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Rf Compound 450 Mg/300 Mg Tablet

Manufacturer: Sunij Pharma Pvt Ltd
Medicine composition: Rifampicin, Isoniazid
Prescription vs.OTC: Prescription by Doctor required

Rf Compound 450 Mg/300 Mg Tablet belongs to the rifamycin group of antibiotics and is used to treat numerous bacterial infections.This includes leprosy, tuberculosis and Legionnaire's disease. This medicine is administered either by mouth or intravenously. It works by interfering and preventing the production of RNA by bacteria.

Common side effects of this drug include diarrhoea, nausea, vomiting and loss of appetite. It often turns the colour of sweat, urine and tears red or orange. Liver problems or allergic reactions may also occur as side effects. Even though its safety during pregnancy is not known, Rf Compound 450 Mg/300 Mg Tablet is part of the recommended treatment of tuberculosis during pregnancy.

People with hypersensitivity to Rf Compound 450 Mg/300 Mg Tablet and jaundice are not recommended this medicine. It should be used with caution in people with a history of alcoholism and hepatic and renal impairment. Elderly, malnourished patients, children below 2 years of age, pregnant or breastfeeding women need to take this medicine in lower doses.

This medicine is best taken on an empty stomach 1 hour before or 2 hours after a meal. Your dosage will be as prescribed by your doctor where your age, weight and medical condition will be taken into consideration.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Pulmonologist before using this medicine.

tuberculosis (tb)
In addition to its intended effect, Rf Compound 450 Mg/300 Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Muscle pain.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Cavidin 450mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Cavidin 450mg tablet is probably safe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?
Caution to be advised in patients with impaired renal function.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Rf Compound 450 Mg/300 Mg Tablet , and hence can be used as its substitute.
Lincoln Pharmaceuticals Ltd
Cadila Pharmaceuticals Ltd
Lupin Ltd
Lupin Ltd
Macleods Pharmaceuticals Pvt Ltd
Prayas Pharmaceuticals
Albert David Ltd
Marc Laboratories Pvt Ltd
Indica Laboratories Pvt Ltd
Concept Pharmaceuticals Ltd
Unichem Laboratories Ltd
Marc Laboratories Pvt Ltd
Unichem Laboratories Ltd
Euphoric Pharmaceuticals Pvt Ltd
Morepen Laboratories Ltd
Unichem Laboratories Ltd
Stanford Biotech Pvt Ltd
Ind Swift Laboratories Ltd
Sun Pharmaceutical Industries Ltd
Acme Pharmaceutical
Lancer Health Care Pvt Ltd
Overseas Healthcare Pvt Ltd
Alkem Laboratories Ltd
Aarpik Pharmaceuticals Pvt Ltd
Biological E Ltd
Themis Medicare Ltd
West-Coast Pharmaceutical Works Ltd
Zydus Cadila
Apex Laboratories Pvt Ltd
Reliance Formulation Pvt Ltd
Lark Laboratories Ltd
Indoco Remedies Ltd
Alde Medi Impex Ltd
Zee Laboratories
Marc Laboratories Pvt Ltd
Zee Laboratories
Kentreck Laboratories Pvt Ltd
Glaxo SmithKline Pharmaceuticals Ltd
Cadila Pharmaceuticals Ltd
Ajanta Pharma Ltd
Aristo Pharmaceuticals Pvt Ltd
East African India Remedies Pvt Ltd
Sun Pharmaceutical Industries Ltd
Alkem Laboratories Ltd
Shrinivas Gujarat Laboratories Pvt Ltd
Sun Pharmaceutical Industries Ltd
Are there any missed dose instructions?
If you miss a dose of Rifampicin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Rf Compound 450 Mg/300 Mg Tablet inhibits bacterial RNA polymerase which is the enzyme responsible for the transcription of DNA. Rifampicin binds and prevents RNA synthesis by blocking elongation and synthesis of bacterial proteins. It blocks the bond between nucleotides in the RNA backbone.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Medicine
What are you using Rf Compound 450 Mg/300 Mg Tablet for?
tuberculosis and Legionnaire's disease
Muscle pain
How much was the improvement?
How long did it take before seeing improvement?
More than 2 days
How frequently did you take this medicine?
Not taking on daily level
How did you take this medicine?
With or without food
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Feels BP fluctuations. Normally 135 /90 but during any meeting or cross questioning I feel nervous and hyper. Mouth dryness and sweating in forehead. Feels tired and drowsiness.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Bijapur
Feels BP fluctuations. Normally 135 /90 but during any meeting or cross questioning I feel nervous and hyper. Mouth d...
Dear Lybrate user BP fluctuation happens if there is wave of pressure and tension in mind. Do not feel nervous and depressive, face the situations and conditions by calm and cool. Practice pranayama and yoga regularly. Drink sufficient water every day. Maintain balanced diet and adequate sleep. You can take swamala compound 1tsp twice a day.

