Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

OCD (Obsessive Compulsive Disorder) is a psychological disorder where you feel compelled to perform irrational tasks in continuous patterns almost ritualistically. These compulsive thoughts may seem, upon examination that they are without any particular reason or rhyme. Naturally, a psychological disorder is not voluntary and people who suffer under this disorder don t voluntarily like to make their lives difficult contrary to some who would say  if you don t like it don t do it. 

It is not a simple matter, OCD can have a lot of underlying reasons which makes life even more difficult and wears you out. You still can t get over a particular thought until you have performed it a given number of times even if it harms your health and the relief is also short lived. For the naysayers who don t realise, how difficult life can be for people suffering from OCD here are a few reasons that you should consider:

Depression: People with OCD are also prone to suffering from depression. A sense of feeling like you are not like others, you see the world a little differently and obsessively repeat such compulsive lines of thought until it wears you out mentally. It is a side effect of OCD and deeply affects their lifestyle negatively.
Anxiety: When you have OCD you suffer from constant anxiety about things you may not have done that you must do or vice versa, or very intrusive thoughts that make you anxious wondering about the kind of person you are or becoming. It is a constant battle everyday trying not to repeatedly perform all the compulsive behaviours that may strike you and makes daily life immensely difficult.
Eating disorders: Suffering from OCD also affects your diet and food habits. You either start over eating or not eating enough resulting in huge amounts of weight gain or noticeable weight loss or just a fluctuation in weight.
Skin rashes: The outer manifestations of OCD are numerous. If you suffer from obsessive, washing of hands or clothes or any activity that requires constantly irritating your skin then you will develop rashes which will cause more anxiety in you. It s just a facet of OCD wherein you become obsessed with cleanliness and can t go without feeling anxious about the number of toxins surrounding you so you go about trying to almost sterilise yourself and end up damaging your skin.
Sleep disturbances: Your sleeping pattern gets affected if you can t build up a routine and then you can t sleep until it s a certain hour at a certain time of the day. Or if you suffer from paranoia then you are unable to sleep because you are actively worried about something or the other. Anxiety also contributes to restlessness.

5 Reasons Why OCD Makes Life Difficult!

Smoking   Some Naked Facts!

Smoking kills > 420,000 people per year worldwide.
In India one million people die of smoking related diseases each year.
Tobacco use is the second leading cause of death world-over.
Smoking is more lethal than AIDS, Accidents, Homicides, Suicides, Fire, etc.
2700 substances have been identified in Cigarette smoke, most of them harmful including cyanide, benzene, formaldehyde, methanol, acetylene, ammonia, nitrogen oxide, carbon monoxide, etc.
Every cigarette takes 5.5 minutes of your life.
Smoking one packet a day for 10 years increases risk for Ischemic Heart Diseases by 300 % & risk for lung cancer by 500 %.
Passive smoking (breathing second hand smoke) is also harmful. Spending 2 hours in a smoky bar is equivalent to smoking 4 cigarettes. Living with a pack-a-day smoker is like smoking 3 cigarettes by yourself.

What are the Risks? 

Cancer: 85% of Lung Cancers and 28% of all cancer deaths are attributed to smoking. Smokers have higher rates of leukemia, kidney, stomach, bladder, and pancreas cancers. About 30% of cervical cancers have been attributed to both active and passive smoking.

Lungs: Smokers are generally at higher risk for nearly all major lung diseases like pneumonia, flu, COPD, bronchitis, emphysema, asthma, etc.

Brain: Smokers run almost two and a half times the risk of stroke as non-smokers and the risk for dementia is also higher in smokers.

Male Sexuality and Reproduction: Smoking decreases the amount of blood flowing into the penis, reduces sperm density, reduces sperm motility, and may lead to impotence & infertility

Female infertility, Pregnancy: Smoking increases the risk of female infertility, ectopic pregnancy, miscarriages, stillbirth, prematurity and low-birth weight, so also there is a risk of passing genetic mutations that increase cancer risks to unborn babies.

Children: Mothers exposed to smoke (active or passive) are more likely to have children with motor control problems, perception impairments, and attention disabilities. Exposure to smoke early on affect the lungs of infant as early as the first 2 to 10 weeks of life, it increases the risk for lower respiratory infections (asthma, bronchitis, and pneumonia) by 50% and worsens the condition of children who have existing asthma.
 
Spine & Bones: Smokers whose jobs involve lifting heavy objects are more likely to develop low back pain than non-smokers. They are at increased risk for developing osteoporosis and rheumatoid arthritis. Smokers are more prone to develop degenerative disorders and injuries in the spine, they have more trouble recovering from spinal surgery as smoking also impairs formation of new bone.

