neuroendoscopy?
Any of the following disorders can be put to rights with a neuroendoscopic surgery -

  Pituitary tumours
  Rathke s cleft cysts
  Pineal area tumours
  Ventricular tumours
  Skull base tumours
  Brain inflammation triggered by an infection
  Chordomas
  Cerebrospinal fluid fistulas
  Trigeminal neuralgia
  Cerebral aneurysm

After Surgery-
Once you undergo the neuroendoscopic surgery, you will have to be rehabilitated so that your condition can be monitored round the clock. Neuroendoscopy is a state of the art clean and efficient surgery that is beneficial to both surgeons as well as the patients.

Know More About Neuroendoscopy And Its Uses!

Epilepsy is a neurological condition that leads to recurrent seizures. Seizures arise when electrical activity in the brain suddenly surges causing a temporary disturbance within the messaging systems located between the brain cells.

Epilepsy is more common in children below the age of two years and adults above the age of 65 years.

Seizure Types

Seizures are classified into two main categories depending on their area of impact. 

A focal seizure is one that affects only one part or area of the brain whereas a generalised seizure affects the whole brain. Further, both focal and generalised seizures have various sub-categories which are as follows-

Previous nomenclature- 

Partial Seizure

  Simple Partial Seizure
  Complex Partial Seizure
  Partial Seizure with Secondary Generalization

Generalized Seizure

  Absence Seizures
  Myoclonic Seizure
  Atonic Seizure
  Tonic Seizure
  Tonic-clonic Seizure
  Mixed Seizure
  Status Epilepticus

Latest nomenclature of seizure types:

Focal seizures-

  Focal aware seizures
  Focal impaired awareness seizures (previously called complex partial seizures)
. Bilateral tonic clonic seizures

Generalised onset seizures-

  Tonic clonic seizures.
  Atonic seizures (sometimes called drop attacks) and tonic seizure.
  Myoclonic seizures.
  Absence seizures.

Symptoms

The well know symptom of epilepsy is a convulsion/ fit, a few other symptoms include-

  Intermittent spells of fainting. When this happens the patient is likely to lose control of his/her bladder or bowel movements. Following this, the person is likely to suffer from extreme tiredness.
  Spells of a blackout with difficulty in remembering
  Becoming unresponsive to any instructions or questions asked during brief periods of time
  Bouts of continuous blinking without any known reason
  Inappropriate movements that keep on occurring
  Changes in sensory perceptions
  Sudden stiffness in the body

Reasons for Epilepsy

Messaging systems within the brain are responsible for every function that goes about in your body. A disruption to this system caused by defective electrical activity leads to epilepsy in a person. Many people inherit epilepsy while others may develop this condition as a result of-

  Head trauma sustained during an accident
  A stroke or a tumour that has affected the brain impairing its normal capabilities
  An injury to the brain before or during birth
  Associated with developmental issues
  Infections of the brain

Treatment for Epilepsy

Epilepsy in childhood can be treated by using medications and by adopting dietary changes in some cases. Medications for epilepsy mainly include-

  Anticonvulsants - Helps control seizures and manages the symptoms of epilepsy
  Medications for nerve pain - Reduce pain that is caused by the damaged nerves

These medications should be consumed as and when prescribed by the doctor. You must consult a paediatrician for this, as he/she will take your child s physical and mental in consideration before starting the treatment.

Seizures that occur in childhood may be benign. This means that it will not continue into one s adult life. Further, those children who have suffered from epilepsy in their childhood have been seen to have normal mental and intellectual development in their adulthood. However, some epilepsy syndromes in children can have a devastating effect on the child.

Seizure threshold is a term that is used to refer to the conditions that are important for the production of seizures. The threshold is lower for people who are more prone to having seizures whereas the threshold is higher for those who do not have a tendency to suffer from seizures.

A Complete Guide To Childhood Epilepsy!

Do you know that Huntington s disease is an inherited disease? This condition leads to the progressive degeneration of the nerve cells present in your brain. Huntington's disease has severe impact on several functional abilities of an affected person and results in psychiatric, thinking and movement disorders.

Causes
Huntington s disease occurs from an inherited defect present in a single gene. It is a form of autosomal dominant disorder, which indicates that a person requires just one copy of the defective gene for developing the disorder. Except the genes on the chromosomes, two copies of every gene are inherited by a person. The affected parent may pass along the defective gene copy or the healthy copy.

Symptoms
Commonly, the symptoms of Huntington s disease start appearing during midlife. It may also affect a person during childhood. The symptoms of this disease vary from person to person. Abnormal movement and weight loss are common symptoms, which occur in all stages.

Early stage

The usual early stage symptoms include the following:

Slight coordination changes, which affect balance and make you clumsy
Uncontrollable fidgety movement
Stiffness and slowing
Irritability and depression
Problems with thinking in difficult situations
Middle stage
With passing time, the symptoms start interfering more with the patient s daily life and activities. You may start dropping things, face trouble with swallowing, and talking. Staying organized may get tough. Certain emotional changes are indicated.

Later stage
In the later stage of Huntington s disease, a patient becomes dependent on others for taking care of them. A patient cannot walk or speak, and fidgety movements are likely to become more severe or may subside.

Treatment
Huntington s disease has no fixed cure. Several measures are followed for managing the symptoms. They are as follows:

Medications are used to manage fidgety movements. Other medicines are also used for controlling any other side effect experienced.
Speech or language therapy may be beneficial in case of speech and swallowing problems.
Physical therapy may help you in improving your control movements. Assistive devices like handrails can be used for managing your changing physical abilities.
Nutritional support is used in which special utensils are used to focus on a nutrient-rich diet.
Exercise is also important for patients with Huntington s disease as it enables them to stay active and fit.
In case you experience any symptom of Huntington s disease, it is important for you to consult a doctor immediately. This is a severe disease and early diagnosis and treatment will prevent the condition from worsening.

Huntington's Disease - Understanding the Stages of Symptoms!

One of the most debilitating conditions that anyone can experience is migraine. They can severely limit you by affecting your personal and professional life as you are in constant pain. Migraine can manifest in a type of headache with intense pain, an acute sensitivity to light, vomiting and nausea. Often described as a severe throbbing pain in the head, it may stop you from completing regular daily tasks and may delay or postpone your work.

How can migraines be treated?
The exact cause for these debilitating migraine pain hasn't been pointed out yet, but certain triggers such as stress, hormonal changes in the menstrual cycle, sun exposure, bright or flashing lights, among many others have been identified. The first line of defense for you would be to understand and identify what your triggers are. Once that is done, you can try and avoid them. If these still trigger a migraine or are about to trigger one, you can immediately take medications or steps to control it or at least lessen the pain to go through your day. Some of the options you can employ to this effect are mentioned below.

Medications to prevent a migraine attack: The medications mentioned here are specialized treatments and can only be taken after a consultation with a doctor. If you are deemed as a candidate for preventative medication for migraines, then either one or a combination of drugs from the following may be prescribed to you.
Valproate and Topiramate are anti-seizure medications which can be used to prevent migraines.
Propranolol, a type of beta blocker and used for cardio vascular problems, has proven to be very effective in preventing migraines.
Onabotulinumtoxin A or a type of Botox, has shown a lot of promise in preventing migraines and is being slowly rolled out as a proper drug as a treatment option.
Certain antidepressants have also shown to be quite effective in reducing the symptoms of migraines as well.
Medications to relieve pain: Some of the go to medications that help relieve your pain from migraine are mentioned below. Although some of them are OTC (over the counter) drugs, it is best advised that you consult with your doctor for medications which suit you better. The side effects of these medications can be bad and thus, it is not advised to continue them in the long run and to find other means to control pain from migraines. Some of the medications to relieve pain temporarily are:
Triptan is a drug used to treat severe migraines
Caffeine along with Ergotamine can also help dull the pain and deal with it.
Ibuprofen and aspirin and Acetaminophen are common pain killers that you can use
Codeine, which contains opioids are also used to treat this problem.
Metoclopramide and chlorpromazine are two examples of anti-nausea medications as vomiting along with nausea may frequently accompany your migraine.
Always remember that these medications can have strong side effects if not taken properly, therefore do not just pop a pill, consult your physician first and know which one should you take and how frequently. 

Severe Headache - Can it Be Migraine?

Parkinson's disease is a neurodegenerative condition that affects your brain cells which produce dopamine and thus hampering all kinds of motor functioning and other emotional responses. After the disease is diagnosed, medication and therapy can help to provide relief from the symptoms to a large extent but a permanent cure is not possible.

Causes:

The disorder does not have a definite set of causes. A small percentage of the cases have been related to hereditary factors and others have a range of environmental causes associated with them.

1. Genetic factors:

Specific gene mutations and gene variations have been proved to cause Parkinson's, such as SNCA, PARK2, PARK7, PINK1 and LRRK2. These make or recycle proteins which are linked to the disease.

Research shows that men are at a 1.75 times greater risk of developing the condition than women are. Also, age plays a role with most cases occurring after the age of 60.

2. Environmental factors:

Regular exposure to inorganic insecticides, pesticides, herbicides and heavy metals or other toxins may cause the disorder. In rare cases, Parkinson's disease occurs in the aftermath of a severe head injury or immune disorders.

Symptoms:

The symptoms can be classified into two broad categories-

1. Motor symptoms:

The hand tremors when in resting position
The grip loosens
Walking slows down
Facial muscles freeze partially
Speech is slurred
Balance is disturbed
Swallowing is painful
Urination is abnormally frequent
Dementia-like symptoms are seen
There is involuntary twitching of the fingers and toes
Repetition of the same movement in quick succession is nearly impossible
2. Non-motor symptoms:

Dental problems
Vision impairment
Skin disorders
Panic attacks
Excessive secretion of saliva
Extreme weight loss or gain
Sexual problems
Loss of sense of smell
Lowering of the pitch of the voice
Fatigue

Causes and Symptoms of Parkinson's Disease

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