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Nicip Plus Tablet

Manufacturer :  Cipla Ltd
Medicine Composition :  Nimesulide, Paracetamol
Prescription vs OTC : Prescription by Doctor not required

About Nicip Plus Tablet

Nicip Plus Tablet is an anti-inflammatory pain killer which is also a non-steroidal tablet. It can be used to treat acute pain, pain related to menstrual cramps, backache, post-operative pains, osteoarthritis and fever.

As this medicine is a combination of two drugs belonging to the same class, which is NSAID (Non-steroidal anti-inflammatory drugs). This medication functions by blocking the cyclooxygenases which actually produces pain signals in our body.

This drug works by exerting pain-relieving activities. Cyclooxygenases and Prostaglandin are the reasons for the occurrence of inflammation, swelling of joints and other acute pains.

Cyclooxygenase is a type of enzyme which produces compounds known as Prostaglandin. The existence of Prostaglandin in your body creates inflammation in joints, swelling and pain. Nicip Plus is a cyclooxygenase inhibitor, so it effectively reduces these symptoms.

You should inform you doctor if you have:

  • History of ulcer or bleeding stomach
  • Kidney disease
  • Liver disease
  • High Blood pressure
  • Heart disease

If this medicine is given in high dosage, these drugs can also be used in treating inflammation in the body. But it is not good to use the drug for a prolonged period due to its harmful side effects. It is always advisable to finish the passage within 15 days.

Also Read: Trika 0.25 MG Tablet Uses

    What are the uses of Nicip Plus Tablet

    What are the contraindications of Nicip Plus Tablet ?

    What are the side effects of Nicip Plus Tablet ?

    Key highlights of Nicip Plus Tablet

    • How long is the duration of effect?

      The effect of the medicine lasts for 4-6 hours on an average. It can differ from person to person.

    • What is the onset of action?

      Nicip Plus Tablet starts working in full swing in around 15 minutes giving you quick relief.

    • Is it habit forming?

      No, the medication has no habit-forming or addictive tendencies reported till now.

    • Is It safe with alcohol?

      No, it is not at all safe to consume alcohol while on this medication as it can cause severe or irreversible side effects. You must stop the consumption of alcohol during the medication term period.

    • Are there any pregnancy warnings?

      Nicip Plus Tablet is not safe for pregnant women and special care must be given in the last trimester of pregnancy. The side effects of medicine can affect the growth of the child and hamper its development.

    • Are there any breast-feeding warnings?

      There is no conclusive evidence on whether the ingredients of medicine transfer through the breast milk or not and therefore, it is better if breastfeeding women avoid this medication or consult the doctor before taking it.

    • Is it safe to drive while on this medicine?

      If you feel drowsiness, dizziness or fatigue, you must not indulge in driving or any such activity that requires alertness and coordination. Furthermore, while on medication, you must not consume alcohol and then indulge in driving.

    • Does this affect kidney function?

      The medicine can affect kidney adversely if used for a long time. Therefore, it is important that you do not take the medication for a long time.

    • Does this affect liver function?

      Nicip Plus Tablet can cause abnormalities in liver function. It is advisable that you discuss any of the medical history related to liver to your doctor as it can aggravate the existing conditions.

    What are the substitutes for Nicip Plus Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nicip Plus Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If the Nicip Plus medicine is taken on a regular basis then you must consume the missed dose as soon as you remember it. You must not take the missed dosage if it is time for the next dose. A double dose can lead to overdose of the medication.

    • Are there any overdose instructions?

      Whenever there is a case of overdose, you must immediately seek the services of a doctor and treat you accordingly. If you witness the symptoms like sever stomach pain, nausea, seizures or low blood pressure, you must consult a doctor at the earliest.

    How does this medication work?

    Nicip Plus Tablet improves the patient's condition by blocking the production of prostaglandins thereby relieving pain and inflammation. It is is used for Acute pain, Rheumatoid arthritis, Osteoarthritis, Dysmenorrhea, etc.

      What are the interactions of Nicip Plus Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        The medication reacts with alcohol violently and can cause serious damage to your health with severe or irreversible side effects.

      • Interaction with Medicine

        Yes, it can cause some serious health issues upon interaction with certain medicines. Therefore, it is crucial that you inform your doctor about all the medication you are already taking.

        Ketoconazole, methotrexate, warfarin, amoxicillin and clavulanic acid are few of the medicines that can cause severe side effects when interacted with Nicip Plus tablet.