Why Quit?


Physical Benefits: They start as early as in few minutes.

Blood pressure and Pulse rate return to Normal in 20 minutes.
Levels of carbon monoxide and oxygen in the blood return to normal in 8 hours and chance of heart attack decreases in 24 hours.
Nerve endings start to regrow; ability to taste and smell increases within 48 hours.
Bronchial tubes relax; lung capacity increases by 72 hours.
In 2 to 12 weeks  time circulation improves and lung functions improve up to 30%.
In 1 to 9 months  time there is a decreased incidence of coughing, sinus infection, fatigue, and shortness of breath; cilia in lungs start re-growing, increasing the ability to handle mucus, clean the lungs, and reduce chance of infection.
Overall energy level increases.

Smoking - Facts, Risks & Why To Quit!

When man first started using tobacco, he probably did not know that it would grow to be an epidemic that could cause multiple health issues. Be it smoking or chewing, tobacco has severe negative effects on health. Take any of the current lifestyle diseases from diabetes to obesity, the common risk factor is tobacco abuse. In addition, depending on the form of tobacco used, specific organs are affected. For instance, chewing tobacco leads to oral cancer while smoking causes lung cancer.

The statistics around tobacco abuse are extremely startling and can be read below:

A total of about 90 trillion rupees are spent on various tobacco products.
About 1.4 trillion is spent on healthcare-related to conditions caused by tobacco abuse.
India has about 120 million tobacco users.
More than 7 million people die every year due to tobacco usage.
The Government has levied a GST of 28% on cigarettes, making them unaffordable, which is one of the ways to promote quitting.
For those who want to quit but are not able to, there is a quit-line setup, which is toll-free, 1800-11-2356 and is accessible from 8 a.m. to 8 p.m.
Tobacco is a menace in all the strata of society. The lower economic classes are adversely affected both due to lack of knowledge and healthcare facilities. Therefore, the government uses the World No Tobacco Day (WNTD) that is observed by all members of the World Health Organization as an opportunity to drive this awareness.

This is celebrated on May 31st every year. Some measures that are taken to promote 'say no to tobacco' campaign are listed below.

In 1975, the Cigarettes (Regulation of Production, Supply, and Distribution) Act was introduced, which made it mandatory for cigarette packs to have a warning stating  Smoking Kills  or  Smoking is injurious to health. 
Marketing campaigns are shown in the movie theatres at the beginning of movies which depict the hazards of tobacco
Smoking is banned in most public areas, and warnings are on display.
Children below 18 are not sold tobacco products. If in doubt, the seller can ask for age identification.
Schools and colleges do not have tobacco selling within 100 meters of the campus.
The price increase ensures that not everybody has easy access to cigarettes.
Celebrities promote quitting tobacco and smoking by talking about their personal stories.
How can a healthcare professional help you?

A healthcare professional plays a vital role in a smokers life, as it the healthcare professional that can increase the odds of quitting with guidance, medication, and support. 

What should a healthcare professional do?

Identify people who smoke 
Motivate them to quit or think about quitting
Refer a person who smokes for treatment and support
Support ongoing abstinence
What is the right smoking cessation strategy?

Ask: Every smoker to visit a healthcare professional
Advice: Urge the smoker to leave smoking
Assess: Assess whether the person is willing to quit in 30 days
Assist: Plan and help Rx Quit
Arrange: Arrange a follow-up through phone or SMS or in-person
What is that people who smoke need help with?

First and  the foremost challenge are the withdrawal symptoms 
Urge to smoke and borderline depression with a possibility of relapse
People who have high pre-abstinence nicotine intake
How to get over the initial withdrawal discomfort?

Behavioural support is of proven efficacy
Can be delivered in different formats
Face-to-face
Telephone
Internet
Nicotine replacement therapy and nortriptyline are of proven efficacy
Facts On Nicotine Replacement Therapy (NRT)

There are no real contradictions related to NRT
No drug interactions 
Side effects, if there are any are localized e.g.
Taste of oral products
Hiccups with the mouth spray 
Skin irritation with patch 
Treatment for quitting Nicotine  - Medications: Medicines which are useful adjuncts in the determined but unsuccessful quitters are Varenicline and Bupropion. 

Though smoking out in the open has reduced, there are miles to cover when it comes to eradication of tobacco. 

World No Tobacco Day - Making An Effort To Control Tobacco Usage!

