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Zinase-D Tablet

Manufacturer: Rapross Pharmaceuticals Pvt Ltd
Medicine composition: Diclofenac, Serratiopeptidase
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: May 21, 2019

Zinase-D Tablet is an anti-inflammatory painkiller. This non-steroidal drug is used to alleviate symptoms of arthritis such as inflammation, pain, fever and swollen joints. It is used in the treatment of conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylosis and severe menstrual pain. This medicine is available in tablet form.

Zinase-D Tablet works by obstructing the production of cyclooxygenase, which synthesizes the compound called prostaglandin. This compound is responsible for symptoms of arthritis such as pain, swelling and inflammation. Therefore, Zinase-D Tablet is effective in providing pain relief.

Zinase-D Tablet is a non-steroidal anti-inflammatory drug (NSAID) that provides relief from pain, inflammation, stiffness, joint pain and swelling. This medicine is used in the treatment of conditions such as muscular pain due to injury, rheumatoid arthritis, painful menstrual cramps, Osteoarthritis, ankylosing splondylitis and migraines. Zinase-D Tablet works by stopping the production of cyclooxygenase, which is responsible for synthesizing a compound called prostaglandin. The synthesis of these compounds in the body is what causes inflammation, swelling, fever and pain. It also inhibits the production of bacterial DNA.

Zinase-D Tablet is available in the form of tablets. The effect of each tablet lasts for 11 to 12 hours. Therefore, the standard recommended dosage is twice a day. It is advisable to take this medication only under the guidance and recommendation of a medical practitioner. You should continue taking this medication until you have completed the course, and discontinue as per the instructions of your doctor. You should not skip out on a dose, and avoid doubling the dosage to make up for having skipped the dose.

In certain cases, it is imperative to inform your doctor before starting a course of this medication. People who are about to undergo a bypass heart surgery or have an allergy to other anti-inflammatory painkillers should not take Zinase-D Tablet. It is important to notify your doctor before beginning a course of this medicine, if you suffer from disorders such as heart disease, heart attack, stroke, hypertension, high cholesterol levels, diabetes, asthma or a bleeding disorder. Pregnant women, women trying to conceive, smokers and alcoholics should avoid taking Zinase-D Tablet, since it can have harmful effects.

The common side effects that this medicine causes include diarrhea, heartburn, dizziness, headache, stomach pain or cramps, black stool, weight loss and fatigue. Not all of these symptoms are a cause for concern. However, if any of these symptoms persist for more than two-three days, you should contact your doctor. An allergic reaction to Zinase-D Tablet would cause itchiness, rashes, vomiting, difficulty breathing, hives and swollen tongue or face. Some of the major side effects of this medicine are an increase in blood pressure, stomach ulcers, gastrointestinal bleeding, nosebleeds, severe skin reactions and liver damage. Taking this medicine in excess can also increase your chances of developing some fatal conditions such as a heart attack, a stroke or hepatitis or kidney dysfunction. If you experience any of these harmful side effects, you should seek medical expertise immediately.


Mild to moderate pain


Peptic ulcer

Coronary Artery Bypass Surgery (CABG)

In addition to its intended effect, Zinase-D Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Abdominal pain

Moderate Less Common


Moderate Less Common


Moderate Less Common

Nausea and vomiting

Moderate Less Common

Skin rash.

Moderate Less Common


Moderate Less Common

How long is the duration of effect?

The effect typically lasts for an average of 1-2 hours. However, the time might vary depending upon the dosage form administered.

What is the onset of action?

The effect can be observed within 10-30 minutes of consumption. Note: Potassium salts of Diclofenac act faster than the Sodium salts as they are absorbed faster from the Gastro-Intestinal Tract.

Are there any pregnancy warnings?

This medicine is not considered safe during pregnancy especially after 30 weeks of gestation. You should consult a doctor before using this medicine. Potential benefits and risks involved should be given due consideration before administration.

Is it habit forming?

No habit forming tendencies were reported.

Are there any breast-feeding warnings?

This medicine is not likely to pass into milk and cause any severe effect. But it is not recommended to use since there is a lack of conclusive evidence. A doctor must be consulted before taking the medicine.
Below is the list of medicines, which have the same composition, strength and form as Zinase-D Tablet , and hence can be used as its substitute.
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Missed Dose instructions

The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.

Overdose instructions

A doctor should be contacted immediately if an overdose of Zinase-D Tablet is suspected. Signs and symptoms of overdose include rashes on the skin, confusion, pain in the chest, blurred vision etc. Immediate medical attention is needed if an overdose is confirmed.
Zinase-D Tablet inhibits an enzyme named Cyclooxygenase which is responsible for the formation of prostaglandin. Prostaglandin is a major contributor to the process of inflammation and pain sensation in the body. It also facilitates the breakdown of proteins and reduces the formation of mucous and relieves inflammation.

Ques: What is Zinase d tablet?

Ans: Zinase D tablet is a medication which has Diclofenac Potassium and Serratiopeptidase as active elements present in it. This medicine performs its action by decreasing the substances in the body that cause swelling and pain, helping the body in breakdown of protein. Zinase D tablet is used to treat condition such as Headache, Sports injuries, Joint stiffness, Gout attacks, Migraine, Air cavities around nose, Ear infections, and Blood clots, etc.

Ques: What is the use of Zinase d tablet?

Ans: Zinase D tablet is a medication, which is used for the treatment and prevention from conditions such as Pain and swelling, Muscles pain, Menstrual cramps, Swelling, Back pain, Bones and joints pain, and Sore throat. Apart from these, it can also be used to treat conditions like Dental pain, Headache, Sports injuries, Joint stiffness, Gout attacks, Migraine, Air cavities around nose, Ear infections, and Blood clots. The patient should inform the doctor about any ongoing medications and treatment before using Zinase D tablet to avoid undesirable effects.

Ques: What are the side effects of Zinase d tablet?

Ans: Zinase D tablet is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Zinase D tablet which are as follows: Gas, Indigestion, Nausea, Diarrhea, Constipation, Headache, Dizziness, Drowsiness, Stuffy nose, Itching, High blood pressure, Bleeding nose, Vomiting, Urge to vomit, Loss of appetite, and Allergy. It is a list of possible side-effects which may occur due to the constituting ingredients of Zinase D tablet.

Ques: Is it safe to use Zinase-D?

Ans: Yes, Zinase D tablet is safe for most of the patients and, in some patients it may cause common unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.

Ques: How long do I need to use zinase d tablet before I see improvement in my condition?

Ans: In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to use this medication.

Ques: At what frequency do I need to use zinase d tablet?

Ans: This medication is generally used once to thrice a day, as the time interval to which this medication has an impact, is around 8 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

Ques: Should I use zinase d tablet empty stomach, before food or after food?

Ans: This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

Ques: What are the instructions for the storage and disposal of zinase d tablet?

Ans: This medication contains salts which are suitable to store only at room temperature, as keeping this medication above that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MD-Pharmacology, MBBS
Table of Content
About Zinase-D Tablet
What are the uses of Zinase-D Tablet
What are the contraindications of Zinase-D Tablet ?
What are the side effects of Zinase-D Tablet ?
Key highlights of Zinase-D Tablet
What are the substitutes for Zinase-D Tablet ?
What are the dosage instructions?
How does medicine works?
Zinase-D Tablet Frequently Asked Questions (FAQs):