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Overview

Tamoxifen

Prescription vs.OTC: Prescription by Doctor required

Different types of breast cancer thrive on estrogen to grow and spread. Tamoxifen helps to block the functioning of this estrogen in a cancer that turn metastasized. It also helps to lower the chances of breast cancer in women with a high risk of developing it.

Tamoxifen is not to be taken if you?re pregnant as it could potentially harm the baby. If you have a history of liver disease, cataract, stroke, or high triglycerides, tell your doctor. Your doctor may ask you to undergo mammograms and breast self exams in order to find out if the medicine is not causing harm.

Measure Tamoxifen using proper measuring spoons or cups. It can be taken with or without food, according to the doctor?s directions. While taking this medicine, you may need to take several blood tests. If you have surgery or any other medical test coming up, you may need to stop using it for a short period.

Tamoxifen increases your chances of developing a blood clot or a stroke. If you have a breast lump, unusual bleeding from the vagina, blurred vision, liver problems and hot flashes, call your doctor immediately.

In addition to its intended effect, Tamoxifen may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Nolvadex 10mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Are there any breast-feeding warnings?
Nolvadex 10mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
Evafem 2Mg Tablet
Premarin 1.25Mg Tablet
Acitrom 4Mg Tablet
Acenomac 3Mg Tablet

Popular Questions & Answers

Taking tamoxifen for a long time about 2-3 yrs, how it affects breast cancer patient with Er+/Pr+? Does it affects the future pregnancy related issues?

MD - Radiothrapy, MBBS
Oncologist, Pune
Tamoxifen should be taken for at least 5 years. It will reduce the chances of recurrence of disease and will improve survival. You can plan pregnancy. Tamoxifen should be stopped if pregnancy is detected.
1 person found this helpful

My wife had breast cancer and she went into remission this February 2017. She was diagnosed around mid November 2014. My wife just turned 39 and had ER PR positive tumor which was destroyed using radiotherapy in New York. As such she has been on Tamoxifen since she was diagnosed but then stopped it as she went into remission. We want to have children and were wondering which will be the best kind of doctor and some recommendations too since this is not a very usual case. Thank you in advance,

MBBS, MS - General Surgery, FBD (Fellowship in Breast Diseases), UICC Fellowship
Oncologist, Pune
Planning a family in a breast cancer patient is not advisable for 2 years (counted from last day of treatment). As chances of relapse are higher in initial 2 years. So she can plan her pregnancy according to your gynaec. But she has to stop tamoxifen as it has got teratogenic effect on baby if she conceive.

Sir it is true that luteolin that present in carrots is more powerful than tamoxifen to control Harmon receptors in breast cancer?

MBBS, MS - General Surgery, FBD (Fellowship in Breast Diseases), UICC Fellowship
Oncologist, Pune
Tamoxifen is a prooved drug for hormone positive breast cancer. So according to the studies and data which is available tamoxifen is better for hormone positive breast cancer as hormonal treatment.

As you said liposuction is not the permanent solution for gynecomastia. Then please let me know how do I, suffering from gynecomastia, control it. I tried tamoxifen as well but stopped taking it after not getting positive signs.

MCh - Plastic and Reconstructive Surgery
Cosmetic/Plastic Surgeon, Bangalore
Hello. Liposuction and the gland removal (depending upon the amount of fatty and glandular tissue in the region) is the standard treatment of choice for gynecomastia. It will reduce the appearance of it drastically and the garment worn after the procedure also brings the chances of recurrence to almost zero. Please consult a plastic surgeon for the same and he'll give you a more better idea of the procedure.

Hi doctor, I am 32 years old and trying to conceive from last 5 months. I have controlled hypothyroidism and survivor of breast cancer too. I had miscarriages before detecting breast cancer. Later I was on tamoxifen for five years. Now doctors allowed me to conceive but I am unable to conceive. My all reports are normal. Pls suggest me so that I can conceive fast.

