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Amlodipine

Prescription vs.OTC: Prescription by Doctor required

Amlodipine acts as a calcium channel blocker that improves blood flow by dilating blood vessels. It is used to treat angina, high blood pressure and coronary heart disease. It is recommended in case of heart failure if other medications fail to work. Amlodipine is administered orally and its effects last for at least a day.

Some side effects of Amlodipine include swelling, abdominal pain, feeling tired and nausea. Serious side effects include low blood pressure or a mild heart attack. The medicine may not be safe to use during pregnancy or breastfeeding. Dosage should be low for elderly people and for those with liver problems. If you have heart problems then intake of Amlodipine may increase your health problems. It is not approved to be used by anyone who is 6 years of age or younger. Intake of alcohol along with this medicine may increase its side effects.

The usual dose for Amlodipine is 5mg to 10 mg, taken orally once a day for as long as prescribed the doctor. The dosage is later adjusted depending on your reaction to the first dose. It is often times used in combination with other anti-hypertensive and anti-anginal medicines. If you miss a dose then take the next dose as soon as possible. If it is nearly time for the next one, then you should skip the missed dose. In case of overdosing, seek medical attention immediately.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Cardiologist before using this medicine.

Amlodipine is used in the treatment of hypertension which is an increase in the blood pressure caused by genetic and environmental factors.

Angina Pectoris

Amlodipine is used in the treatment of Angina Pectoris which is a type of heart disease characterized by chest pain caused due to emotional stress and smoking.
Avoid if you have a known allergy to Amlodipine or any medicine of the same class.
In addition to its intended effect, Amlodipine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Swelling of ankles or feet

Major Common

Difficulty in breathing

Major Less Common

Dizziness

Major Less Common

Increased heartbeat

Major Less Common

Redness of face, neck, arms and chest

Major Less Common

Muscle pain

Major Rare

Heartburn

Minor Less Common

Acid or sour stomach

Minor Less Common

Stomach pain

Minor Less Common

Anxiety

Minor Rare

Diarrhea

Minor Rare

Constipation

Minor Rare

Sweating

Minor Rare

How long is the duration of effect?

This effect of this medicine lasts for a duration of approximately 24 hours.

What is the onset of action?

The peak effect of this medicine can be observed in 6 to 12 hours.

Are there any pregnancy warnings?

This medicine is recommended only if clearly needed and no other safer alternative is available.

Is it habit forming?

No habit forming tendency has been reported.

Are there any breast-feeding warnings?

Clear data is not available on the use of this medicine in breastfeeding women. This medicine should be used only if clearly needed and no other safer alternative is available.

Missed Dose instructions

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of overdose.

India

United States

Japan

Below is the list of medicines, which contains Amlodipine as ingredient
Cipla Ltd
Orchid Chemicals & Pharmaceuticals Ltd
Micro Labs Ltd
Micro Labs Ltd
Shreya Life Sciences Pvt. Ltd
Alkem Laboratories Ltd
Zydus Cadila
Mankind Pharmaceuticals Ltd
Dr. Reddys Laboratories Ltd
Dr. Reddys Laboratories Ltd
Micro Labs Ltd
Cadila Pharmaceuticals Ltd
Parenteral Drugs (India) Ltd
Baroda Pharma Pvt. Ltd
Zydus Cadila
Shine Pharmaceuticals Ltd
Zydus Cadila
Caplet India Private Limited
Amlodipine is an calcium channel blockers. It works by inhibiting the entry of calcium into the cardiac and vascular smooth muscles and prevents the contraction of the muscles and thereby reduces the blood pressure.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Hypotension or cardiogenic shock

Major
Amlodipine is not recommended in patients suffering from hypotension or cardiogenic shock as it further reduces the blood pressure.

Interaction with Alcohol

Alcohol

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Grapefruit juice

Minor
Consumption of grapefruit juice is not recommended as it increases the concentration of Amlodipine. Inform the doctor if you experience dizziness, headache, swelling of hands and feet is necessary.