I'm having the problem of itching from the past 5 months. Have consulted 3 different skin specialists, each one diagnosed differently, treated differently but hardly any benefit. 1st one diagnosed it as dermatitis and treated with Fluconazole Methylprednisolone. Problem did not subside. 2nd one diagnosed it as a different kind of dermatitis and treated with Itraconazole. Problem did not subside. 3rd one diagnosed it as scabies and treated with different compounds. Problem did not subside. Various creams - Itraconazole, Clobetasol, Neomycin etc. Tried. Problem subsides but after some time recurs. Sweating causes the itching to spread all over body. Presently, main affected parts are Groin, lower back, belt line, below knees all along lower limb. Itching causes a lot of discomfort especially during nights.

Homeopath, Mumbai
I'm having the problem of itching from the past 5 months. Have consulted 3 different skin specialists, each one diagn...
Hello lybrate-user, I assume from reading that you are suffering from Pruritus Intriago meaning itching usually under the skin fold which usually caused due to fungal infections. Ensure you take bath twice daily and remove all unwanted hairs and keep the body dry and wear a loose fitting clothing. These precautions are other the medication prescribed by the doctors. You continue to suffer from fungal infections is because of repeated fungal infections. With above suggestions I think it will help. If your itching is not coming under control then I would suggest you go for full medical check-up to investigate any underlying systematic diseases. Alternatively you can consult me Homoeopathic treatment if your problems is not solved. Hopefully your questions is answered.

30 year female recently started complaining of joint pains and stiffness all over the body. Specially lower back, knees, wrist, and fingers. Though there is no visible swelling in any of the joints. Following tests were done with these results: CRP (quantitative) = 0.6 RF = 1.00 TLC = 6.95 DLC-neutrophil = 58 Lymphocytes = 33 Monocyte = 05 Eosinophil = 04 Basophil = 00 ESR = 08 Based on these result RA was diagnosed. Would like to have your second opinion.

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
30 year female recently started complaining of joint pains and stiffness all over the body. Specially lower back, kne...
Multiple Joint Pains / Early morning pain It is called as Rheumatic arthritis. If your pain is more in the distal joints, ie. In the upper limbs if the pain is present in the fingers/wrist and in the lower limbs it the pain is present in the toes/ ankle, then we shall definitely say it is Rheumatic arthritis. Wear elbow brace and wrist brace which will make her to feel warm and that will make the joints become firm. Hot water fermentation will help. Knee cap will also help to prevent the damaged cartilages If your pain is more in the distal joints, ie. In the upper limbs if the pain is present in the fingers/wrist and in the lower limbs it the pain is present in the toes/ ankle, then we shall definitely say it is Rheumatic arthritis. Which joints you have pain? If your proximal joints (ie. Shoulder, hip & knee has pain) then you can pour hot (warm) water in that area to reduce the inflammation. If you have pain in the distal joints ie. Wrist, fingers, ankle, toes then you can wear either elbow brace or wrist brace which will help you to feel warm and very protective. And also immerse the distal joints in the hot water tub which will help you to reduce the pain. Consult the near by physiotherapy clinic and also consult a general physician to check with your ESR levels to check whether you have inflammation.
2 people found this helpful

Hello sir/ma'm, My mom is 50 years old, she is suffering from swelling of mouth and also suffering from knee pain and back pain for last two years, I consulted by many orthopedic doctors bt no benefits still suffering, now I need suggestion for doctors that by which specialist doctor I can consult to mom, so please suggest me better doctor and specialist for her. thanks.