BHMS
Homeopath, Chennai
Hi doctor,
I am 32 years old and trying to conceive from last 5 months. I have controlled hypothyroidism and survivor...
Infertility is not a disease, but a derangement- a condition where the couple is unable to conceive. The patient may have tried the help of ART=Assisted Reproductive Treatment, starting from simple medication to expensive and invasive procedures, IVF, ICSI, PGD etc. These can lead to anything from derangement in the normal physiology, to gross irreversible pathology, leading to iatrogenic complications. Numerous infertility cases have been treated successfully with homeopathic medicine and they have been reported on homeopathic medical journals. All these cases show how homeopathic treatment restored overall health and helped women, who were previously infertile conceive and have a healthy pregnancy and baby. Homeopathic remedies can help infertile couples achieve pregnancy even if there are physical conditions that can prevent the implantation of the embryo contributing to infertility or miscarriages You can easily take an online consultation for further treatment guidance and permanent cure without any side effects.

Popular Health Tips

Fatty Liver - What To Know About It?

MBBS, MD - General Medicine, DM - Gastroenterology, Fellowship in Advanced Endoscopy
Gastroenterologist, Mumbai
Fatty Liver - What To Know About It?

Fatty liver is a condition where excess fat is deposited on this organ. Also called as steatosis, this condition happens when more than 5- 10 percent of the weight of the liver is made up of fat. Fatty liver is a common condition among people. A study from coastal regions of India found ~ 25% of healthy persons had patients had fatty liver on ultrasound. It can occur at all ages including childhood, highest prevalence is in 40–50 year age group. Prevalence more in patient who are obese and in diabetic patients.

Types of Fatty Liver

1 Alcoholic fatty liver: This condition occurs when there is a heavy consumption of alcohol. Gastroenterologists recommend abstention from alcohol for this condition to subside. If the patient continues to consume alcohol, then liver cirrhosis may develop.

2 Non alcoholic fatty liver (NAFL): One may develop a fatty liver even if one is not an alcoholic. The liver in some cases is unable to process the fat in cells causing them to build-up on the organ.

When more than 10% of the liver is made of fat then this condition is called Non Alcoholic Fatty Liver (NAFL).

Non alcoholic steatohepatitis (NASH): When fatty liver is associated with inflammation in liver patient is said to be having Non alcoholic steatohepatitis. NASH is a more advanced stage of NAFLD, and has a higher risk of progressing to liver cirrhosis or hepatocellular carcinoma (HCC). These condition display symptoms like jaundice, vomiting, nausea, loss of appetite and abdominal pain. Blood test (LFT) shows raised enzymes level. Approx 5-8% of the Indian population has NASH. Consult a doctor if you are experiencing any of these symptoms.

3 Fatty liver during pregnancy: Occurring mainly in the third trimester, the symptoms of this condition are vomiting, nausea, pain the right part of the abdomen and jaundice.

Symptoms

During the early stages (fatty liver) of the disease, patients usually have no symptoms directly related to liver disease. However, people may experience a vague abdominal discomfort. If their liver is inflamed (NASH) then they may display symptoms of poor appetite, weight loss, pain in the abdomen and disorientation.

What causes fatty liver?

The most common cause of fatty liver is alcoholism. When the human liver is unable to metabolize fat fast enough or when there is an excess accumulation of fat on the liver cells then the liver becomes fatty. However, intake of high-fat foods may not result in a fatty liver.

Predisposing factor:

  1. Diabetes mellitus
  2. Obesity or being overweight
  3. Hyperlipidemia or the condition where there are high levels of fat in the blood
  4. Genetic reasons
  5. Rapid loss of weight
  6. Drugs: Aspirin, steroids, tamoxifen, tetracycline etc. cause side effects which also leads to fatty liver
  7. Nutritional status (eg, overnutrition, severe malnutrition, total parenteral nutrition [TPN], or starvation diet)
  8. Other health problems (eg, Hepatitis C infection, celiac sprue and Wilson disease).