Interaction with Medicine

Carbamazepine

Moderate
The desired effect of Amlodipine will not be achieved if taken with carbamazepine. Inform the doctor if you are on either of the medicines. Frequent monitoring of blood pressure is necessary. An alternate medicine or suitable dose adjustments are to be made based on the clinical condition.

Dexamethasone

Moderate
The desired effect of Amlodipine will not be achieved if taken with dexamethasone. This interaction is more likely to happen if dexamethasone is taken for more than a week. Inform the doctor if you are on either of the medicines. Frequent monitoring of blood pressure is necessary. An alternate medicine or suitable dose adjustments are to be made based on the clinical condition.

Itraconazole

Major
Itraconazole may increase the concentration of Amlodipine and may cause serious adverse effects such as fluid retention, irregular heart rhythm, and low blood pressure. Inform the doctor if you are on either of the medicines. Frequent monitoring of blood pressure is necessary. An alternate medicine or suitable dose adjustments are to be made based on the clinical condition.

Rifampin

Major
The desired effect of Amlodipine will not be achieved if taken with rifampin. Inform the doctor if you are on either of the medicines. Frequent monitoring of blood pressure is necessary. An alternate medicine or suitable dose adjustments are to be made based on the clinical condition.
What are you using Amlodipine for?
Hypertension
Other
Angina Pectoris
Fever
How much was the improvement?
Excellent
Average
Poor
How long did it take before seeing improvement?
Within 2 hours
More than 2 days
Within a day
Within 6 hours
Within 2 days
How frequently did you take this medicine?
Once a day
Twice a day
How did you take this medicine?
With Food
With or without food
What were the side effects of this medicine?
Dizziness
Swelling of ankles or feet
Increased heartbeat
arms and chest
Muscle pain
neck
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

My friend 21 years old yesterday he took 5 mg amlodipine *25=125 mg amlodipine. Now what we can do for him? please suggest me.

MBBS, MD - Internal Medicine, DM - Cardiology, Fellowship in EP
Cardiologist, Delhi
My friend 21 years old yesterday he took 5 mg amlodipine *25=125 mg amlodipine. Now what we can do for him? please su...
Keep him in hospital for 3 days, should be fine if they clean out his stomach and provide supportive care.
1 person found this helpful

My doctor said I have to take amlodipine for lifetime. Because my bp is 130/90. We have a family background of high blood and stroke. But I research about amlodipine it has a side effect for liver. Is my doctor right or wrong?

MBBS
General Physician, Mumbai
My doctor said I have to take amlodipine for lifetime. Because my bp is 130/90. We have a family background of high b...
As of now follow your doctors advice and liver side effects is negligible with amlodipine but just imagine if you don’t take medication than what all can be damaged in your body with high Bp

I think amlodipine cause my heart pounding - palpitation. Like its racing. Should I stop amlodipine and take only atenolol ? Or any other alternative ?

MBBS, MD - General Medicine
General Physician, Delhi
I think, first you check your tsh and ecg, pounding of heat may not be because of amlodac. Rule out other causes first.
2 people found this helpful

For blood pressure I am using telesmartin 40 mg and amlodipine 5 mg Can I reduce the dose either of two or both of the tablet I am using in future.

PGP In Diabetologist, Fellowship in Non-Invasive Cardiology, MD - Medicine, MBBS
Endocrinologist, Delhi
For blood pressure I am using telesmartin 40 mg and amlodipine 5 mg Can I reduce the dose either of two or both of th...
Yes, you can try that gradually under medical supervision and see how it goes. But it depends on various factors.
7 people found this helpful

Sir I have prescribed with amlodipine 5 mg twice and minipress xl 2.5.Is it safe to take minipress for the first time as I have heard it causes fainting?

