What is In- Vitro Fertilization?
In Vitro fertilization (IVF) is a process of fertilization where an egg is combined with sperm outside the body, in vitro ("in glass"). This process involves stimulating a woman's ovulatory process, removing an ovum or ova from the woman's ovaries and fertilizing them with sperms in a liquid in the laboratory. The fertilized egg (zygote) undergoes embryo culture for 2–6 days, and is then transferred to the same or another woman's uterus, to establish a successful pregnancy.The success rate depends on various factors such as maternal age.
Cause of infertility
- Embryo status
- Reproductive history
- Lifestyle factors
Ways to increase the success rate of In-Vitro Fertilization:
- Maternal age: Young age females undergoing IVF are more likely to get pregnant with a donor egg as compared to women older than 41yrs of age. If a woman undergoes IVF treatment by 23–39 years of age, the success rate is higher.
- Reproductive history: Women who have been previously pregnant have higher chances of being successful with IVF treatments than those who have never been pregnant.
- Avoid tobacco smoking: As it reduces the chances of IVF producing a live birth by 34% and increases the risk of an IVF pregnancy miscarrying by 30%.
- Maintain Body mass index (BMI) between 20-27: A body mass index over 27 causes a 33% decrease in likelihood to have a live birth after the first cycle of IVF.
- Avoid obesity: Pregnant women who are obese have higher rates of miscarriage, gestational diabetes, hypertension, thromboembolism and problems during delivery. Obesity in pregnancy may also lead to an increased risk of fetal congenital abnormality.
- Reduce alcohol and caffeine intake: As increased alcohol/caffeine intake decreases success rate of IVF.
- Number of embryos: Increasing the number of embryos transferred in the treatment cycle increases the success rate of conceiving.
- Getting treated for illnesses before IVF: Taking proper treatment for the underlying autoimmune disease before starting with IVF treatment is essential as it plays a role in decreasing IVF success rates by interfering with proper implantation of the embryo after transfer.
- Treating infectious disease: If the female undergoing IVF is suffering from any infectious disease like Rubella, Toxoplasmosis, etc needs to take treatment for the same as it may increase the failure rate of IVF by causing miscarriage/abortion or it may cause failure to hold the fetus.
- Mental state: The mental state of the female while undergoing IVF plays an important role. Females undergoing any kind of stress either physical or mental have higher chances of failure.
- Good clinic: Getting IVF treatment done from a good clinic and experienced doctor helps in achieving success.
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