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Overview

Avastin 100Mg Injection

Manufacturer: Roche Products India Pvt Ltd
Medicine composition: Bevacizumab
Prescription vs.OTC: Prescription by Doctor required

A monoclonal antibody and anti-angiogenesis, Avastin 100Mg Injection is used to treat types of brain tumor and types of cancers. This medication functions by interfering with the growth and spread of cancerous cells in the body.

It is advised that you seek medical attention immediately on experiencing any adverse effect. Common allergic reactions include swelling of facial features, hives, trouble breathing and abnormal bleeding from the mouth/nose/rectum/vagina/digestive tract/brain. Other side effects are vomiting, constipation, fever, chest pain, high blood pressure, irregular heartbeat, skin infection, back pain, missed periods and headache.

Before using this medication you should arrange for a consultation with your doctor and notify him/her if: you are allergic to it, your wounds heal very slowly, you have recently coughed up blood, you are scheduled for a surgery in the next 28 days, you have heart diseases/high blood pressure/bleeding or blood-clotting problems, you are taking any other medications, you are pregnant or are breastfeeding a baby. Ensure not to conceive for at least 6 months after end of treatment.

This medication is administered into a vein via IV injection once in every 2-3 weeks. The dosage needs to be prescribed by the doctor based on your medical history and current condition.

cancer of colon and rectum
, cancer of fallopian tube and
kidney cancer
.
In addition to its intended effect, Avastin 100Mg Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Headache
Altered taste
Rectal haemorrhage (bleeding)
Lacrimation disorder
Exfoliative dermatitis
Dry skin
Increased blood pressure
Protein in urine.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Bevatas 100mg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Patients may experience somnolence asyncope , and they should avoid driving or operating machinery.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Avastin 100Mg Injection, and hence can be used as its substitute.
Intas Pharmaceuticals Ltd
Are there any missed dose instructions?
If you miss a dose of Bevacizumab, please consult your doctor.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
What are you using Avastin 100Mg Injection for?
Other
cancer of colon and rectum
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Will the bulging of retina be cured after Avastin injection and laser treatment ?

Phaco Development Program, Fellowship in Pediatric Ophthalmology, DNB Ophtalmology, MBBS
Ophthalmologist, Mysore
It is not bulging. It is called as edema. Avastin and laser will definitely help but if your sugar levels are not under strict control then no measures in the world will help you. Keep your sugar levels under strict control no matter what.

I forgot to keep bevatas in refrigerator for almost 6 hrs, still we can use the same? Bevatas (Avastin)

MBBS, M.S. General Surgery, M.R.C.S. England, M.Ch. Surgical Oncology, DNB Surgical Oncology, FEBS Surgical Oncology, DNB General Surgery, MNAMS, FMAS, FIAGES, FAIS, FICS, FEBS Breast Surgery, FACS, Fellowship IFHNOS & MSKCC USA, Fellowship in breast and oncplastic Surgery
Oncologist, Mumbai
Bevacizumab is usually found to be stable, under sterile conditions, for 3 months at 4°C and for 7 days at room temperature, exposed to indirect light sources, while a brief exposure of the drug to direct UV radiation proves detrimental to drug stability (decreased activity). Hence if exposed to direct sunlight, efficacy of the drug would have decreased. If not, then should be ok to use the same. Feel free to contact me directly if you want to discuss this further.

Mother is a diabetic age 69 has ckd blood pressure thyroid She is having blurred vision and is suggested avastin inj. Want to know for which problem avastin inj is given.

MBBS
Internal Medicine Specialist, Kendujhar
Mother is a diabetic age 69 has ckd blood pressure thyroid
She is having blurred vision and is suggested avastin inj....
Hello, Thanks for your query on Lybrate "As" per your query is concerned (AVASTIN INJ) contains (bevacizumab) which belongs to the class of monoclonal antibodies, Used in the treatment of cancer. So check with your treating Doctor if she has breast cancer or not. Hope that helps.

