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Duoflam 400Mg/500Mg Tablet

Manufacturer: Maneesh Pharmaceuticals Ltd
Medicine composition: Ibuprofen, Paracetamol
Prescription vs.OTC: Prescription by Doctor required

Duoflam 400Mg/500Mg Tablet treats inflammations as well as pain. It acts as a non-steroidal anti-inflammatory drug (NSAID) that controls hormones in the body which cause pain and inflammation. It thus offers relief from several problems like toothache, headache, arthritis, pain in the back, other types of small injuries and menstrual cramps.

The drug is suitable for adults as well as children who are 6 months and above.

Ensure that you do not take Duoflam 400Mg/500Mg Tablet if-

  • You have heart disease and are at a risk of suffering from a stroke or heart attack. Even those who do not have heart problems are likely to suffer a stroke or a heart attack because of prolonged use of Duoflam 400Mg/500Mg Tablet.
  • You have recently had a bypass operation.
  • You are allergic to any substance that is present in Duoflam 400Mg/500Mg Tablet.

If you have health problems like asthma, fluid retention, kidney issues, frequent development of ulcers and bleeding, ask you medical practitioner if you can take Duoflam 400Mg/500Mg Tablet. The drug should not be taken during the last trimester of pregnancy as it has been found that it can harm the fetus. Research has not revealed if the drug is harmful for infants who are still breast feeding. In this case it is best that you take your doctor’s advice.

You will experience a few side effects when you take this medication. In case of Duoflam 400Mg/500Mg Tablet some minor side effects that may occur are anemia, vomiting, hypertension, hemorrhage, low hemoglobin levels and eosinophilia. These side effects are quite common and will go away in some time. Get in touch with your health care provider as soon as possible if you develop some of these more serious side effects like pain in the stomach, indigestion, problems with breathing, weight gain, itchy skin, feeling excessively tired and weak, problems with urinations and bowel movements, development of acid in the stomach etc.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Duoflam 400Mg/500Mg Tablet is used to relieve excessive pain and cramps during menstruation.
Duoflam 400Mg/500Mg Tablet is used to treat symptoms like tender and painful joints associated with Osteoarthritis.
Duoflam 400Mg/500Mg Tablet is used to treat symptoms like swelling, pain, and stiffness of joints associated with Rheumatoid Arthritis.
Fever and Pain
Duoflam 400Mg/500Mg Tablet is used to treat headache, back pain, and fever.
Not recommended in patients with known allergy to Duoflam 400Mg/500Mg Tablet or non-steroidal anti-inflammatory (NSAID) drugs
Not recommended in patients with known conditions like asthma, rhinitis, and urticaria.
Coronary Artery Bypass Surgery (CABG)
Not recommended in patients with recent heart surgery.
Not recommended in patients with peptic ulcer disease or any gastrointestinal bleeding disorders.
In addition to its intended effect, Duoflam 400Mg/500Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Acid or sour stomach Major Common
Heartburn Major Common
Nausea and Vomiting Major Common
Abdominal discomfort Major Less Common
Constipation Major Rare
Decreased urine output Major Rare
Yellow colored eyes or skin Major Rare
Skin rash Major Rare
Ringing or buzzing in the ears Minor Common
Nervousness Minor Common
Loss of appetite Minor Rare
Running Nose Minor Rare
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 4 to 6 hours.
What is the onset of action?
The effect of this medicine can be observed in 30 to 60 minutes.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is known to excreted through breast milk in small amounts. It is recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Duoflam 400Mg/500Mg Tablet , and hence can be used as its substitute.
Indoco Remedies Ltd
Concept Pharmaceuticals Ltd
Lincoln Pharmaceuticals Ltd
Aristo Pharmaceuticals Pvt Ltd
Sun Pharmaceutical Industries Ltd
Wings Biotech Ltd
Psychotropics India Ltd
Iatros Pharmaceuticals Pvt Ltd
Micro Labs Ltd
Natco Pharma Ltd
Adonis Laboratories Pvt Ltd
Allentis Pharmaceuticals Pvt Ltd
Shreya Life Sciences Pvt Ltd
Psychotropics India Ltd
Comed Chemicals Ltd
Adcock Ingram Healthcare Pvt Ltd
NuLife Pharmaceuticals
Alkem Laboratories Ltd
Group Pharmaceuticals Ltd
Swiss Pharma Pvt Ltd
Alkem Laboratories Ltd
Ranbaxy Laboratories Ltd
Sun Pharmaceutical Industries Ltd
Vintech Formulations
Nestor Pharmaceuticals
Leben Laboratories Pvt Ltd
Fytokem Formulations
Syncom Formulations I Limited
Missed Dose instructions
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of overdose.
United States
Duoflam 400Mg/500Mg Tablet is a nonsteroidal anti-inflammatory drug that works by inhibiting the enzymes cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Asthma Major
Duoflam 400Mg/500Mg Tablet should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.
Fluid Retention and edema Major
Duoflam 400Mg/500Mg Tablet should be taken only after consulting a doctor. Monitoring of blood pressure and heart conditions is necessary on a regular level during the course of therapy.
Skin rash Major
Duoflam 400Mg/500Mg Tablet can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. This condition requires immediate medical intervention.
Interaction with Alcohol
Alcohol Moderate
This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.
Interaction with Lab Test
Information not available.
Interaction with Food
Information not available.
Interaction with Medicine
Methotrexate Major
Duoflam 400Mg/500Mg Tablet may increase the blood levels of methotrexate and can cause liver injury, breathing problem, and bleeding. Inform the doctor if you are receiving pain killers. The dose should be adjusted based on the clinical condition. Close monitoring of kidney function and blood cell count is necessary.
Corticosteroids Moderate
Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.
Aspirin Major
Duoflam 400Mg/500Mg Tablet may reduce the effect of aspirin and increases the risk of bleeding. Any symptoms like gastrointestinal bleeding, abdominal pain, blood in stools should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.
Antihypertensives Moderate
If you are taking antihypertensives like furosemide and ramipril with Duoflam 400Mg/500Mg Tablet, then you are at increased risk of kidney damage. This interaction is more likely to happen in the elderly population. Regular monitoring of kidney function is necessary. The dose should be adjusted based on the clinical condition.
What are you using Duoflam 400Mg/500Mg Tablet for?
Fever and Pain
How much was the improvement?
How long did it take before seeing improvement?
Within 2 hours
How frequently did you take this medicine?
Thrice a day
Not taking on daily level
Once a day
How did you take this medicine?
With Food
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am 28 years old female and am suffering from Thyroid (normal level of thyroid should be between 0.25 mg-5.50mg, but mine is 8.50mg. Can you please me the foods to be avoided and foods to be taken. I mean the diet.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Dharwad
you are very right about normal range of tsh levels. At 8.5 milli units/ml, with normal t4, the condition is classified as sub- clinical hypothyroidism. This normally is not treated with any drugs. Treatment is advised only once the levels cross 10 milli units or there are troublesome symptoms with lower tsh levels. As regards food intake you have to have a balanced diet, but avoid certain foods like - soy beans, soy containing products, cabbage, cauliflower, broccoli, peanuts, radish, mustard and coffee. Consume good deal of green leafy vegetables, salads and fruits. Use whole grain flour for making chapati or roti. Do not use refined flour like maida. If you are taking non- vegetarian diet then take lean meat, skinned chicken and fish. Exercise regularly, that is important. Further, if one is desirous of having conception, then before conception tsh levels have to be brought down to around 2 mill units/ml. Keep that in mind. Thanks for the question.
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Newcold-ML 5mg+10mg this tablet is used for which purpose as I had asked to pharmacist for allergy of Chinese food because I was facing problem of allergy. However no effect after taking this tablet. Please suggest.

