Post induction therapy treatment also known as consolidation therapy is a form of chemotherapy that is used to treat the condition of acute myeloid leukaemia (AML). The treatment is primarily focussed on killing any remaining leukaemia cells that the induction or remission therapy could not take care of, thus preventing the chances of relapse and making all efforts to restore the normal functioning of your bone marrow. There are three different options of post induction therapy for younger patients:
Several cycles of high-dose cytarabine chemo
Allogeneic stem cell transplant i.e. replacing dead stem cells with healthy donor cells
Autologous stem cell transplant i.e. replacing dead stem cells with own cells taken from other parts of the body
The consolidation therapy sticks to the use of cytarabine only. High dose of this particular drug is given to patients for over 5 days. The dose is repeated about every 4 weeks so as to complete 3-4 such cycles.
Apart from the use of cytarabine, another effective approach of treating acute AML is to give very high doses of chemotherapy for leukaemia followed by stem cell transplant treatment, which can either be allogeneic (from a donor) or autologous (patient's own) in nature. It has been proved that this transplantation treatment works wonderfully well in reducing the risk of relapsing leukaemia. But older patients or the ones with poor health condition may not be able to endure such exhaustive consolidation treatment. Such patients may be treated with a couple of cycles of cytarabine, but the dosage is usually not as high as the ones used in younger patients or a mini-transplant.
The treatment time depends on factors like the age of the patient, his health condition, the severity of cancer etc. and as for the treatment cost is concerned, it usually ranges from $30,000 - $45,000.