Post-Transplant Lymphoprolipherative Disorder (PTLD) is a condition or a reaction that happens post your liver transplantation or any kind of organ transplantation. There is a rapid increase in the immune cells or more precisely, the lymphoid cells in the body. These cells start increasing without any control. The seriousness of this growth can be harmless but sometimes, it can develop into lymph node cancer as well.

The major reason behind PTLD is the anti-rejection medicines that are taken by the patient to avoid rejection and attack by the immune system.

Types of Post-Transplant Lymphoprolipherative Disorder (PTLD)

Early lesions: This will go away by itself, if the dose of anti-rejection medicine is reduced.
Polymorphic PTLD: This is a mixture of different kinds of lymphoid cells.
Monomorphic PTLD: This is the most common type of PTLD found in many people who have undergone a liver transplantation. This has just one type of lymphoid cell.
Hodgkin Lymphoma: This is a very rare kind of PTLD.
Diagnosis of Post-Transplant Lymphoprolipherative Disorder (PTLD)

Small and painless lump under the armpit, groin, or neck area
Night sweats
High fever
Excessive weight loss
Low appetite
Unwell feeling
Usually, it is not at all easy to diagnose PTLD. The lump may grow so deep inside the body that it can be hard to see or feel it from outside. Apart from the lump, others are general symptoms and they can be a reason for any kind of infection in the body post transplantation. It can be a reaction to any new medicine taken by you or a reaction to rejection. Early diagnosis can help you in increasing the chances of a successful treatment. A biopsy is also a good way to detect PTLD, where a small piece of the liver is taken and tested under a microscope to detect PTLD.

Management of Post-Transplant Lymphoprolipherative Disorder (PTLD)
Your liver transplant surgeon is going to work closely with the lymphoma doctor in order to provide the best treatment for you. For early lesions or Polymorphic PTLD, reduction of the anti-rejection dose can give you better results. Your immune system will restore back and will destroy all the abnormal cells in the body. But it has to be done slowly so that it does not cause organ rejection again. If reduction of anti-rejection medicine is not possible or if reduction causes any kind of harm, then other treatment methods like antibody medicine such as Rituximab, or chemotherapy regimen or radiotherapy may be used.

Post-Transplant Lymphoproliferative Disorder (PTLD) - How To Diagnose It Correctly?

Urinary tract infections (UTIs), which are infections anywhere along the urinary tract including the bladder and kidneys are on the most common infections in women. These infections can be caused by poor hygiene, impaired immune function, the overuse of antibiotics and the use of spermicides. The most common cause, accounting for about 90 percent of all cases, is the transfer of E. coli bacteria from the intestinal tract to the urinary tract.

Fortunately, there are a few methods of natural treatment and prevention that are drug free and prescription free and more than are effective as well. Go Natural!

Indian Gooseberry (Amla)
Indian Gooseberry is rich in vitamin C which in turn inhibits the growth of bacteria

Take a cup of water.
Add one teaspoon of Indian gooseberry (amla) powder and one teaspoon of turmeric powder.
Boil the solution until half the water evaporates.
Drink the residue three times a day for three to five days.
You can also eat more fruits like lemons, oranges, bananas, guava, kiwi, melon, raspberries, tomatoes, and papaya that contain a good amount of Vitamin C.

Apple Cider Vinegar
Apple cider vinegar is a rich source of enzymes, potassium and other useful minerals that can prevent the bacteria that cause UTIs from multiplying or growing. Those suffering from UTIs can use apple cider vinegar as 

Natural antibiotic to treat the infection.
Add two tablespoons of apple cider vinegar to a glass of water. You can also add lemon juice and sweeten with honey. Mix it well.
Drink this two times a day for a few days
Baking Soda
Baking soda will raise the acid-base balance of acidic urine and give you relief from the pain. Neutralizing the acidity in the urine also will help speed up recovery. Simply add one teaspoon of baking soda to a glass of water and drink it once or twice a day.

Blueberries
Blueberries have bacteria-inhibiting properties that can help in the treatment of UTIs. The antioxidants present in blueberries are good for the immune system, and they prevent growth of bacteria that causes UTIs.

You can add some fresh blueberries to your favorite cereal and have it for breakfast.
You can also make fresh blueberry juice and have it daily, in the morning and at night for quick results.

