Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

Those two, small bean-shaped organs are indeed essential for a perfectly healthy life. To check if a person is dead or living, medical practitioners need to confirm response from three organs of the human body heart, brain and kidneys. Kidneys absorb impurities from the blood, thus, purifying it and lead to the production of urine. Urine is necessary to rid your system of body wastes. Kidneys play a key role in maintaining hormone balance. The presence of any factor that could impede free functioning of this organ should be diagnosed, treated and eliminated at the earliest possible. Kidney diseases and subsequent kidney failure see no age bar. It affects both young and old people. In case of younger folks, the symptoms take years to surface and thus the chances of a fatal outcome are even higher.

Causes of kidney failure at a tender age:

    Chain smoking is a trigger: Smokers suffer from a higher risk of kidney failure. Smoking is a bad habit that has engulfed almost ninety percent of young adults. Irrespective of awareness programs and warning messages, there are millions who smoke nonchalantly. Smoking is known to impair kidney function which again can have frightening implications.
    High blood pressure levels must be controlled: Since stress is a common phenomenon among most individuals high blood pressure is also prevalent among a majority of these individuals. Younger people suffer from high blood pressure due to workplace politics and familial tensions. High blood pressure should not be taken lightly. Exercising and regular medications should be opted for in order to counter the threat of kidney failure at a young age.
    If you are obese, you are stepping closer to the threat: If not optimal; being close to the optimal body weight is very necessary to keep health disorders in check. If you are obese, you are not safe; one must make efforts to lose weight or else face the alarming situation when his or her kidneys fail to function properly.
    Consumption of junk food can cause complications: Junk food is fatty. One must keep away from high-protein and high-fat diet. Food items rich in protein and fats can push you towards chronic kidney diseases.
    Genetics may discern the health of your kidneys: The incidence of kidney failure in your family history can make you prone to a similar condition. Extra care should be taken to avoid any such possibility. Regular health check-ups should be undertaken.

Why You May be at the Risk of Kidney Failure at an Early Age

3 Causes of Acute Kidney Failure

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

-Heavy blood loss
-Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
-Injury
-Use of certain drugs
-Dehydration
-Burns
-Heart disease

2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

-Cervical cancer
-Colon cancer
-Bladder cancer
-Kidney stones
-Enlarged prostate
-Prostate cancer

3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

-Scleroderma (an autoimmune disease that affects connective tissues and skin)
-Build-up of cholesterol deposits
-Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
-Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
-Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)



3 Causes of Acute Kidney Failure

One single kidney in place of two is a scenario which is often termed as solitary kidney.

Who has a solitary kidney?

Their body functions normally and are generally not unhealthy. This is also known as renal agenesis.
In some cases, people are born with two kidneys with just one of them healthy and fully functional. The other one does not function fully or partially. This condition is known as kidney dysplasia.
A person who had to undergo a kidney removal surgery (nephrectomy); such a surgery is conducted when a person has an infected kidney or diseased, malfunctioning/cancerous growths on the kidney.
A person who has donated a kidney to someone who required kidney transplantation.
What potential health risks does a person with a solitary kidney have?

Normally, a person born with a single kidney does not have any such potential health risks. They are generally healthy and lead normal lives.
Later in life, there may or may not be slight loss or degradation in the functioning of the kidney.
The life span of a person with a single kidney is normal. There is no apparent effect on the mortality rates.
What kind of special diet must a person with a single kidney follow?

There is no need of any such special diet for a person with a single kidney.
Normal healthy balanced diet with all the essential nutrients should suffice.
You must be careful about your animal protein intake and calcium supplements.
Drink sufficient quantity of water to remain hydrated all day and prevent the urine from turning acidic.
Controlled consumption of alcohol and caffeine is a must. It is also important to reduce the consumption of aerated drinks.
Exercises and Physical activities for a person with a single kidney:

A person with a solitary kidney can function like any other normal individual.
You may also participate in sports. However, you must take enough precaution to prevent injuries to your kidney. Proper padding and protection around your lower abdominal region and back is of utmost necessity.
You can hit the gym, run a marathon and nothing is impossible for you.

Living With Solitary Kidney - Things You Need to Know!

Often, early stages of kidney diseases do not come with specific signs and symptoms and most people will remain unaware of their condition. However, certain symptoms may be perceived that may indicate that a person is suffering from early stages of kidney failure. When you are diagnosed with kidney failure (also known as renal failure) in the initial stages, certain measures can be taken to retard the progression of the renal disease. This can also help reverse the condition and improve the quality of life of the patient. On the basis of a typical cause, the symptoms of kidney failure are grouped into specific categories that are given below. If you notice any of the specified renal failure symptoms, it is recommended to immediately fix up an appointment with your doctor and get your diagnostic tests done. 

Symptoms of Renal Failure from the accumulation of waste products in the body: 

Metallic taste in mouth 
Nausea and vomiting 
Facing difficulty in concentrating 
Loss of appetite 
Aversion towards meat (protein aversion) 
Itching or pruritus 
Symptoms of Renal Failure from the accumulation of fluid in the body: 

Dyspnoea or shortness of breath (this happens due to the accumulation of fluid in the lungs).
Swelling is seen in the feet, hands or face. 
Symptoms of Kidney Failure from damage to the kidneys: 

The amount of urine production changes, though it is not a reliable sign Haematuria or blood in the urine (usually in microscopic quantity). 
Frothiness or foam in the urine (usually happens when protein is present in the urine). 
Symptoms of Kidney Failure due to decreased blood production (anemia): 

Dyspnoea or shortness of breath. 
Fatigue Weakness. 
Confusion If you happen to feel cold all the time. 
The following diagnostic tests will be performed by your doctor in order to determine whether the symptoms are the manifestation of a kidney failure or not: 

Urine analysis - In this test, a sample of your urine is tested to find traces of blood, white blood cells or proteins which may indicate a problem in kidney function. 
Blood Tests - This includes tests for BUN and creatinine in the blood which are usually removed from the blood if the kidneys function properly. 
Actions must be taken when you show signs and symptoms of kidney failure: 

It is common that the symptoms of early renal failure are not always prominent, but if any of the above symptoms are witnessed, it is recommended to met a physician to determine whether they are caused by a kidney disease. You can pen-down the symptoms that you feel are related and bring it to the doctor when you fix up the next appointment. It is essential to know about your disease at the earliest as it will give you time and the ease of taking measures to retard the damage process and will decrease or delay the probability of undergoing dialysis or kidney transplant.

Kidney Failure - What Should You Know About it?

Acute kidney failure is the kidney's inability to filter waste from the blood. As soon as the kidney loses the filtering ability, a humungous amount of body waste gets accumulated in the kidney and the chemical makeup of the body goes out of balance. Kidney or renal failure can progress tremendously from hours to days. This is a condition that is mostly witnessed in critical patients who are already hospitalized. This condition can prove to be fatal but can be reversed with treatment and medication. Here is a list of things one should do whilst suffer from kidney failure:

Lifestyle and dietary adjustments
During the phase of recovery, the medical team might assist a patient to go a special diet and limit the activity of the kidney so that they get the required time to heal. A nephrologist often routes this cases to a dietician or carefully analyses the present diet to lock up on the diet required for a speedy recovery:
Lower amount of potassium in food: Food with low potassium content is often recommended by the doctor. It ensures that kidney does not stress itself. Foods to avoid include spinach, bananas, oranges, tomato and potato. Some of the foods that need to be included in the diet are cabbage, strawberries, apples and grapes. Furthermore, food must be consumed in small quantities but in multiple servings.
Limit the amount of phosphorus in food: Phosphorus is found in abundant quantities in food items such as peanut butter, milk, dried beans, cheese and nuts. Along with skin itchiness, phosphorus can weaken the bone as well. A dietitian might share special instructions on how to cut down the amount of phosphorus and the substitute food to counter the effect of the above-mentioned ones.
Avoid salty products: It is extremely necessary to cut down food items that contain an excess amount of salt in it. Food products such as the canned soup, frozen dinner, and fast food are the major culprits in worsening the condition. Processed meats and cheese are equally bad.

Preventive measures to avoid kidney failure:

OTC pain medications: It is necessary to check the label of over the counter pain medications. Consumption of too many OTC medications can result in kidney failure. A pre-existing kidney condition can further aggravate this condition.
A healthy lifestyle: A sensible lifestyle with simple diet can do wonders for a kidney to be healthy in the long-term. Some of the other things to keep in mind include doing regular exercise, refrain from alcohol or drug abuse and remain active throughout the day.
Consult a doctor: Even a hint of a kidney problem should be discussed with a doctor to ensure that even the smallest of problems can be addressed at the earliest. 

Acute Kidney Failure - What Should You Do In Such A Case?

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