I want to do anal sex with my wife. Is it safe.

Question

Anal sex can expose its participants to two principal dangers: infections due to the high number of infectious microorganisms not found elsewhere on the body, and physical damage to the anus and rectum due to their fragility. Risk of injury to the woman is significantly higher because of the durability of the vaginal tissues compared to the anal tissues.
Though anal sex alone does not lead to pregnancy, pregnancy can still occur with anal sex or other forms of sexual activity if the penis is near the vagina and its sperm is deposited near the vagina's entrance and travels along the vagina's lubricating fluids.

Niraj Mahajan · Accepted Answer

Anal sex can expose its participants to two principal dangers: infections due to the high number of infectious microorganisms not found elsewhere on the body, and physical damage to the anus and rectum due to their fragility. Risk of injury to the woman is significantly higher because of the durability of the vaginal tissues compared to the anal tissues.
Though anal sex alone does not lead to pregnancy, pregnancy can still occur with anal sex or other forms of sexual activity if the penis is near the vagina and its sperm is deposited near the vagina's entrance and travels along the vagina's lubricating fluids.