Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

When you think of organs of the body, the mind goes to internal organs like the stomach, liver etc. However, the largest organ of the body is the skin. Given its size and the amount it interacts with external stimuli, the skin is susceptible to a number of infections. One of the common issues to affect skin is known as psoriasis. This is typically seen as a rash that can make the skin dry, thick and flaky. It can make the skin feel very itchy and make the person unconsciously scratch his or her skin so hard that it bleeds. Although, even modern medicine does not have a way to cure psoriasis but can manage the symptoms. In contrast, homoeopathy can help treat the factors triggering this infection and hence keep it from recurring.

Homeopathy is a holistic form of medication that treats not only the symptoms exhibited but also the issues triggering the infection. Homeopathic medicines are usually prescribed in the form of sweet pills, powders or liquids. This form of medication has negligible side effects and can be prescribed to children and adults of all ages. If needed, it can be prescribed along with other types of medication as well. However, homeopathy does not follow a one size fits all approach. This means that a remedy that suits one person may not be effective for another. This is because the ideal homeopathic prescription depends on the symptoms being exhibited by the patient, his or her overall physical and mental health, family history, personality etc.

There are a number of homeopathic remedies that may be prescribed to treat psoriasis. Some remedies can treat psoriasis that is passed on genetically from one generation to another while others can treat psoriasis caused by exposure to warm or cold conditions. Homeopathy can be used to treat psoriasis that makes the skin dry as well as psoriasis that leads to oozing lesions. It can also be used to treat chronic cases of psoriasis. In many cases, two or more remedies may be prescribed simultaneously.

When taking homeopathic remedies one must follow the prescribed schedule. Medicines must be taken half an hour before or after meals. When taking two or more homeopathic medicines, they must be spaced at least 5 minutes apart. The ideal time to take the morning dose is as soon as one wakes up. Similarly, the best time to take a night dose is just before going to bed.

Psoriasis And Homeopathy - What All Should You Know?

6 effective ways to get rid of warts

Warts are small, rough patches on the skin (resembling cauliflowers) that are caused due to the human papillomavirus (hpv- a dna virus that can infect humans). In this condition, only the topmost layer of your skin gets infected and acquires a rough texture. Warts are not fatal (they do not cause cancer), but they are contagious in nature and do not vanish easily. 

Read on to find the most effective ways to get rid of warts. 

1. Over-the-counter wart removers
Over-the-counter wart treatments containing salicylic acid (a type of fungicide) as an active ingredient are commonly used for effective removal of warts. These medications generally eliminate warts by removing the topmost layer of the skin, following the peel-off process.

2. Cryotherapy
Cryotherapy, also known as freezing therapy, is generally performed by a dermatologist and consists of the use of liquid nitrogen for freezing the warts. The application of the chemical results in the formation of a blister around the warts, which shed off after about a week. It takes almost 3 to 4 weeks to have completely wart-free skin. This method proves to be more effective when used with salicylic acid-based wart removers.

3. Laser treatment
Another form of wart removal is pulsed-dye laser treatment. An ablative co2 laser acts by cutting and burning the wart. In this type of treatment the affected blood vessels are burnt, leading to the death of the infected tissue, following which the wart too disappears. However, this method is not commonly used if other treatment methods tend to work as it is painful and may leave behind scars.

4. Vaccine
Sometimes your dermatologist may recommend the use of human papillomavirus (hpv) vaccine to successfully eliminate warts.

5. Bleomycin
In this type of treatment each wart is injected with a shot of bleomycin, a medicine that fights cancer. However, this treatment is not preferred generally as it may be painful and comes with side effects like nail loss if the wart is present on the finger.

6. Immune therapy
When warts refuse to vanish after the use of all common treatments, this method is put into use. This type of treatment involves the use of medications or solutions, which strengthens your immune system so that it can repel warts. In this case your warts may be injected with an antigen or a solution or cream may be applied on them. 

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6 Effective Ways to Get Rid of Warts - Cauliflower-like Skin Inflammation

 Hives , also known as urticaria, is the outbreak of pale red, swollen bumps on the body. It can occur on any part of the body including the face, back, arms or legs. It is a type of hypersensitivity reaction in which the cause for the reaction is idiopathic (unknown). Also, it can come in various shapes and sizes. Hives can be associated with redness, itching, and a burning and stinging sensation. These can last for more than a minute or even more than that; up to days.

