Kidney cancer or renal cancer is when kidney cells grow uncontrollably and form a tumour. Kidney cancer often begins in the tubules (tiny tubes in the kidneys). The prognosis may depend on the stage of the kidney cancer.

Different Stages of Kidney Cancer
The TNM system helps to categorize each stage of the kidney cancer.
Tumour (T)   Describes the size and location of the tumour.
Node (N)   Describes the spread of cancer to lymph nodes.
Metastatis (M)   Describes the spread of cancer to other body parts.

These results combined with the five stages (0 and 1 to 4) can help to identify the right treatment option for every patient. Zero stage describes no cancer presence. For instance  
Stage 1   Here the tumour is confined to kidneys and its size is smaller than 7 centimetres. (T1 or T1, N0, M0)
Stage 2   Here the tumour is confined to kidneys and its size is more than 7 centimetres. (T2)
Stage 3   Here the tumour is in kidneys or blood vessels or fatty tissues but also a lymph node; cancer spreads to major veins but doesn t extend beyond renal or Gerota s fascia (connective tissues surrounding adrenal glands and kidneys). (T3)
Stage 4   Here the cancer is in the fatty tissues surrounding kidneys and adjacent lymph nodes; has spread to other nearby organs and beyond renal fascia. (T4)

Treatment and management of kidney cancer
Once your doctor has determined the staging of your kidney cancer, a treatment plan can be formulated for you.

Surgery
Simple nephrectomy removes the affected kidney.
Radical nephrectomy is a common surgery for kidney cancer. It removes all affected parts such as the kidneys, adrenal gland, lymph nodes and surrounding tissues.
Partial nephrectomy is for small tumours and removes the kidneys and the surrounding tissues.
Interventional radiology: This is a surgery aided by real-time images. An advanced surgery using a nano knife is minimally-invasive and is effective for inoperable kidney tumours.
Targeted therapy: Drugs target specific tumour cells and destroy them.
Immunotherapy: Used for kidney cancer that has spread to other organs, this therapy may use different types of drugs to either help immune cells find cancer growth or regulate the immune system activity to stop or slow cancer growth.
Arterial embolization: It is a procedure to stop blood supply to the kidney tumour, in order to shrink it in size prior to surgery.
Cryotherapy: This procedure involves using extreme cold to kill cancer cells.
Chemotherapy is not very effective for treating kidney cancer. Talk to your doctor about all possible treatment options for your cancer. You can lower your risk of kidney cancer by eating healthy, maintaining your ideal body weight and managing your blood pressure.

Stages Of Kidney Cancer - How They Can Be Managed?

Breast cancer is a type of cancer, which occurs due to the development of cancerous cells in breasts. Women are usually affected by breast cancer and breast cancer is one of the most common forms of cancer after skin cancer. Usually fatal if not diagnosed in its early stage, breast cancer is a very serious medical ailment. Read on more to find all about the different symptoms, causes, preventive measures and treatment of breast cancer.

Symptoms
Breast cancer has few distinct characteristics and if you have a few or all the following symptoms you could be more likely to suffer from breast cancer. 
a) The formation of a lump in your breast, which is different from the surrounding tissue and usually more thickened.
b) The discharge of bloody fluid  material from the nipples.
c)  Sudden change of the size, shape and appearance of the breast.
d) Certain distinct changes to the skin over the breast for example an indentation in the skin similar to that of a dimple.
e) Appearance of an extra nipple which is inverted.
f)  If the darkened area around the nipples known as the areola is flaking or peeling off.
 
Causes
Studies and researches remain inconclusive on what causes breast cancer. Breast cancer occurs due to abnormal division of the cells located in the breast, which over time accumulate and form lumps. They
might spread to other parts of the body. Breast cancer is caused mainly due to a complex interaction of personal genetics, environment and lifestyle choices. Breast cancer can also be caused due to genetics as about 5% to 10% of cases are due to gene mutations which pass onto generations.

Risk factors
There are certain factors, which increase the probability of contracting breast cancer. Increasing age, personal and family history of breast cancer, obesity, radiation exposure, pregnancy at an older age, postmenopausal hormone therapy are some of the factors that increase the chances of breast cancer.

