Cyra-Ls Tablet

Manufacturer: Systopic Laboratories Pvt Ltd
Medicine composition: Levosulpiride, Rabeprazole
Prescription vs.OTC: Prescription by Doctor not required

Cyra LS Tablet is a combination medication, primarily used for treating ulcerative GERD. It is also prescribed for erosive healing, maintenance of ulcerative GERD, duodenal ulcers, irritable bowel syndrome and chronic gastritis. Recently, it has also come to be used in the treatment of hypersecretory conditions that include Zollinger-Ellison syndrome.

On using Cyra-Ls Tablet the associated side effects that you may suffer from are disorientation, delirium, the elevation of thyroid-stimulating hormone (TSH), rhabdomyolysis, bullous, erythema multiforme, drug-induced diarrhoea, twitching, tremor, weight gain or akathisia.

In certain severe cases, you may experience jaundice, interstitial pneumonia, tardive dyskinesia, gynecomastia (a disorder of the endocrine system where there is an enlargement of the male breast size). In the latter case it will be necessary for you to seek medical attention.

Before using Cyra LS Tablet it is advised that you consult your doctor and tell him/her if you had/have or are:

  • Pregnant, or are planning to become pregnant.
  • Nursing a baby
  • Taking any prescriptive or over the counter drugs, herbals medications or dietary supplements.
  • A recent surgery or are scheduled for one in the near future.
  • Pheochromocytoma or gastrointestinal perforation.
  • A history of cancer-related disease.
  • A history of epilepsy or any other kind of seizures.
  • Allergic to any medicine, food or substance.

The dosage of this medication will be as prescribed by your doctor as per the severity of your condition, your age, gender and overall medical history. But commonly a dose of 25 mg of this medicine is prescribed which needs to be taken three times in a day. Results may start to show within an hour or two of using. In case of drug overdose notify your physician right away.

Also Read: Biopreg F Tablet Uses and Side Effects

Cyra LS Tablet is useful against the following conditions:

  • Gastroesophageal Reflux Disease

    This medicine is used for the treatment of gastroesophagal reflux disease marked by increased irritation of the stomach caused by bile and acid.
  • Irritable Bowel Syndrome (Ibs)

    Cyra LS Tablet is used for the treatment of irritable bowel syndrome marked by persistent stomach pain, flatulence, diarrhea, or constipation.
  • Duodenal Ulcer

    This medicine is used for the treatment of duodenal ulcer marked by severe abdominal pain, heartburn, indigestion, bloating, belching, nausea or vomiting.

Here are some of the possible side effects of Cyra LS Tablet

  • How long is the duration of effect?

    The effect of Cyra LS Tablet lasts for an average duration of 5-8 hours upon oral administration.
  • What is the onset of action?

    The effect of this medicine can be observed within 1-2 hours of oral administration.
  • Are there any pregnancy warnings?

    Use of Cyra LS Tab during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.
  • Is it safe to drive while on this medicine?

    This medicine affects the consciousness of the patient, thus driving must be avoided while taking Cyra-Ls Tablet.
  • Does this affect kidney function?

    Only limited information is available regarding its use in patients with kidney disease. Kindly consult your doctor before taking it.
  • Does this affect liver function?

    Caution must be taken in patients with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking Cyra-Ls Tablet.

Below is the list of medicines, which have the same composition, strength and form as Cyra-Ls Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
  • Are there any overdose instructions?

    Contact a doctor if an overdose with this medication is suspected. Symptoms of an overdose may include excessive drowsiness, fall in blood pressure, agitation, coma, etc.

Cyra LS Tablet is a combination of Levosulpiride and Rabeprazole. These two belongs to neuroleptic and PPI class respectively. Thus this medicine works via the dual mechanism.

Firstly, it works by selectively binding to dopamine receptors in the brain and the periphery. This action results in an increased tone of muscles in the gastrointestinal tract. Secondly, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.
  • Interaction with Lab Test

    Prolactin test

    Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine can interfere with the test and yield false positive results.
  • Interaction with Medicine


    Report the use of diltiazem or any other medicine taking for managing high blood pressure to the doctor. These medicines should be used with caution as the risk of adverse effects are increasingly high. Your doctor may determine the best course of treatment after assessing the conditions.


    Report the use of either of the Cyra LS medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.


    Report the use of either of the medicine to the doctor. You may require a dose adjustment and frequent clinical monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.


