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Quetiapine

Prescription vs.OTC: Prescription by Doctor required
Last Updated: March 18, 2019

Quetiapine is an atypical antipsychotic drug that is used for treating certain mental conditions like schizophrenia and mania or depression that is related to bipolar disorder. The drug restores the balance of neurotransmitters in the brain. It improves your mood, appetite, concentration, sleep as well as your energy levels. Hallucinations and sudden mood swings can also be decreased with the help of this medication. There are two versions of Quetiapine, one is the immediate-release version, where it gets released in the blood stream immediately and the other is the extended-release version, where it releases gradually into the blood.

Belonging to the drug group atypical antipsychotics, Quetiapine is used for treating symptoms related to bipolar disorder, schizophrenia or depression. This medication works by restoring the neurotransmitters’ balance in the brain. It helps to decrease hallucinations in patients who are suffering from these psychotic disorders, and also improves concentration. The medicine is also effective in preventing drastic mood swings.

Quetiapine is available in tablet form and has to be taken orally. It comes in two versions, one that releases into your blood stream immediately (immediate release) and the other that gets released gradually over time in the blood stream (extended release).

Before you are prescribed Quetiapine, your doctor should be informed about your past health conditions. If you have had problems related to eye cataracts, thyroid problems, low count of white blood cells, sleep apnea, enlarged prostate, diabetes, cholesterol and high blood pressure, ensure that your doctor is informed about it. The dosage depends on your age, your present medical condition and it's severity, and how your body reacts after the first dose.

The possible side effects of Quetiapine are drowsiness, constipation, tiredness, blurred vision, increase in weight and dry mouth. In the initial days after you start taking the medicine, you may also feel light-headed or dizzy. These symptoms are generally mild in nature and disappear in a few days, but you can seek medical advice if it is bothersome.

Quetiapine may have some serious side effects too, for which you must stop taking the medication at once and consult your doctor immediately. They are:

  • Neuroleptic Malignant Syndrome, the symptoms of which are excessive sweating, high fever, severe confusion, dark urine, stiffness of the muscles and change in blood pressure, heart beat or breathing
  • Tardive dyskinesia; where you can develop uncontrolled or unusual movements, especially of your lips, mouth, face, tongue, arms and legs
  • Tremors or seizures
  • Mood changes, feeling depressed, anxious or having suicidal tendencies
  • Trouble urinating
  • Yellowing of the eyes or the skin
  • Milky discharge from breast in women, breast enlargement in both women and men
  • Low white blood cell count
  • An allergic reaction

As Quetiapine can cause dizziness and drowsiness, it is advised to avoid alcohol while you are taking this medicine, as it can worsen your condition. Ensure that you rise slowly if you are sitting or lying down to prevent falling down. Also, stay away from activities that may require your full concentration in the first few days of taking the medication.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

Quetiapine is used in the treatment of Schizophrenia. Delusions, hallucinations, reduced speaking are some of the symptoms of Schizophrenia.
Quetiapine is used in the treatment of bipolar disorder. Unusual shifts in the mood like hyperactivity and tiredness are some of the symptoms of Bipolar disorder.
Quetiapine is used in the treatment of autism. Lack of social interaction, inability to speak and repetitive movements are some of the symptoms of Autism.
Avoid if you have a known allergy to Quetiapine or any other antipsychotics.
In addition to its intended effect, Quetiapine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Aggression or anger

Major Common

Loss of balance control

Major Common

Changes in vision

Major Common

Skin rash

Major Common

Back pain

Major Less Common

Changes in pattern of speech

Major Less Common

Confusion

Major Rare

Dizziness

Major Rare

Loss of appetite

Major Rare

Constipation

Minor Common

Dry mouth

Minor Common

Weight gain

Minor Common

Body pain

Minor Less Common

Decrease in libido

Minor Less Common

How long is the duration of effect?

The effect of this medicine lasts for a duration of 9 hours in extensive metabolizers and 1 to 2 days in poor metabolizers.

What is the onset of action?

The peak effect of this medicine is observed within 1 hour of oral administration.

Are there any pregnancy warnings?

This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.

Is it habit forming?

No habit forming tendency has been reported

Are there any breast-feeding warnings?