Treatment
Several forms of surgical methods exist to treat breast cancer. Depending on the condition and spread of the disease a suitable surgery is performed. These include mastectomy, lumpectomy, axillary lymph node dissection and removal of both breasts. Other forms of treatment include chemotherapy or the use of high doses of drugs to destroy cancerous cells. Radiation therapy where X-rays are used to destroy the cancer cells is also effective.

All About Breast Cancer

Hydrocephalus is a condition that is also called  water on the brains . This condition is triggered in children when the cerebrospinal fluid (CPF) isn t drained completely from the brain. This fluid surrounds and protects the brain and the spinal cord and when it doesn t find an outlet, it accumulates in the brain.

Very young children with hydrocephalus have enlarged heads to accommodate all the excess water. But older children whose skull bones have solidified and cannot expand suffer terrible headaches. This condition requires immediate treatment or it could lead to damage to the brain.

What triggers Hydrocephalus? 

If there is an obstruction in the ventricles (the passages through which the CPF flows), the circulation of this fluid is affected. And this triggers hydrocephalus.

Hydrocephalus can be of two types-

Congenital Hydrocephalus:

This is a congenital condition, which means the baby is born with this ailment. It could be because there are abnormalities in the spine or it did not develop the way it should have or because the aqueduct that connects the ventricles of the brain is narrowed.

Acquired Hydrocephalus:

This condition can develop at any age. It is triggered by bleeding in the brain. It may happen if babies are born before the due date. Or a brain injury may prompt it. A tumour could also be behind hydrocephalus.

What are the Symptoms of Hydrocephalus?

Among babies, the biggest sign is the swollen head. Other symptoms may include-

Bulges along with the skull

The gap along with the bone plates of the skull

Swollen veins on the head

Eyes may bulge

Vomiting, nausea and loss of appetite.

Seizures

Drowsiness

squinting

Treatment of Hydrocephalus -

This condition requires immediate treatment or it might trigger problems of the nervous system. Here are some treatments that a child might have to undergo-

Shunt procedure -

A catheter is inserted into the brain to drain away the excess fluid. It is passed through the abdominal cavity and the bloodstream absorbs it.

Endoscopic surgery -

This surgery is performed on older children. A lighted stick with a camera is inserted by drilling a tiny hole into the third ventricle. This allows the accumulated fluids to flow out and past the blockages. This is a minimally invasive procedure.

The child is kept under meticulous observation after the surgery. Hydrocephalus is a dangerous ailment but with timely intervention, it can be cured completely.

What Triggers Hydrocephalus In Children?

It is very common for women to have heavy and painful periods or have a feeling of fullness in the lower abdomen. Although, it may not sound very alarming these could be the symptoms of uterine fibroids. These are the most common types of benign tumours found in women. The fibroids are basically some tissues and muscle cells that grow within the uterus, outside the uterus, or along the wall of the uterus. The fibroids are usually benign and asymptomatic and do not require any treatment unless they cause problems. 

Know the causes 

Though the exact cause of fibroid formation is not known, it is believed that the female hormones estrogen and progesterone have a role to play in their formation. Fibroids are formed only when a woman is producing these hormones and they are not seen in women in non-reproductive age i.e. before starting of menses or after stoppage of menses (menopause). If fibroids are persisting even after menopause or especially if increasing in size then it is an alarming sign. Such a fibroid needs to be taken care of immediately. 

What are the symptoms? 

Fibroids often remain quiet for long periods of time. They cause nonspecific symptoms in the pelvis and abdomen including: 

Fullness in the abdomen 
Low back pain 
Irregular menstruation 
Cramping with menstruation 
Painful sex 
Increased urgency to urinate 
Anemia, leading to tiredness and weakness 
Infertility Diagnosing the fibroids 
When these symptoms are recurrent, it is good to confirm the diagnosis. This can happen with a pelvic exam followed by ultrasound scanning to confirm the size and location of the fibroids. A blood test also may be done to confirm anemia, which is common due to heavy periods.

Treatment Options 

Management of fibroids can range from doing nothing to periodic monitoring to surgical removal. 