In case you have a concern or query you can always consult an expert & get answers to your questions!

3180 people found this helpful

Fatty Liver: Types, Causes and Symptoms

MBBS, MD - Internal Medicine , DM - Gastroenterology
Gastroenterologist, Bangalore
Fatty Liver: Types, Causes and Symptoms

Fatty liver is a condition where excess fat is deposited on this organ. Also called as steatosis, this condition happens when more than 5- 10 percent of the weight of the liver is made up of fat.

Fatty liver is a common condition among people. A study from coastal regions of India found ~ 25% of healthy persons had patients had fatty liver on ultrasound.

It can occur at all ages including childhood, highest prevalence is in 40–50 year age group. Prevalence more in patient who are obese and in diabetic patients.

Types of Fatty Liver

1 Alcoholic fatty liver: This condition occurs when there is a heavy consumption of alcohol. Gastroenterologists recommend abstention from alcohol for this condition to subside. If the patient continues to consume alcohol, then liver cirrhosis may develop.

2 Non alcoholic fatty liver (NAFL): One may develop a fatty liver even if one is not an alcoholic. The liver in some cases is unable to process the fat in cells causing them to build-up on the organ.

When more than 10% of the liver is made of fat then this condition is called Non Alcoholic Fatty Liver (NAFL).

Non alcoholic steatohepatitis (NASH): When fatty liver is associated with inflammation in liver patient is said to be having Non alcoholic steatohepatitis. NASH is a more advanced stage of NAFLD, and has a higher risk of progressing to liver cirrhosis or hepatocellular carcinoma (HCC). These condition display symptoms like jaundice, vomiting, nausea, loss of appetite and abdominal pain. Blood test (LFT) shows raised enzymes level. Approx 5-8% of the Indian population has NASH. Consult a doctor if you are experiencing any of these symptoms.

3 Fatty liver during pregnancy: Occurring mainly in the third trimester, the symptoms of this condition are vomiting, nausea, pain the right part of the abdomen and jaundice.

Symptoms

During the early stages (fatty liver) of the disease, patients usually have no symptoms directly related to liver disease. However, people may experience a vague abdominal discomfort. If their liver is inflamed (NASH) then they may display symptoms of poor appetite, weight loss, pain in the abdomen and disorientation.

What causes fatty liver?

The most common cause of fatty liver is alcoholism. When the human liver is unable to metabolize fat fast enough or when there is an excess accumulation of fat on the liver cells then the liver becomes fatty. However, intake of high-fat foods may not result in a fatty liver.

Predisposing factor:

1. Diabetes mellitus

2. Obesity or being overweight

3. Hyperlipidemia or the condition where there are high levels of fat in the blood

4. Genetic reasons

5. Rapid loss of weight

6. Drugs: Aspirin, steroids, tamoxifen, tetracycline etc. cause side effects which also leads to fatty liver

7. Nutritional status (eg, overnutrition, severe malnutrition, total parenteral nutrition [TPN], or starvation diet)

8. Other health problems (eg, Hepatitis C infection, celiac sprue and Wilson disease)

In case you have a concern or query you can always consult an expert & get answers to your questions!

3696 people found this helpful

Dyspareunia - Diagnosis and Treatment!

Bachelor of Ayurveda, Medicine and Surgery (BAMS), BHMS, MCSEPI
Sexologist, Pune
Dyspareunia - Diagnosis and Treatment!

Pain during or after sexual intercourse is known as dyspareunia. Although this problem can affect men, it is more common in women. Women with dyspareunia may have pain in the vagina, clitoris or labia. There are numerous causes of dyspareunia, many of which are treatable. 