    Report the use of any narcotic pain-killer medicine to the doctor. These medicines should be used with extreme caution as the risk of adverse effects are significantly high. Your doctor may decide the best course of treatment after assessing the conditions.

    Aluminium Hydroxide/Magnesium Hydroxide

    Report the use of any aluminum or magnesium containing antacids to the doctor before receiving this medicine. You may need a dose adjustment and frequent clinical monitoring to safely use these medicines together.


    Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring while using these medicines together. Do not stop the use of any medicine without consulting your doctor.


    Concomitant use of this medication with warfarin causes increase in INR and prothombin time. This leads to abnormal bleeding and even death.


    If concomitantly administered, this medication inhibits the metabolism of cyclosporine and creates its concentration to be over 50 times higher than its normal Cmax.

    Other medications

    Bioavailability of this medication is reduced in presence of aluminium- and magnesium-containing antacids and with sucralfate. Its action on GI motility could also be antagonized by concomitant use of narcotics, anticholinergic agents and analgesics.
  • Interaction with Food

    Information not available.
  • Interaction with Disease

    Heart Diseases

    This medicine should be used with caution in patients suffering from a disease of the heart and blood vessels. You may require an adjusted dose and safety monitoring to safely use this medicine.

    Gastrointestinal Bleeding

    This medicine should be used with extreme caution in patients suffering from perforation and bleeding of the stomach and the intestine. Report any instance of fever with chills, nausea, vomiting, presence of blood in stool to the doctor.

    Prolactin Imbalance

    This medicine should not be used in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.

    Neuroleptic Malignant Syndrome (Nms)

    Use of this medicine is not recommended if the patient suffers from Neuroleptic malignant syndrome. Introduction or reintroduction of this medicine should be done with caution in patients having a known history of this syndrome.


    This medicine should be used with caution if you have asthma. Report any instances of difficulty in breathing, wheezing, chest pain etc to the doctor immediately.

Ques: What is Cyra-Ls Tablet?

Ans: This medicine is a combination of levosulpiride and rabeprazole. It is primarily used for the treatment of Gastroesophageal reflux disease and irritable bowel syndrome.

Ques: What are the uses of Cyra-Ls Tablet?

Ans: It is prescribed for treating the following-

  • Healing of erosive or ulcerative gastro-oesophageal reflux disease (GERD)
  • Maintenance of healing of erosive or ulcerative GERD
  • Healing of duodenal ulcers
  • Treatment of pathological hypersecretory conditions, including Zollinger- Ellison syndrome
  • Irritable bowel syndrome
  • Chronic gastritis

Ques: What are the Side Effects of Cyra-Ls Tablet?

Ans: Cyra LS Tablet has many common side effects such as Nausea, Stomach pain, Diarrhea, Flatulence, Constipation, Headache, Dizziness, Weakness, Sleepiness, Flu-like symptoms. In case of patients having any of the side effects or issues like allergic reactions or skin rashes. It is advised to stop the consumption of this medicine and contact to doctor as soon as possible.

Ques: What are the instructions for storage and disposal Cyra-Ls Tablet?

Ans: Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

Ques: How long do I need to use Cyra-Ls Tablet before I see improvement of my conditions?

Ans: Cyra LS Tablet which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

Ques: What are the contraindications to Cyra-Ls Tablet?

Ans: Contraindication to Cyra-Ls. In addition, this medication should not be used if you have the following conditions such as Hypersensitivity, Malignant mastopathy, Mammary dysplasia, Manic states, Pheochromocytoma, Pregnant, etc.

Ques: Is Cyra-Ls Tablet safe to use when pregnant?

Ans: Cyra LS Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Ques: Will Cyra-Ls Tablet be more effective if taken in more than the recommended dose?

Ans: No, taking higher than the recommended dose of Cyra LS Tablet can lead to increased chances of side effects such as Indigestion, Changes in sexual desire, Diarrhea, Rash, Asthenia, Joint pain, Nausea, Fracture of the hip, etc.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MD-Pharmacology, MBBS
Table of Content
About Cyra-Ls Tablet
What are the uses of Cyra-Ls Tablet
What are the contraindications of Cyra-Ls Tablet ?
What are the side effects of Cyra-Ls Tablet ?
Key highlights of Cyra-Ls Tablet
What are the substitutes for Cyra-Ls Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Cyra-Ls Tablet ?
FAQs about Cyra-Ls Tablet