Prescription vs OTC: Prescription by Doctor required

Chlorzoxazone is used for symptomatic treatment of muscle spasm and pain associated with acute musculoskeletal conditions. Take exactly as directed, with food. Do not increase dose or discontinue without consulting prescriber.

Chlorzoxazone act as a muscle relaxer. It works by blocking pain sensations or nerve impulses that are sent to the brain. Chlorzoxazone when used together with rest and physical therapy can treat skeletal muscle conditions such as injury or pain.

Avoid using this medicine if you are allergic to it or if you are taking sodium oxybate. Inform your doctor if you are pregnant, planning to become pregnant, or are breast-feeding or if you have have liver problems or a blood disease called porphyria.

Stop using this medicine and consult your doctor if you experience any serious side effects including black, bloody, or tarry stools, nausea, itching, fainting, upper stomach pain, dark urine, loss of appetite and clay-coloured stools.

Chlorzoxazone is to be taken by mouth with or without food. Taking it with food reduces the risk of stomach upset. Do not take in this medicine in larger or smaller amounts or for longer than recommended. Follow your doctor’s prescription carefully to ensure complete safety.

Do not use alcohol, prescriptive or OTC antidepressants, sedatives, or pain medications without consulting prescriber. May turn urine orange or red (normal). Report excessive drowsiness or mental agitation; palpitations, rapid heartbeat, or chest pain; skin rash or swelling of mouth or face; persistent diarrhoea or constipation; or unusual weakness or bleeding.

Symptoms of overdose include nausea, vomiting, diarrhoea, drowsiness, dizziness, headache, absent tendon reflexes, hypotension. Treatment is supportive following attempts to enhance drug elimination. Hypotension should be treated with I.V. fluids and/or Trendelenburg positioning.

Dialysis and hemoperfusion and osmotic diuresis have all been useful in reducing serum drug concentrations; the patient should be observed for possible relapses due to incomplete gastric emptying.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

The most common use of this medication is:

  • Hypersensitivity

  • Impaired Liver Function

This medicine causes side effects such as:

  • Is It safe with alcohol?

    Chlorzoxazone may cause excessive drowsiness and calmness with alcohol. Taking diclofenac with alcohol can increase your risk of stomach bleeding.
  • Are there any pregnancy warnings?

    Chlorzoxazone is unsafe to use during pregnancy.
    There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Unknown. Human and animal studies are not available. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Patients should not drive or operate machinery if they get affected symptoms like dizziness, drowsiness, fatigue, visual disturbances.
  • Does this affect kidney function?

    This medicine should be used with caution in patients with underlying kidney disease. Please Consult your doctor.
  • Does this affect liver function?

    Use of this medicine should be avoided in patients with underlying liver disease.
  • What is the onset of action?

    The effect of this drug is initiated within 1 hour after its administration.
  • How long is the duration of effect?

    The drug will remain active for about 6 - 12 hours.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Below is the list of medicines, which contains Chlorzoxazone as ingredient

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This medication is used to treat muscle spasms and also the pain caused by the same. The drug belongs to the muscle relaxant category, but the no exact mechanism of action has been determined for the medication as of yet, but the drug suppresses the central nervous system to produce the desired effects.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Additive CNS effects, avoid use.
  • Interaction with Medicine

    CYP2E1 enzyme substrate.

Ques: What is Chlorzoxazone?

Ans: Chlorzoxazone acts as a muscle relaxer.

Ques: What are the uses of the Chlorzoxazone?

Ans: It works by blocking pain sensations or nerve impulses that are sent to the brain.

Ques: How long do I need to use Chlorzoxazone before I see improvement in my condition?

Ans: This medication is to be taken till the time you see an improvement in your health conditions.

Ques: At what frequency do I need to use Chlorzoxazone?

Ans: This medication should be taken in the dosage as prescribed by the doctor.

Ques: Should I use Chlorzoxazone empty stomach, before food or after food?

Ans: This medication should be taken after food in a prescribed dosage.

Ques: What are the instructions for the storage and disposal of Chlorzoxazone?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Ques: How long does Chlorzoxazone take to work?

Ans: Usually, Chlorzoxazone starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Ques: What if I don't get better after using Chlorzoxazone?

Ans: Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Ques: Is Chlorzoxazone a habit forming medicine?

Ans: No addiction issues have been reported yet.

Ques: Does Chlorzoxazone have aspirin or codeine in it?

Ans: No. It does not contain aspirin or codeine.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Chlorzoxazone
What are the uses of Chlorzoxazone
What are the contraindications of Chlorzoxazone ?
What are the side effects of Chlorzoxazone ?
Key highlights of Chlorzoxazone
What are the dosage instructions?
Medicines containing Chlorzoxazone
How does this medication work?
What are the interactions of Chlorzoxazone ?
FAQs about Chlorzoxazone