Debura 300 Mg/500 Mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). The drug is administered mainly for the pain-relieving properties of this medicine, especially in cases of severe arthritis, muscular strains, sprains and other painful injuries. The medicine may also be used to provide relief from menstrual pain, abdominal cramps and even dental aches. It may be taken orally along with food or as directed by the doctor.
Debura 300 Mg/500 Mg Tablet, like ibuprofen and other NSAIDs, works by preventing the oxidation of arachidonic acid by inhibiting the enzyme cyclo-oxygenase (COX). This results in decrease in the production of prostaglandins which are responsible for inflammation and pain and thus leads to its analgesic and anti-inflammatory properties.
This medicine should not be taken if you are suffering from kidney or liver problems, heart disease, peptic ulcers, gastrointestinal bleeding, Crohn's disease or during pregnancy and breastfeeding unless absolutely necessary. Caution is advised for its use in elderly people, people with hypertension, diabetes and high blood cholesterol and in people who have had a stroke in the past.
The most common side effects of this medicine are related to irritations of the stomach including indigestion, acidity or heartburn. Thus it is recommended to be taken with food to avoid such discomfort. It might also cause dizziness, weakness or drowsiness and hence should not be taken before driving a car or operating machinery.
Paracetamol is one of the most commonly consumed medicine to deal with minor pain, body ache, headache, fever etc. It can also be used for getting temporary relief from arthritis pain. This is readily available over the counter and can be obtained without a prescription. The dosage is available in the form of syrup, powder, solution, tablet, suspension, suppository etc.
Considerations to make before consuming paracetamol:
The risk of the medicine must be considered before consuming it. The health care professional should be reported for any allergy related problems. For a person facing allergy, one should carefully read the label before consuming it. Interaction of 2 paracetamol can prove to be fatal sometimes. The dosage, therefore, of these medicines should be consulted with the doctor. This being said, there are certain medicines which act best when they are consumed together. The outcome of the effect is based on the disease one is facing. The effectivity of this medicine can get influenced if the patient has a history of abusing alcohol, suffered from liver and kidney diseases in the past etc.
Proper use of paracetamol:
Paracetamol should be consumed with care. Prolonged consumption can damage the liver. The maximum dosage of this medicine should not exceed 3k milligrams in a day. This can be consumed before or after the consumption of food. Paracetamol in the form of syrup should be shaken well before use. There should be a minimum time span of 4-6 hours between two dosages of paracetamol. In the case of a missed dosage, the medicine should be taken as early as possible. It does not prove to be fatal in case a dosage is missed. Finally, it should be ensured that paracetamol is stored at room temperature and freezing is avoided.
It is of utmost importance to check the progress of the patient in case one is consuming paracetamol. During the process of consuming paracetamol, symptoms such as dark urine, stomach ache, nausea, weakness etc should be immediately reported to the stomach. For patients suffering from diabetes, any drastic change in the blood sugar level due to the consumption of paracetamol should be immediately reported to the doctor.
Certain rare side-effects of paracetamol include lower back pain, bruising, fever, cloudy urine, tarry stools, yellowish skin, bruising, skin rash, itching etc. Some common symptoms of overdosage of paracetamol include increased sweating, tenderness, swelling and pain in the lower abdomen area, vomiting and nausea, diarrhea, appetite loss, increased thrust etc. If any of these symptoms are faced during the consumption of paracetamol are reported, a healthcare professional should be immediately consulted to avoid any further complication. Frequent usage should also be avoided. If you wish to discuss about any specific problem, you can consult a General Physician.
As per a study conducted by the Copenhagen University Hospital, it was revealed that consuming paracetamol during pregnancy can be detrimental for your baby, as it can weaken the development of the reproductive system of female offspring. The research was published in Endocrine Connections journal.
Although, paracetamol is an over-the-counter treatment for pain relief that is commonly taken by pregnant women worldwide. The study was conducted on three individual rodents and the results indicated that the rodents, who were given paracetamol during pregnancy at doses equivalent to those that of a pregnant woman may take for pain relief, produced female offspring with fewer eggs.
Further, Dr. Kristensen said, "Although this may not be a severe impairment to fertility, it is still of real concern since data from three different labs all independently found that paracetamol may disrupt female reproductive development in this way, which indicates further investigation is needed to establish how this affects human fertility."