Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

Urticaria, also known as Hives and Nettle Rash. It is an allergic disorder. It is similar to the rashes that are caused due to touching a nettle plant. This allergic reaction can be caused due to a variety of reasons, thus increasing the difficulty in identifying the exact cause of the allergy. Homeopathic medication has proved to be very efficient in treating urticaria. Some of the best homeopathic remedies include:

1. Apis Mellifica: Described as one of the best solutions to urticaria, this medication is commonly prescribed with regard to treatment. The characterising symptoms of this medication is eruptions accompanied by inflammation and sting. It is similar to the sting of a bee where there is redness and swelling. Exposure to heat in any form is intolerable as the eruption are aggravated. The slightest of touch can cause burning or itching and the patient usually remains thirsty.

2. Dulcamara: This is a medication that is usually prescribed for Urticaria, caused due to cold air or wet weather or dampness. Consumption of sour food or indefinite diet can cause the eruptions. Even though the skin is often dry, there is redness and itching.

3. Natrum Mur: One of the frequently used medicines for urticaria, this medicine is prepared from common salt. It is used in cases where the eruptions are triggered by exposure to the sun, thereby resulting in intense itching. The skin has an oily or greasy feel. Most likely locations of occurrence include margins of hair or bends of joints.

4. Ledum Pal: This medication focuses on the eruptions that occur on the legs and feet. There is a possibility of the infection spreading from the lower to the upper regions at a later stage. Increase in itching can result from the warmth of bed or on scratching. Colder conditions provide a soothing sensation

5. Astacus Fluviatilis: This is an effective medication that be used to treat, both acute and chronic urticarial forms. Rashes are visible on the entire body and are at an increased sensitiveness to air. It is recommended for liver diseases and liver-related symptoms that are accompanied by urticaria.

Best Homeopathic Remedies for Urticaria

Corns and calluses are areas of stumpy skin caused by friction or pressure. They usually hurt when you wear shoes or walk.
Calluses generally develop on your feet or hands, and most of the time, don t require treatment.
Corns have a hard or soft inner core. Soft corns are mostly found between the toes, while hard corns form on the top of the toes. Corns that are caused by ill-fitting shoes often reduce on wearing the right shoes.
Causes-
Repeated friction or pressure causes corns and calluses on areas of skin. The pressure leads to the death of the skin, which develops a protective, hard surface. Soft corns develop in a similar fashion. Corns and calluses are not formed due to viruses and are not harmful. They can be formed due to:
Regular usage of any object that puts strain on the hands, such as sports equipment (badminton racquet) or tools (hammer or gardening hoe), usually leads to calluses on the hands.
Pressure from wearing the wrong footwear usually leads to corns and calluses on the feet. Calluses can also form by walking barefoot.
Abnormal structures on the foot, such as hammertoe or bone spurs, can cause calluses and corns.
Repeated pressure from playing certain sports can also cause calluses on the feet.
Symptoms-
Corns and calluses on the feet are easy to spot. A callus is thick, hard and dry, and may appear yellowish or grey in colour. When touched, it will feel bumpy and more insensitive than the skin around it. A hard corn is thick and firm, while soft corns look like an exposed sore. The hard corn may have a grey centre with a light yellow ring around it.
Corns and calluses don t hurt, but it does become painful when you are wearing shoes or walking. Fitting your feet into shoes gets more difficult due to them. Touching or squeezing the corn or callus can also be painful.
Treatment-
Corns and calluses don t require treatment normally, but if they hurt, here s what you can do:
Wearing well-fitting shoes that are roomy with deep and wide toe boxes (the area covering the toe).
Protective paddings, such as moleskin, toe separator, toe sleeves, etc., can alleviate pain.
Soaking the corn or callus in hot water, and then gently wear down the dead skin by using a pumice stone.
Salicylic acid can be used to soften the corn or callus.


All about Calluses and Corns

Soft growth occurring on the genitals are known as Genital Warts. Genital warts are infections that are transmitted through physical intimacy (STI). These are caused by certain behaviours of the human papillomavirus (HPV). These growths on the skin cause discomfort, pain and itching. They are particularly harmful for women since certain types of HPV might also cause cancer of the vulva and cervix. HPV is one of the most common sexually transmitted diseases. Due to this, sexually active people are most vulnerable to various health complications, including genital warts. Prevention of this infection requires essential protection and treatment.

Symptoms:

Transmission of genital warts occurs through sexual activity. Development of warts occurs several weeks after the infection. Sometimes, it is not possible to view them with the naked eye. The top of the growths might resemble a cauliflower and might feel slightly bumpy or smooth while touching. The person who is infected may have a single wart or a cluster of warts.

In males, the genital warts may appear in the following regions.