Internal Medicine Specialist, Kendujhar
Hello sir/ma'm, My mom is 50 years old, she is suffering from swelling of mouth and also suffering from knee pain and...
Hello, Thanks for your query on Lybrate "As" per your clinical history is concerned please follow like this - Do a physical examination by your Doctor (rheumatologist) and do few tests like (CBC with differential, ESR,RF factor and anti-CCP test)to confirm diagnosis. Do take few lifestyle modifications like this - 1) Do exercise regularly. Gentle exercise can help strengthen the muscles around joints, and try to avoid exercising tender, injured or severely inflamed joints. 2) Apply heat or cold. Heat can help ease your pain and relax tense, painful muscles. Cold may dull the sensation of pain. Cold also has a numbing effect and decreases muscle spasms. 3) Find ways to cope with pain by reducing stress in your life. Techniques such as guided imagery, distraction and muscle relaxation can all be used to control pain. Hope that helps Follow me with detailed reports.
1 person found this helpful

Popular Health Tips

Health Benefits of Kiwi

Sexologist Clinic
Sexologist, Faridabad
Health Benefits of Kiwi

1. High Source of Vitamin C

If you thought that lemons and oranges were the highest sources of Vitamin C, then think again! According to the nutritional break-up of kiwi fruit, per 100 grams contain 154 percentage of Vitamin C, which is almost twice that of lemons and oranges. Vitamin C acts as powerful antioxidant, eliminating free radicals that could cause inflammation or cancer. It also helps in boosting the immunity of the body against harmful pathogens.

2. Sleep Inducer

Having trouble sleeping? According to a research done by Taipei Medical University, “Numerous studies have revealed that kiwi fruit contains many medicinally useful compounds, among which antioxidants and serotonin may be beneficial in the treatment of sleep disorders.” It is said that having two kiwi fruits one hour before bedtime can help immensely in inducing sleep.

3. Good Source of Dietary Fiber

This exotic fruit is loaded with dietary fiber, which helps in the prevention of numerous diseases. According to a study done by the University of Leeds, “Increasing consumption of fibre-rich foods can lower risks of both cardiovascular disease (CVD) and coronary heart disease (CHD).” According to researchers at the University of Massachusetts Medical School, high fiber foods keep one full for longer and control metabolic markers like blood pressure, cholesterol and blood sugar. It also facilities weight loss and is often recommended to diabetics.

4. Helps in Digestion

Kiwi fruit contains an enzyme known as actinidain which is known for its protein dissolving properties, similar to that of papain in papaya. This is the reason why it is commonly used as a meat tenderiser. Moreover, it helps in the digestion of proteins in the body and is also known to help patients suffering from irritable bowel syndrome.

8 people found this helpful

Cholesterol - 10 Foods That Help You Lower The Levels!

M.SC In Clinical Nutrition & Dietetics, PGCDE Certifies Diabetes Educator
Dietitian/Nutritionist, Delhi
Cholesterol - 10 Foods That Help You Lower The Levels!

Food plays a vital role in lowering the cholesterol apart from timely medication. Here is a list of 10 foods that contribute to a great extent in lowering the cholesterol level:

  1. OatsChanging the morning meal is the first action you should take. Oatmeal can bring down the LDL level to a staggering 5.3 percent in a matter of 6 weeks. It contains beta-glucan, which is capable of absorbing the LDL present in the blood.
  2. Red wineYou can cheer to reduced cholesterol with a glass of red wine in hand. A study conducted by the Universidad Complutense de Madrid in Spain found that red wine can reduce the cholesterol level up to 9 percent owing to a vital component known as Rioja present in it.
  3. Salmon Fish: Fatty and salmon fish contains Omega-3 fatty acids. They are known to be extremely effective for diseases such as dementia, cardiovascular diseases and much more. A study conducted by the Loma Linda University found that Omega-3 can increase the HDL by up to 4 percent. 
  4. Nuts: Nuts can reduce the cholesterol by up to 9.3 percent, a study by the American Journal of Clinical Nutrition revealed. 1.5 oz of regular consumption of nuts greatly helps in bringing down cholesterol. Since nuts are very rich in protein, portion control is necessary to refrain putting on weight.
  5. BeansA research conducted by the Arizona State Polytechnic University revealed that adding beans to soup can bring down the LDL up to 8 percent. Owing to their rich fibre content, they effectively absorb cholesterol. Some of the beans that can be tried include kidney, black and pinto beans.
  6. Cocoa: A study conducted by the AJCN reported that the daily intake of cocoa increases the HDL by over 20 percent in 3 months. Due to its high antioxidant content, it streamlines the blood flow and doesn’t let platelets stick together.
  7. Garlic2-3 cloves of garlic per day can dramatically reduce cholesterol-limiting LDL into the artery. It can prevent other conditions such as blood pressure, infections and blood clotting. Garlic can be consumed with any regular dish. 
  8. Olive oilOlive oil has multiple health benefits. It contains a compound known as MUFAs that lowers cholesterol and helps to get rid of abdomen fats. You can use it with salads, roast vegetables and marinate chicken.
  9. AvocadoAvocado contains monounsaturated fat that helps to raise the level of HDL and lower the LDL in the body. It contains Beta-sitosterol that absorbs cholesterol and brings down the count of it in the body. Owing to its high-calorie content, portion size should be looked into.
  10. Margarine: Two margarine can lower the LDL level up to 14 %. They are capable of absorbing cholesterol from the bile. It can be consumed with toast in the morning or as a snack in the evening.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3456 people found this helpful