If pain and heavy bleeding are the only symptoms, then pain killers like ibuprofen should suffice for symptomatic relief. Anemia, if severe, may require iron supplementation. 
Embolization is an option which shrinks the fibroid, at the same time preserving the uterus. The blood flow to the fibroid is cut off, thereby preventing its further growth. It takes about 1 to 3 hours and requires some bed rest after the procedure. There could be some pelvic pain and vaginal bleeding, which will gradually subside. The fibroids may grow back, but the benefits of keeping the uterus are definitely there. This is suitable in case of single fibroid with specific blood supply. 
The next surgical option is myomectomy, where the portion of the uterus which contains the fibroid alone is removed. This is done in women who still wish to get pregnant and in women who would like to retain the uterus. This can also be achieved laparoscopically( key hole surgery). In such cases, fibroids are cut into small pieces and then removed from the body. This procedure should be done by a doctor specialised in advanced gynecological endoscopy as all this cutting should be done in a bag to avoid any spillage of cells inside the abdominal cavity. This procedure is known as Laparoscopic Myomectomy with In-bag Moecellation. 
In women who have crossed their pregnancy phase, hysterectomy or complete removal of the uterus is advised. In these women, the bleeding and pain may not have subsided even after years of treatment with hormones. The growing fibroids could be pressing on the adjacent organs, causing pressure. This is the only definitive treatment and should be done in women have completed their family and don t desire to be pregnant. 
Myomectomy and hysterectomy may be done laparoscopically or with an open method depending on the overall health, the size and location of the fibroids in the uterus.

Uterine Fibroid - How Removing Them Will Help You?

Peripheral arterial disease or commonly known as PAD is a common cardiovascular disease. Despite having the power to cause painful symptoms and severe health risks, it is overlooked by many. This particular arterial disease may lead to life-threatening consequences if left untreated for long. Read on to know more about the condition.

What is PAD?
PAD refers to the situation where in the peripheral arteries to the arms, head, stomach, and legs become narrow. Often referred to as the peripheral vascular disease, here, the arteries start to grow narrower due to the slow but constant buildup of fatty deposits on the artery walls. Though it can affect all the arteries in a person s body, except those that supply blood to the heart, in the majority of cases, it affects the arteries in the leg.

What are the threats it poses?
PAD is indeed a life-threatening disease, as the blockages, it creates in the peripheral arteries prevent normal blood circulation to the different organs, legs, and brain. And when the blood flow is restricted, or the vital organs of the body fail to receive necessary blood flow, then the legs, brain and all the vital organs suffer severe damage. And when PAD continues to harm the blood flow for a long time, then it leads to tissue infection or tissue death, which is known as gangrene.

Additional health issues it causes
PAD also creates various other health concerns, such as atherosclerosis. Atherosclerosis is a chronic disease of fatty materials  build up. In the case of atherosclerosis, the entire blood circulatory system gets damaged, including the arteries leading to the heart. The risk of blood clot build ups and vascular inflammation are also common additional threats posed by the fatty deposits.

Probable symptoms
Depending on the part of the body that is affected, the PAD symptoms vary from one to another. However, painful cramping in the muscles of one s legs is the most common symptom of this condition. The pain, originating in the legs often goes up to the muscles in the thighs or hips too. Except this, weakness or numbness in the legs, ulcers or open sores on the feet or legs, skin color changing into bluish or pale are some of the other symptoms of PAD.

Possible treatments
The peripheral arterial disease can be diagnosed easily, painlessly and straightforwardly under proper medical attention. Both prescribed medications and a lifestyle change are considered to be the best treatment for controlling PAD. Including a healthy diet and adopting a healthy lifestyle have often been successful in preventing PAD in its early stage.

The moment any signs or symptoms of PAD is noticed one should not be late in seeking immediate medical attention.

Peripheral Arterial Disease- A Serious Threat To Life Worth Being Concerned About!

Cancer is the abnormal, uncontrolled growth of cells in a particular body part. With continued growth, pieces of this tissue travel through the blood to different body parts and continue to grow in the new area. This is known as metastases. Breast cancer is one of the most common forms of cancer and affects about 1 in 8 women in the USA. Read on to know more details of breast cancer   breast anatomy, causes, symptoms, risk factors, detection, prevention, and of course treatment.

Anatomy: The main function of the breast is lactation through its milk-producing tissue that are connected to the nipple by narrow ducts. In addition, there is surrounding connective tissue, fibrous material, fat, nerves, blood vessels and lymphatic channels which complete the structure. This is essential to know as most breast cancers develop as small calcifications (hardened particles) in the ducts or as small lumps in the breast tissue which then continues to grow into cancer. The spread can happen through lymphatic or blood flow to other organs.