Common causes include the following:

  1. Vaginal dryness
  2. Atrophic vaginitis, a common condition causing thinning of the vaginal lining in postmenopausal women
  3. Side effects of drugs such as antihistamines and tamoxifen (Nolvadex and other brands)
  4. An allergic reaction to clothing, spermicides or douches
  5. Endometriosis, an often painful condition in which tissue from the uterine lining migrates and grows abnormally inside the pelvis
  6. Inflammation of the area surrounding the vaginal opening, called vulvar vestibulitis
  7. Skin diseases, such as lichen planus and lichen sclerosus, affecting the vaginal area
  8. Urinary tract infections, vaginal yeast infections, or sexually transmitted diseases
  9. Psychological trauma, often stemming from a past history of sexual abuse or trauma.

Symptoms of Dyspareunia:
Women with dyspareunia may feel superficial pain at the entrance of the vagina or deeper pain during penetration or thrusting of the penis. Some women also may experience severe tightening of the vaginal muscles during penetration, a condition called vaginismus.

Diagnosis:
Your health practitioner will check for the following things

  1. If there was ever a time you had painless intercourse or if you have always had dyspareunia
  2. If you have enough natural lubrication and if your symptoms improve when you use commercially available lubricants
  3. About your sexual history (to help assess your risk for sexually transmitted infections)
  4. If you have ever been sexually abused or had a traumatic injury involving your genitals.

Treatment:

  1. Lubrication with an over-the-counter lubricant such as K-Y jelly.
  2. Antifungal medication(if you have any kind of fungal infection)
  3. Sitz baths for removing the inflammation
  4. For skin diseases affecting the vaginal area, lichen sclerosus and lichen planus often improve with steroid creams.
  5. Therapies include topical estrogen cream, low-dose pain medications, and physical therapy with biofeedback to lower the muscle tension in the pelvic floor
  6. Surgeries can also be prescribed for abnormal growths

For dyspareunia that has no apparent physical cause or has lasted for months or years, you may need psychological counseling to address stress or anxiety regarding sexual intercourse.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4723 people found this helpful

Types, Causes and Symptoms of Fatty Liver

MBBS, M.S., MCh - Surgical Gastroenterology/G.I. Surgery
Gastroenterologist, Agra
Types, Causes and Symptoms of Fatty Liver

Fatty liver is a condition where excess fat is deposited on this organ. Also called as steatosis, this condition happens when more than 5- 10 percent of the weight of the liver is made up of fat.

Fatty liver is a common condition among people. A study from coastal regions of India found ~ 25% of healthy persons had patients had fatty liver on ultrasound.

It can occur at all ages including childhood, highest prevalence is in 40–50 year age group. Prevalence more in patient who are obese and in diabetic patients.

Types of Fatty Liver

1 Alcoholic fatty liver: This condition occurs when there is a heavy consumption of alcohol. Gastroenterologists recommend abstention from alcohol for this condition to subside. If the patient continues to consume alcohol, then liver cirrhosis may develop.

2 Non alcoholic fatty liver (NAFL): One may develop a fatty liver even if one is not an alcoholic. The liver in some cases is unable to process the fat in cells causing them to build-up on the organ.

When more than 10% of the liver is made of fat then this condition is called Non Alcoholic Fatty Liver (NAFL).

Non alcoholic steatohepatitis (NASH): When fatty liver is associated with inflammation in liver patient is said to be having Non alcoholic steatohepatitis. NASH is a more advanced stage of NAFLD, and has a higher risk of progressing to liver cirrhosis or hepatocellular carcinoma (HCC). These condition display symptoms like jaundice, vomiting, nausea, loss of appetite and abdominal pain. Blood test (LFT) shows raised enzymes level. Approx 5-8% of the Indian population has NASH. Consult a doctor if you are experiencing any of these symptoms.

3 Fatty liver during pregnancy: Occurring mainly in the third trimester, the symptoms of this condition are vomiting, nausea, pain the right part of the abdomen and jaundice.

Symptoms

During the early stages (fatty liver) of the disease, patients usually have no symptoms directly related to liver disease. However, people may experience a vague abdominal discomfort. If their liver is inflamed (NASH) then they may display symptoms of poor appetite, weight loss, pain in the abdomen and disorientation.

