Cofrest Dm Syrup

Cofrest Dm Syrup is used to gain temporary relief from stuffy nose, sinus, and ear symptoms caused by the allergies, common cold, flu, or other breathing illnesses such as sinusitis and bronchitis. This medication works by decreasing swelling in the nose and ears which makes breathing easier and lessens any discomfort.

This medicine is also used for the treatment of Treatment of hypotension, vascular failure in shock; as a vasoconstrictor in regional analgesia; symptomatic relief of nasal and nasopharyngeal mucosal congestion; as a mydriatic in ophthalmic procedures and treatment of wide-angle glaucoma; and supraventricular tachycardia.

Mild upset stomach, lightheadedness, seizures, mood changes, trouble sleeping, dizziness, shaking, headache, nervousness or fast and irregular heartbeat may occur as side effects to this medicine. It may also reduce blood flow to hands or feet, causing them to feel cold. Smoking may worsen this effect. So you are advised to dress warmly and avoid tobacco use.

To ensure complete safety, before starting the medicine tell your doctor if you suffer from blood vessel problems, diabetes, overactive thyroid, high blood pressure, mood disorders, glaucoma, heart disease, seizure disorder, difficulty sleeping or trouble urinating. This medication is recommended for use in younger children.

The dosage is based on your age. Without your doctor’s approval, do not increase your dose or frequency of this medication. Improper use of this drug can cause you serious harm.

Do not use for more than 5 days in a row. Clear nose as much as possible before use. Tilt head back and instill recommended dose of drops or spray. Do not blow nose for 5-10 minutes. You may experience transient stinging or burning.

The medicine is useful against the following conditions:

• Dry Cough

• Hypotension

• Glaucoma

• Hypersensitivity

• Hypertension

The medication is known to cause fewer side effects like:

• Headache

• Anxiety

• Weakness

• Dizziness

• Tremor

• Metabolic Acidosis

• Is It safe with alcohol?

  This medicine may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  This medicine may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Consult prescriber if breast-feeding.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  Caution to be advised in patients with severe impaired renal function.
  contraindicated in patients with moderate to severe renal impairment

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

• Are there any missed dose instructions?

  If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

The active constituent of this medication is an alpha-1 adrenergic receptor agonist belonging to the phenethylamine class, which acts as a nasal decongestant. It acts by reducing the ear and nose blood vessels swelling, thus provides relief from the discomfort.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Medicine

  • Beta-blockers (nonselective ones) may increase hypertensive effect; avoid concurrent use.
  • Cocaine may cause malignant arrhythmias; avoid concurrent use.
  • Guanethidine can increase the pressor response; be aware of the patient's drug regimen.
  • Methyldopa can increase the pressor response; be aware of patient's drug regimen.
  • Phenytoin administration during a dopamine infusion may result in hypotension and possibly cardiac arrest; use cautiously.
  • Reserpine increases the pressor response; be aware of patient's drug regimen.
  • TCAs increase the pressor response; be aware of patient's drug regimen.
  • MAO inhibitors potentiate hypertension and hypertensive crisis; avoid concurrent use.

• Interaction with Disease

  Use with caution in the elderly, patients with hyperthyroidism, bradycardia, partial heart block, myocardial disease, or severe CAD. Not a substitute for volume replacement. Avoid hypertension; monitor blood pressure closely and adjust infusion rate. Infuse into a large vein if possible. Watch I.V. site closely. Avoid extravasation. The elderly can be more sensitive to side effects from the nasal decongestant form. Rebound congestion can occur when the drug is discontinued after chronic use.