Thyroid Treatment in Homeopathy!

MD - Homeopathy, BHMS
Homeopath, Pune
Thyroid Treatment in Homeopathy!

One of the fastest growing disorders in modern times is the malfunction of the Thyroid. The statistics show that the Thyroid condition is the most under-diagnosed health problem. There are millions of people suffering from Thyroid problems, but only a few out of those are diagnosed and treated, see positive results using Thyroid medications. Often the Thyroid levels appear normal with lab, yet the individuals struggle with the symptoms of Thyroid problem. The Thyroid is one of several glands in the endocrine system, located in the front of the neck. The glands of the endocrine system control many of the body’s functions through chemical substances called hormones. The hormones produced by the Thyroid gland regulate how the body cells use energy and how fast the body’s metabolism work. This gland also affects the rate of growth of the hair and bones, the body over weight, temperature and energy level as well as the function of the heart and digestive system.

Homeopathy For Thyroid

In homeopathy, there is no general treatment and no specific remedies for any disease. Rather, treatment is individualized. This means that the presentation of a disease in each patient is considered unique, and the homeopath prescribes remedies after an intimate consultation with each patient.

During the homeopathy consultation, the homeopath considers more than just the symptoms of the disease. He also considers the disposition and constitution of the patient. This means that the homeopath approaches treatment by weighing the physical, mental and emotional states of the patient as well as the symptoms of the disease. This approach leads to the prescription of a unique set of remedies for each patient. Therefore, two patients suffering from the same disease may receive two different sets of remedies from the same homeopath. 

The second principle of homeopathy is the use of poisons to treat diseases. Homeopathy employs watered down poisons to treat disorders. A similar principle is used in the production of vaccines in conventional medicine. If a natural compound may cause certain symptoms and signs in high doses, homeopaths believe very low doses of the dilute solution of the compound can also relieve the same symptoms and signs.

Despite the apparent confusion and the seeming lack of coherence, homeopathy has been largely successful and in some cases, its practices and remedies can be backed up with scientific evidence. Even though homeopathy does not provide specific remedies for any disease, it is still possible to draw up a list of commonly prescribed homeopathic remedies for any disease. In case you have a concern or query you can always consult an expert & get answers to your questions!

3665 people found this helpful

20 Health Benefits Of Til Gud

DHMS (Diploma in Homeopathic Medicine and Surgery)


Sesame seeds are full of high quality protein. Protein makes up 20 percent of the seed with 4.7 grams of protein per ounce.​


Sesame seeds contain magnesium and other nutrients. Sesame oil has been shown to prevent diabetes, and it can also improve plasma glucose in hypersensitive diabetics.


The same study above reveals how sesame oil lowers blood pressure in diabetics. Sesame seeds are full of magnesium—a key nutrient known to help lower blood pressure.


Sesame helps lower cholesterol levels because it contains phytosterols that block cholesterol production. Black sesame seeds are especially high in phytosterols.


The high fiber content of sesame seeds helps the intestines with elimination.


The high zinc content helps produce collagen, giving skin more elasticity and helping repair damaged body tissues. Regular use of sesame oil can reduce skin cancer. Learn more about Sesame Benefits For Your Skin.


Sesame seed oil can help heart health by preventing atherosclerotic lesions with the antioxidant and anti-inflammatory compound known as sesamol.


Sesame seeds contain anti-cancer compounds including phytic acid, magnesium and phytosterols. Sesame seeds have the highest phytosterol content of all seeds and nuts.



