Lariago 250 MG Tablet

Lariago 250 MG Tablet is an anti-malarial medication to prevent and treat malaria, a disease caused by parasites in countries where malaria is common. It works by interfering with the growth of parasites in the red blood cells of the human body.

Lariago 250 MG Tablet is also used to treat infections caused by amoebae occurring outside of the intestines, lupus erythematosus and rheumatoid arthritis. It is administered orally. The functioning of the liver and blood cell count should be checked from time to time while taking this medicine.

This medicine is not recommended in patients with the eye or ear disease and who have faced serious allergic reactions to any antimalarials in the past. It is not known if the medicine can cause harm to a baby so it is a safer option to not take this medicine during pregnancy or breastfeeding. Discus with your doctor the risks of taking this medication if you suffer from :

• Psoriasis
• Porphyria
• Liver disorder
• Alcoholism
• Epilepsy
• Other seizure disorder.

Common side effects include muscle problems, diarrhoea, loss of appetite, and skin rashes. Some serious side effects may include problems with vision, low blood cell levels, muscle damage and seizures.

Usual initial dosage for acute malaria and hepatic amoebiasis in adults is 600 mg, then dose is decreased to 300 mg a day. For severe malaria, 25 mg/kg should be given in several infusions over 30-32 hr. Lariago 250 MG Tablet should be taken with food.

Ensure that the course of treatment is completed before discontinuing the doses to prevent the spread of infection. The effect of this medicine can be observed in 1 to 2 hours and lasts for an average duration of 9 to 15 days.

Symptoms of overdose include headache, visual changes, cardiovascular collapse, seizures, abdominal cramps, vomiting, cyanosis, methemoglobinemia, leukopenia, respiratory and cardiac arrest. Following initial measures (immediate GI decontamination), treatment is supportive and symptomatic.

It is important to complete full course of therapy which may take up to 6 months for full effect. May be taken with meals to decrease GI upset and bitter aftertaste. Avoid alcohol. You should have regular ophthalmic exams (every 4-6 months) if using this medication over extended periods.

• Malaria Prophylaxis

• Malaria

• Amebiasis

• Allergy

• Retinal Or Visual Field Changes

• Blurred Vision

• Confusion

• Diarrhoea

• Dizziness

• Skin Rash

• Hair Loss

• Skin Itch

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 9 to 15 days.

• What is the onset of action?

  The effect of this medicine can be observed in 1 to 2 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended in pregnant women unless absolutely necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is known to excreted through breast milk. It is not recommended in for breastfeeding women.

• Is It safe with alcohol?

  It is not known whether this medicine is safe to be consumed with alcohol. Please consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine causes side effects that affect the alertness of the patient. Thus patient must avoid driving if taking this medicine.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

• Does this affect kidney function?

  Caution must be taken in patient with kidney disease. Adjustment of dose might be needed. Clcr <10 mL/minute: Administer 50% of dose. Hemodialysis: Minimally removed by hemodialysis. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Lariago 250 MG Tablet , and hence can be used as its substitute.

• Emquin 250 MG Tablet

  Merck Consumer Health Care Ltd

• Mahaquin 250 MG Tablet

  Mankind Pharmaceuticals Ltd

• Maliago 250 MG Tablet

  Cipla Ltd

• Nivaquine P 250 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Resochin 250 MG Tablet

  Bayer Pharmaceuticals Pvt. Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Contact the doctor in case of an overdose.

This medication is an antimalarial drug that works by inhibiting the enzyme heme polymerase which prevents the conversion of the toxic heme molecules to the nontoxic hemozoin, in parasites that cause malaria. The toxic heme accumulates leading to death of the parasite.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  • Ethambutol : These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.
  • Fluconazole : These medications may increase the risk of irregular heart rhythm. Inform the doctor if you are receiving any heart medications. Close monitoring of heart function is necessary. Discontinue the treatment if you develop any symptoms of palpitations, dizziness, and difficulty in breathing.
  • Tramadol : These medications may increase the risk of seizures if taken together. Inform the doctor if you are having any history of seizures or head injury. Any symptoms of seizures should be reported to the doctor. An alternate class of medication should be considered based on the medical condition.
  • Quinidine : These medications may increase the risk of irregular heart rhythm. Inform the doctor if you are receiving any heart medications. Close monitoring of heart function is necessary. Discontinue the treatment if you develop any symptoms of palpitations, dizziness, and difficulty in breathing.

• Interaction with Food

  Information not available.

• Interaction with Disease

  • Oculotoxicity : This medicine is not recommended in patients with the eye disorder. Close monitoring of eye function is necessary. The treatment should be discontinued if any symptoms of blurred vision, difficulty in reading appear.
  • Other diseases : Use with caution in patients with liver disease, G-6-PD deficiency, alcoholism or in conjunction with hepatotoxic drugs, psoriasis, porphyria may be exacerbated; retinopathy (irreversible) has occurred with long or high-dose therapy; discontinue drug if any abnormality in the visual field or if muscular weakness develops during treatment.

• Ques : What is Lariago 250 MG Tablet?

  Ans : Lariago 250 MG Tablet is an antiparasitic medication which helps to cure malaria.

• Ques : What are the uses of Lariago 250 MG Tablet?

  Ans : This drug is used to treat malaria. It helps by increasing heme levels in the blood.

• Ques : What are the side effects of Lariago 250 MG Tablet?

  Ans : This drug can cause problems like Rash, Headache, Dizziness, Vomiting, Nausea, Stomach pain and Itching in some individuals.

• Ques : Is Lariago 250 MG Tablet available over the counter?

  Ans : Yes, this drug is available over the counter medicine.

• Ques : Is Lariago 250 MG Tablet safe in G6PD deficiency?

  Ans : This drug is not suitable for those who have G6PD deficiency. Consult your doctor before taking it or prefer some other alternative.

• Ques : Is Lariago 250 MG Tablet banned in Nigeria?

  Ans : Yes, it is banned in Nigeria.

• Ques : What is the Lariago tablet/Lariago syrup/Lariago-DS/ Resochin used for?

  Ans : All of them are the trade names by which Lariago 250 MG Tablet is available in the market.

• Ques : Does Lariago 250 MG Tablet affect birth control/ affect the birth control pill/contraceptive pill/ menstrual cycle?

  Ans : This drug does not affect the functioning of birth control or contraceptive pill/ menstrual cycle. In case you observe any such side effect, consult a doctor on an immediate basis.

• Ques : Does Lariago 250 MG Tablet cause nightmares/insomnia?

  Ans : Lariago 250 MG Tablet can cause few side effects, however, nightmares or insomnia is a very rare side effect of this drug. Please consult a doctor if you have this symptom.

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• CHLOROQUINE PHOSPHATE tablet, coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2021 [Cited 24 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cc0cb812-48f9-a138-e053-2a95a90a7666

• Avloclor Tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 3 December 2021]. Available from:

  https://www.medicines.org.uk/emc/product/5490/smpc