Abstract

Background: it is essential to have an understanding of life expectancy and risk factors among patients with sickle cell disease (sickle cell anemia, hemoglobin diseases, and thalassemias). These are required to counsel the patients, target treatment, and plan the right clinical trials.

 

Methods: a research followed 3764 people ranging from birth to 66 years of age and suffering from scd. The procedure was done to understand the life expectancy and calculate the average age at death. Moreover, the study understood the reasons for the death in all 209 adults. It used the proportional-hazards regression analysis to know the risks for an untimely death in adults with sickle cell anemia.

 ;

Results: when the results for young kids and adults with sickle cell anemia were observed, it was found that the average age at death was 48 for women and 42 for men. Moreover, suffering from hemoglobin c disease had an average mortality age of 60 for men and 68 years for women.

 

In people with sickle cell disease, 18% of deaths took place in patients with mainly renal organ failures. 33% of the tested patients were medically free of organ failures but episodes of pain crisis took their life. Out of these patients, 78% experienced chronic pain, chest syndrome, or both, while 22% suffered a stroke that took their lives.

 ;

Clinical modeling showed that people with sickle cell anemia faced acute chest syndrome, seizures, kidney failure, a white-cell count of over 15, 000 per cubic mm, and a low hemoglobin level were related to a risk of early death.

 

Conclusions: results suggested that 50% of patients with sickle cell anemia lived beyond the age of 50. A huge share of those who lost their lives suffered no noticeable chronic organ failure. However, most of them died due to acute episodes of pain or stroke. Early death was seen highest among patients who had symptomatic disease. High levels of fetal hemoglobin suggested improved chances of survival and are assumably a credible source to foresee the risks and other factors related to adult life expectancy.


 ;

Life Expectancy And Risk Factors Involved In Sickle Cell Disease

World sickle cell day is observed annually on the 19th of june to raise awareness of sickle cell-related diseases. It is observed to increase people's knowledge and the understanding required to face the challenges posed by the disease.


 

What is sickle cell disorder (scd)?

Sickle cell disorders or sickle cell diseases are genetic blood disorders that cause an abnormality in the red blood cells. The rbcs turn into sickle-shaped cells that stick together and block the blood flow in the body.


 ;

Types

There are four major classifications of sickle cell diseases-


	
	Hemoglobin ss disease
	
	
	Hemoglobin sc disease
	
	
	Hemoglobin sb+ thalassemia
	
	
	Hemoglobin sb 0 thalassemia
	



 

Symptoms

One can start noticing symptoms of sickle cell in a patient at around 6 years of age. However, they can differ from person to person. Some of the most typical symptoms are-

 ;


	
	Anemia
	


A shortage of red blood cells occurs due to the excessive early dying in 10-20 days. It leads to an oxygen shortage in the body.


	
	Excessive pain
	


Blockage of blood flow due to the change in shape leads to periodic cycles of pain in the body.


	
	Swelling in the body
	


As the blood circulation becomes irregular, swelling becomes a regular phenomenon.


	
	Infections
	


Sickle cell can be damaging to the spleen. It increases the risk of ailments in the body that can be prevented only by antibiotics.


	
	Delayed puberty
	


Oxygen and nutrients carried by the blood are required for growth. As a reason, irregular blood flow can lead to slow growth or delay in puberty.


	
	Vision issues
	


Infected blood vessels carrying blood to the eyes can cause damage to the retina. It can lead to visual problems.


 

Traits and treatment

As sickle cell is genetic, it is suggested to take a test that can detect any trait of the disease. It can prevent any life-threatening risks to the newborn. However, we don't have a complete cure for sickle cell disorders. There are preventive measures that reduce the adversity of the disease to an extent. Procedures like blood transfusions help greatly in minimizing the effects of the disorder.

World Sickle Cell Day: Know All About Sickle Cell Disease

Yoga is the answer for a lot of aspects which everyone desires, such as a peaceful mind, a strong and flexible body and healthy, glowing skin. Yoga is not simply a set of exercises but a lifestyle. Yoga is a complete workout for the body and mind and is a combination of stretching along with deep breathing and meditation. It is a way of keeping yourself fit without doing strenuous workouts and lifting heavyweights. When practising yoga, asanas and nutrition go hand in hand to improve your quality of life. Your digestive system, immunity and energy levels are directly linked to the food you intake. If there is a problem with any of these, yoga asanas can help resolve it.