What causes fatty liver?

The most common cause of fatty liver is alcoholism. When the human liver is unable to metabolize fat fast enough or when there is an excess accumulation of fat on the liver cells then the liver becomes fatty. However, intake of high-fat foods may not result in a fatty liver.

Predisposing factor:

1. Diabetes mellitus

2. Obesity or being overweight

3. Hyperlipidemia or the condition where there are high levels of fat in the blood

4. Genetic reasons

5. Rapid loss of weight

6. Drugs: Aspirin, steroids, tamoxifen, tetracycline etc. cause side effects which also leads to fatty liver

7. Nutritional status (eg, overnutrition, severe malnutrition, total parenteral nutrition [TPN], or starvation diet)

8. Other health problems (eg, Hepatitis C infection, celiac sprue and Wilson disease)

In case you have a concern or query you can always consult an expert & get answers to your questions!

3450 people found this helpful

Fatty Liver - Know Its Types!

MBBS, DNB ( General Surgery ), MNAMS - General Surgery
Gastroenterologist, Pune
Fatty Liver - Know Its Types!

Fatty liver is a condition where excess fat is deposited on this organ. Also called as steatosis, this condition happens when more than 5- 10 percent of the weight of the liver is made up of fat.

Fatty liver is a common condition among people. A study from coastal regions of India found ~ 25% of healthy persons had patients had fatty liver on ultrasound.

It can occur at all ages including childhood, highest prevalence is in 40–50 year age group. Prevalence more in patient who are obese and in diabetic patients.

Types of Fatty Liver

1 Alcoholic fatty liver: This condition occurs when there is a heavy consumption of alcohol. Gastroenterologists recommend abstention from alcohol for this condition to subside. If the patient continues to consume alcohol, then liver cirrhosis may develop.

2 Non alcoholic fatty liver (NAFL): One may develop a fatty liver even if one is not an alcoholic. The liver in some cases is unable to process the fat in cells causing them to build-up on the organ.

When more than 10% of the liver is made of fat then this condition is called Non Alcoholic Fatty Liver (NAFL).

Non alcoholic steatohepatitis (NASH): When fatty liver is associated with inflammation in liver patient is said to be having Non alcoholic steatohepatitis. NASH is a more advanced stage of NAFLD, and has a higher risk of progressing to liver cirrhosis or hepatocellular carcinoma (HCC). These condition display symptoms like jaundice, vomiting, nausea, loss of appetite and abdominal pain. Blood test (LFT) shows raised enzymes level. Approx 5-8% of the Indian population has NASH. Consult a doctor if you are experiencing any of these symptoms.

3 Fatty liver during pregnancy: Occurring mainly in the third trimester, the symptoms of this condition are vomiting, nausea, pain the right part of the abdomen and jaundice.

Symptoms

During the early stages (fatty liver) of the disease, patients usually have no symptoms directly related to liver disease. However, people may experience a vague abdominal discomfort. If their liver is inflamed (NASH) then they may display symptoms of poor appetite, weight loss, pain in the abdomen and disorientation.

What causes fatty liver?

The most common cause of fatty liver is alcoholism. When the human liver is unable to metabolize fat fast enough or when there is an excess accumulation of fat on the liver cells then the liver becomes fatty. However, intake of high-fat foods may not result in a fatty liver.

Predisposing factor:

  1. Diabetes mellitus
  2. Obesity or being overweight
  3. Hyperlipidemia or the condition where there are high levels of fat in the blood
  4. Genetic reasons
  5. Rapid loss of weight
  6. Drugs: Aspirin, steroids, tamoxifen, tetracycline etc. cause side effects which also leads to fatty liver
  7. Nutritional status (eg, overnutrition, severe malnutrition, total parenteral nutrition [TPN], or starvation diet)
  8. Other health problems (eg, Hepatitis C infection, celiac sprue and Wilson disease)

In case you have a concern or query you can always consult an expert & get answers to your questions!

3463 people found this helpful