I have shadow visibility in my left eye. I am diabetic. I got twice injection - avastin in my eye but no improvement in sjght. Can it be cured?

MD - Ophthalmology
Ophthalmologist, Amritsar
The shadow could be due to a minor bleed or otherwise. Diabetic eye disease cannot be cured but it certainly be treated . Avastin and laser treatment can sometimes be very helpful. You are in the right direction.

What will be the cheapest cost of Avastin injection for AMD as my father has been diagnosed with that in 1 eye.

Fellowship In Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
What will be the cheapest cost of Avastin injection for AMD as my father has been diagnosed with that in 1 eye.
Hello charges for avastin injection varies as per city and hospital it may range from 7000 to 12000 per injection.
1 person found this helpful

Popular Health Tips

DIABETIC RETINOPATHY

MS - Ophthalmology, MBBS
Ophthalmologist, Jaipur
DIABETIC RETINOPATHY
Diabetes is known to cause total and irreparable blindness if not attended in time. It is important that every deiabetic patient if fully examined by an expert ophthalmologist. There are certain drugs which can prevent damage to retina. Once the retina is involved, we cal it diabetic retinopathy which if not attended can lead to vitreous haemorrhage and retinal detachment which finally may lead to total and irreparable blindness. Timely intervention in cases of diabetic retinopathy by oct examination may reveal changes which can be reversed by photocoagulation and more effectively by intravitreal injections of lucentis or avastin.
23 people found this helpful

8 Common Causes of Age Related Macular Degeneration (AMD)!

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
8 Common Causes of Age Related Macular Degeneration (AMD)!

Macular Degeneration is an age-related macular degeneration incurable eye disease, which might result in blurred vision or no vision in the centre of the vision field, which might lead to visual distortions, reduced central vision, decreased intensity of the colours and can make it difficult for the patient to recognize faces, read, drive and to perform other activities.

Types of Macular Degeneration
1. Dry Macular Degeneration: It is characterized by the presence of drusen and thinning of macula because of a breakdown or thinning of the layer of retinal pigment epithelial cells in the macula.

2. Wet macular degeneration: In this type of AMD, there is an excessive growth of blood vessels, which causes bleeding, leakage, as well as scaring under the retina, which results in a rapid and severe loss of the central vision and might become permanent if not treated.

Causes of Age-related Macular Degeneration:
This is caused due to a problem related to the part of eye known as Macula, which is a spot at the centre of the retina of the eye. The focus point of the incoming ray of light is on Macula, which is responsible for see the things direct in front of us, especially reading and writing.

  1. Age: As the age increases, the probability of developing Age-related Macular Degeneration also increases significantly. The degree of the macular degeneration might vary person to person, but ageing is a major cause of suffering from age-related macular degeneration.
  2. Smoking: Smoking increases the chances of developing the disease in comparison to someone who does not smoke. The longer you have smoked, the more are the chances of developing it.
  3. Family History: The risk of developing the Age-related Macular Degeneration increases if it runs in your family, i.e. if your parents and siblings are suffering from it, then your chances of developing it are quite high as compared to the ones who do not have any family history.
  4. Obesity: The obese people have the higher chances of developing Age-related Macular Degeneration.
  5. Alcohol: Higher alcohol consumption also puts you at the risk of AMD, which is why one should always take alcohol in limited quantity only.
  6. Sunlight: As going out in sunlight without sunscreen is harmful to your skin, the same is harmful to your eyes for longer duration, and one should always wear UV-absorbing sunglasses to protect his eyes from AMD.
  7. Ethnicity: The white and Chinese are more prone to developing AMD as compared to the black people.
  8. Cardiovascular disease: the persons who have suffered diseases that affect the heart and other blood vessel are at higher risk of macular degeneration.