This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available.

Are there any missed dose instructions?

Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Are there any overdose instructions?

Seek emergency medical treatment or contact the doctor in case of an overdose.

India

United States

Japan

Below is the list of medicines, which contains Quetiapine as ingredient
Sun Pharma Laboratories Ltd
Icon Lifesciences
Micro Labs Ltd
Torrent Pharmaceuticals Ltd
Abbott Healthcare Pvt. Ltd
Alkem Laboratories Ltd
Alteus Biogenics Pvt.Ltd
Sun Pharma Laboratories Ltd
Sun Pharma Laboratories Ltd
Intas Pharmaceuticals Ltd
Micro Labs Ltd
Crescent Formulations Pvt. Ltd
Abbott Healthcare Pvt. Ltd
Torrent Pharmaceuticals Ltd
Abbott Healthcare Pvt. Ltd
Glenmark Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Talent Healthcare
Intas Pharmaceuticals Ltd
Quetiapine belongs to the class atypical antipsychotics. It works by binding to the D2 and serotonin (5HT2) receptors and inhibits the release of chemical substances thus helps in reducing the symptoms
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Dementia

Major
This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

Interaction with Alcohol

Alcohol

Major
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving and operating machinery.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Clozapine

Major
Quetiapine is not recommended with clozapine due to increase risk of low blood pressure, dizziness, and irregular heart beat. Inform the doctor if you develop any undesired effects during the treatment. An alternate medicine should be considered based on the clinical condition.

Tramadol

Major
Tramadol may increase the risk of seizures when taken with Quetiapine. This interaction is more likely to happen in the elderly population, and in the patients with head injury. Inform the doctor if you are on either of the medicines. An alternate medicine should be considered based on the clinical condition.

Levodopa

Moderate
Quetiapine may reduce the effect of levodopa. If coadministration is recommended monitoring of side effects like drowsiness, low blood pressure is necessary. Avoid operating heavy machinery and driving vehicle. Dose adjustments or an alternate medicine should be considered based on the clinical condition.

Antihypertensives

Moderate
You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

Antidiabetic medicines

Moderate
The desired effect of antidiabetic agents may not be achieved when taken with Quetiapine. Regular monitoring of blood glucose levels is necessary. Inform the doctor if you develop any symptoms like excessive thirst, increased in the frequency of urination. Dose adjustments are to be made based on the clinical condition.

Ques: What is Quetiapine?

Ans: Quetiapine is an antipsychotic drug that is used for manic depression. It performs its actions by restoring the balance of neurotransmitters in the brain. This medication helps to treat various mental issues such as bipolar disorders, schizophrenia, and sudden mood changes. Quetiapine also decreases hallucinations and improves the level of energy, sleep, and appetite. It also controls nervousness, mood swings, and mental illness.

Ques: What are the uses of Quetiapine?

Ans: Quetiapine is a drug that is used for the treatment of various mental issues such as bipolar disorders, schizophrenia, and sudden mood changes. It also avoids episodes of mania, depression, and sadness. Quetiapine is not prescribed to the patients having dementia. The patient should inform the doctor about any ongoing medications and treatment before using this medication to avoid undesirable effects.

Ques: What are the Side Effects of Quetiapine?

Ans: Quetiapine is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. Here are some side effects of are high fever, excessive sweating, rigid muscles and breathing difficulty. Some other side effects are rigid muscles, increased blood pressure and heartbeat. If you experience any of the below-mentioned side effects, contact your doctor immediately. It is a list of possible side-effects which may occur due to the constituting ingredients of Quetiapine.

Ques: What are the instructions for storage and disposal Quetiapine?

Ans: Quetiapine should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using Quetiapine to avoid undesirable effects. It is important to dispose of expired and unused medications properly to avoid health problems.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Quetiapine
What are the uses of Quetiapine
What are the contraindications of Quetiapine ?
What are the side effects of Quetiapine ?
Key highlights of Quetiapine
What are the dosage instructions?
Where is the Quetiapine approved?
Medicines containing Quetiapine
How does medicine works?
What are the interactions of Quetiapine ?
Quetiapine Frequently Asked Questions (FAQs):