Uterine cancer of cancer of the uterus is a fairly common type of cancer. In fact, this is the fourth most common type of cancer to affect women. This type of cancer is usually diagnosed in its early stages and hence can be easily treated. However, did you know that this type of cancer can be prevented? This is primarily because most cases of uterine cancer are caused by an increased amount of estrogen as compared to progestin. Here are a few tips to keep in mind.

Birth control pills: The regular use of birth control pills for at least a year is believed to reduce the risk of uterine cancer by at least 50%. The longer these contraceptives are used for, the more effective they are. The protection provided by them lasts for 15 years after their use has been discontinued.
Reduce weight: Being overweight not only increases the risk of lifestyle diseases such as diabetes and high blood pressure but can also increase a woman s risk of suffering from uterine cancer. This is because fat cells produce estrogen that further dis-balances the estrogen to progestin ratio. Reducing weight can thus help lower the estrogen levels in the body and prevent cancer. To lose weight, one must keep a strict control over portion sizes, eat nutritious food and exercise regularly.
Use an IUD: Some methods of contraception not only prevent unwanted pregnancy but also reduce the risk of uterine cancer. Many IUDs or Intrauterine Devices contain progestin. This helps balance the estrogen and progestin levels in the body. Additionally, it also reduces the risk of hyperplasia. This is a condition marked by the abnormal thickening of the lining of the uterus. In many cases, this condition is a precursor to uterine cancer.
Question Your Family: Genetics can also influence the risk of developing uterine cancer. For example, people carrying the gene responsible for Lynch Syndrome or hereditary nonpolyposis colorectal cancer have a much higher risk of uterine cancer as compared to others. Thus, if you know of family members who have suffered or are suffering from uterine or colon cancer, it is a good idea to undergo genetic testing.
Broccoli - A super food: Some foods can also help strengthen the immune system and reduce the risk of uterine cancer. Broccoli is one such vegetable. This is known as a super food that can prevent cancer. The best way to eat broccoli is by steaming it. This has the higher amounts of glucosinolate as compared to fried or boiled broccoli.

Uterine Cancer - 5 Tips To Help You Keep It At Bay!

Peripheral arterial disease or commonly known as PAD is a common cardiovascular disease. Despite having the power to cause painful symptoms and severe health risks, it is overlooked by many. This particular arterial disease may lead to life-threatening consequences if left untreated for long. Read on to know more about the condition.

What is PAD?
PAD refers to the situation where in the peripheral arteries to the arms, head, stomach, and legs become narrow. Often referred to as the peripheral vascular disease, here, the arteries start to grow narrower due to the slow but constant buildup of fatty deposits on the artery walls. Though it can affect all the arteries in a person s body, except those that supply blood to the heart, in the majority of cases, it affects the arteries in the leg.

What are the threats it poses?
PAD is indeed a life-threatening disease, as the blockages, it creates in the peripheral arteries prevent normal blood circulation to the different organs, legs, and brain. And when the blood flow is restricted, or the vital organs of the body fail to receive necessary blood flow, then the legs, brain and all the vital organs suffer severe damage. And when PAD continues to harm the blood flow for a long time, then it leads to tissue infection or tissue death, which is known as gangrene.

Additional health issues it causes
PAD also creates various other health concerns, such as atherosclerosis. Atherosclerosis is a chronic disease of fatty materials  build up. In the case of atherosclerosis, the entire blood circulatory system gets damaged, including the arteries leading to the heart. The risk of blood clot build ups and vascular inflammation are also common additional threats posed by the fatty deposits.

Probable symptoms
Depending on the part of the body that is affected, the PAD symptoms vary from one to another. However, painful cramping in the muscles of one s legs is the most common symptom of this condition. The pain, originating in the legs often goes up to the muscles in the thighs or hips too. Except this, weakness or numbness in the legs, ulcers or open sores on the feet or legs, skin color changing into bluish or pale are some of the other symptoms of PAD.

Possible treatments
The peripheral arterial disease can be diagnosed easily, painlessly and straightforwardly under proper medical attention. Both prescribed medications and a lifestyle change are considered to be the best treatment for controlling PAD. Including a healthy diet and adopting a healthy lifestyle have often been successful in preventing PAD in its early stage.

The moment any signs or symptoms of PAD is noticed one should not be late in seeking immediate medical attention.

Peripheral Arterial Disease- A Serious Threat To Life Worth Being Concerned About!

The uterus is an organ situated in the pelvis of a female. It is hollow and is usually called the womb where child conception takes place. The uterus functions to help in developing the foetus until birth. Abnormal cell growth that consists of uterine tissues causes uterine cancer.

Although the exact reason for uterine cancer is not known, the risk factors usually can be seen in women with hyperplasia, obese women, and women who have never had kids. Common signs and indications of uterine cancer are unusual vaginal bleeding or discharge, pain while urinating and having sex, and pelvic pains.