Treatment of Age-related Macular Degeneration
1. Anti-VEGF Drugs: The dry macular degeneration cannot be cured while the wet macular degeneration can be stabilized and maintained with a number of medical treatments to be injected into the eye, such as Lucentis, Avastin and Eylea. These are not long procedures and continued monitoring of the vision to maintain or improve the vision.

2. Laser photocoagulation: It consists of a concentrated beam of high energy thermal light that is directed towards the retina to obliterate and seal leaking blood vessels.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4905 people found this helpful

Age-related Macular Degeneration (AMD) - 8 Common Causes

Ophthalmologist
Ophthalmologist, Thane
Age-related Macular Degeneration (AMD) - 8 Common Causes

Macular Degeneration is an age-related macular degeneration incurable eye disease, which might result in blurred vision or no vision in the centre of the vision field, which might lead to visual distortions, reduced central vision, decreased intensity of the colours and can make it difficult for the patient to recognize faces, read, drive and to perform other activities.

Types of Macular Degeneration
1. Dry Macular Degeneration: It is characterized by the presence of drusen and thinning of macula because of a breakdown or thinning of the layer of retinal pigment epithelial cells in the macula.

2. Wet macular degeneration: In this type of AMD, there is an excessive growth of blood vessels, which causes bleeding, leakage, as well as scaring under the retina, which results in a rapid and severe loss of the central vision and might become permanent if not treated.

Causes of Age-related Macular Degeneration:
This is caused due to a problem related to the part of eye known as Macula, which is a spot at the centre of the retina of the eye. The focus point of the incoming ray of light is on Macula, which is responsible for see the things direct in front of us, especially reading and writing.

  1. Age: As the age increases, the probability of developing Age-related Macular Degeneration also increases significantly. The degree of the macular degeneration might vary person to person, but ageing is a major cause of suffering from age-related macular degeneration.
  2. Smoking: Smoking increases the chances of developing the disease in comparison to someone who does not smoke. The longer you have smoked, the more are the chances of developing it.
  3. Family History: The risk of developing the Age-related Macular Degeneration increases if it runs in your family, i.e. if your parents and siblings are suffering from it, then your chances of developing it are quite high as compared to the ones who do not have any family history.
  4. Obesity: The obese people have the higher chances of developing Age-related Macular Degeneration.
  5. Alcohol: Higher alcohol consumption also puts you at the risk of AMD, which is why one should always take alcohol in limited quantity only.
  6. Sunlight: As going out in sunlight without sunscreen is harmful to your skin, the same is harmful to your eyes for longer duration, and one should always wear UV-absorbing sunglasses to protect his eyes from AMD.
  7. Ethnicity: The white and Chinese are more prone to developing AMD as compared to the black people.
  8. Cardiovascular disease: The persons who have suffered diseases that affect the heart and other blood vessel are at higher risk of macular degeneration.

Treatment of Age-related Macular Degeneration
1. Anti-VEGF Drugs: The dry macular degeneration cannot be cured while the wet macular degeneration can be stabilized and maintained with a number of medical treatments to be injected into the eye, such as Lucentis, Avastin and Eylea. These are not long procedures and continued monitoring of the vision to maintain or improve the vision.

2. Laser photocoagulation: It consists of a concentrated beam of high energy thermal light that is directed towards the retina to obliterate and seal leaking blood vessels. If you wish to discuss about any specific problem, you can consult an ophthalmologist.

4051 people found this helpful

Excessive Sunlight Exposure - Can It Cause Age-related Macular Degeneration?

MBBS, MD - Ophthalmology, Fellowship in Vitreo Retina, Fellowship in Cornea
Ophthalmologist, Bangalore
Excessive Sunlight Exposure - Can It Cause Age-related Macular Degeneration?

Macular Degeneration is an age-related macular degeneration incurable eye disease, which might result in blurred vision or no vision in the centre of the vision field, which might lead to visual distortions, reduced central vision, decreased intensity of the colours and can make it difficult for the patient to recognize faces, read, drive and to perform other activities.

