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Overview

Chlorpheniramine

Prescription vs OTC : Prescription by Doctor required

About Chlorpheniramine

Chlorpheniramine is primarily prescribed to treat perennial and seasonal allergic rhinitis and other allergic symptoms including urticaria. Chlorpheniramine is an antihistamine that works by blocking the action of histamine in the body.

It is used for relieving symptoms of sinus pressure, sinus congestion, runny nose, itching of the throat and nose, watery eyes, and sneezing due to upper respiratory infections, hay fever, and allergies.

Some adverse effects of this drug include confusion, anxiety, restlessness, blurred vision, dry mouth, decreased coordination, and irritability. Before using this medication you should notify your doctor if you have or are:

  • Allergic to this drug
  • Taking or have taken sodium oxybate, furazolidone or a monoamine oxidase inhibitor within the last 14 days
  • Breathing problems, glaucoma, heart problems, liver disease, high blood pressure, etc

You can take this drug in the form of a tablet, capsule, or liquid form by mouth with or without food. This medicine is usually recommended only for a short time until your symptoms are cleared. Do not take it for longer than 7 days in a row.

May cause drowsiness; swallow whole, do not crush or chew sustained-release product; avoid alcohol, may impair coordination and judgment. Chronic use of antihistamines will inhibit salivary flow, particularly in elderly patients; this may contribute to periodontal disease and oral discomfort.

Stability: Incompatible when mixed in the same syringe with calcium chloride, kanamycin, norepinephrine, pentobarbital.

Chlorpheniramine is contraindicated in patients with Hypersensitivity to chlorpheniramine maleate or any component; narrow-angle glaucoma; bladder neck obstruction; symptomatic prostate hypertrophy; during acute asthmatic attacks; stenosing peptic ulcer; pyloroduodenal obstruction. Avoid use in premature and term newborns due to possible association with SIDS.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the uses of Chlorpheniramine

    • Seasonal Allergic Rhinitis

    • Urticaria

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the contraindications of Chlorpheniramine ?

    • Hypersensitivity

    • Narrow Angle Glaucoma

    • Peptic Ulcer

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the side effects of Chlorpheniramine ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Key highlights of Chlorpheniramine

    • Is It safe with alcohol?

      This drug may cause excessive drowsiness and calmness with alcohol.

    • Are there any pregnancy warnings?

      This drug is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      Contraindicated in patients with moderate to severe renal impairment. Caution to be advised in patients with severely impaired renal function.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • How long is the duration of effect?

      The effect of this medicine will remain active for about 20 - 24 hours.

    • What is the onset of action?

      The effect of this medicine will be initiated within 2 hours after its administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Medicines containing Chlorpheniramine

    Below is the list of medicines, which contains Chlorpheniramine as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    How does this medication work?

    This medication falls under the category of a first-generation antihistamine, which is used to prevent allergic symptoms from conditions such as urticaria and rhinitis. It binds to the histamine H1 receptor, which prevents the action from endogenous histamine.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

      What are the interactions of Chlorpheniramine ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

        CYP2D6 enzyme substrate.
      • Interaction with Disease

        Avoid use in premature and term newborns due to possible association with SIDS.. Avoid using Chlorpheniramine in patients suffering form narrow-angle glaucoma; bladder neck obstruction; symptomatic prostate hypertrophy; during acute asthmatic attacks; stenosing peptic ulcer; pyloroduodenal obstruction.
      • Interaction with Food

        May be taken with food or water.

      FAQs about Chlorpheniramine

      • Ques : What is Chlorpheniramine?

        Ans : This drug performs its action by obstructing the release H1 receptor (chemical messengers) in the body. It is used to avoid hay fever, allergic reactions and urticaria, nasal congestion and common cold symptoms.

      • Ques : What are the uses of Chlorpheniramine?

        Ans : It is used for the treatment and prevention of conditions and symptoms of diseases like Hay fever, allergic reactions, and urticaria.

      • Ques : What are the Side Effects of Chlorpheniramine?

        Ans : These side effects include dry mouth, aplastic anemia, jaundice, and blurred vision. Apart from these, using It may further lead to drowsiness, sleepiness, and double vision.

      • Ques : What are the instructions for storage and disposal Chlorpheniramine?

        Ans : It should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Chlorpheniramine. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : Should I use Chlorpheniramine empty stomach, before food or after food?

        Ans : The consumption of this medication is done orally. If you take this medication with the food, the reactions that took place in the body carry outs in a much effective manner. Your stomach might get upset if you take this medication on an empty stomach.

      • Ques : How long do I need to use Chlorpheniramine before I see improvement of my conditions?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 3 months, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action.

      • Ques : Is there any food or drink I need to avoid?

        Ans : There is no specific food product to avoid, under usage of this medication. It will be beneficial to keep your diet healthy and to ignore street food in order to avoid any kind of harmful bacterial intake. It is also advised to stay away from drinking and smoking to uplift your health.

      • Ques : Will Chlorpheniramine be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses. Taking over-dosage of this medication may trigger side effects. If the severity of the condition is not reducing with the recommended dosage of this drug, then the doctor should be consulted for re-examining your condition.

      References

      • Chlorphenamine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 23 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/chlorpheniramine

      • CHLORPHENIRAMINE MALEATE 4MG tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 24 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91d2ec38-7ea2-2b3a-e053-2a95a90af3fd

      • CHLORPHENIRAMINE MALEATE 4MG tablet, coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 24 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d974959-25fc-4707-9b72-9afbf47b76f1

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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