Bases upon the sort and phase of cancer, and also your concerns about fertility, there are a number of uterine cancer surgical methods, including the following:

Hysterectomy: The primary focus is an operation to remove the uterus and cervix. At the point when the uterus is removed through a cut in the abdomen, it is known as a total abdominal hysterectomy. In case that the uterus is removed through the vagina, it is known as a vaginal hysterectomy.

Radical Hysterectomy: A radical hysterectomy will be necessary for only a small percentage of women since several better surgical options exist already. This kind of uterine cancer surgery includes removing the uterus, cervix and ovaries and the majority of the encompassing tissue (the parametria) and the upper part of the vagina.

Lymphadenectomy: The lymph nodes in the pelvis may likewise be removed. Your specialist may evacuate the lymph nodes as a component of a hysterectomy to deal with cancer and build up a more focused approach for the uterine cancer treatment plan.

Pelvic Exenteration: For women with repetitive or advanced uterine cancer, pelvic exenteration might be an alternative. During this kind of cancer surgery, the uterus, cervix, vagina, ovaries, bladder, rectum and surrounding lymph nodes are removed. Tissue from somewhere else in the body is used to recreate the vagina and urine and stools are passed into external packs.

Sentinel Lymph Node Mapping: Sentinel lymph node mapping (SLN) might be utilised as a part of early-stage cancer if your specialist can see from the X-ray results that there has been no undeniable spread of cancer to the lymph nodes in your pelvis. In this surgery, a blue dye is infused into the zone with cancer, which is usually close to the cervix. The lymph nodes that turn blue are removed during surgery.

Omentectomy: The omentum is a layer of greasy tissue that covers the stomach contents like an apron. Cancer at times tends to spread to this tissue. At the point when this tissue is removed, it is called an omentectomy. This might be done during a hysterectomy if cancer has spread there or to check for possible cancer spread.
After surgery if the stage comes beyond stage 1 then patients need Radiotherapy by an oncologist.

Surgical Treatments For Uterine Cancer

The human body has 206 bones and bone cancer can affect any of these bones. This condition starts when healthy bone marrow cells mutate and grow out of control to form a tumor. There are many different types of bone cancer. Treatment of bone cancer varies from case to case and depends on factors such as, type of cancer, stage at which it is diagnosed and the patient s overall health amongst other factors.

Surgery, chemotherapy, and radiation are the three most common types of treatments favored for bone cancer. Surgery is usually used for low-grade tumors. This involves the removal of tumor and the surrounding healthy cells and tissues to ensure that that cancer does not recur. For high-grade tumors, surgery may be accompanied by chemotherapy, radiation or a combination of the two. 

Chemotherapy involves the delivery of medication to destroy cancer cells orally or intravenously. Radiation involves the use of high energy X rays to kill cancer cells. This is often used to treat patients with a tumor that cannot be surgically removed.

Apart from these standard forms of treatment, bone cancer patients are often advised to take part in clinical trials for their treatment. This can be described as a research study to test the efficiency of new approaches to the treatment of bone cancer. A clinical trial can be used to treat the safety and efficacy of a new drug, the new dosage of standard drugs or a new combination of treatment types. As a member of a clinical trial, you may be one of the first few people to benefit from treatment even before it is available to the general public. 

Some of the new options available through clinical trials are:

Immunotherapy: This is also known as biologic therapy. It is designed to boost the patient s immune system to fight cancer cells. Mifamurtidesi one of the types of immunotherapy being tested. Immune checkpoint inhibitors such as monoclonal antibodies are also being tested for their ability to block specific molecules.
Targeted therapy: This type of therapy targets the genes and proteins that contribute towards the growth and survival of cancer cells. Targeted therapy limits the damage caused to healthy cells and tissues and only blocks the growth of cancer cells.
Myeloablative therapy: This involves an intense regimen of chemotherapy. High doses of chemotherapy aim at destroying all the cancer cells. Unfortunately, in the process, healthy cells may also be killed. This may be followed by introducing stem cells through a bone marrow transplant to the patient s body to renew blood cells.
Intraoperative radiation therapy: These trials evaluate the use of radiation given inside the patient s body during a surgery. In cases where tumor is in a distant location of the body, stereotactic body radiotherapy and radiofrequency ablation may be used.


Bone Cancer - Understanding The New Approaches For Treatment!

The human skull is composed of several plates and pieces of bones. The roof of the skull is the top of your head. The base of the skull is, however, a complex area. It consists of 5 bones. These bones are also linked to your eye socket, the cavity of the nose, the sinuses and the bones of the inner ear. Surgery through the skull base can be quite complicated as quite a few nerves, blood vessels and opening of the spinal cord pass through this region.

When does Endoscopic Skull Based Surgery become necessary?
An endoscopic skull based surgery is performed to remove tumours of the brain. The tumour might be benign or malignant - this procedure is effective against both. This surgery can also be performed to cure any abnormality on the underside of the brain, the upper vertebrae of the spinal cord or the base of the skull.