MD - Medicine, Bachelor of Ayurveda, Medicine and Surgery (BAMS), Post Graduate Certficate in Ksharsutra & Ano-Rectal Diseases
Ayurveda, Mumbai
Sir I have prescribed with amlodipine 5 mg twice and minipress xl 2.5.Is it safe to take minipress for the first time...
Dear lybrate-user, it seems you are obese & also developing its related complicatins too. Be careful, you needed comprehnsive mansgement. For emergency management allopathy drug can be taken. But for prolong use they may cause some serious side effects. First you go for proper investigations, correct diagnosis & find out causes of your illness. Once it is done then second stage of comprehensive msnagement will starts. Nap therapy is ultimate treatment for your problems. Nap therapy is safe, fast effective. It will prevent future problems & also protect - preserves your all vital organs like - heart, kidney liver, brain, lungs. For complete management consult.
2 people found this helpful

Popular Health Tips

Pulmonary Hypertension - What Type Of Treatment Is Given?

MD , MBBS
Pulmonologist, Delhi
Pulmonary Hypertension - What Type Of Treatment Is Given?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying. If you wish to discuss about any specific problem, you can consult a Pulmonologist.
2516 people found this helpful

Pulmonary Hypertension: How to Treat It?

MD - Pulmonary, DTCD
Pulmonologist, Faridabad
Pulmonary Hypertension: How to Treat It?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying.
8743 people found this helpful

How To Treat Pulmonary Hypertension?

DTCD (TDD), C-HIV
Pulmonologist, Pune
How To Treat Pulmonary Hypertension?

Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.

There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Common Treatments for pulmonary hypertension:

Medications:

  1. Blood vessel dilators (vasodilators): Vasodilators open narrowed blood vessels. They are one of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that the effect lasts only for few minutes. This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.
  2. Ventavis: Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.
  3. Treprostinil (Tyvaso, Remodulin, Orenitram): It is another form of the drug, which can be given four times a day and can be inhaled or can be taken as an oral medication and can also be administered through injection.
  4. Endothelin receptor antagonists: These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.
  5. Sildenafil and tadalafil: Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.
  6. High-dose calcium channel blockers: These drugs help relax the muscles in the walls of your blood vessels. They include medications, such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.
  7. Soluble guanylate cyclase (SGC) stimulator: Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.
  8. Anticoagulants: Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications. Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.
  9. Digoxin: Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.
  10. Diuretics: Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.
  11. Oxygen: Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries:

  1. Atrial Septostomy: If medications don't control your pulmonary hypertension, this open heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.
  2. Lung Transplantation: In some cases, a lung or heart lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications:

  1. The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail
  2. Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying. If you wish to discuss about any specific problem, you can consult a Pulmonologist.
1872 people found this helpful

Pulmonary Hypertension - How Can It Be Treated?

Fellowship In Minimal Access Surgery, M.Ch - Cardio Thoracic & Vascular Surgery
Pulmonologist, Hyderabad
Pulmonary Hypertension - How Can It Be Treated?

Pulmonary hypertension mainly occurs from narrowing of the arteries of the lungs as a result of which blood-flow can be restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus heart gets adversely affected.

The blood pressure of your body will get increased to a great extent if this situation remains untreated, and thus you might face dreadful consequences, especially heart failure, serious pulmonary diseases, blood-clots in lungs, congenial heart-defects and others.

Some forms of pulmonary hypertension are serious conditions that become progressively worse and are sometimes fatal. Although some forms of pulmonary hypertension aren't curable, treatment can help lessen symptoms and improve your quality of life.

It often takes some time to find the most appropriate treatment for pulmonary hypertension. The treatments are often complex and require extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective.

When pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.

Commonest Treatments for Pulmonary Hypertension-

Medications...

Blood vessel dilators (vasodilators). Vasodilators open narrowed blood vessels. One of the most commonly prescribed vasodilators for pulmonary hypertension is epoprostenol (Flolan, Veletri). The drawback to epoprostenol is that its effects last only a few minutes.