Types of Macular Degeneration
1. Dry Macular Degeneration: It is characterized by the presence of drusen and thinning of macula because of a breakdown or thinning of the layer of retinal pigment epithelial cells in the macula.

2. Wet macular degeneration: In this type of AMD, there is an excessive growth of blood vessels, which causes bleeding, leakage, as well as scaring under the retina, which results in a rapid and severe loss of the central vision and might become permanent if not treated.

Causes of Age-related Macular Degeneration:
This is caused due to a problem related to the part of eye known as Macula, which is a spot at the centre of the retina of the eye. The focus point of the incoming ray of light is on Macula, which is responsible for see the things direct in front of us, especially reading and writing.

  1. Age: As the age increases, the probability of developing Age-related Macular Degeneration also increases significantly. The degree of the macular degeneration might vary person to person, but ageing is a major cause of suffering from age-related macular degeneration.
  2. Smoking: Smoking increases the chances of developing the disease in comparison to someone who does not smoke. The longer you have smoked, the more are the chances of developing it.
  3. Family History: The risk of developing the Age-related Macular Degeneration increases if it runs in your family, i.e. if your parents and siblings are suffering from it, then your chances of developing it are quite high as compared to the ones who do not have any family history.
  4. Obesity: The obese people have the higher chances of developing Age-related Macular Degeneration.
  5. Alcohol: Higher alcohol consumption also puts you at the risk of AMD, which is why one should always take alcohol in limited quantity only.
  6. Sunlight: As going out in sunlight without sunscreen is harmful to your skin, the same is harmful to your eyes for longer duration, and one should always wear UV-absorbing sunglasses to protect his eyes from AMD.
  7. Ethnicity: The white and Chinese are more prone to developing AMD as compared to the black people.
  8. Cardiovascular disease: the persons who have suffered diseases that affect the heart and other blood vessel are at higher risk of macular degeneration.

Treatment of Age-related Macular Degeneration
1. Anti-VEGF Drugs: The dry macular degeneration cannot be cured while the wet macular degeneration can be stabilized and maintained with a number of medical treatments to be injected into the eye, such as Lucentis, Avastin and Eylea. These are not long procedures and continued monitoring of the vision to maintain or improve the vision.

2. Laser photocoagulation: It consists of a concentrated beam of high energy thermal light that is directed towards the retina to obliterate and seal leaking blood vessels.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4319 people found this helpful

CCMTD, CCEBDM, C.Diabetology, American Diabetes Association, DOMS, MBBS, Masters in endocrinology
Endocrinologist, Mumbai
Diabetic macular oedema ( DME ) is severe form of Diabetic Retinopathy affecting vision.
DME can occur in any stage of diabetes.
Thus, the importance of regular eye check-up for diabetic patients is must. At least once in a year get your eyes fully tested.
Most of the people are unaware of this complication. And many times when I ask my patient about eye test I get answers like , "I got my eye glasses power checked and changed or I don't have cataract. "
Eye check-up for diabetic person is checking the back part of the eye which is called as Retina.
Once DME is diagnosed, immediate treatment is necessary to ensure better outcomes and prevent vision loss.

Diabetic macular oedema (DME) can be treated using laser therapy and/or intravitreal injections with vascular endothelial growth factor (VEGF) inhibitor injections.


Anti-VEGFs are able to reduce oedema, macula thickening and vascular permeability
They are the treatment of choice for DME because they can improve the patient’s vision ,produce good results and have a low risk of complications.

3 anti-VEGFs are available in market. bevacizumab and ranibizumab, aflibercept .

In some patients, there may be a need for a combination therapy of both laser treatment and intravitreal anti-VEGF injections. DME treatment needs to be personalised to cater to each patient’s conditions. This applies to the frequency of intravitreal anti-VEGF injections, with the injections given as per the patient’s condition instead of following a strict routine frequency protocol.


9 people found this helpful