Groin
Scrotum
Penis
Thighs
Inside or around the anus
In females, they might occur in:

Cervix
Outside the vagina or anus
Inside the vagina or anus
In a case where the person has had oral sexual contact with the infected person, the genital warts might appear on the mouth, lips, throat or tongue of the person. In case the genital warts are not visible, the other related symptoms include:

Itching
Vaginal Discharge
Bleeding
Burning
Treatment

Even though the genital warts disappear with time, it is not possible to eliminate the virus once it is in the bloodstream. This would result in several outbreaks during the entire course of life. This is a vital reason why the symptoms should be managed so that transmission of the disease is prevented. Treatment is possible only for relieving symptoms that are painful or for minimizing their appearance. Some topical wart treatments prescribed by the doctor may include:

Podofilox and Podophyllin (Condylox)
Trichloroacetic Acid (TCA)
Imiquimod (Aldara)
Some surgeries that the physician might conduct to remove genital warts that do not disappear with time include:

Interferon injections
Laser treatments
Cryosurgery, or freezing warts
Electrocautery, or burning warts with electric currents
Excision, or cutting off warts
Periodic Pap smears after the initial treatment is recommended for women with genital warts to monitor changes in the cervix.

Genital Warts - Can They be Treated? 

Burning your skin is a very traumatic experience and can leave behind scars that remind one of the traumatic incident. Scarring caused by burns may fade a little with time but are usually permanent. Apart from affecting your appearance severe burns can also affect the functioning of the body. Burns can make a person withdraw socially by making him or her afraid of how people will accept them with their scars as well as make them depressed about their appearance.

Burn repair surgery can be categorised under two headings: Acute and Reconstructive

Acute repair surgery happens immediately after the burn and deals with large burns and burns that affect critical areas. The focus here is to close the skin in case of open burns and help the skin heal.
Reconstructive burn surgery addresses the skin after the initial burn wounds have healed. The goal here is to improve the appearance of the scars and ensure no lasting loss of functioning. Reconstructive burn surgery has a high success rate.
There are many types of reconstructive surgeries for burns and the type of surgery best suited to a patient is based on the location of the scar, the extent of scarring and the patient s personal goals.

Skin grafts: This involves the removal of healthy skin tissues from one part of the body and transplanting it to the burn site. This skin graft may include only a few outer layers of skin or may involve the entire dermis. This is used in cases of severe burns where a large section of the dermis is affected.
Microsurgery: This is a procedure where the surgeon reattaches or reconstructs severed fingers, toes, ears etc by sewing together blood vessels and nerves. This is often used alongside other surgical procedures.
Free flap procedure: In this procedure, muscle, bone or skin is transferred from one part of the body to another to reconstruct the area. This type of surgery is often accompanied by microsurgery.
Tissue expansion: This involves the insertion of a balloon expander under the skin near the burn site. As the balloon is filled with saline, the skin stretches and grows. Once the skin has stretched enough, the expander is removed and the skin can then be used to repair burn scars.
This procedure has many advantages as the skin colour and texture are a near perfect match thus reducing scarring to a large extent. However, it is a very slow procedure and can take a few months.

Burn Repair Surgery - How Effective It Is?

Immediately after hair transplantation, you need to exercise little extra care to derive the best benefits. This includes immediate postoperative care, some common with most other surgeries and some very specific to hair transplantation. 

The following things will happen immediately after transplant, throughout the first week: 

Immediately after surgery, like any other surgery requiring anesthesia, there will be slight drowsiness and so it is advisable to arrange for a drive.

Expect some mild swelling and soreness that can be managed with rest and anti-inflammatories.

There will also be a tight and itchy feeling in areas where transplant has been done.

Spray water or saline every half an hour to keep the scalp moist in both the recipient and the donor sites. This promotes healing and also reduces the itchy feeling in these sites.

Thermal shock would be applied to areas to damage the existing follicles and new stem cells would be transplanted. This can also produce a warm feeling, sometimes referred to as 'thermal shock'.

In some people, there could be scab formation which occurs due to fall of the topmost transplanted hair follicles.

If you have undergone a micrograft, then you will have a compression bandage around your head. This should be in place for a day and will cause a tight feeling.

Sleep with your head elevated with a couple of pillows.

The first day after surgery, hair needs to be washed under the supervision of a physician or a nurse. Use a shampoo, which contains tea tree oil.

It is recommended to shampoo your hair regularly from day 2, as it is required to remove the dirt, blood, and oil that often accumulates at the recipient's site. This also helps to controlling infection, which is common post surgery.
Wait for at least 14 days before you resume coloring your hair, use of hair sprays, gels, and other hair care products.

All transplant surgeries require stitches. If the suture material is absorbable, there is no need to follow-up for removal. If it is not of absorbable material, they need to be removed after 2 weeks' time.

Please do not get into a regular exercise routine for up to 6 weeks. Cycling, gymming, swimming, golfing, etc., are to be avoided until the scalp is completely dry and to avoid stretching of the scar.

Everyone's body is unique and responds differently to hair transplantation. Go for periodic review with your doctor to understand how your body is responding.


What To Expect After Your Hair Transplant Session?

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