Borderline personality disorder (BPD) is a type of personality disorder characterized by an ongoing pattern of varying moods, self-image and behaviour. This often results in impulsive actions and problems in relationships and at work. You may experience intense episodes of various emotions like anger, depression and anxiety that may last for a few hours to a few days.

Diagnosis of BPD
If you experience the following 10 symptoms for a long time or if they have had a huge impact on your daily life, you may say that you are suffering from BPD:

Feeling of being abandoned. You feel that people may abandon you and are constantly worried about that. You would do anything to stop it.
Frequent mood swings. You experience intense emotions that last from a few hours to a few days. E.g. You suddenly start feeling low and depressed after feeling very happy and confident for a while.
Lack of identity. You don t know who you are and do not have a strong sense of your being.
Unable to sustain relationships. You find it very hard to retain relationships and make new ones.
You feel empty from within all the time.
Make impulsive decisions and show sudden reactions. You do things to harm yourself like binge eating, drug abuse or driving dangerously.
You inflict pain on yourself or have suicidal feelings.
You have anger issues which are very difficult to control.
You get paranoid or dissociate when you re stressed.
You experience all your emotions very intensely be it anger, happiness or sadness.
Self-Care - How can you help yourself?
If you start feeling overwhelmed, focus on one feeling at a time. It will help channelize your energy and thoughts into finding a solution for that emotion. Different therapies help different people at different times. You are the best judge to decide what benefits you the most.

Follow these tips to get through the various emotions that you may experience.

When you are angry and frustrated
Rip a newspaper
Hit a pillow
Listen to your favourite music
Go for a walk or do some vigorous exercise
When you are depressed and lonely
Wrap yourself in a blanket and watch your favourite movie or TV show.
Write all the negative feelings on a piece of paper and tear the paper.
Use positive affirmations to comfort yourself.
Cuddle a pillow/pet/soft toy
When you are tensed and anxious 
Try to shift your focus to something else like music, yoga or meditation.
Take a deep breath, use relaxation techniques and focus on your breaths.
Take a warm bath to help soothe your mood.
When you want to harm yourself
Rub ice over the parts where you want to hurt yourself.
Take a cold-water bath to cool yourself.



Borderline Personality Disorder (BPD) - Tips To Help You Diagnose The Problem!

Anger is a type of feeling whereas aggression is a type of behaviour. However, the two are frequently confused with each other. At different times individuals use their anger as a reason to act in an aggressive way. Here are a few differences between anger and aggression:

Anger is an acceptable feeling simply like bliss or sadness. Everybody feels angry once in a while. However, numerous individuals deny that they ever feel angry. For others, they have a tendency to wind up being angry to conceal different sentiments and emotions, for example, hurt and sadness. Angry sentiments can discharge endorphins, which are very powerful chemicals inside the body. This rush of energy can help individuals to alleviate themselves from feeling sad or hurt. Nonetheless, covering these very basic and fundamental feelings with anger is not a sound and healthy coping mechanism. Feeling angry is all right, however, the practice that people show when they feel angry may fall into the category of aggression. Anger is a very normal and typical feeling.

Aggression, on the other hand, is a decision. Just because you feel angry and furious does not give you the authorization to treat others poorly. Forceful practices tend to scare the other individual into doing something whether they need to or not. At the point when individuals carry on forcefully, they do not recognise the other individual's sentiments or necessities. Rather, they want the other individual to give in. There are a bunch of approaches to carry on aggressively and it might turn out to be physically injurious. Verbal types of aggression involve making threats or demands. It might incorporate verbally abusing or putting the other individual down. Physical types of aggression may incorporate tossing things, breaking things, hammering things, or physical assaults.

Aggressive conduct can be separated into different classes. These include instrumental aggression and receptive aggression. Instrumental aggression is objective guided aggression in which harm to another is not the essential objective, despite the fact that it can be an optional consequence of the activity. Another sort of aggression is called responsive aggression. Once in a while, it is referred to as hostile aggression. Responsive aggression is conduct that has harm as its primary and in some cases secondary objective. As a rule, this activity is because of an apparent unfairness, insult, or wrongdoing.

Anger is an impermanent emotional state brought on by disappointment and frustration. Aggression, on the other hand, is a regular attempt to hurt a person or to destroy property. In evaluating the conduct, try to make out the difference between anger and aggression that demonstrates emotional issues so as to lead a more normal and well-adjusted life. One can also take the help of anger management or therapy for better evaluation of the source of anger and its surrounding feelings. 

How to Differentiate Between Anger and Aggression?

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