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Overview

Vonaz 200 MG Injection

Manufacturer :  United Biotech (P) Ltd
Medicine Composition :  Voriconazole
Prescription vs OTC : Prescription by Doctor required

About Vonaz 200 MG Injection

Vonaz 200 MG Injection is used in the treatment of several serious fungal infections. One of them is invasive aspergillosis, an infection that starts in your lungs and gradually spreads to the other organs through the bloodstream. The medicine can also treat esophageal candidiasis which is a yeast infection causing white patches in your mouth and throat. Apart from this, yeast infections of the skin, kidney, stomach, bladder and wounds can also be cured by Vonaz 200 MG Injection. Belonging to the group of antifungal medicines called triazoles, it works by slowing down the fungal growth that is known to cause the infection.

The dosage of the medication is decided by your doctor based on your general health, the type of infection you are suffering from and your response to the medication. You need to take this drug at least an hour before or after having your meal.

The common side effects of Vonaz 200 MG Injection include agitation, anxiety, headache, dry mouth, loss of appetite, nausea and vomiting. They generally require no medical attention but you can consult your doctor if it keeps bothering you. However, there may be some serious side effects that must be reported at once. It could be:

  • An allergic reaction like skin rashes, itching, hives, swelling of mouth and lips
  • Difficulty in breathing
  • Change in your vision
  • Dark urine and pale-coloured stool
  • Seizures, tremors or hallucinations
  • Blistering, loosening or peeling of skin, including the insides of the mouth
  • Unusual bleeding or bruising
  • Yellowing of the eyes or the skin

Vonaz 200 MG Injection can cause changes in your vision or blurriness. It is advised to avoid driving or using any kind of machinery while you are under this medication. Also, stay away from direct and strong sunlight or wear protective clothing during this time as the medicine can make the skin sensitive to the rays of the sun.

    What are the uses of Vonaz 200 MG Injection

    • Invasive Aspergillosis

      Vonaz 200 MG Injection is used to treat infections in the lungs or immune system caused by Aspergillus strain of fungus.

    • Esophageal Candidiasis

      Vonaz 200 MG Injection helps against infections in the throat caused by Candida strain of fungus.

    • Candidemia

      Vonaz 200 MG Injection is used to cure infections of the blood caused by Candida strain of fungus.

    • Fungal Pneumonia

      Vonaz 200 MG Injection prevents and manages infections that affects the lungs caused by Histoplasma capsulatum and Candida strains of fungi.

    • Fusariosis

      Vonaz 200 MG Injection is helpful in treating infections that affect immunocompromised patients caused by fusarium strain of fungus.

    What are the contraindications of Vonaz 200 MG Injection ?

    • Allergy

      Vonaz 200 MG Injection is not advised for use if you have a known allergy to it.

    • QT Interval prolonging drugs

      Vonaz 200 MG Injection is not suggested for co-administration with medications that can cause specific changes in heart rhythm.

    What are the side effects of Vonaz 200 MG Injection ?

    Key highlights of Vonaz 200 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of about 6 hours.

    • What is the onset of action?

      The top effect of this medicine is usually observed within 1 to 2 hours.

    • Are there any pregnancy warnings?

      This medicine is not suggested for pregnant women unless clearly needed. Consult your doctor to know the potential benefits and risks before taking this medicine.

    • Is it habit forming?

      No habit forming tendencies are reported.

    • Are there any breast-feeding warnings?

      This injection is known to excrete through breast milk. Do not breastfeed if it's necessary to take this medicine. Consult your doctor to know the potential benefits and risks before taking this medicine.

    What are the substitutes for Vonaz 200 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Vonaz 200 MG Injection , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.

    • Are there any overdose instructions?

      Inform your doctor immediately if you are experiencing symptoms of overdose.

    How does this medication work?

    Vonaz 200 MG Injection is an antifungal. It works by inhibiting the synthesis of ergosterol which is an important component of fungi cell membrane by inhibiting cytochrome P-450-mediated 14 alpha-lanosterol demethylation, thus helps in inhibiting the growth of the organism.

      What are the interactions of Vonaz 200 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is not known. It is suggested to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Alprazolam

        Report the usage of either of the drugs to the doctor so that suitable dosage adjustments can be suggested. Monitoring of blood levels might be required in some cases. Symptoms like drowsiness and difficulty in breathing should be reported immediately to the doctor.

        Cisapride

        Use of Vonaz 200 MG Injection while you are taking Cisapride is not recommended. Inform your doctor about the usage of Cisapride so that suitable replacement for Vonaz 200 MG Injection could be prescribed.

        Clopidogrel

        Inform your doctor about the usage of either of these medicines. Dosage adjustments for Clopidogrel might be required in such cases.

        Warfarin

        Usage of Vonaz 200 MG Injection along with Warfarin is recommended only after dosage adjustment. Safety monitoring is a must in such cases. Signs and symptoms like headache, presence of blood in vomit and urine, weakness, unusual bleeding should be reported immediately.

        Atorvastatin

        Use of Vonaz 200 MG Injection with Atorvastatin is not recommended. Inform your doctor about the usage of either of these medicines so that suitable replacement could be suggested. Symptoms like muscle pain and weakness coupled with fever, joint pain and chills should be reported immediately.
      • Interaction with Disease

        Liver Disease

        Vonaz 200 MG Injection should not be used with caution if you suffer from impaired liver functioning.

        Qt Prolongation

        Vonaz 200 MG Injection should be used with caution if you have QT Prolongation.

        Kidney Disease

        Do not use this medication in case you have any active kidney disease.
      • Interaction with Food

        Food

        It is better to take Vonaz 200 MG Injection at least 1 hour before or after food for better absorption of the medicine.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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