Other conditions that may necessitate an endoscopic skull base surgery are -
  Cysts in the brain
  Swelling caused by infections
  Pituitary tumours
  Meningioma
  Chordomas
  Trigeminal neuralgia
  Cerebrospinal fluid fistulas
  Cerebral aneurysm

What to expect during this Surgery?
Since the base of the skull is a complicated region, surgery requires a delicate approach. That is why endoscopy is used. It is a minimally invasive procedure.
Right before the surgery, you will be put under general anaesthesia. Your skull has two natural openings- the nose and the mouth. Usually, the surgeon inserts the minute surgical instruments through the nose or the mouth. Sometimes, a tiny hole is drilled right above the eyebrows. A tiny camera mounted on a lighted tube will be led into your brain through the cavity that will send a live feed from the inside. This will direct the surgeons who will gently remove the growth or fix the abnormalities.
A team of doctors with different specializations such as ENT, radiology, neurosurgery come together to perform this surgery.

Complementary Procedures -
Depending on the kind of tumour being removed or the stage it was detected in, you might have to undergo any of the following in addition to endoscopic surgery-
  Chemotherapy
  Radiation
  Particle Therapy
  Proton Beam Therapy

Post Surgery Care -
After the surgery, you will have to stay in the clinic or hospital for a number of days where your progress will be constantly monitored. You will require therapy and undergo MRI scans.
Endoscopic skull base surgery is very effective in dealing with tumours and abnormalities of the brain or the upper spinal cord. Keep your family and friends around you during the recovery phase as their love and support will help you get back to your normal lifestyle in no time.

Know More About Endoscopic Skull Base Surgery Through Brain!

Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal lung cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and interfere with the functioning of the lung, which provides oxygen to the body via the blood.

Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. According to the U.S. National Cancer Institute, approximately one out of every 14 men and women in the U.S. is diagnosed with cancer of the lung at some point in their lifetime. Lung cancer is predominantly a disease of the elderly; almost 70% of people diagnosed with lung cancer are over 65 years of age, while less than 3% of lung cancers occur in people under 45 years of age.

What Causes Lung Cancer?

The development of lung cancer is strongly associated with cigarette smoking, approximately 90% of lung cancers are attributable to use of tobacco. Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. Tobacco smoke contains more than 4,000 chemical compounds, many of which are cancer causing (carcinogens). Passive smoking, i.e. the inhalation of tobacco smoke by non-smokers who live or work with smokers, is also an established risk factor for the development of lung cancer.

Genetic susceptibility (i.e. family history) may play a role in the development of lung cancer. Other causes of lung cancer include air pollution (from vehicles, industry, and power generation) and inhalation of asbestos fibres (usually in the workplace).

Lung Cancer Symptoms

Early symptoms and signs of lung cancer

There may be no symptoms at the onset of the disease. When present, common symptoms of lung cancer may include:

Coughing: This includes a persistent cough that doesn't go away or changes to a chronic smoker's cough, such as more coughing or pain.
Coughing up blood: Coughing up blood or rust-colored sputum (spit or phlegm) should always be discussed with your doctor.
Breathing Difficulties: Shortness of breath, wheezing or noisy breathing (called stridor) may all be signs of lung cancer.
Loss of Appetite: Many cancers cause changes in appetite, which may lead to unintended weight loss.
Fatigue: It is common to feel weak or excessively tired.
Recurring infections: Recurring infections, like bronchitis or pneumonia, may be one of the signs of lung cancer.
Signs of advanced stages of lung cancer

Advanced stages of lung cancer are often characterized by the spread of cancer to distant sites in the body. This may affect the bones, liver or brain. As other parts of the body are affected, new lung cancer symptoms may develop, including:

Bone pain
Swelling of the face, arms or neck
Headaches, dizziness or limbs that become weak or numb
Jaundice
Lumps in the neck or collar-bone region
Treatment

Treatment for cancer involves a combination of surgery to remove cancer cells, chemotherapy and radiation therapy to kill cancer cells. Lung cancer is incurable unless complete surgical removal of the tumour cells can be achieved. Surgery is the most effective treatment for lung cancer, but only a few percentage of lung cancers are suitable for surgery i.e. Stage I and II NSCLC and cancer that has not spread beyond the lung.

Radiation therapy may be used for both NSCLC and SCLC and is a good option for people who are not suitable for surgery or who refuse surgery. Chemotherapy is used for both NSCLC and SCLC. Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. Chemotherapy is the treatment of first choice for SCLC since it has usually spread extensively in the body by the time it has been diagnosed.

Also used in the treatment of lung cancer are targeted therapies. These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression. They are used in some patients with NSCLC that does not respond to standard chemotherapy.

Lung Cancer: Causes, Symptoms and Treatments

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