Natural Home Remedies for Urine Tract Infection (UTIs) - Natural Cure

Nausea can result from a variety of reasons. While the most cases arise from a hangover, it can also be a result of cancer treatment, patients fresh out of surgery and such other instances. A great degree of environmental changes is necessary such as keeping a cool temperature in the room or staying away from nausea triggering smell. Food also plays great strokes in curbing nausea. Here is a list of 10 best foods that helps to fight nausea:

Apple: Fruits with high fiber content goes a long way in eradicating chemicals that are responsible for causing nausea. Apple is definitely one of them. Consumption of a whole apple can ensure that nausea can t set in.
Crackers: Crackers such as toast, saltines and bread helps the stomach to settle down and effectively absorbs the acid from the stomach. Keeping a few crackers close to the bed or office bag can come real handy in fighting nausea.
Lemon: Lemons are a great agent that effectively blocks nausea and fight morning sickness. This can be consumed along with food, drink in the form of juice or simply sucking on it. Not to mention they are a great source of vitamin C.
Ginger: Ginger is a jack of all trade and master of many. Apart from its enormous nutritional value, it helps a person to fight nausea. This is recommended by Doctors for a patient undergoing chemotherapy or radiation. They can be consumed along with tea, in food or as a whole.
Water: Although water may not be a preferred choice for many during nausea, but it is one of the best agents to fight nausea. It not only keeps the body hydrated but negates acid formation in the stomach. Small sips of water after every half an hour can pay rich dividends in fighting nausea.
Nuts: At times the body suffers from nausea due to lack of protein and nuts contain plenty of them. Even peanut better will serve the same purpose. They ensure that the body is at the threshold of the energy level and keep nausea at bay.
Chicken broth: The Chicken broth is known to help individuals who have a tendency of suffering from nausea. Since broth is prepared of bouillon cubes, they greatly help in absorbing acid from the stomach.
Banana: Bananas are a great source of potassium which becomes essential in cases when a patient is suffering from diseases such as diarrhea. Due to their heavy sugar content banana effectively fights nausea.
Mint: Mint is refreshing for people at any state of mint. Simply chewing a mint leave or preparing a glass of juice from mint can effectively fight nausea.
Chilled food: Contrary to the popular belief chilled foods can effectively counter nausea. They have the double benefit of keeping the stomach temperature under control and easy digestion.

Nausea - 10 Foods That Help You Treat It!

When is your pain chronic?

Your pain is chronic if it last for more than a period of six months. Chronic pain is a long-term pain whose nature can vary from mild to excruciating, and it may trouble you either continuously or at short and regular intervals. Chronic pain is so dangerous that it does not only cause discomfort and inconvenience but also robs you entirely of your capacity to work for a long time.

Chronic pain can occur in a number of organs of the human body like head, joints, back, shoulders, neck etc. In fact, pain in any part of your body can turn into chronic pain. Here are a few symptoms that can help you identify if what you are going through is, in fact, chronic pain:

- persistent and severe body pain

- burning sensation accompanied by the body pain

- fatigue and sleeplessness

- weak immune system

- stiff and sore joints

The 4 types of chronic pain disorders that you should be aware of are:

1. Nociceptive pain

The pain that affects the soft tissues of the body such as the skin and the muscles or the organs that have sensory nerves present in them is called nociceptive pain. The sensory nerves, known as nociceptors can detect the stimuli of pain and send information to the brain and the spinal cord for interpretation. The pain could be either somatic (originating in the outer body) or visceral (originating in the internal organs).

2. Neuropathic pain

This pain is caused when the nerves stop functioning normally. It is caused due to nerve disturbances that result in pain stimuli being spontaneously transmitted to the brain and spinal cord. If you are suffering from this type of chronic pain disorder, you will feel a sharp, shooting and stabbing pain. Neuropathic pain can also be caused due to the formation of neuroma (abnormal growth of the nerve tissue).

3. Psychogenic pain

The pain that is caused by psychological disorders like depression and anxiety is known as psychogenic pain. Sometimes this pain can be accompanied by physical complications like fatigue, body pain and muscle weakness.

4. Idiopathic pain

The pain that exists even though there is no physical or psychological cause for it is known as idiopathic pain. This pain is more common in people who have suffered from a pre-existing painful disorder. Some common examples of idiopathic pain are fibromyalgia (intense pain all over the body) and tmj disorders (pain in the jaw area).

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Related Tip: Why does PAIN occur? Understand the Mechanism of Pain

Your Pain is Chronic if it Falls Under These 4 Types of Chronic Pain Disorders!

The abdomen houses multiple organs and pain in the abdomen could indicate a problem with any of these organs. From a medical point of view, the abdomen and associated pain can be divided into nine areas or quadrants the right, middle and left sideways and the upper, middle, and lower quadrants from top to bottom. The doctor would usually ask the patient to point to the area of the problem for instance, right lower quadrant or upper left quadrant.

