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Akt-4 Kit Health Feed

Asked for female, 21 years old from Guntur

21 years old female of weight 70 kg with cervical lymph adenopathy diagnosed with chronic granulomatous lymphadenitis. She was on att prescribed by doc .on 10 days of usage she developed severe rash on whole body with fever .on stoppage they subsided doc has reduced the dose even then developed rash and fever .and next time on every usage she developed severe rash and fever even when individual tablets (single dose) are given for all h, r,z, e at present she stopped medication ethambutol 1800 mg pyrazinamide single tablet ke vachindulhi actual ga 3 tablets 750 mg isoniazid 300 mg rifampin 600 mg. What is the solution for this doc !pls reply.

Dr. Sushma Shah93%(9037 ratings)

MBBS

General Physician•Vadodara

it's a very common problem. my brother had same problem 5-6 yrs back. they do titration dose slowly slowly start with 25 mg n gradually increase, add inj streptomycine for two months.
treating doctor will find out alternate therapy.

Asked for male, 29 years old from Howrah

I am diagnosed TB for 2nd time. Rifampin resistant not detected. I am taking rcinex 300/450 once, pyzina 750 2 tablets, ethambutol 800 for 30 days. Now another doctor told me to take injection streptomycin .Will it be right to take injection now?

Dr. Amit Kumar Poddar92%(932 ratings)

MBBS, MD TUBERCULOSIS AND CHEST DISEASES...read more

Pulmonologist•Kolkata

Rifampicin resistance not detected means Rifampicin INH pyrazinamide Ethambutol are to be taken in the requisite doses. There's no need of streptomycin injection.
Wish you good health.
Meticulous treatment adherence till cure is recommended to prevent relapse or complications.

310 people found this helpful

Asked for male, 32 years old from Hyderabad

My father aged 68, some 8 months back was diagnosed for Spine TB and he started on AKT4 for 2 months, AKT3 for the next month but had to stop due to vision loss and following 5 months was taking Rifampicin and Isoniazid. His vision is almost back with some eye power complaint but he is complaining about arm pain midway from shoulder joint and elbow. I read that Isoniazid can cause these side effects. Also recent blood report shows hemoglobin at 10.9. I read this could be due to Rifampicin. What could be the reason and if it needs any urgent attention to treatment? FYI. He is taking 40 mg of pyridoxine, his blood work shows platelet count=130, ESR 94, CRP has come down from 67 to 8.4, LFT results are normal, His back pain is almost gone. Other symptoms at this moment are slight numbness around feet, constipation and dizziness upon movement. Remarks of Hemogram: RBCs: Mild anisopoikilocytosis. Predominantly macrocytic normochromic with macroovalocytes. WBCs: Mild Leukopenia is present. Platelets: Appear mildly reduced in smear. Macroplatelets are seen. Sugar levels are normal 93/142 Blood pressure is bit low 75/115.

Dr. Mool Chand Gupta95%(37146 ratings)

MD - Pulmonary, DTCD

Pulmonologist•Faridabad

Arm pain is nothing to do with TB drugs. Haematological abnormality can be due to rifampicin, but not alrming to stop drug rifampicin.

60 people found this helpful

Asked for male, 29 years old from Delhi

I have stomach TB and completed 2 months with medicine pyrazinamide, macox plus, ethambutol. Doctor stop pyrazinamide for taking but from last night I have various episode of vomiting and stomach pain. Is this is due to medicine medicine change or something else and how many months I have to take macox plus and ethambutol combination.

Dr. Sajeev Kumar91%(40820 ratings)

C.S.C, D.C.H, M.B.B.S

Cardiologist•Alappuzha

The TB medication is for 9 months and pyrazinamide will cause nausea and vomiting and you can change if your doctor decides it

Asked for male, 32 years old from Hyderabad

My father aged 68, some 8 months back was diagnosed for Spine TB and he started on AKT4 for 2 months, AKT3 for the next month but had to stop due to vision loss and following 5 months was taking Rifampicin and Isoniazid. His vision is almost back with some eye power complaint. Recent blood report shows hemoglobin at 11.5. He has recently started to complaint about burning sensation while peeing and frequent urination. His Blood urea, BUN is high and so is creatinine = 1.77. I read that Rifampicin could induce such problems. I consulted general medicine doctor and he was concerned and asked to remove azulix (sugar medicine) and include nefrolex for 5 days and then redo the KFT. however he thing rifampicin could rarely cause this kind of toxicity. FYI. He is taking 40 mg of pyridoxine, his blood work shows platelet count=130, ESR 70, CRP has come down from 67 to 8.4, LFT results are normal, His back pain is almost gone. Remarks of Hemogram: RBCs: Mild anisopoikilocytosis. Predominantly macrocytic normochromic with macroovalocytes. WBCs: Mild Leukopenia is present. Platelets: Appear mildly reduced in smear. Macroplatelets are seen. Urine has pus cells loaded.