Warning signs/symptoms: The following are some symptoms that need to be watched out for if you have a predisposition to breast cancer.

    A lump in either of the breasts or armpits
    Change in size, shape, or contour of either breast
    Redness of your breast or nipple
    Discharge of clear or bloody fluid
    Thickening of breast tissue or skin that lasts through a period
    Altered look or feel of the skin on the breast or the nipple (dimpled, inflamed, scaly, or puckered)
    One area on the breast that looks very different from the other areas
    Hardened area under the breast skin

Either one or a combination of these should be an indication to get a detailed checkup done. Early diagnosis results in controlling the disease with minimal treatment and reduced complications.

Causes and risk factors: The exact cause for breast cancer is yet to be pinned down. However, risk factors are clearly identified, and women with risk factors need to watch out for warning signs.

    Family history: Of all the risk factors, the family history is the most important. Breast cancer runs in families, and if there is a first-degree relative with the breast cancer, the chances of developing it are almost double. Two genes BRCA1 and BRCA2 are the carriers of the disease, and this testing can be done in women to identify if they are at risk.
    Family history of other cancers: Even if there is no breast cancer, if there are other cancers that run in the family, watch out.
    Age: Women over 50 are at higher risk of developing breast cancer.
    Race: Caucasian and Jewish women are at higher risk of breast cancer than African-American women.
    Hormones: Greater exposure to the female hormone estrogen increases the chances of developing breast cancer. Women who use birth control pills for contraception and hormone replacement after menopause are at a higher risk of developing breast cancer.
    Gynecologic milestones: Women who have abnormal menstrual milestones need to watch out. These include those who attain menarche before 12 years of age, get pregnant after 30, attain menopause after 55, and have menstrual cycles shorter than 26 days or longer than 29 days.
    Obesity and alcohol abuse are also likely to increase a woman s chances of developing breast cancer.

Stages: Starting from stage 0, higher stages indicate advanced disease.

    Stage 0: The growth which has begun in the milk-producing tissue or the ducts has remained there (in situ) and not spread to any other area, including the rest of the breast.
    Stage I: The tissue slowly becomes invasive and has begun to affect the surrounding healthy tissue. It could have spread to the fatty breast tissue and some breast tissue may be found in the nearby lymph nodes.
    Stage II: The cancer at this stage grows considerably or spreads to other parts. There are chances that cancer may grow and also spread.
    Stage III: It may have spread to the bones or other organs but small amounts are present in up to 9 to 10 of the lymph nodes in the armpits and collar bones which makes it is difficult to fight.
    Stage IV: The cancer is widespread to far-flung areas like the liver, lungs, bones, and even the brain.

Screening: This is one of the most effective ways to identify the disease in its early stages. This will help in controlling cancer from spreading with minimal treatment.

    Self-examination: A thorough self-examination to look for changes in terms of shape, size, colour, contour, and firmness should be learned by all women. Watch for any discharge, sores, rashes, or swelling in the breasts, surrounding skin, and nipple. Examine them while standing and when lying down.
    In most women, annual screening mammograms are advised after the age of 40. However, in women who have a strong family history or genetic makeup, it is advisable to have screening mammograms starting at age 20 every 3 years and then annually from the age of 40.
    Women in high-risk categories should have screening mammograms every year and typically start at an earlier age.
    Ultrasound screening can also be given in addition to mammograms.
    Breast MRI is another way to screen for breast cancer if the risk is greater.

Breast Cancer Prevention: Now that there is so much awareness about causes and risk factors, there are definitely ways to prevent or delay the onset of the disease.

    Exercise and a healthy diet with reduced amount of alcohol are definitely effective in minimising the chances of developing cancer.
    Tamoxifen is used in women who are at high risk for breast cancer.
    Evista (raloxifene) which is used to treat osteoporosis after menopause. It is also widely used in preventing breast cancer.
    In high-risk women, breasts are surgically removed to prevent the development of cancer (preventive mastectomy).

Treatment: As with all cancers, treatment would depend on the stage at which it is identified and include a combination of chemotherapy, radiation, and surgery. As noted earlier, if you are at risk, look out for warning signs as early diagnosis is the key to maximum recovery.

Breast Cancer - Know More to Say 'No' More!

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