With a mental mapping of the organ in each of these quadrants, the diagnosis is arrived at, with confirmation by imaging if required. Some of the most common causes for lower abdominal pain are listed below, and the kidneys are important organs in this area.

Lower left abdominal pain is caused because of the problems in the large intestine, small intestine, spleen, left kidney, ureter, ovaries, fallopian tube, urinary bladder and their associated structures.
Some of the common issues in this area could be menstrual cramps, urinary tract infections (UTIs), left kidney stones, uterine disorders, intestinal obstruction, ectopic pregnancy, constipation, colon cancers, pelvic inflammatory disorder, Crohn s disease, inguinal hernia, and a ruptured spleen.
Lower right abdominal pain can be due to appendicitis, right inguinal hernia, UTI, right kidney stones, colon cancer, menstrual cramps, uterine disorders, intestinal obstruction, ectopic pregnancy, pelvic inflammatory disorders, diverticulitis, Crohn s disease, endometriosis, and lymph node inflammation.
As is evident from this list, many of these are related to the urinary tract and kidneys. Whether it is the kidneys per se, the urinary bladder, the ureters, or the associated nerves and blood vessels, UTIs are very common. And if one of these organs is affected, then the chance of the infection spreading to the surrounding organs is very high. There is a constant flow of urine through these structures, and so the infection can pass through easily.
A person who has had kidney problems would have very characteristic symptoms. The pain would be in the lower back, on either side of the spine, depending on which side is affected. While the pain experienced due to kidney stones is acute and can be stabbing in nature, the UTI would appear in bouts. The associated symptoms should always be kept in mind when identifying and treating kidney problems.
There could be nausea, diarrhoea, blood in the urine, fever, profuse sweating and severe fever, which could help in discovering the problem.
These should not be ignored and diagnosis should be confirmed with blood tests and imaging including X-rays and CT scans. The treatment would depend on the condition, and early identification of the problem leads to better prognosis and a simpler treatment.

Lower Abdomen Pain - Can It Be A Sign Of Kidney Problem?

Throat cancer is as common as breast cancer and more than prostate cancer. In cause of throat cancer, keep smoking as first cause followed by alcohol. 
It occurs when abnormally dividing cancerous cells form growth like tumors in the voice box, vocal cords & other parts of the throat like the tonsils, and the pharynx which is the hollow tube that runs from behind the nose to the top of the windpipe.

The common symptoms of throat cancer include coughing, trouble swallowing, hoarseness, and swollen lymph nodes. There are two primary types of throat cancers according to where they start in the throat- pharyngeal cancer and laryngeal cancer. Pharyngeal cancer forms in the pharynx while laryngeal cancer forms in the larynx or the voice box.

Causes of Throat Cancer
Recognizing potential signs of throat cancer in the early stages of the disease is not easy. Hence, it s critical to know the causes and risk factors for developing this type of cancer in order to be able to diagnose it at a relatively early stage of the disease and prevent a fatality. Common risk factors and causes of throat cancer include:

Gender   Men are up to five times more likely to get throat cancer as compared to women.
Age - Now even young persons in their twenties and thirties are coming with throat cancer.
Exposure to certain chemicals like Asbestos, Nickel, and Sulphuric acid fumes.
The common  lifestyle  causes for throat cancer are smoking or chewing tobacco, as per WHO there is no minimum safe limit of alcohol, vitamin A deficiency due to a diet deficient in green vegetables, and infection with the human papillomavirus (HPV) which causes cervical cancer in women and occurs due to unsafe sex.

Gastroesophageal reflux disease (GERD) and poor dental hygiene are also some of the known causes.

The association of throat cancer with HPV infection, a sexually transmitted virus is very interesting. The Cancer Treatment Centers of America has stated that HPV infection is a risk factor for certain oropharyngeal throat cancers.

Cancer Research UK also warns that oral sex, especially with multiple partners, leads to oral cancers due to HPV infection. It further states that men are also more prone to get infected with HPV through oral sex than women and HPV infection is more common in men who have oral sex with multiple partners.

Apart from this, throat cancer has also been linked to other types of cancers like esophageal, lung or bladder. So, if you ve been diagnosed with any of these, you are at greater risk of contracting throat cancer. These cancers also often have the same risk factors.

You can take a few steps to reduce your risk for throat cancer like stop smoking, reduce alcohol intake, maintain a healthy lifestyle   eat plenty of greens, reduce fat and salt intake, and lose excess weight by exercising regularly. You can also reduce your risk of HPV infection by limiting your sex partners and using condoms. Stop alcohol rather than reduce.

Throat Cancer - What Are The Most Common Causes Of It?

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