Dr. Arunesh Kumar91%(203 ratings)

MBBS, MRCP - General Medicine, MRCP-SCE,...read more

Pulmonologist•Gurgaon

The ATT regimen in Acute kidney injury is slightly different to normal. Please see a pulmonologist.

7 people found this helpful

Asked for female, 30 years old from Bangalore

Pls help me I hav tb infection and I am pregnant nw some Dr. r saying abort and one is saying keep so what to do.

Dr. Brahma Prakash

DNB(Respiratory Diseases), MBBS

Pulmonologist•Jabalpur

Normal tuberculosis (i. E not drug resistant) can be treated along with presence of pregnancy. Not to worry if one has been given rifampicin, isoniazid, ethambutol and pyrazinamide for treatment of tb along with pregnancy. So no need for abortion but regular consultation with gynaecologist for monitoring fetal well being growth and development is needed.

Health Query

Akt4 or forecox which tablet is better suggested for Tuberculosis? We consulted two doctors and both of them suggested 3 common medications and one suggested akt4 including other 3 and another doc suggested forecox including 3 other tablets which are common in both of their prescription. But the doc who suggested us forecox asked us to use it for 6 months where as the one suggested Akt4 asked us to use the dosage for 15 months! Can you pls suggest us the better medication out of these in detail. Thanks in advance.

Dr. Mool Chand Gupta95%(37146 ratings)

MD - Pulmonary, DTCD

Pulmonologist•Faridabad

AKT4 and FORECOX is both TB drugs. But niether of two contain TB medicine as per your weight requirement. Bette rtake all TB medicine as per weight

Asked for female, 30 years old from Trichy

My son is 3 and a half years old diagnosed with spinal tb. He had recurring fever and localized lower back pain. There was pain in his legs behind the knees and stiffness. He had difficulty walking. His gait was antalgic. His mri showed l5 s1 affected with epidural abscess. Mis bilateral decompression was done. They started him on att 3fdc (pyrazinamide 450 mg, rifampicin 225 mg, isoniazid 150 mg based on his weight 15.6 kg) and wysolone 25 mg (steroid prescribed for 1 month and gradually tapered and stopped at the end of 2 and a half months). After 3 months there was a recurrence in tb which spread to l4 and l3. To make the spine stable we have done instrumentation. Is this recurrence due to wysolone?

Dr. Amit Kumar Poddar92%(932 ratings)

MBBS, MD Tuberculosis And Chest Diseases...read more

Pulmonologist•Kolkata

this recurrence is not due to corticosteroid. total duration
should.be1 to*y 11/2yearst

Asked for male, 28 years old from Thane

9 months back, my mother was having 2 swelling seen in neck. We gone to doctor. Ent specialist. After several test like sonography, fnac it was detected as neck tb. There were total 5 in right neck with largest measuring 22 mm the doctor said to go with government medicines for tb. After 6 months course ,again sonography was done. All 5 were there size reduced with largest measuring 11 mm. Then again we were told to continue medicines for 3 months. In end of 8th month, my mother was not able to see properly. Blur vision. So we went to eye specialist, there 2 tests were done. One was for cornea and other for optic nerve damage .doctor said reports are normal and said it is due to tb medicine ethambutol. So he gave in writing to stop ethambutol. So we gone to government hospital to take medicines for for 9th month and told about blur vision. They gave 2 medicines. 1 was rifampicin and other was isoniazid. After taking for 1 month we did sonography again but now it showed lymph nodes swelling in left side also 3 to 4. And in right side largest measuring 10 mm. We told them government hospital. They told course is over. Now automatically it will go. Also vision will be clear. But it pains sometimes in neck. So they gave 1 month medicine rifampicin and isoniazid 1-1 tablet each day. They said treatment course is over but still swelling are there as in sonography. I am worried. Vision has improved slightly but not fully. Also do not know whom to ask ent or pulmonologist? please help.

Vandana Prabhu

MBBS, Diploma in Tuberculosis & Chest Di...read more

Pulmonologist•Bangalore

If 9 months of treatment is over, att should be stopped. In cervical tb lymphadenitis, the nodes in the neck may shrink/ enlarge or new nodes can appear on the other side, all happens during the course of treatment. This doesn't mean that att didn't work or tb wasn't cured. The nodes will eventually disappear, or tiny nodes may remain in the neck permanently.

108 people found this helpful

Asked for female, 25 years old from Raipur

I am taking anti tb drugs for intestinal tb. I take rifampicin and isoniazid 15 min before breakfast. Is it okay?

Dr. Surendra Kumar Chityala90%(16 ratings)

Diploma in Diabetology, MD - Pulmonary M...read more

Pulmonologist•West Godavari

Yes if you can tolerate and there is no vomiting and nausea the best time to take is before breakfast on empty stomach.

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