 

Yoga helps in maintaining overall fitness

 ;

Yoga ensures that you are healthy in the true sense. Health is like a dynamic expression of life based on how happy, loving and enthusiastic you are in life. The various postures of yoga help in maintaining overall fitness, and balance both your mind and body in an ideal way.

 

Yoga boosts immunity

 ;

A combination of asanas and yogic breathing techniques can help boost your immunity. Some asanas to try include viparita karani, bhujangasana, matsyasana and adho mukha svanasana. These poses help lower stress and boost immunity by pumping rich oxygenated blood to all the parts of the body.

 

Yoga always keeps you energetic

 ;

Yoga asanas help increase blood flow and increase the heart's capacity to pump blood through the body. A few yoga poses that can boost energy are the camel pose, tree pose and warrior asana.

 

Yoga relieves stress

 ;

Doing yoga every day is a good way of eliminating the stress that you experience in daily life. It refers to both physical and mental stress. Certain yoga postures, meditation, and pranayama are ideal practices for getting rid of stress.

 

Yoga keeps you calm

 ;

Yoga is very essential for calming your disturbed and troubled mind.

Moreover, yoga poses massage your organs and help in strengthening your muscles. The various breathing exercises and meditation forms associated with yoga are great for releasing unwanted, undesirable stress from your system. 

 ;

Yoga keeps the digestive system strong

 

Yogic asanas such as the spinal twist, apanasana and paschimottanasana can help smoothen the digestive process.

Why Yoga Is Important For Everyone?

Headaches are extremely common   we all are familiar with mild or persistent throbbing ;pain. A number of conditions can result in headaches. Some of these include  


	
	Fatigue
	
	
	Lack of sleep
	
	
	Stress/tension
	
	
	An underlying condition, like migraine ;or sinusitis
	


Recent studies have revealed a lesser-known cause for headaches   ;hypertension, or what is commonly referred to as high blood pressure.

The connection between hypertension and headaches

Hypertension occurs when the force of the blood circulation in the arteries is elevated   this particular condition can lead to steady pain throughout the head, particularly at the back of the head or in forehead.

Hypertension-induced headaches usually affect both sides of the head, particularly the temple regions. However, a person may not even realize that the headaches he/she is experiencing are induced by high blood pressure.

Since hypertension is an asymptotic condition, it is often referred to as  the silent killer . When blood pressure rises above 180/110, the condition is known as  hypertensive emergency .

Different types of hypertension leading to headaches

There are three types of hypertension conditions that are followed by mild to severe headaches:


	
	Malignant hypertension- this refers to a sudden, rapid increase in blood pressure that calls for medical attention. This is more common among young adults and women with pregnancy-induced hypertension.
	
	
	Idiopathic ;intracranial hypertension- it is characterized by elevated blood pressure around the brain. Symptoms include vision problems, nausea, ;shoulder pain, thumping noise in the ears, and severe headaches.
	
	
	Hypertensive encephalopathy- this is an extreme condition of high blood pressure, which leads to swelling in the brain. A person with this condition experiences severe headache that becomes worse.
	


Uncontrolled hypertension can be dangerous   headaches induced by such a condition could also become frequent or worsen over time. However, with proper medications and certain lifestyle changes, high blood pressure can be kept under the normal measure. Once your blood pressure normalizes, the headaches will disappear in no time.

How Are Hypertension And Headaches Related?

To save life and the planet, it is important to follow an eco-friendly lifestyle. This will not only elongate your life span but also helps in sustainable development. Breathing in better air, living in a cleaner atmosphere, eating better food, drinking purer water - all ensure a healthier body. Moreover, the improved aesthetics of a clean environment has positive psychological effects on your brain! protecting your environment is of utmost importance in ensuring your good health. Following are the key health benefits of having an eco-friendly lifestyle,


	
	An eco-friendly human would automatically engage in more physical activity, as they d attempt to choose walking or cycling over driving or using public transports whenever possible. Increased physical activity is directly correlated to one s health and fitness.
	
