Urinary incontinence is a common problem that afflicts many adults around the world. Stress related urinary incontinence is a fairly common problem that afflicts many as well. This form of incontinence is usually caused by physical activity, which exerts pressure on the bladder and may cause the leakage of small amounts of urine.

Triggers and Symptoms for stress urinary incontinence
In terms of urinary problems, stress is used to describe physical problems in particular and not mental stress. So the triggers or risk factors of it could be any of the following:
1. Exercise
2. Jumping
3. Sneezing
4. Coughing
5. Exercises
6. Sexual activity

This form of urinary incontinence is very common in women who are older or have already been through menopause. It may also be common for women who have recently given birth or are pregnant. The urethra or the bladder may become prone to external stress and then involuntarily leak out some urine.

Causes
The causes can be quite varied from patient to patient but are primarily attributed to the weakening of the pelvic muscles, bladder or the sphincter. If any of these muscles open involuntarily due to physical stress, it leads to urine leaking out. Some of the causes which may lead to this are:
1. Pregnancy and childbirth: Pregnancy or childbirth related problems may cause damage to the urethra or sphincter during childbirth; leading to stress urinary incontinence.
2. Surgery of the prostate: Another common problem, especially with men, is with surgical interventions to correct prostate problems.
3. Menopause: Many older women often complain about stress incontinence after menopause due to the weakening of the muscles.
4. Pelvic surgery: Any surgery to the pelvic area or illnesses which may cause the muscles to become relaxed or act involuntarily due to external stress, may cause incontinence.
5. Weakening of the pelvic muscles: Certain illnesses may cause the pelvic muscles to become weak and thus cause the sphincter as well as the bladder to react involuntarily. UTIs or urinary tract infections have also been known to cause incontinence due to the same reason.
6. Obesity: Obesity has been known to put stress on many of the bodily systems and it may affect the bladder and the urinary sphincters as well.

Causes and Symptoms of Stress Urinary Incontinence

Renal Tubular Acidosis is a medical condition. When the kidney is unable to acidify urine, it leads to the accumulation of acid in the body. Usually, when blood is filtered by the kidney, it passes through the tubules of the nephrons (the functional unit of the kidney).

Before it flows into the bladder from the kidney, the urine undergoes an exchange of salts, acids and other solutes. Renal tubular acidosis results in the formation of excessive amounts of acid because the kidneys cannot drain them. This may happen because the kidneys cannot reabsorb the alkaline bicarbonate ions from the urine in the early segment of the nephron or because of inadequate production of acidic hydrogen ions in the latter half of the nephron.

Renal Tubular Acidosis is simply associated with abnormal urinary acidification. Other functions of the kidneys remain unimpaired.
There are several different types of renal tubular acidosis-

  Distal Renal Tubular Acidosis (RTA)
This is the most fundamental form of RTA. It is characterized when the hydrogen ions are not secreted into the lumen of the nephron by the alpha-intercalated cells of the medullary collective duct of the distal nephron. When this happens the pH of urine cannot be brought down below 5.3. Renal excretion is inhibited and hydrogen ions are not eliminated which leads to academia. At the same time, Potassium ions cannot be absorbed by the cell which leads to hypokalemia. The end result is protein retention and potassium excretion. Distal RTA can lead to the urinary stone formation, calcium deposits in the kidney, rickets and osteomalacia and Sjogren s syndrome.

  Proximal RTA
When proximal tubular cells reabsorb 85% of filtered bicarbonates and 60% of filtered sodium from the urine, then this again leads to academia. The distal intercalated cells, however, function normally and so the academia is not as severe as in case of Distal RTA. The alpha-intercalated cells can acidify urine to a pH of 5.3 or less because they produce hydrogen ions. Proximal RTA is also associated with Fanconi Syndrome which is characterized by aminoaciduria, uricosuria, glucosuria, and tubular proteinuria.

  Combined distal and proximal RTA
Inherited carbonic anhydrase II deficit leads to combined distal and proximal RTA. This is accompanied by osteopetrosis, cerebral calcification, and renal tubular acidosis. Cases of combined distal and proximal RTA are very rare.

How is RTA understood?
The following steps are applied to analyze Renal Tubular Acidosis-
  Determining the anion gap in acidosis. The normal Anion Gap is 8-12 (4-6 mEq/L)
  Separating the renal from the extrarenal causes of normal anion gap acidosis
  Classifying the types of RTA
  If it is distal RTA, further tests will be necessary to support the diagnosis

How is RTA diagnosed?
Three types of tests can reveal if a person is affected by Renal Tubular Acidosis-
  Urine test
  Acid load test
  Physical examination

Treatment of RTA-
Doctors prescribe either or both of the following two types of therapies-

  Alkali therapy- The pH level of urine is restored and electrolytes are balanced
  Vitamin D supplements- If RTA leads to bone deformities or rickets, your doctor will prescribe vitamin supplements to strengthen your bones.

Timely diagnosis can prevent the effects of Renal tubular Acidosis from becoming compounded. With the right medication, a person can lead a healthy normal life.

What Should You Know About Renal Tubular Acidosis?

The kidneys may be a pair of small organs but they perform a very important function. Without the kidneys, it is impossible to filter blood and remove toxins from the body. One of the common problems associated with kidneys is the development of a kidney stone. This can be described as a hard, pebble like substance that is formed when urine contains high levels of certain minerals. Kidney stones vary in size and shape. Small stones may pass through the ureter into the bladder and out of the body with minimal discomfort. However, in some cases, a kidney stone can be as large as a golf ball. In such cases, it can block the urine flow and cause extreme amounts of pain as well as bleeding. In such cases, a doctor needs to be consulted as early as possible.

There are four different types of kidney stones.

Calcium Stones: This is the most common type of kidney stones. It is caused by excess calcium that is not flushed out with the urine.
Uric acid stones: Highly acidic urine can trigger the development of such stones. This may be caused by excessive consumption of meat, fish and shell fish.
Struvite stones: This is often formed as a side effect of Urinary tract infections. These stones may develop and grow rapidly.
Cystine stones: These stones are formed as a result of a genetic disorder known as cystinuria. This disorder causes an amino acid known as cysteine to leak into the urine.
Kidney stones are a fairly common occurrence. It affects both men and women but men have a higher risk of developing kidney stones as compared to women. Other risk factors that can influence kidney stones are:

Family history of kidney stones
Not drinking enough water
Obesity
Digestive problems
Recurrent UTIs
Gout
Bowel inflammation
Disease that causes blockage of the urinary tract
Certain medications such as diuretics or calcium based antacids
Once a person has been diagnosed with a kidney stone, this issue can recur. Treatment for kidney stones depends on the type of stones, size and location. In most cases, medication is prescribed to help break the stone down into smaller parts so that it can pass through urine. In extreme cases, surgery may be required. If not treated in time, it can cause severe pain, bloody urine, UTIs that can further lead to kidney failure and reduced kidney functioning.
Kidney stones can be prevented by drinking plenty of fluids and making a few dietary changes. Ideally, a person should have a minimum of 8-10 glasses of water a day. If you have a high risk of developing any type of kidney stones, reduce your sodium consumption and the amount of meat eaten.


Kidney Stones - Are They Really Common?

What is diabetic kidney disease?
Diabetic nephropathy, also known as Diabetic Kidney Disease is a type of complication that occurs in people who are a victim to diabetes. That does not mean every individual with diabetes will have this disease, but if the necessary precautions are not taken, then it can lead to this disease. Diabetic Kidney Disease is characterised by excessive amounts of albumin as well as protein in the urine. In diabetics, certain chemicals in the kidneys shoot up and hamper the function of the glomeruli.

The glomeruli are the main units of kidneys that are responsible for the filtration. Diabetic kidney diseases result in the leakage of essential products like albumin and protein into the urine. When this happens, the protein levels in the blood reduce. If proper precautions are not taken and treatment is not done, then the disease may worsen and the condition will progress to  end-stage renal failure .

How to avoid diabetic kidney disease?
The best way to treat diabetic kidney disease is to prevent it in the first place. Foremost, you should prevent the risk factors in order to avoid coming down with Diabetic Nephropathy. The risk factors include high blood pressure, high levels of blood sugar, dyslipidemia and smoking. Avoid excess of following 5S Sugar, Salt, smoke, stress and sedentary life.