What causes hives?
Most of the times, hives are idiopathic, i.e. the reason that causes this type of hypersensitivity reaction is unknown. The bumps are caused by the action of histamine that makes the plasma in the blood leak out of the small blood vessels. Histamine is a substance that is released from a specialized cell and is what causes allergic responses in general. There are three types of hives- namely, acute, chronic urticaria and physical urticaria. Acute urticaria is when the hives last for less than six weeks. Chronic urticaria occurs when the hives last for more than six weeks. 

Physical urticaria refers to the condition when the hives are triggered due to causes such as heat, cold, sun exposure, sweating, pressure and exercise. Although, this condition is mainly idiopathic, there are common causes that may trigger this condition such as:

Foods such as nuts, fish, chocolates, milk and milk products
Environmental triggers such as pollen grains, dust etc
Medications such as ibuprofen or paracetamol
Insect bites
Latex
Blood transfusion
Bacterial infections including strep throat and urinary tract infection
Pet dander
Plants such as poison oak or poison ivy
What are the symptoms of urticaria?
Hives are usually self-diagnosable. The various symptoms of urticaria are:

Swollen red bumps known as weals
The red bumps can occur suddenly and subside all of a sudden as well
 Blanching which is characterized by the whitening of the swollen red part.
They occur on any part of the body and can change shapes, and sizes. It can become larger or it can reduce in size; it can also move around in the body.

Hives - Most Common 9 Reasons Behind It!

Vitiligo is a disease which results in the loss of skin colouring pigment and ultimately the person loose his or her skin colour in blotches. The rate and to what extent the colour loss will happen is always unpredictable. When the Melanocytes cells lose their ability or get destroyed completely, the human skin starts losing it's skin colour produced by these Melanocyte cells. Vitiligo can generally affect skin present of any body part. Vitiligo is a common disease and it affects almost one million people every year all over the world. The disease can affect a person of any age.

Causes of Vitiligo

There are different causes due to which Vitiligo is caused. Let us have a look :

Vitiligo can happen due to an autoimmune disorder, when the immune system becomes overactive and results in the destruction of the colour pigment-producing cells i.e. the Melanocytes.
Vitiligo is also believed to affect people because of genetic factors. The immune system can get affected by the genes and results in a loss of skin colouring melanocytes. It can be hereditary and gets passed on. However, it is not at all contagious and cannot be passed on to someone else.
Harmful exposure to UV rays can cause the body to loose melanocyte cells. Heavy sunburn is also a common cause of the disease.
A stressful life schedule or oxidative stress imbalance can easily make the melanocyte cells to go weak and eventually wither away.
A foreign virus or bacteria which may enter into the immune system and if not destroyed affects the melanocytes in different parts of the body.
Treatment for Vitiligo-

Vitiligo Treatment or White Patches Treatment is based on improving your skin s appearance by restoring its colour. Re-pigmentation treatment is most successful on face and trunk; hands, feet and areas with white hair respond poorly. Compared to long-standing patches, new ones are more likely to respond to medical therapy.

The treatment can be classified into

Medical

Medicines applied to the skin, such as:
Corticosteroid creams or ointments
Immunomodulator creams or ointments, such as Elidel & Protopic
Topical drugs such as methoxsalen (Oxsoralen)
Oral Medical treatment includes the use of immune-modulating drugs such as systemic corticosteroids, levamisole, cyclophosphamide, azathioprine, vitamin supplements (especially vitamin B12 and folic acid).
Phototherapy NBUVB full body   A medical procedure in which your skin is exposed to ultraviolet A (UVA) or ultraviolet B (UVB) light from a special lamp in full body chambers.
Excimer (Targeted Phototherapy)   Targeted phototherapy, also called concentrated phototherapy, focused phototherapy and microphototherapy, involves delivery of ultraviolet radiation directly focused on, or targeted at, the skin lesion through special delivery mechanisms.
Surgical Procedures

Surgical treatment   Normal skin is used as donor tissue and then grafts are surgically transplanted on areas of Vitiligo treatment. The new skin grafts start producing pigment. Patients who are candidates for this procedure must have stable Vitiligo, or Vitiligo that has not changed for at least one year. The criteria of stability is taken as (a) no new White patches, (b) no extension of existing White patches and (c) no loss of pigmentation of previously repigmened patches for at least 1 year. This procedure can be used for patients with limited areas of Vitiligo and also in those with more extensive disease.
Melanocyte cell transplantation   In this procedure, a skin graft is taken from the patients own thigh, this skin is then treated with an enzyme known as trypsin which separates all the layers of the skin and thus Melanocytes and Keratinocytes are concentrated. The Vitiligo (Skin White Spot) skin is then removed with the use of diamond burs or Lasers and the cells are transplanted. The advantage of this procedure is that cell culture is not needed and that skin harvesting from the donor area, preparation of cell separation and application of Melanocytes can all be undertaken in a single 3-h procedure.
Blister Grafting   In this procedure, blisters are created on your pigmented skin primarily by using suction. The tops of the blisters are then cut out and transplanted to a depigmented skin area where a blister of equal size has been created and removed.
Punch grafting  Punch grafting is the simplest and the least expensive of all the grafting procedures in Vitiligo. The procedure involves the transfer of circular pieces or punches of skin tissue from the donor area into similar shaped pits that are made on the recipient skin. The size of these punches can range from 1 mm to 2 mm and they are spaced 5-10 mm apart on the recipient skin.
De-pigmentation  Depigmentation involves fading the rest of the skin on your body to match the already-white areas. If you have vitiligo on more than 50 percent of your body, depigmentation may be the best treatment option. In this procedure, the drug monobenzone (Benoquin) is applied twice a day to the pigmented areas of your skin until they match the already-depigmented areas. Some patients who are resistant to depigmentation with drug monobenzone (Benoquin) will need Q Switch NDYAG Laser to destroy the pigment cells. Depigmentation in most patients is a permanent technique in which the whole body is gradually turned white.
Color (Camouflage)   Camouflage used to treat vitiligo can be classified into two- temporary and permanent. 
Temporary colouring is the method which intends to blend the white patches with the rest of the body s colour. The method is done using coloured creams to the affected skin. Those creams will have the same shade as that of the natural skin. Applying the creams make the patches less noticeable.
Tattooing (permanent coloring)   Tattooing is injecting artificial pigment into the depigmented area. After selecting the pigment shade which matches the surrounding skin color, the pigment granules are implanted into the depigmented patch either with a manual or electrically driven needles. Though the patch resembles the surrounding normal skin, it may permanently fade or acquire a bluish hue after 1   2 years which is distinctly noticeable and may become unacceptable. Hence, tattooing is usually not advised unless the patch is in an inoperable site.

Best Vitiligo Treatment  - Medical & Surgical Methods

Acne could be a real headache for normal skin. It not only ruins your face, but is also tough to get rid of. The condition is characterized usually by red pimples or blackheads and occurs due to infected or inflamed sebaceous glands. If you are skeptical about using chemical products, here is list of acne related treatments with alternative medicines:

1. Apple cider vinegar: Apple Cider Vinegar has multiple qualities. It can dry up the excess oil present in the face thereby ensuring that the bacteria cannot feed upon it. Its alkaline property helps the skin's pH to come down to an accepted level. Last, but not the least, apple cider vinegar directly attacks the acne causing bacteria and eradicates them from within. This pack is easy to prepare and can be applied multiple times a day.

2. Honey and cinnamon combo: Cinnamon possesses antimicrobial properties and attacks acne right from the word go. Honey, on the other hand, is a natural cleanser which helps to drive out the acne from your face. The pack is prepared by mixing 2 spoons of honey and 1 spoon of cinnamon. Before applying it on the face, it has to be ensured that the face is rinsed well with water. Owing to the pack's sticky nature, it should not be left on the face for more than 15 minutes.

3. Milk and honey paste: There is a wide misconception about milk causing acne. Unless injected inside the skin, milk actually improves the skin tone and limits acne outbreak. It also helps in reducing skin irritation and redness. Honey has antibacterial properties and fights acne. The pack is prepared by adding 1 spoon of honey and 1 spoon of milk and applied on the face for no more than 10 - 15 minutes. The mask can be washed off with warm water and by lightly rubbing the skin in circular motion.

4. White portion of the egg: The white portion of the egg has unaccountable benefits. Being rich in protein, it helps to fight acne and reduces blemishes of the skin. The vitamin present in the white portion combat acne and soak up excess oil present in the skin. This pack should be applied for 15 minutes followed by a thorough face wash with lukewarm water.

5. Mashed papaya: Papaya ingredients are found in almost all beauty products these days. Raw papaya is a great remedy for acne problems though. Papaya also helps to remove excess fat from the skin and eradicates dead skin. It contains an enzyme called Papain, which is known to have anti-inflammatory properties. It also restricts pus formation in the skin. Papaya can be mashed evenly and applied on the face for 15-20 minutes before washing it off with plain water. This pack can be tried three or four times a week to see visible changes in the face.

Acne Treatment With Alternative Medicine

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