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Overview

Nimesulide

Prescription vs OTC : Prescription by Doctor required

About Nimesulide

Nimesulide is a drug used for the management of pain and to treat fever. It is commonly prescribed to acute pain, pain related to menstrual cramps, backache, post-operative pains, osteoarthritis and fever. This drug belongs to the class of NSAID (Non-steroidal anti-inflammatory drug).

This medication functions by blocking the cyclooxygenases which actually produces pain signals in our body. Cyclooxygenases and Prostaglandin are the reasons for the occurrence of inflammation, swelling of joints and other acute pains.

Nimesulide works by exerting pain-relieving activities. Cyclooxygenase is a type of enzyme which produces compounds known as Prostaglandin. The existence of Prostaglandin in your body creates inflammation in joints, swelling and pain.

Nimesulide is a cyclooxygenase inhibitor, so it effectively reduces these symptoms. This medicine targets all the components resulting in the development of swelling such as free radicals, proteolytic enzyme, histamine, cyclooxygenases and prostaglandin.

This drug, if given in high dosage, can also be used in treating inflammation in the body. But it is not good to use the drug for a prolonged period due to its harmful side effects. It is always advisable to finish the passage within 15 days.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Nimesulide

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Nimesulide ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Nimesulide ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Nimesulide

    • How long is the duration of effect?

      On average, the effects of the medication can last for 24 hours.

    • What is the onset of action?

      The onset of the effects is immediate.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Is it habit forming?

      There are no habit forming tendencies reported with this medicine.

    • Are there any breast-feeding warnings?

      This medicine is not safe for breastfeeding women. Consult your doctor before using it.

    • Is It safe with alcohol?

      This medicine is not safe with alcohol. If you experience certain symptoms such as stomach bleeding or ulcers, then you must speak to your doctor immediately.

    • Is it safe to drive while on this medicine?

      Yes, you can drive after taking this medicine.

    • Does this affect kidney function?

      Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

    • Does this affect liver function?

      Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

    • Are there any overdose instructions?

      If you have overdosed on the pill, you must consult your doctor immediately.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Nimesulide approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Medicines containing Nimesulide

    Below is the list of medicines, which contains Nimesulide as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This drug improves the patient's condition by blocking the production of prostaglandins thereby relieving pain and inflammation. It is is used for Acute pain, Rheumatoid arthritis, Osteoarthritis, Dysmenorrhea, etc

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Nimesulide ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        The medication has interactions with certain diseases. This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver disease due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine.

      • Interaction with Medicine

        This drug interacts with corticosteroids, anti-coagulants, diuretics, angiotensin conversion enzyme inhibitors, etc.

      FAQs about Nimesulide

      • Ques : What is Nimesulide?

        Ans : It belongs to a group of drugs known as non-steroidal anti-inflammatory drugs (NSAID). This medicine performs its action by obstructing the release of specific chemicals in the brain that are responsible for pain, fever, and swelling (redness).

      • Ques : What are the instructions for storage and disposal Nimesulide?

        Ans : Store this drug in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children.

      • Ques : How long do I need to use Nimesulide before I see improvement of my conditions?

        Ans : This medication takes 1 or 2 days before you see an improvement in your health conditions.

      • Ques : What are the contraindications to Nimesulide?

        Ans : Do not use this drug if you are allergic to the stomach and intestinal disorders, alcoholism and drug addiction, etc.

      • Ques : Is Nimesulide safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

      • Ques : Will Nimesulide be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as abnormal functioning of the kidneys, abnormalities of the heart, liver damage, ruptured bowel, stomach, and intestinal bleeding, etc.

      • Ques : Is Nimesulide an antibiotic?

        Ans : No, Nimesulide is not an antibiotic. The medication is a non-steroidal anti-inflammatory drug (NSAIDs). It provides relief from pain associated with various diseases.

      • Ques : Can I take Nimesulide with paracetamol?

        Ans : Both Nimesulide and paracetamol are non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking both of them together is not recommended as it may increase the potential for gastric ulceration and bleeding. In any case, please consult your physician before you consume the two medicines together.

      • Ques : Does Nimesulide contain aspirin?

        Ans : No, the medication does not contain aspirin.

      • Ques : Is Nimesulide safe?

        Ans : Yes, the medication is completely safe to consume. However, it should be taken according to the prescribed dose and duration as advised by your physician.

      • Ques : Can I take Nimesulide for a headache?

        Ans : Yes, the medication can be taken for a headache but only when prescribed by the physician.

      • Ques : Does Nimesulide make you drowsy (feeling sleepy)?

        Ans : No, the medication does not make you feel drowsy when taken in prescribed doses. However, an overdose of Nimesulide can make you drowsy (feeling sleepy).

      • Ques : Does Nimesulide contain sulphur?

        Ans : No, the medication does not contain sulphur.

      • Ques : What does Nimesulide treat or used for?

        Ans : Nimesulide is prescribed to treat acute pain, painful osteoarthritis (degeneration of joints) and primary dysmenorrhea (painful menstruation) in adolescents and adults above 12 years old.

      • Ques : Can I take Nimesulide with ibuprofen?

        Ans : Yes, Nimesulide can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. Please consult your doctor before taking the two medicines together.

      • Ques : Can I take Nimesulide with aspirin?

        Ans : Yes, the medication can be taken along with aspirin. No drug-drug interactions have been clinically observed between the two. However, please consult your physician before taking them together.

      • Ques : Is Nimesulide safe?

        Ans : Yes, Nimesulide is completely safe when taken for prescribed duration in prescribed doses as advised by the physician.

      • Ques : Is Nimesulide banned?

        Ans : No, the medication is not banned in India.

      • Ques : Is Nimesulide safe during breastfeeding?

        Ans : It is not known if the medication is secreted in milk. So, any medicines containing Nimesulide are not to be used during breastfeeding.

      • Ques : Is Nimesulide safe in asthma?

        Ans : The medication is reported to be safe in patients with asthma. However, it is recommended that you share your disease history with the doctor in case you have asthma.

      References

      • Nimesulide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nimesulide

      • Nimesulide - DrugBank [Internet]. Drugbank.ca. 2021 [cited 3 December 2021]. Available from:

        https://go.drugbank.com/drugs/DB04743

      • Nimesulide - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2021 [cited 03 December 2021]. Available from:

        https://pubchem.ncbi.nlm.nih.gov/compound/4495

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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