Intensive control over blood sugar
According to certain clinical trials, maintaining and keeping a good control over your blood sugar levels drastically reduces the risk of developing diabetic kidney disease. If you are diabetic, make it a point to get your regular checkups and maintain your diet to prevent the levels of sugar in your blood to shoot up. Other things that you must keep in your mind are to take proper medication that has been prescribed to you. You must adhere to your treatment plans and follow the guidelines that have been given to you.

Intensive control over blood pressure
Hypertension is common in patients who are diabetic. Hypertension alone can result in end-organ damage due to excess pressure build up in the blood vessels. Hypertension associated with hyperglycaemia (diabetes) is a ticking bomb for your kidneys. Hence it is advised to keep your blood pressure under control as well to prevent diabetic kidney disease.

Diabetic nephropathy is not something that happens to every individual with diabetes, so if you follow the above simple tips, the chances of the same reduce, and thus the quality of your life goes up. Many diabetics will get kidney failure due to causes other than diabetes and that may be treatable. Hence early consult with nephrologist is a must.

Diabetic Kidney Disease - How It Can Be Prevented?

3 Causes of Acute Kidney Failure

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

-Heavy blood loss
-Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
-Injury
-Use of certain drugs
-Dehydration
-Burns
-Heart disease

2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

-Cervical cancer
-Colon cancer
-Bladder cancer
-Kidney stones
-Enlarged prostate
-Prostate cancer

3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

-Scleroderma (an autoimmune disease that affects connective tissues and skin)
-Build-up of cholesterol deposits
-Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
-Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
-Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)



3 Causes of Acute Kidney Failure

The kidneys are a pair of bean shaped organs responsible for blood filtration. It also eliminates waste products from the body. The kidneys are located in the abdomenal cavity of the body and help in keeping a check on the electrolyte level in the body.

Polycystic kidney disease or PKD is a condition in which a number of cysts grow on the kidneys. The cysts are filled with fluid, and if the number or the size of the cyst increases, it can lead to kidney damage and kidney failure. 5% of kidney failures are caused by PKD. PKD does not affect only the kidneys. It can also cause the cyst to grow on other organs, such as liver, pancreas, ovaries, spleen and large bowel. The brain and the heart can also be affected by PKD. If it reaches the brain, an aneurism is caused. Heart murmurs may occur if PKD affects the heart.

Symptoms: Symptoms are visible for those in the 30 to 40 age group; however, it differs from person to person. Back pain or side pain, enlargement of the abdomen, blood in the urine, high blood pressure, and frequent bladder or kidney infections are some of the common symptoms of PKD.

Diagnosis: An ultrasound is the most dependable, affordable and non-invasive way to diagnose PKD. MRI and CT scans can be used to detect the volume of the cyst. It also helps to determine small cysts which cannot be detected by ultrasound.

Treatment: There is no specific treatment for PKD at present. But certain steps and measures can be taken to slow down the growth of the cyst and to control the symptoms.

Prevention: Keeping a check on blood pressure, use of prescribed antibiotics to treat kidney or bladder infection, restricted use of caffeine, and medications to control pain are some of the treatments for relief and for arresting the growth of the cyst. Research also shows that drinking plenty of water throughout the day can also slow down the growth of the cyst. A diet low in fat and moderate in calories is recommended.

Types: Autosomal dominant kidney disorder is a genetic disorder and is passed on to the child from the parent by dominant inheritance. It is the most common type of PKD. The symptoms are visible after the age of 30 to 40. Infantile or autosomal recessive PKD is a genetic disorder and is inherited by the child from the parent by recessive inheritance. The symptoms are visible during the early months of life or in the womb. It is a rare form of PKD and occurs in 1 out of 25,000 people. Acquired cystic kidney disease occurs due to long-term kidney damage and is linked with kidney failure and dialysis. The bleeding of the cyst causes the bleeding in the urinary system and leads to urine discolouration.

Poly Cystic Kidney Disease - How You Can Prevent it?

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