AUTLS, CCEDM, MD - Internal Medicine, MBBS
General Physician, Faridabad
if u r allergic to some food etc.. the remedy is...simply avoid that food u can take lezyncet for some time
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I am a 57 years old and suffering from diabetes, at present taking glimperide - 2+2, zita-met 50mg/500mg - 1+1 and volibo-m. 03-1+1+1. Please advice me if there is any alternative medicine because these are very costly. Regards

General Physician, Nashik
You need a large amount of medicines. Kindly attach your recent bsl reports and revert back to me for further assistance.
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Hi, I am 29 years old with diabetes mellitus type 2. Am taking galvus met 50mg/1000mg daily twice. At night am taking 1 actos 30mg. Still my fasting sugar level is 220. I am not using any sugar food and rice. Kindly advice. My hba1c is 12.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Zirakpur
Hi, I am 29 years old with diabetes mellitus type 2. Am taking galvus met 50mg/1000mg daily twice. At night am taking...
It's cause of concern that your insulin is not acting to neutralize the sugar while you are taking good medicines prescribed by your experience doctor. This is non response of drugs. It's not fault in treatment by your doctor. I would suggest the support of ayurveda medicine as support to your current medicine. Both won't counteract with each other. Observing the response of this integrative approach, further directions would be decided. If you agree, I would mention the first phase of safe, side effect less, easy to take and economic medicines which will prevent complications also.
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Table of Content

About Duoflam 400Mg/500Mg Tablet
When is Duoflam 400Mg/500Mg Tablet prescribed?
What are the contraindications of Duoflam 400Mg/500Mg Tablet ?
What are the side effects of Duoflam 400Mg/500Mg Tablet ?
Key highlights of Duoflam 400Mg/500Mg Tablet
What are the substitutes for Duoflam 400Mg/500Mg Tablet ?
What are the dosage instructions?
Where is the Duoflam 400Mg/500Mg Tablet approved?
How does medicine works?
What are the interactions for Duoflam 400Mg/500Mg Tablet ?