	
	An eco-friendly lifestyle entails the consumption of more organic food which allows more nutrition and fewer pesticides or chemicals to enter your body. Hence, one becomes less exposed to carcinogenic compounds and other diseases causing or immunity hampering chemicals. Moreover, when one is producing their own vegetables, they end up consuming more seasonal items, which ensures a better diet.
	
	
	City air has multiple pollutants even in the absence of smog that can cause diseases. Fresh or pure air not only contains more oxygen but also lacks harmful pollutants and microparticles that adversely affect one s health. Hence, an environment-friendly lifestyle allows one to improve the quality of the air they breathe and thus, avoid life-threatening diseases. We can do this by replacing our regular vehicles with eco-friendly ones. Also, try carpooling to reduce the emission of pollutants.
	
	
	Cholera, diarrhea, typhoid are just a few waterborne diseases that are transmitted via unclean drinking water. Hence, an improved environment ensures the supply of cleaner water, allowing one to consume its minerals while avoiding its pollutants.
	


Protecting the environment by adopting eco-friendly habits not only improves our own health but also helps us ensure the healthy life for our future generation!

 

Ways To Make Your Lifestyle Eco-friendly

Air pollution affects the overall health of a human being. Whether it comes out of exhaust fumes from cars and factories or smoke from burning stubble air pollution, it is a cause of major concern. The effects of this can be seen in the growing number of asthma and other respiratory diseases. These diseases affect adults and children alike, however, it is the younger generation and elderly people who are more susceptible. Hence, it is extremely important to care about the quality of the air you breathe in. 


 ;

What is the significance of the air quality index (aqi)?

The air quality index is a visual representation of pollutant levels in the air around you. A quick glance at this colour coded map can tell you if the air outside your home is likely to harm you or not. The code is broken down into 6 levels ranging from green which signifies minimal impact to red which marks pollution levels that can harm a healthy person and seriously impact those who are already ill. The higher the aqi, the higher the level of air pollution.

 

What are the steps to reduce air pollution?

Simply talking about how there need to be stricter laws about car emissions and the burning of waste will not help you. Here are a few things you can do to protect yourself and your family from the ill-effects of air pollution.


	
	Carpool: exhausts from cars and other vehicles are one of the biggest causes of air pollution. Do your part to reduce air pollution by restricting the amount you use your car. Try taking public transport to work or carpooling with colleagues. Similarly, avoid making individual trips every time you need something from the market. Make a list and when it s long enough, then step out.
	
	
	Limit indoor pollution: do not smoke indoors. When cooking, keep the exhaust fan on so that the smoke produced does not collect indoors. Avoid spraying air fresheners etc. While they may temporarily make the air smell fresh, in the long run, they contribute to air pollution.
	
	
	Use public transport try to use public transport and avoid the use of personal vehicles.
	


How to protect yourself from air pollution


	
	Refrain from morning walks routines to later hours.
	
	
	Use n95/99 face masks whenever you step out.
	
	
	Use air-purifying plants to purify the air around your surroundings.
	
	
	Ventilate your kitchen, and bathroom to keep yourself away from air pollution.
	
	
	Restrict outdoor activities for kids if there is a high level of air pollution
	
	
	Use air-purifiers in your surroundings.
	
	
	Try to take steam with a few drops of eucalyptus oil every day.
	
	
	Keep your car s environment fresh.
	
	
	Ventilate your home, open your windows and doors and allow the air to circulate during mid hours.
	
	
	Eat jaggery (aka gurr) to flush out pollutants from your lungs.
	
	
	Consume a diet rich in vitamin c, omega fatty acids
	


Hence, the other way to cut down this pollution is by bringing significant lifestyle changes in our daily living. Cutting down the number of diesel and petrol vehicles can also prove helpful. People should shift to cng and electric vehicles for daily commuting. These efforts, if practiced on a regular basis, can bring a huge decrease in pollution.

Air purifiers can also be a healthy option for indoor purposes.

 ;

 

 ;

Why Should You Care About Air Quality?

Don't wait any longer, manage your Anatomist online with a Lybrate doctor today

Consult for Anatomist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES