Lybrate.com has an excellent community of Oncologists in India. You will find Oncologists with more than 33 years of experience on Lybrate.com. You can find Oncologists online in Delhi and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.
Book Clinic Appointment
Submit a review for Dr. Robin KhosaYour feedback matters!
Dr. I'm 29 year old married women. Dr. Mujhe kuch dino se mere nipple mai pain ho raha hai halka sa. Aur nipple mai swelling bhi hai. please advice me.
The rising incidences of cancer have made it important for us to be vigilant about our health. It has been proven medically that if cancer is detected at an early stage -stage I & II , then the chances of cure and treatment along with full recovery are very high. For early cancer detection & for people at greater risk of cancer, PHC-Preventive Health Care plays a major role. Preventive Health Check is particularly important for the people who have a family history of cancer.
Almost all cancers are caused by damage or mutation in their genes, which, may be acquired from environmental exposure, dietary factors, hormones or through normal aging. In 90% of cases, these genes are not passed from parents to children. These are known as sporadic mutations and the cancers that they cause are called as sporadic cancers. But 5-10% of cancers are caused by gene mutations which are inherited from one or both parents & passed on to the children .These are hereditary or germline mutations & these cancers are known as hereditary or familial cancers.
People /children, who carry gene mutations have a higher risk of developing cancer at an earlier age or at some point in their life time.
Some of the common such cancers, which run in families, are:
- Breast cancer
- Ovarian cancer
- Colo-rectal cancer (cancer of large intestine )
- Prostate cancer
Breast, ovary & colo-rectal carcinoma have well established gene mutation studies.Mutation of BRCA 1 & BRCA2 Genes is responsible for 85% of hereditary breast cancers.
Estimated life time risk for developing breast cancer in woman with BRCA1 & BRCA2 mutation is 56-87% & risk for developing-bilateral /contralatral breast cancer is about 20-40%. These statistics make a preventive health check for women with breast cancer history in their family a necessity. Mutation in these genes confers about 20-40% increased life time risk for developing ovarian cancer. Hence the presence of gene mutation for breast cancer can trigger ovarian cancer.
However as stated above, other environmental and lifestyle factors can also cause breast cancer other than genetic BRCA1 & BRCA 2 gene mutations.
- Increasing age
- Early menarche
- Late menopause
- First birth after the age of 30
- Atypical lobular hyperplasia or Atypical ductal hyperplasia
- Prior breast biopsies
- Long term postmenopausal estiogen replacement
- Early exposure to ionizing radiation
Other Familial Cancers:
Familial cancer syndromes associated with colo-rectal cancers are familial adenomatous polyposis (FAP).It is an autosomal dominant inherited syndrome with more than 90% penetrance, manifested by hundreds of polyps developed by late adolescence .The risk of developing invasive cancer is almost 100% .So such patients should start getting colonoscopy at an earlier age- say by 20yr of age & should undergo Total Collectomy on development of significant polyps .
Other familial cancer syndromes are hereditary non -Polyposis Colo Rectal Cancer (HNPCC), Gardner's Syndrome, Turcot's Syndrome, Peutz-Jeghers Syndrome, Juvenile Polyposis.
Cancer Assessment & Conclusion:
For breast cancer risk assessment, we have the GAIL model & IBIS model, which take into consideration ,all the risk factors, apart from BRCA1 & BRCA 2 gene mutation. These models calculate the over all life time risk of development of breast cancer for any lady. For this, you have to consult a specialist experienced in area of hereditary cancers, cancer risk assessment, genetic counseling & testing.
To conclude, all people with cancers in their family should undergo genetic testing & counseling, to detect high risk individuals should take adequate measures & treatment.
My wife is having 2.9x2.1x1.8cm mass lesion in left breast of birads category 5. Advised biopsy by the report. What should be the best treatment available in india. I am very much worried. An early detailed reply will be appreciated.
I am 63 years diabetic. Type 1 since 15years having sugar level 190 ad 260pp taking humalog 20units morning 16 units night. I am bhp grade 1 with right renal lithiasis having stones of 7ad 9mm in right kidney. Due to enlarged prostrate I am facing frequent urination ad bladder is empty at one time. My hbaic is 8. 50 also having bp problems. One serious concern is erectile dysfunction ad premature ejaculaton. Can you suggest some safe medicine for ed ad premature ejaculate. For enlarged prostrate I am taking flotral alfuzion salt ad in addition to insulin I am taking vysov-, m ad diapride m-2. Please suggest safe medicine to cure the above problems. My lipid profile ad renal profile is normal. Please advise.
What is the symptoms of cancer and AIDS. What kind of medicine will be good for this disease. Please help me.
I am a 63 year old male detected with prostate problem - ct3anomo, ipsa -18-19, biopsy report/gleason score - 6. Question - what course of treatment - surgery, radiation and/or hormone therapy to accept so as to ensure least chances of incontinence and impotence.
I guess some limb has been grown in side my breast. I am really concerned regarding this. Kindly help me.
What is benign tumor and what is precautions to avoid from it how to remove and what types of drugs should be used.
I am 62 years Male. I have itching problem on testicles for the last one year. Itching happens only during urination. Infact I have prostate Gland enlargement problem for which I am taking Silodal 8 mg tab.
Some forms of cancer, such as cervical cancer can be prevented by vaccines. Cervical cancer is the second most common form of cancer that affects women. The vaccine that prevents cervical cancer is known as the human papilloma virus(HPV) vaccination. Let's take a look at a few things you should know about this vaccination.
What is HPV?
There are over a hundred types of HPV. While some of them affect the genital area and can cause abnormal tissue growth that leads to cervical cancer others can cause anal cancer, genital warts, skin warts, cancer of the head and neck and vaginal cancer.
When should you have the vaccination?
The human papillomavirus or HPV vaccination is most effective when administered to preteen and teenage girls. This vaccine protects them for the next ten years against the disease. One of the reasons, the HPV vaccination is given so early is that the virus can spread easily by sexual activity. Having the vaccination early can protect them from a HPV infection. The vaccine is also said to be more effective when given to girls who have not yet been infected by a strain of HPV.
How is the vaccination given?
The HPV vaccination is given in the form of three injections spread over six months. The second dose is given two months after the first dose and the final dose is administered six months after the first dose. There is more than one name for the HPV vaccination. Gardasil and cervarix are the most common amongst these. Many doctors suggest no matter which one you choose, the same vaccination be used for all three doses.
How effective is the vaccination?
Along with protecting against cervical cancer, the HPV vaccine also protects women against vaginal, anal and oropharynx cancer. Some of the vaccines also protect against genital warts. However, the vaccination cannot be used to treat existing HPV infections and is less effective when given to women who have already been infected with a strain of the virus.
Is there anyone who should not have this vaccine?
The HPV vaccine is not recommended for pregnant women. Do not have the vaccination if you are already suffering from a severe illness. The vaccination is also not recommended for women who are allergic to yeast or latex.
What are the side effects of the HPV vaccination?
The HPV vaccination has minor side effects that may include mild soreness at the injection site, a headache or low fever. Some women may also feel dizzy or faint after the injection. Nausea, vomiting, diarrhea and abdominal pain are some of the other side effects associated with this vaccination. Apart from taking a dose of vaccine, it is important that you go for regular full body check up as well, to prevent yourself from various ailments.