This drug is continuously injected through an intravenous (IV) catheter via a small pump that you wear in a pack on your belt or shoulder.

Another form of the drug, iloprost (Ventavis), can be inhaled six to nine times a day through a nebulizer, a machine that vaporizes your medication. Because it's inhaled, it goes directly to the lungs.

Treprostinil (Tyvaso, Remodulin, Orenitram), another form of the drug, can be given four times a day. It can be inhaled, taken as oral medication or administered by injection.

Endothelin receptor antagonists. These medications reverse the effect of endothelin, a substance in the walls of blood vessels that causes them to narrow. These drugs may improve your energy level and symptoms. However, these drugs shouldn't be taken if you're pregnant. Also, these drugs can damage your liver and you may need monthly liver monitoring.

Sildenafil and tadalafil. Sildenafil (Revatio, Viagra) and tadalafil (Cialis, Adcirca) are sometimes used to treat pulmonary hypertension. These drugs work by opening the blood vessels in the lungs to allow blood to flow through more easily.

High-dose calcium channel blockers. These drugs help relax the muscles in the walls of your blood vessels. They include medications such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac, others) and nifedipine (Procardia, others). Although calcium channel blockers can be effective, only a small number of people with pulmonary hypertension respond to them.

Soluble guanylate cyclase (SGC) stimulator. Soluble guanylate cyclase (SGC) stimulators (Adempas) interact with nitric oxide and help relax the pulmonary arteries and lower the pressure within the arteries. These medications should not be taken if you're pregnant. They can sometimes cause dizziness or nausea.

Anticoagulants. Your doctor is likely to prescribe the anticoagulant warfarin (Coumadin, Jantoven) to help prevent the formation of blood clots within the small pulmonary arteries. Because anticoagulants prevent normal blood coagulation, they increase your risk of bleeding complications.

Take warfarin exactly as prescribed, because warfarin can cause severe side effects if taken incorrectly. If you're taking warfarin, your doctor will ask you to have periodic blood tests to check how well the drug is working. Many other drugs, herbal supplements and foods can interact with warfarin, so be sure your doctor knows all of the medications you're taking.

Digoxin. Digoxin (Lanoxin) can help the heart beat stronger and pump more blood. It can help control the heart rate if you experience arrhythmias.

Diuretics. Commonly known as water pills, these medications help eliminate excess fluid from your body. This reduces the amount of work your heart has to do. They may also be used to limit fluid buildup in your lungs.

Oxygen. Your doctor might suggest that you sometimes breathe pure oxygen, a treatment known as oxygen therapy, to help treat pulmonary hypertension, especially if you live at a high altitude or have sleep apnea. Some people who have pulmonary hypertension eventually require continuous oxygen therapy.

Surgeries-

Atrial Septostomy. If medications don't control your pulmonary hypertension, this open-heart surgery might be an option. In an atrial septostomy, a surgeon will create an opening between the upper left and right chambers of your heart (atria) to relieve the pressure on the right side of your heart.

Lung Transplantation. In some cases, a lung or heart-lung transplant might be an option, especially for younger people who have idiopathic pulmonary arterial hypertension.

Reducing Complications-

The complications need to be reduced by taking proper health care. Healthy diet needs to be taken regularly along with proper medications. Smoking should be stopped and exercising sessions should be attended daily without any fail.

Overweight or obesity needs to be controlled properly for reducing the complications. Specialized caring strategies need to be maintained for avoiding severe kinds of health complications that are quite annoying.

3694 people found this helpful
Table of Content
About Amlodipine
When is Amlodipine prescribed?
What are the contraindications of Amlodipine ?
What are the side effects of Amlodipine ?
Key highlights of Amlodipine
What are the dosage instructions?
Where is the Amlodipine approved?
Medicines containing Amlodipine
How does medicine works?
What are the interactions for Amlodipine ?