      • Interaction with Disease

        Nicip Plus Tablet can cause or worsen some of the serious conditions related to liver diseases. It is advisable that you do not use the medication if you have any kind of impairment in the liver.

      • Interaction with Food

        There is no sufficient information regarding the interaction between the medicine and any specific food.

      FAQs about Nicip Plus Tablet

      • Ques : What is Nicip Plus Tablet used for?

        Ans : This medication has Nimesulide and paracetamol as an active ingredient. It is a Non-Steroidal Anti-Inflammatory Drug (NSAIDs) which reduces Pain, Fever, Swelling, and redness. It is also used to treat pain caused by Osteoarthritis and Menstruation, pain due to sprains, joint, and muscles.
        Note - This medicine is not recommended to the patients below 12 years.

      • Ques : Is Nicip Plus Tablet banned?

        Ans : Nicip Plus has Nimesulide and paracetamol as active ingredients and Nimesulide has some adverse effects on the liver that is why it is banned by the government of India for common fever and paediatric use also.

      • Ques : Can Nicip Plus Tablet tablet be taken during pregnancy?

        Ans : Nicip Plus has Nimesulide and paracetamol as active ingredients and it is should not be taken during pregnancy because it is a NSAIDs(Non-Steroidal Anti-inflammatory Drug) and comes under the subclass of COX 2(Cyclooxygenase) inhibitors. This medication is used to treat conditions such as acute pain (osteoarthritis and dysmenorrhea), Inflammation, Fever and joint stiffness.

      • Ques : What is Nimesulide and Paracetamol used for?

        Ans : Nimesulide and paracetamol both are equally good in case of lowering the fever, pain and irritation and on the other hand Nimesulide appears to be at least as effective as paracetamol in terms of antipyretic and anti-inflammatory activities in children with swelling of the upper upper respiratory tract and fever.

      • Ques : Is Nicip Plus Tablet tablet a painkiller?

        Ans : Yes, Nicip is a painkiller that belongs to the group of Non Steroidal Anti Inflammatory medications.

      • Ques : Can Nicip Plus Tablet cause Allergy?

        Ans : Yes, Nicip Plus can cause allergies or skin rashes. It is suggested to consult medical practitioner before consuming this medication.

      • Ques : How long should i take Nicip Plus Tablet?

        Ans : It is advised to take for up to 15 days. If the patient exceeded this limit of consuming this medication, then it may have some adverse effects.

      • Ques : Can Nicip Plus Tablet be taken empty stomach?

        Ans : No, It is advised to consume with food to reduce the risk of Gastric issues.

      • Ques : Is Nicip Plus Tablet addictive?

        Ans : Nicip Plus Tablet is not addictive in any form. This tablet does not contain any addictive or controlled substances. However, it is always good to be safe and to stay away from an overdose.

      • Ques : Is Nicip Plus Tablet recommended for fever and headache?

        Ans : Yes, it can be used for fever and headache. But the medicine only subsides fever for some time and it doesn’t treat the cause. Also, a doctor should be consulted before consuming this medication.

      • Ques : What precautions should be followed by heart patients?

        Ans : This medication should be taken under the supervision of a doctor and meanwhile, some other medicines should be taken to minimize the risk. If any undesirable effects are experienced, then a doctor should be consulted.

      • Ques : Is Nicip Plus Tablet addictive?

        Ans : This medication is not addictive in any form. This tablet does not contain any addictive or controlled substances. However, it is recommended not to overdose on the medication.

      • Ques : Is Nicip Plus Tablet recommended for fever and headache?

        Ans : Yes, Nicip Plus Tablet can be used for fever and headache. However, the medication only subsides fever for some time and doesn’t treat the cause. Please consult your physician before consuming this medication.

      • Ques : What precautions should be followed by heart patients while taking Nicip Plus Tablet?

        Ans : Nicip Plus Tab should be taken under the supervision of a doctor only. If you experience any undesirable effects, consult your physician immediately.


      • [Internet]. 2017 [cited 28 February 2017]. Available from:

      • European Medicines Agency - Nimesulide [Internet]. 2017 [cited 28 February 2017]. Available from:

      • Nimesulide - DrugBank [Internet]. 2017 [cited 28 February 2017]. Available from:

      • nimesulide | C13H12N2O5S - PubChem [Internet]. 2017 [cited 28 February 2017]. Available from:

      • nimesulide Full Prescribing Information, Dosage & Side Effects | CIMS India [Internet]. 2017 [cited 28 February 2017]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician

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