Sesame seeds contain the stress-relieving minerals magnesium and calcium. Sesame also contains the calming vitamins thiamin and tryptophan that help produce serotonin, which reduces pain, assists moods and helps you sleep deeply.


Black sesame seeds are particularly rich in iron. They’re highly recommended for those with anemia and weakness.


Sesamol in sesame seeds and sesame oil has been shown to protect against DNA damage caused by radiation.


The high copper content in sesame seeds prevents and relieves arthritis, and strengthens bones, joints and blood vessels.


Sesame helps protect you from alcohol’s impact on your liver, helping you maintain healthy liver function.


Sesame seed oil prevents harmful ultraviolet rays of the sun from damaging your skin, preventing the appearance of wrinkles and pigmentation.


A handful of sesame seeds contains more calcium than a glass of milk. The high zinc content of sesame seeds also boost bone mineral density.


A sesame oil massage improves growth in infants and improves sleep. Rashes on a baby’s skin—especially where the diaper is—can be protected by rubbing sesame oil on the skin. As a bonus, sesame also helps reverse dry skin.


In traditional Chinese medicine, there is a relationship between the liver and eyes. The liver sends blood to the eyes to support functioning. Black sesame seeds are the best for this.


Oil pulling has been used for oral health for thousands of years in Ayurveda to reduce dental plaque, whiten your teeth and boost overall health.


The magnesium in sesame seeds helps prevent respiratory disorders by preventing airway spasm and asthma.


Sesame seed oil is full of the nutrients needed for a healthy scalp and hair. See how to use sesame oil in your hair here.

Sesame seeds deserve to be highly honored as an affordable food that deeply nourishes the body on many levels.

3 people found this helpful

Dermal Fillers - Getting a Facelift!!

MD - Skin,VD & Leprosy, MBBS
Dermatologist, Patna
Dermal Fillers - Getting a Facelift!!

Dermal fillers (also called injectable facial fillers) are soft tissues injected into the skin. This is done to help fill up the hollowed and flattened facial features, smoothen folds and wrinkles, fatten the cheeks, correct bumps on the nose and forehead and increase the elasticity of the skin.With advancing age, your face loses firmness and volume of the facial muscles. A facelift is a non-surgical procedure which helps to restore and create healthier and more youthful features. Here are the things you should know about getting a liquid facelift with dermal fillers:

  1. The typically used dermal fillers are Juvederm, Reyslatine, Emervel, Radiesse and Belotero. There are several different kinds of fillers that are of different consistencies and volume.
  2. Fillers are composed of collagen fibers and hyaluronic acids (these come from organic sources) and a few biosynthetic compounds.
  3. A single treatment session takes about half to an hour.
  4. The swelling takes about 2 - 3days to subside and in many cases leaves no swelling.
  5. Depending upon the choice of dermal filler, the results of the facelift can last up to two years.
  6. The type of filler used, the depth to which they are introduced, the schedule of the sessions and the nature of the treatment - are all discussed and the factors are customized to fit your specific needs because each human being ages differently. Some people get facelifts to shape and sculpt a particular facial feature like the cheekbones. Facelifts are also done for sagging skin of the neck or drooping eyelids. They help tighten the loosening skin tissue layers of the jaws and chin.
  7. The fillers are not permanent and this is why they are completely safe. They can be broken down and expelled by the body naturally after a given period of time without any health risk.
  8. Restylane fillers can be used to treat dark circles, drooping eyebrows and remove bags from under your eyes.
  9. Defective structure of the lips can be corrected by dermal fillers.
  10. The advantage of a facelift using dermal fillers over a surgical treatment is that they can be altered with advancing age. Surgical solutions look fixed and artificial because they tighten the aging skin permanently. In case you have a concern or query you can always consult an expert & get answers to your questions!
4109 people found this helpful

Table of Content

About Rf Compound 450 Mg/300 Mg Tablet
When is Rf Compound 450 Mg/300 Mg Tablet prescribed?
What are the side effects of Rf Compound 450 Mg/300 Mg Tablet ?
Key highlights of Rf Compound 450 Mg/300 Mg Tablet
What are the substitutes for Rf Compound 450 Mg/300 Mg Tablet ?
What are the dosage instructions?
How does medicine works?
What are the interactions for Rf Compound 450 Mg/300 Mg Tablet ?